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effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - There was
insufficient evidence of differences between all tests
that were not directly compared. … There was insufficient evidence of
differences between all tests that were not directly
compared. … a nonstandard intervention with
placebo.87 All of the 13 prevention studies compared the
nonstandard … However, the strength of the evidence
is low due to the number of studies that have directly
compared … Gene detection tests versus Low to moderate • Four studies compared at least one toxin gene detection
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - Two RCTs compared frenotomy to sham surgery,11, 13 one
to usual care,10 and one to intensive lactation … each order of intervention (i.e., frenotomy and sham).14
Similarly, the retrospective cohort study compared … better parent-reported ability to clean teeth with tongue,
lick outside of lips, and eat ice cream compared … Maternally reported breastfeeding
effectiveness was significantly improved in the treated
group compared … One poor-quality RCT reported improved articulation
in patients treated with Z-frenuloplasty compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
April 01, 2012 - Does
trabeculectomy potentially reduce the risk of vision loss compared
with all medical interventions … Trabeculectomy was not compared to particular agents
across (or frequently within) these studies so … This can be compared with a
report by Torrance and Feeny of utility values of 0.90 for mild
angina, … Treatment of OHT and OAG was found to lead to better
preservation of VF compared with observation. … Trabeculectomy
showed better preservation of VF compared with the other two
modalities.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - • Comparators: Studies included for assessing
efficacy or effectiveness were those that compared … No studies compared the effect of physical
activity to that of other interventions. … • The evidence is insufficient, from three head-to-
head trials of bisphosphonates compared to calcium … • Evidence is moderate (one large RCT) that,
compared to using alendronate for 5 years followed
by … Pooled analysis also showed alendronate users to be at
an increased risk for mild GI events compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - Methods: We compared the number-needed-to-treat (NNT) and number-needed-to-harm (NNH)
approach and the … When we weighted outcomes equally in a
sensitivity analysis, the harm from aspirin was greater compared … We assessed the use of low dose (75-100
mg) aspirin compared with placebo using a time horizon of 10 … We compared the results using the alternative relative weights to the results
incorporating relative … Compared with the baseline incidence rates in Table 1, the trial-based incidence rates compared
12
-
effectivehealthcare.ahrq.gov/products/heart-failure-therapies/abstract
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - When compared with the lowest quintile, the
highest quintile was associated with a rate ratio of 3.0 … In contrast, use of etanercept alone was less
likely to result in switching, compared with use of meth … Compared with methotrexate and after adjustment
for measured confounders, new users of sulfasalazine … Treatment of active rheumatoid
arthritis with leflunomide compared with placebo and methotrexate. … Survival and effectiveness of
leflunomide compared with methotrexate and sulfasalazine in rheuma-
toid
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
January 31, 2023 - While it may be standard format, the use of the word “harms” when referring to PBI
compared to WBI gives … Statement about “significantly fewer adverse events (AEs) with PBI compared with
WBI with no apparent … there may be more evidence of reduced late toxicity if both the same hypo
fractionated regimen is compared … In
the report,
we describe
comparison of
twice daily
treatment in
10 fractions
compared to
5 … E.g. large PBI volume in IMPORT Low
showed decreased toxicity compared with a hypofractionated WBRT
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - These
studies compared the use of long tolerated
innovator antiepileptic medication with short-term … There was no
statistically significant difference in women
compared with men when switching back to … Younger patients were more likely to require a
switchback to innovator medication compared
with older … These studies compared the use of long tolerated
innovator antiepileptic medication with short-term … There was no statistically
significant difference in women compared with men when
switching back to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - These
studies compared the use of long tolerated
innovator antiepileptic medication with short-term … There was no
statistically significant difference in women
compared with men when switching back to … Younger patients were more likely to require a
switchback to innovator medication compared
with older … These studies compared the use of long tolerated
innovator antiepileptic medication with short-term … There was no statistically
significant difference in women compared with men when
switching back to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
April 01, 2012 - Outcomes would be assessed and compared among those
who were identified via a screening based program … Outcomes would be assessed and compared among those
who were identified via a screening based program … Quality
of life and other patient reported outcomes would be
assessed and compared among those who … Outcomes would be assessed and compared among those
who were identified via a screening based program … The draft report did not discuss studies that examined
identifying early disease compared with late
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - collected the following information for each
report: title, year of publication, types of interventions compared … in factors other than the intervention of interest across the time periods
single group of patients compared … As an example, a time-series
study based on employment records merged with prescription records compared … must be assumed that the intervention of interest presents the only
change across the time periods compared … though the two arm studies required a 2–4 fold increased sample size).
