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effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - The third trial compared TURP to clean intermittent self-catheterization but did not evaluate
any of … The fourth study compared
bethanechol/prostaglandin (BC/PGE2) to placebo. … Three eligible RCTs compared treatments for CUR in men with bladder outlet
obstruction secondary to … All three trials compared surgery (transurethral resection of the prostate or prostate enucleation) … The fourth study compared
bethanechol/prostaglandin (BC/PGE2) to placebo.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
March 31, 2010 - America’s children.1-3
Overweight children and adolescents
are at greater risk for health problems
compared … focus in this report on the comparative
effectiveness of interventions; thus, outcomes need to be
compared … We compared the effects of the interventions on outcomes
related to weight or body composition (e.g. … All of them
reported statistically significant beneficial effects of the
intervention compared with … Two of the RCTs detected a statistically significant
beneficial effect of the intervention compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - would allow users of comparative effectiveness reviews to make judgments about the treatments being compared … interval so wide that it does not rule out the superiority or inferiority of either treatment being compared … transparency, as yet no empirical evidence supports the superiority of a particular point system when compared … believe that for certain outcomes, such as harms, observational studies have less risk of bias when compared
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effectivehealthcare.ahrq.gov/sites/default/files/reporting.ppt
September 01, 2009 - Example 1:
[B]enefits of chondroitin were smaller in trials with adequate concealment of allocation compared … with unclear concealment (P for interaction = 0.050), in trials with an intention-to-treat analysis compared … with those that had excluded patients from the analysis (P for interaction = 0.017), and in large compared … Discussion: Summary of Evidence
Example:
Compared with men who used watchful waiting , men with clinically
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - , for example two different
conformal RT methods or RFA compared to a conformal RT method … ○ For KQ 3, combinations may be considered, for example endobronchial debridement plus
a stent, compared … to debridement alone; or, combination of 2D-RT with BT compared to
RT alone … Endobronchial debridement and stents
Comparators
KQs 1 and 2
○ Interventions will be compared … KQ 3
○ Interventions will be compared to each other as appropriate and noted above.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - Most studies have investigated differences in supervised
exercise training when compared with standard … More recently,
supervised exercise training has also been compared to endovascular revascularization … The 2008 Cochrane review by Watson et
al.22 identified only two RCTs that compared walking outcomes … A review by Wilson26 identified an additional four RCTs conducted between 1990
and 2008 that compared … While
improved clinical outcomes have been reported with angioplasty and stenting when compared to
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - xerostomia was reduced and QoL domains
related to xerostomia were improved in patients treated with IMRT compared … greater importance in patients identified
with HPV as the causative agent of head and neck cancer, compared … We will seek direct evidence for one
intervention compared to another, with or without chemotherapy … Thus, we will include studies in which a RT method
was compared to a different method, for example with … In a
qualitative synthesis of this hypothetical body of evidence, insufficient size (as
compared
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - Average weight loss at week 108 was -9.3% and -
10.5%, respectively, for the mid- and top-dose as compared … and 6.7% with top-dose phentermine/topiramate and low-dose
phentermine/topiramate, respectively, compared … mean percent weight loss at week 56 was 10.0% and 5.1% for the top and low
dose, respectively, as compared … 48.9 kg/m
2
underwent EndoBarrier
implantation in conjunction with dietary restriction and were compared … second European trial, EndoBarrier implantation was attempted on 27 patients whose
outcomes were compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_executive.pdf
January 01, 2013 - Comparators
In most studies, CM is compared with usual care
(i.e., care without a CM component). … When a study compared
two or more different types of CM, then the comparator
was the alternative type … Nearly all of the clinical trials of CM programs compared
a single type of program with a usual care … There
were very few trials that directly compared more than
one model of CM. … Some published trials14 have used
existing tools, but no studies have compared tools or
rigorously
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - Meta-analyses have examined individual medications
compared to placebo but few have compared medications … These sensitivity analyses will be compared to our analyses of
moderate-to-severe Crohn’s disease. … Crohn’s disease, we will include randomized controlled trials (RCTs) of the
medications of interest compared … a Crohn’s disease medication of interest (see Table 1) or
combination of medications of interest compared … We will exclude studies that compared a medication of interest to a medication not of
interest (such
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
March 01, 2009 - Binary variables were compared across interventions using the Pearson Chi-square test. … Continuous and ordinal categorical variables were compared using the Wilcoxon rank
sum test. … The adjusted
hazard ratio for death or MI of DES-C compared with DES+C was 1.93 (95% CI of 1.05, … Compared to BMS patients (BMS+C and BMS-C),
DES+C patients had significant reductions in the outcomes … Compared to DES-C, patients with DES+C tended to have lower
mortality (Figure 4A) and had lower rates
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
November 24, 2014 - As an initial treatment choice, how effective are SGAs compared with
nonpharmacologic interventions? … treatment attempt,
what is the effectiveness of second-generation antidepressants (SGAs) monotherapy
compared … an initial
adequate trial with an SGA, what is the effectiveness of switching to a different SGA
compared … initial adequate trial
with an SGA, what is
the effectiveness of
switching to a different
SGA compared … nonpharmacologic
treatment
When we revised KQ2a,
we broadened the
management strategies
that could be compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - In this group, adjuvant chemotherapy may produce a small improvement in
overall survival when compared … What are the potential benefits and harms of this testing compared to current
practice?
e. … Was a reclassification analysis performed with risk stratification using GEP when
compared with that … Whether or not
data are available about the incremental information provided by GEP testing
when compared … , 2012
availability of data on the incremental information provided by GEP testing when
compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
July 31, 2012 - Thus, these reviews
establish the contribution of each technique when compared with not using any communication … Federal and State policymakers because they have
less direct impact on clinical decisionmaking when compared … approach with a combination of two or more communication techniques (e.g.,
tailoring and targeting) compared … a combination of two or more dissemination strategies (e.g.,
social marketing, academic detailing) compared … an intervention is expected to have the same effect in the
population in which it will be used as compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
March 10, 2010 - Angiotensin-
Converting Enzyme Inhibitor-Intolerant Patients with Cardiovascular
Disease (TRANSCEND) trial compared … Four of the seven studies included here
have less than 1 year follow (compared to 4-5 yearly in the … across indications to see if there is a statistically significant
difference in effect sizes for ACEs compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0368_11-08-2010.pdf
January 01, 2010 - The nominator is interested in an effectiveness review of
mindfulness-based stress programs compared
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
November 30, 2011 - is HCV genotype, with higher SVR rates
in patients with genotypes 2 or 3 (SVR of 70 to 80 percent) compared … based on the methods used for
randomization, allocation concealment, and blinding; the similarity of compared … results are at least as likely to
reflect flaws in the study design as the true difference between the compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - parameters and functional parameters.10
► Basic parameters are effect parameters that are directly compared … arms across
studies, thereby producing a pooled rate/mean outcome per arm.
► Estimates can then be compared … measures for the entire network.
► Loop-based approaches in which direct and indirect estimates are
compared
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-disorders-imaging_research-protocol.pdf
August 05, 2010 - rheumatologic, orthopedic and neurologic conditions, as it can better
delineate soft tissue structures compared … What are the postulated advantages and disadvantages of positional MRI testing
compared to contemporary … What additional equipment or technical
resources are needed in order to operate positional MRI, compared … What is the cost of imaging with positional MRI as compared to other imaging
alternatives?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - to the lack of adverse cardiac side effects with
this small daily dosage of terbutaline (3mg/day) compared … No group will look at these outcomes in SCT patients
compared to a control group and follow them long-term