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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
    May 01, 2013 - KQ 4: What are the comparative benefits of screening for postpartum depression when compared with no … Three studies directly compared organized screening with no screening or “usual care.” … There were few direct comparisons between screening instruments, and the studies that directly compared … There were only a few studies that directly compared screening with any instrument with no screening … This estimate could be compared with the estimated number of unwanted screening outcomes resulting
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_surveillance.pdf
    January 01, 2013 - May, 2013 Key Findings: - A large number of relatively small new studies were identified that compared … AMT had no major complications compared with trabeculectomy with no anti-metabolites in a prospective … Efficacy and safety of preservative-free latanoprost eyedrops, compared with BAK-preserved latanoprost … Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine … Compared with timolol Mt, latanoprost/timolol FC led to a greater IOP reduction than bimatoprost/timolol
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
    June 01, 2013 - years have led to improved outcomes, overall 5-year survival is only 42 percent for ovarian cancer compared … mortality rate in women with ovarian cancer is largely attributed to the later stage at presentation compared … due to the presence of a BRCA1 or BRCA2 mutation, and there are ongoing trials of its effectiveness compared … Results of a qualitative analysis of additional studies that directly compared progestin generations … suggested that the risk of VTE is highest for third-generation progestins compared with levonorgestrel
  4. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
    February 25, 2016 - Key Question 1 addresses the utility of the tGCS compared with the mGCS for predicting clinical outcomes … Key Question 1 does not directly assess the utility of the tGCS compared with the mGCS for predicting … Key Question 2 addresses the impact of the tGCS compared with the mGCS on rates of over- or under-triage … Key Question 3 addresses the impact of the tGCS compared with the mCGS on clinical outcomes. … Key Question 4 addresses the reliability and ease of use of the tGCS compared with the mGCS.
  5. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
    October 01, 2007 - ventricular function because it has been previously shown in randomized trials to improve survival compared … disease and angiographically proven single or multi- vessel disease, what is the effectiveness of PCI compared … Patients aged 65 years and older had lower long-term survival compared with younger patients. … Among the 62 patients with diabetes in the RITA trial, however, only 2 of the 29 PCI patients died, compared … A randomized study of coronary angioplasty compared with bypass surgery in patients with symptomatic
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
    February 13, 2012 - ultrasound were performed, yet the results are presented as though all imaging tools, including US, were compared … Anderson Cancer Center13 that compared length of survival of metastatic breast cancer patients treated … after their diagnosis with metastatic disease, 40 percent of these patients were still alive, as compared … results does not make this clear and leaves one with the assumption that each of the tools can be compared … to each other (eg, ultrasound compared to MRI) regarding their addition to mammography alone The
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
    January 01, 2010 - What are the benefits and harms of rhythm control compared to rate control (including newer agents)? … The evolution of newer anticoagulation agents as well as the risks and benefits when compared to older
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
    June 01, 2013 - Four different screening strategies were evaluated: (1) universal screening compared with no screening … ; (2) universal screening compared with targeted screening of selected patient populations; (3) targeted … screening of selected patient populations compared with no screening; and (4) expanded screening compared … ; (3) targeted screening of selected patient populations compared with no screening; and (4) expanded … If the design of these types of studies is improved, they may be a less- costly option compared with
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-c.xlsx
    January 01, 2024 - with 0.005), Recall (0.9676 compared with 0.878), and F-measures (0.2898 compared with 0.0356 in F3 … The use of full texts did not result in significant gains compared with title, abstract, keywords, and … The use of full texts did not result in significant gains compared with title, abstract, keywords, and … The use of full texts did not result in significant gains compared with title, abstract, keywords, and … The use of full texts did not result in significant gains compared with title, abstract, keywords, and
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
    August 01, 2012 - The following four treatment modalities were compared: intensity-modulated radiotherapy (IMRT), 3-dimentional … The sample size of the studies ranged from 336 to 1613. 9 The included studies compared conventional … original CER finding, IMRT was associated with fewer cases of xerostomia at 6, 12, 24, and 36 months compared … incidence of other adverse events i.e. dermatitis 7 and dysphagia 6 favored IMRT treatment groups compared … to 3DCRT, but in another study the rate of mucositis was higher in IMRT compared to 2DRT.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