24
A third
simulation study compared
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
April 01, 2013 - The CER analyses revealed that PCA3 had improved diagnostic accuracy compared with
tPSA in identifying … Note: For link B, PCA3 shows increased diagnostic accuracy compared with tPSA (low strength of evidence … What is the comparative
effectiveness of PCA3 compared
with the 2 commonly used add-on
tests of fPSA … Note: For link B, PCA3 shows increased diagnostic accuracy compared to tPSA (low strength of evidence … A small number of articles described PCA3 compared to percent-free PSA or to
nomograms; however, the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - limited evidence
from well-controlled trials does not adequately support the efficacy of disulfiram
compared … limited evidence from well-controlled trials does not adequately support
the efficacy of disulfiram compared … Compared with placebo, study participants treated with acamprosate were more
likely to experience anxiety … Subgroups: We did not find any convincing evidence that any
medication is more or less effective (compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-executive-summary.pdf
April 01, 2025 - positive screen), and appropriate prescribing for
mental health conditions (initiating treatment) compared … approaches on patient outcomes was limited to clinician support, which did not
improve risk behavior compared … Findings of low or very low evidence suggest that compared with minimal or no
implementation, various … moderate strength, clinician support did not reduce risk
behaviors despite an increase in counseling compared … at increased risk of
alcohol and substance use when delivered with clinician support and reminders compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_executive.pdf
January 01, 2020 - Excluded studies if a study compared a strategy of interest with only a strategy not of interest. … during exercise after being instructed how to perform
the monitoring during a routine clinic visit compared … A randomized
trial provided fruits and vegetables to group homes of
people with schizophrenia compared … Although these interventions
did not uniformly result in weight maintenance compared
with control or … Different degrees of intensity of the strategies should be
compared.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
December 01, 2021 - All of the trials compared a mask versus
no mask. … compared a mask versus hand hygiene17,18,20 and two trials compared a mask
plus hand sanitizer versus … an N95 versus surgical mask and one28
compared a surgical versus cloth mask. … A cluster
randomised trial of cloth masks compared with
medical masks in healthcare workers. … A
cluster randomised trial of cloth masks
compared with medical masks in healthcare
workers.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
March 29, 2013 - How do pharmacological treatments affect maternal and child* outcomes when
compared with placebo or … How do pharmacological treatments affect maternal and child outcomes when
compared with each other ( … How do pharmacological treatments affect maternal and child* outcomes when
compared with placebo or … How do pharmacological treatments affect maternal and child outcomes when
compared with each other ( … • The drugs listed above in Table 1 when compared with each other.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
January 01, 2007 - superior to placebo in one study for each
drug, but data are conflicting in two other studies
that compared … The one available study of ziprasidone showed
variable effectiveness compared to placebo. … Both
drugs were associated with an increase in EPS
(OR: 2.53 and 2.82, respectively) compared to
placebo … Ziprasidone was associated with an increase in
EPS when compared to placebo in a pooled
analysis of adults … Compared to placebo, all atypicals were associated
with sedation in multiple pooled analyses for all
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - Clinical reviews have
compared the safety of only a few drugs.20,21
Scope
Our review focuses on the … What are the harms from preventive pharmacologic
treatments when compared with placebo or no active … What are the harms from preventive pharmacologic
treatments when compared with active pharmacologic … Most trials examined a monotherapy with one
active agent compared with placebo or another drug. … Presence of Aura
No trials directly compared drug effects in patients with
and without aura.