-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
August 24, 2012 - the
differences between currently discussed policy/payment models (ACOs,
cross-continuum efforts) compared … Affiliation
Section Comment Response
Peer Reviewer
#6
Results Bundled payment is virtually always compared … These results should be compared to survey results from
persons not in bundled payment arrangements. … process-related
performance measures, such as the Surgical Care Improvement Project
measures, when compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - No study
compared effects of different imaging modalities or
strategies on diagnostic thinking or on … However, two studies that directly compared
sensitivity of US without contrast and CT reported lower … Other factors US Low In 2 studies that directly compared US with vs. without contrast, there was no … One study that
directly compared use of Doppler vs. no Doppler showed no clear effect on
estimates … PET Low In 1 study that directly compared sensitivity of PET vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_surveillance.pdf
January 01, 2013 - May, 2013
Key Findings:
- A large number of relatively small new studies were
identified that compared … AMT had no major
complications compared
with trabeculectomy with
no anti-metabolites in a
prospective … Efficacy and safety of preservative-free
latanoprost eyedrops, compared with BAK-preserved latanoprost … Twenty-four hour efficacy with the
dorzolamide/timolol-fixed combination compared with the brimonidine … Compared with timolol Mt,
latanoprost/timolol FC led to a greater
IOP reduction than bimatoprost/timolol
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - KQ 4: What are the comparative benefits of screening for
postpartum depression when compared with no … Three studies directly compared organized screening
with no screening or “usual care.” … There were few direct comparisons between screening
instruments, and the studies that directly compared … There
were only a few studies that directly compared screening
with any instrument with no screening … This estimate could
be compared with the estimated number of unwanted
screening outcomes resulting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - years
have led to improved outcomes, overall 5-year
survival is only 42 percent for ovarian cancer
compared … mortality rate in women with ovarian
cancer is largely attributed to the later stage
at presentation compared … due to the presence of a BRCA1 or BRCA2 mutation, and
there are ongoing trials of its effectiveness compared … Results of
a qualitative analysis of additional studies that directly
compared progestin generations … suggested that the risk of
VTE is highest for third-generation progestins compared
with levonorgestrel
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - and colleagues announced results from a 56-week phase III trial (COR-I)
evaluating NB32 and NB16 compared … patients and 40.6% of lorcaserin 10 mg once daily
(QD) patients achieved at least 5% weight loss, compared … of obesity
patients and 25.5% of lorcaserin 10 mg QD patients achieved at least 10% weight loss, compared … and 6.7% with top-dose phentermine/topiramate and low-dose
phentermine/topiramate, respectively, compared … Mean weight loss with liraglutide 1.2
to 3.0 mg was 4.8 kg, 5.5 kg, 6.3 kg, and 7.2 kg compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
February 25, 2016 - Key Question 1 addresses the utility of the tGCS compared with the mGCS for predicting
clinical outcomes … Key Question 1 does not directly assess the utility of the tGCS compared with the
mGCS for predicting … Key Question 2 addresses
the impact of the tGCS compared with the mGCS on rates of over- or under-triage … Key Question 3 addresses
the impact of the tGCS compared with the mCGS on clinical outcomes. … Key Question 4
addresses the reliability and ease of use of the tGCS compared with the mGCS.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
October 01, 2007 - ventricular function because it has
been previously shown in randomized trials to improve
survival compared … disease and angiographically proven single or multi-
vessel disease, what is the effectiveness of PCI
compared … Patients
aged 65 years and older had lower long-term survival
compared with younger patients. … Among the 62 patients with diabetes in the
RITA trial, however, only 2 of the 29 PCI patients died,
compared … A randomized study of coronary angioplasty compared with bypass surgery in
patients with symptomatic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
January 01, 2010 - What are the benefits and harms of rhythm control compared to rate control
(including newer agents)? … The
evolution of newer anticoagulation agents as well as the risks and benefits when compared to older
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
June 01, 2013 - Four different screening strategies were evaluated: (1) universal screening compared with no
screening … ; (2) universal screening compared with targeted screening of selected patient
populations; (3) targeted … screening of selected patient populations compared with no screening;
and (4) expanded screening compared … ; (3) targeted screening of selected patient populations compared with no screening;
and (4) expanded … If the design of these types of studies is improved, they may be a less-
costly option compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - The following four treatment modalities were compared:
intensity-modulated radiotherapy (IMRT), 3-dimentional … The sample size of the studies ranged from 336 to 1613. 9 The
included studies compared conventional … original CER finding, IMRT was associated with fewer cases of
xerostomia at 6, 12, 24, and 36 months compared … incidence of other adverse events i.e. dermatitis 7 and dysphagia 6
favored IMRT treatment groups compared … to
3DCRT, but in
another study the
rate of mucositis
was higher in IMRT
compared to 2DRT.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
December 01, 2014 - We sought direct evidence for one
intervention compared with another, with or without
chemotherapy … Comparators
For comparators (Key Questions 1–4) all therapies were
compared with each other as part … Thus, 3DCRT and IMRT were compared in
14 reports that contained unique data, including Rathod
et al … .’s RCT.15 One study compared 3DCRT and SBRT;16
none compared IMRT and SBRT. … The major advantage of these interventions compared with traditional wide-field 2DRT is the ability to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
March 01, 2012 - ramipril (two studies) and no significant difference
compared to the ARB losartan (one study). … The impact of ACEI/ARB/DRI alone compared to ACEI/ARB/DRI in combination
with a diuretic
11 … Efficacy and tolerability of nebivolol compared with other
antihypertensive drugs: a meta-analysis. … J Renin Angiotensin
Aldosterone Syst 12 (Jun) 102-12
10 The impact of ACE-I/ARB/DRI alone compared … Am J Med 122 (Mar) 290-300
12 Studies of cardiovascular and cerebrovascular events compared across
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
December 01, 2015 - Another trial compared
mean change in PSQI and showed consistent results. … Results for adverse effects were mixed, with few
differences compared with placebo. … ● In older adults, improvement in ISI scores favored
doxepin 1–6 mg compared with placebo. … ● Four small trials compared CBT-I versus
nonbenzodiazepine hypnotics or benzodiazepines. … In older adults, improvement
in ISI scores favored doxepin 1–6 mg compared with
placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/psychiatric-readmissions_research-protocol.pdf
December 31, 2014 - Different LOS compared with each other
b. … Different transition support services compared with each
other
b. … Transition support services compared with usual care
c. … Transitions support services compared with one or more
variants of the three intervention management … Different alternatives to hospitalization compared with each
other
b.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - program for open-angle glaucoma lead to less visual impairment (as
defined in the ICD-9-CM8) when compared … screening-based program for open-angle glaucoma lead to improvements in patient-
reported outcomes when compared … a screening-based program for open-angle glaucoma lead to reductions in intraocular
pressure when compared … including measures among those administering the test as well
as those being tested—will also be compared … Key Question 6:
The proportion of participants experiencing the following adverse events will be compared
-
effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - higher odds of
stroke; use as appetite suppressants was associated with 16.6
times higher odds of stroke compared … Brass, put his estimate for the chance of hemorrhagic stroke as
“perhaps 1 in 500,000” users.17
When compared … systematic
review has shown that HRT is associated with a 29% higher risk
of stroke (a factor of 1.29) compared … and Harms
© 2007 Lippincott Williams & Wilkins S25
cumulative risk of stroke and death by 24.2% compared … data is not consistently presented in the
article to judge about benefits and harms of Aggrenox when
compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - For KQ 3 (harms), double-blind RCTs and recent
systematic reviews that compared one of the medications … Evidence from well-controlled trials does
not adequately support the efficacy of disulfiram compared … Compared with placebo, patients treated
with acamprosate had a higher risk of anxiety, diarrhea,
and … First, a nested sequence of three RCTs based in the
United States compared naltrexone plus “primary … Patients with at least 1 G allele may be
more likely to respond to naltrexone compared with patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
January 01, 2010 - triage of when a woman in labor should
leave for the hospital did not reduce use of cesarean when
compared … A midwife-led unit for
birth did not reduce use of cesarean when compared
with a normal unit and special … , reported a threefold reduction
in cesareans among women who received intermittent
epidural (5%) compared … A larger good-quality study that compared
high- versus low-dose epidural reported significantly
fewer … Head-to-Head Comparisons of Strategies
All studies compared the novel strategy with usual care
or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - Added “Twenty-three percent of
trials directly compared different
treatment strategies.” … Studies that compared
Crohn’s disease patients to
patients without inflammatory
bowel disease were … Per PRECiSE 1, IBDQ response was defined as an increase of at least 16 points in total
score compared … Notably, the baseline CDEIS was higher in the infliximab group (13.0) compared to placebo
(8.4). … Relative
benefits versus relative risks are not compared or reviewed.