    December 01, 2014 - We sought direct evidence for one intervention compared with another, with or without chemotherapy … Comparators For comparators (Key Questions 1–4) all therapies were compared with each other as part … Thus, 3DCRT and IMRT were compared in 14 reports that contained unique data, including Rathod et al … .’s RCT.15 One study compared 3DCRT and SBRT;16 none compared IMRT and SBRT. … The major advantage of these interventions compared with traditional wide-field 2DRT is the ability to
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
    March 01, 2012 - ramipril (two studies) and no significant difference compared to the ARB losartan (one study). … The impact of ACEI/ARB/DRI alone compared to ACEI/ARB/DRI in combination with a diuretic 11 … Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis. … J Renin Angiotensin Aldosterone Syst 12 (Jun) 102-12 10 The impact of ACE-I/ARB/DRI alone compared … Am J Med 122 (Mar) 290-300 12 Studies of cardiovascular and cerebrovascular events compared across
  13. Insomnia Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
    December 01, 2015 - Another trial compared mean change in PSQI and showed consistent results. … Results for adverse effects were mixed, with few differences compared with placebo. … ● In older adults, improvement in ISI scores favored doxepin 1–6 mg compared with placebo. … ● Four small trials compared CBT-I versus nonbenzodiazepine hypnotics or benzodiazepines. … In older adults, improvement in ISI scores favored doxepin 1–6 mg compared with placebo.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/psychiatric-readmissions_research-protocol.pdf
    December 31, 2014 - Different LOS compared with each other b. … Different transition support services compared with each other b. … Transition support services compared with usual care c. … Transitions support services compared with one or more variants of the three intervention management … Different alternatives to hospitalization compared with each other b.
  15. S23 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
    October 01, 2007 - higher odds of stroke; use as appetite suppressants was associated with 16.6 times higher odds of stroke compared … Brass, put his estimate for the chance of hemorrhagic stroke as “perhaps 1 in 500,000” users.17 When compared … systematic review has shown that HRT is associated with a 29% higher risk of stroke (a factor of 1.29) compared … and Harms © 2007 Lippincott Williams & Wilkins S25 cumulative risk of stroke and death by 24.2% compared … data is not consistently presented in the article to judge about benefits and harms of Aggrenox when compared
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
    November 16, 2010 - program for open-angle glaucoma lead to less visual impairment (as defined in the ICD-9-CM8) when compared … screening-based program for open-angle glaucoma lead to improvements in patient- reported outcomes when compared … a screening-based program for open-angle glaucoma lead to reductions in intraocular pressure when compared … including measures among those administering the test as well as those being tested—will also be compared … Key Question 6: The proportion of participants experiencing the following adverse events will be compared
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
    January 27, 2012 - For KQ 3 (harms), double-blind RCTs and recent systematic reviews that compared one of the medications … Evidence from well-controlled trials does not adequately support the efficacy of disulfiram comparedCompared with placebo, patients treated with acamprosate had a higher risk of anxiety, diarrhea, and … First, a nested sequence of three RCTs based in the United States compared naltrexone plus “primary … Patients with at least 1 G allele may be more likely to respond to naltrexone compared with patients
  18. effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
    January 01, 2013 - Covariate Selection for Observational Comparative Effectiveness Research Considerations for Statistical Analysis in Observational Comparative Effectiveness Research Prepared for: Agency for Healthcare Research and Quality (AHRQ) www.ahrq.gov Considerations for Statistical Analysis in Observational Comparative Effe…
  19. effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
    January 01, 2013 - Covariate Selection for Observational Comparative Effectiveness Research Covariate Selection for Observational Comparative Effectiveness Research Prepared for: Agency for Healthcare Research and Quality (AHRQ) www.ahrq.gov Covariate Selection for Observational Comparative Effectiveness Research This slide set is b…
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
    August 10, 2022 - guideline did not explicitly address the benefits and harms of therapies used in addition to EBRT compared … e.g., , surgery, radionuclide therapy, bisphosphonate therapy, ablation kyphoplasty/vertebroplasty) compared … Studies with the least risk of bias will be summarized separately and compared with summarized results … ., surgery, radionuclide therapy, bisphosphonate therapy, ablation kyphoplasty/ vertebroplasty) compared … radionuclide therapy, bisphosphonate therapy, ablation kyphoplasty/ vertebroplasty) compared with

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