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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
    March 01, 2013 - Question 1: Conclusion regarding biologic Disease- Modifying Antirheumatic Drug (DMARD) plus oral DMARD compared … - Key Question 2: Conclusion regarding biologic DMARD plus oral DMARD compared to either alone is … One expert did not know Conclusion regarding biologic DMARD plus oral DMARD compared to either … Two combo patients had serious AE compared to no one in MTX group. … Two combo patients had serious AE compared to no one in MTX group.
  2. effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
    November 01, 2020 - advanced cancer: • Airflow interventions (fans) were more effective for improving breathlessness compared … interventions incorporating all three intervention types were more effective for improving breathlessness compared … draw conclusions Pharmacological interventions: • Corticosteroids had lower rates of drowsiness compared … • Opioids had higher rates of constipation compared with steroids. … Nonpharmacological compared with pharmacological: The evidence was insufficient to draw any conclusions
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
    October 01, 2019 - • Titrated oxygen reduces mortality compared with high flow oxygen. … Whole body vibration training improved QoL compared with management without nonpharmacologic therapies … Titrated oxygen reduced mortality compared with high flow oxygen at the longest followup (low SOE). … Vitamin D supplementation improved quality of life compared with placebo (low SOE). … with telithromycin; and for higher rate of adverse events with imipenem plus cilastatin compared with
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - Five RCTs (n=1,227)13,16-19 and four observational studies (n=1,066)20-23 directly compared either a … L PASI 1 RCT13 1 OBS23 Adalimumab improves a patient’s PASI compared with methotrexate. … L Pain 1 RCT30 Adalimumab reduces a patient’s pain compared with methotrexate. … L Pruritus 1 RCT30 Adalimumab reduces a patient’s pruritus compared with methotrexate. … L PASI 1 RCT16 1 OBS21 Infliximab improves a patient’s PASI compared with methotrexate.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/use-telehealth-during-COVID-19-executive-summary.pdf
    January 01, 2023 - • Across a variety of conditions, telehealth produced similar clinical outcomes as compared with … medical conditions, those who received an initial telehealth visit had lower hospitalization rates compared … telehealth visit may have had better patient-reported outcomes and condition-specific clinical outcomes compared … We identified no studies that directly evaluated or compared implementation strategies, which was not … We found that, compared with in-person care, the use of telehealth may achieve comparable clinical or
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
    October 29, 2012 - What are the harms from nonpharmacological treatments when compared with each other? 6. … Darifenacin improved UI when compared to placebo in older women. … What are the harms from nonpharmacological treatments when compared with each other? 6. … Duloxetine Duloxetine did not resolve stress UI when compared to placebo (Table B). … Darifenacin improved UI when compared to placebo in older women.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - The study compared FFR (cutoff 0.8) or IVUS (4 mm2 derived minimal lumen area), and the use of FFR … • No studies compared the use of other intravascular diagnostic techniques besides FFR. … • No studies compared the use of other intravascular diagnostic techniques besides IVUS. … One compared the use of IVUS with angiography in patients who had a stand-alone DCA. … The other study compared the use of IVUS after PTCA with PTCA without IVUS.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
    May 01, 2023 - Pharmacological treatment of postpartum HDP: We found 17 RCTs that compared various pharmacological … Five RCTs compared oral antihypertensive treatments for persistent postpartum HTN. … with standard (24 hour) treatment, 15 RCTs compared different doses of MgSO4, 2 RCTs compared intramuscular … In six RCTs that enrolled patients with preeclampsia with severe features and compared lower versus … The colors do not provide unique information compared with the text and symbols.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - Antiplatelet drug was directly compared with placebo and VKA only; FEI was directly compared with FXaI … with aspirin and IPC; aspirin was directly compared with placebo; TB402 was directly compared with … Antiplatelet drug was directly compared with placebo only; FEI was directly compared with FXaI only … was directly compared with enoxaparin plus IPC only; and edoxaban plus VFP was directly compared with … compared with placebo.
