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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
    November 01, 2013 - Chan, et al. compared the contents of 102 trial protocols approved by the scientific ethics committees … Studies identified in FDA documents should be compared with those found in the published literature … compared 12 of 20 internal pharmaceutical company documents with their published versions (1999-2006 … Agreement of data in abstracts compared to full publications. … Comprehensive When Compared to Other Sources?
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
    January 01, 2010 - analyses suggest that MRSA infections are associated with increased mortality and cost of care when compared … outcomes and increased expense in managing patients with surgical site infection due to MRSA when compared … comparative effectiveness of a MRSA- screening strategy (screen, isolate, eradicate/decolonize)—when compared … comparative effectiveness of a MRSA- screening strategy (screen, isolate, eradicate/decolonize)—when compared … comparative effectiveness of a MRSA- screening strategy (screen, isolate, eradicate/decolonize)—when compared
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
    June 12, 2013 - e.g., differences in the biologically effective dose [BED] that can be safely delivered with SBRT compared … The relative economic palatability of RFA, compared to SBRT or PBRT, is beyond the scope of this report … likely is the significant difference in the BED of radiation that can be safely delivered by SBRT, compared … any conformal RT modality can be associated with better clinical outcomes such as overall survival, compared … ascertain whether a higher BED delivered by SBRT is associated with differences in patient outcomes compared
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
    March 31, 2010 - The team phrased the questions as high-priority interventions compared with no intervention, (rather … than compared with another active intervention). … The questions about settings were phrased as high-priority settings compared with other high-priority … multi-setting parent-targeted randomized controlled intervention on the primary outcome, child BMI, compared … recommended levels in adolescent females with habitually low calcium intake will decrease body fat gain compared
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
    August 01, 2012 - What is the effectiveness of nitrous oxide when compared with other methods for the management of … Within each KQ, evidence is organized by aspects of the question, such as the compared intervention … Only one study compared nitrous oxide with placebo and found no significant difference in pain scores … Effect of Nitrous Oxide on the Route of Birth Six studies compared the route of birth in women who … Sevoflurane compared with Entonox for labour analgesia. Br J Anaesth. 2007 Jan;98(1):110-5. 13.
  6. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - the rate of antihypertensive treatment success based on use of a single antihypertensive for ARBs compared … Only nine studies compared ACEIs and ARBs for periods longer than 1 year.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - Clinical reviews have compared safety of a few but not all drugs. 34, 35 No systematic reviews have … How do preventive pharmacological treatments affect patient-centered and intermediate outcomes when compared … treatments combined with nondrug treatments affect patient-centered and intermediate outcomes when compared … What are the harms from preventive pharmacologic treatments when compared to placebo or no active treatment … What are the harms from preventive pharmacologic treatments when compared to active treatments?
  8. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
    February 17, 2016 - reoperation), but high strength of evidence that pharmacologic VTE prophylaxis reduces the risk of DVT compared … during the surveillance review; thus, conclusions and strength of evidence are unlikely to change compared … These clots tend to be relatively large and may be more liable to embolize to the lungs, compared to … Network MA: A meta-analysis in which multiple treatments are compared using both direct comparisons
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
    May 01, 2013 - Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease … rates of major adverse cardiac and cerebrovascular events continued to favor treatment with CABG compared … infarction, stroke, or repeat revascularization at one year was higher in patients treated with PCI compared … including 1,611 patients Target vessel revascularization was higher in patients treated with PCI compared
  10. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Inhaled insulin has not been compared to injected insulin in large randomized, controlled trials. … Compared to the medical management group, the surgery group had lower HbA1c (6.2 vs. 7.8; p=0.002), … Severe hypoglycemic events occurred in 5.1% (n=177) of the Afrezza group compared to 1.7% (n=176) of … One research expert noted, “When compared with intra-vitreal injections of anti-VEGF drugs over a 2 … However if fewer visits are anticipated compared to current treatments, then number of staff might
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
    January 01, 2010 - While the literature suggests that CSII with the insulin pump, when compared with MDI, lowers HbA1c … We found one systematic review of randomized controlled trials (RCTs) published in 2007 that compared … There was a statistically significant increase in mean birth weight associated with CSII when compared … insulin per day. 2. rt-CGM would be compared with SMBG, which will be defined as at least three … Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - Differences between individuals selected for one arm of a study, when compared with those selected for
  13. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - Differences between individuals selected for one arm of a study, when compared with those selected for
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
    October 01, 2012 - with serum levels rising at the onset of infection and falling rapidly as the infection resolves, as compared … criteria for infection to guide initiation, discontinuation, or a change of antibiotic therapy when compared … Results Overview Eighteen RCTs (Table A) compared procalcitonin guidance with the use of clinical … with antibiotic stewardship programs • Antibiotic stewardship programs compared with and without … procalcitonin guidance • Procalcitonin guidance compared with implementation of guidelines 13
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
    August 01, 2012 - Different prescriptions of SMBP should be compared in trials examining SMBP adherence and BP control … No trials compared different SMBP devices or provided evidence on the relationship between BP control … No trials compared different SMBP devices or provided evidence on the relationship between BP control … SMBP can be compared against usual care by nesting within the medical therapy arm or by using a 2x2 … In looking across studies that compared SMBP alone against usual care, and studies that compared SMBP
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - lidocaine-alone group had improved pain-related functional disability and leg pain intensity when compared … Injection of glucocorticoids plus lidocaine produced minimal or no short-term (6 weeks) benefit when compared
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
    September 15, 2008 - The limited data available did not support a significant benefit of fundoplication compared with medical
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - will be at least as likely to reflect flaws in the study design as the true difference between the compared … Treatment strategies to be compared within the general categories: For example, support surfaces would … be compared with one another, and wound dressings would be compared with one another.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
    April 01, 2013 - weight control and related physical health outcomes (e.g., health-related quality of life, mortality) compared … control (26% of comparisons), followed by neurologics (13%), and psychotropics or antihistamines compared … Relatively few studies compared two active interventions. … • There was no advantage in favor of nizatidine compared with placebo for the management of weight … We found moderate SOE that behavioral interventions are associated with small decreases in weight compared
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
    July 08, 2014 - studies (pregnant women who did not take an antidepressant, and with unknown depression status in compared … The Gartlehner review certainly establishes the comparative effectiveness of antidepressants compared … to each other, although work by Turner reveals serious reporting bias in antidepressant studies compared … (especially compared to the next statement on duration of treatment— much more clear) Changed to: … Analysis of women with depression who received an SSRI compared with a population of pregnant women

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