  10. effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - Antiplatelet drug was directly compared with placebo and VKA only; FEI was directly compared with FXaI … with aspirin and IPC; aspirin was directly compared with placebo; TB402 was directly compared with … Antiplatelet drug was directly compared with placebo only; FEI was directly compared with FXaI only … was directly compared with enoxaparin plus IPC only; and edoxaban plus VFP was directly compared with … compared with placebo.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
    March 13, 2013 - In renal transplants, does two hour post administration cyclosporine or tacrolimus monitoring (C2) compared … transplants, have multidrug protocols to target lower tacrolimus levels [4-6 ng/dL C0] been effective [compared … multidrug protocols for CNI minimization (low dose, withdrawal, avoidance, replacement, conversion) compared … CNI minimization strategies compared with each other: In renal transplants, what is the effectiveness … of any CNI minimization strategy (low dose, withdrawal, avoidance, replacement, conversion) compared
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0745-141009.pdf
    September 03, 2014 - What is the safety and efficacy of treatment with uterine artery embolization compared with abdominal … guided focused ultrasonography compared … What is the safety and efficacy of laparoscopic myomectomy compared with abdominal hysterectomy for … What is the safety and efficacy of laparoscopic myomectomy compared with vaginal hysterectomy for treatment … What is the safety and efficacy of vaginal hysterectomy compared with abdominal hysterectomy for the
  13. effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
    April 01, 2020 - These included 25 of cholinesterase inhibitors versus placebo (n=9,476), 11 that compared different … different prescription drugs (n=454), and five that compared prescription drugs with supplements ( … Two trials compared different prescription drugs (n=414). … Few trials directly compared different drug treatments. … Antipsychotics and antidepressants should be directly compared for treatment of BPSD.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - Key Messages • BT along with standard medical management, compared to medical management alone, may … • BT along with standard medical management, compared to a similar procedure without the heat (sham … • Patients given BT and standard care compared with patients given the sham bronchoscopic procedure … • •Patients treated with BT and standard care had fewer emergency department (ED) visits comparedCompared with sham treatment, the intention-to-treat analysis in a single RCT suggests that BT had no
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
    April 01, 2025 - children aged 3-17), the prevalence of current disruptive behaviors/conduct problems was 7.0 percent (compared … therapy and nonstimulant therapy was associated with reduced disruptive behaviors in some children compared … with disruptive behaviors, what is the relative effectiveness of psychosocial interventions alone compared … Across age groups, most trials that compared active psychosocial interventions found no differences … Across age groups, studies that compared an enhanced treatment versus a standard treatment, generally
  16. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
    September 01, 2009 - Compared with higher dose statins and to one another, do combination regimens differ in benefits and … Statin plus another hypolipidemic drug combination therapy was compared with statin monotherapy. … However, no trials examined this outcome in a high-risk population and compared the combination to a … Insufficient evidence compared statin-niacin and statin-omega-3 combination with monotherapy in this … compared to statin monotherapy.
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
    September 01, 2008 - When compared with premixed human insulin, premixed insulin analogues may provide a glucose- lowering … In addition, compared with premixed human insulin preparations, premixed insulin analogues allow patients … Two studies that compared the effect of insulin lispro 50/50 and of long- acting insulin analogues on … When compared with long-acting insulin analogues, insulin aspart 70/30 was significantly more effective … No studies compared insulin lispro 50/50 with oral antidiabetic agents.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
    May 01, 2017 - surgery in children with persistent middle ear fluid or recurrent ear infections Key Messages • Compared … nonsurgical treatment, while one study compared early versus delayed TT in different settings. … Three RCTs compared TT placement with daily oral antibiotic prophylaxis. … Two of these studies included a comparison with placebo and the third compared TT placement with no … The odds ratio for nonswimming compared to no precautions was 1.52 (95% CI 0.71 to 3.25).
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
    January 01, 2017 - Key Messages • Tonsillectomy compared with watchful waiting can modestly improve sleep and reduce … One moderate risk of bias RCT compared tonsillectomy and CPAP. … Five RCTs and one nonrandomized trial compared coblation and cold dissection tonsillectomy. … , but few compared partial and total using the same surgical technique. … We found a reduced need for analgesia with NSAIDs compared with placebo.
  20. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - However, only a few studies directly compared these approaches and the total number of patients studied … The limited data available did not support a significant benefit of fundoplication compared with medical … Comparison of surgery with endoscopic procedures Of the three nonrandomized studies that compared an … When esomeprazole 40 mg was compared with omeprazole 20 mg, there was a significant difference in favor … Improvement of esophageal pH exposure compared with sham could not be demonstrated for Stretta™.

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