-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - Question 1: Conclusion regarding biologic Disease-
Modifying Antirheumatic Drug (DMARD) plus oral
DMARD compared … - Key Question 2: Conclusion regarding biologic DMARD
plus oral DMARD compared to either alone is … One expert did
not know
Conclusion
regarding biologic
DMARD plus oral
DMARD compared
to either … Two combo patients had serious
AE compared to no one in MTX
group. … Two
combo patients had
serious AE compared
to no one in MTX
group.
-
effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
November 01, 2020 - advanced cancer:
• Airflow interventions (fans) were more effective for improving breathlessness
compared … interventions incorporating all three intervention types were more
effective for improving breathlessness compared … draw conclusions
Pharmacological interventions:
• Corticosteroids had lower rates of drowsiness compared … • Opioids had higher rates of constipation compared with steroids. … Nonpharmacological compared with pharmacological:
The evidence was insufficient to draw any conclusions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - • Titrated oxygen reduces mortality compared with high flow
oxygen. … Whole body vibration training improved
QoL compared with management without
nonpharmacologic therapies … Titrated oxygen reduced mortality compared with
high flow oxygen at the longest followup (low
SOE). … Vitamin D supplementation improved quality of
life compared with placebo (low SOE). … with telithromycin; and for higher rate
of adverse events with imipenem plus cilastatin
compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - Five RCTs (n=1,227)13,16-19 and four observational
studies (n=1,066)20-23 directly compared either a … L
PASI 1 RCT13
1 OBS23
Adalimumab improves a patient’s PASI
compared with methotrexate. … L
Pain 1 RCT30 Adalimumab reduces a patient’s pain
compared with methotrexate. … L
Pruritus 1 RCT30 Adalimumab reduces a patient’s pruritus
compared with methotrexate. … L
PASI 1 RCT16
1 OBS21
Infliximab improves a patient’s PASI
compared with methotrexate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/use-telehealth-during-COVID-19-executive-summary.pdf
January 01, 2023 - • Across a variety of conditions, telehealth produced similar clinical outcomes as
compared with … medical conditions, those who received an initial
telehealth visit had lower hospitalization rates compared … telehealth visit may have had better patient-reported outcomes and
condition-specific clinical outcomes compared … We identified no studies that directly evaluated or compared
implementation strategies, which was not … We found that,
compared with in-person care, the use of telehealth may achieve comparable clinical or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - What are the harms from nonpharmacological treatments when compared with each
other?
6. … Darifenacin improved UI when
compared to placebo in older women. … What are the harms from nonpharmacological treatments when compared with each other?
6. … Duloxetine
Duloxetine did not resolve stress UI when compared to
placebo (Table B). … Darifenacin improved UI when compared to placebo
in older women.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - The
study compared FFR (cutoff 0.8) or IVUS (4 mm2 derived
minimal lumen area), and the use of FFR … • No studies compared the use of other intravascular diagnostic
techniques besides FFR. … • No studies compared the use of other intravascular diagnostic
techniques besides IVUS. … One
compared the use of IVUS with angiography in patients who had a
stand-alone DCA. … The other
study compared the use of IVUS after PTCA with PTCA without
IVUS.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - Pharmacological treatment of postpartum HDP: We found 17 RCTs that
compared various pharmacological … Five RCTs compared oral antihypertensive
treatments for persistent postpartum HTN. … with standard (24 hour) treatment, 15 RCTs
compared different doses of MgSO4, 2 RCTs compared intramuscular … In six RCTs that enrolled patients with preeclampsia with severe features and
compared lower versus … The colors do not provide unique
information compared with the text and symbols.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Antiplatelet drug was directly compared with placebo and
VKA only; FEI was directly compared with FXaI … with aspirin and IPC; aspirin was
directly compared with placebo; TB402 was directly
compared with … Antiplatelet drug was directly compared
with placebo only; FEI was directly compared with FXaI
only … was directly compared with enoxaparin plus IPC only; and
edoxaban plus VFP was directly compared with … compared with placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Antiplatelet drug was directly compared with placebo and
VKA only; FEI was directly compared with FXaI … with aspirin and IPC; aspirin was
directly compared with placebo; TB402 was directly
compared with … Antiplatelet drug was directly compared
with placebo only; FEI was directly compared with FXaI
only … was directly compared with enoxaparin plus IPC only; and
edoxaban plus VFP was directly compared with … compared with placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
March 13, 2013 - In renal
transplants, does two hour post administration cyclosporine or tacrolimus monitoring
(C2) compared … transplants, have multidrug protocols to target lower tacrolimus levels [4-6 ng/dL C0]
been effective [compared … multidrug protocols for CNI minimization (low
dose, withdrawal, avoidance, replacement, conversion) compared … CNI minimization strategies compared with each other: In renal transplants, what
is the effectiveness … of any CNI minimization strategy (low dose, withdrawal, avoidance,
replacement, conversion) compared
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0745-141009.pdf
September 03, 2014 - What is the safety and efficacy of treatment with uterine artery embolization
compared with abdominal … guided focused ultrasonography compared … What is the safety and efficacy of laparoscopic myomectomy compared with
abdominal hysterectomy for … What is the safety and efficacy of laparoscopic myomectomy compared with vaginal
hysterectomy for treatment … What is the safety and efficacy of vaginal hysterectomy compared with abdominal
hysterectomy for the
-
effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
April 01, 2020 - These
included 25 of cholinesterase inhibitors versus
placebo (n=9,476), 11 that compared different … different prescription drugs (n=454),
and five that compared prescription drugs with
supplements ( … Two trials compared different
prescription drugs (n=414). … Few trials directly compared
different drug treatments. … Antipsychotics and antidepressants should be
directly compared for treatment of BPSD.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - Key Messages
• BT along with standard medical
management, compared to medical
management alone, may … • BT along with standard medical
management, compared to a similar
procedure without the heat (sham … • Patients given BT and standard care compared with
patients given the sham bronchoscopic procedure … • •Patients treated with BT and standard care had fewer
emergency department (ED) visits compared … Compared with sham treatment, the intention-to-treat
analysis in a single RCT suggests that BT had no
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
April 01, 2025 - children aged 3-17), the prevalence of
current disruptive behaviors/conduct problems was 7.0 percent (compared … therapy and nonstimulant therapy was
associated with reduced disruptive behaviors in some children compared … with disruptive
behaviors, what is the relative effectiveness of psychosocial
interventions alone compared … Across age groups, most trials that compared active
psychosocial interventions found no differences … Across age
groups, studies that compared an enhanced treatment versus a standard treatment,
generally
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - Compared with higher dose statins
and to one another, do combination regimens differ
in benefits and … Statin plus another hypolipidemic drug combination
therapy was compared with statin monotherapy. … However, no
trials examined this outcome in a high-risk population
and compared the combination to a … Insufficient evidence compared statin-niacin
and statin-omega-3 combination with monotherapy in
this … compared to statin
monotherapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - When compared with premixed human insulin,
premixed insulin analogues may provide a glucose-
lowering … In addition, compared with
premixed human insulin preparations, premixed insulin
analogues allow patients … Two studies that
compared the effect of insulin lispro 50/50 and of long-
acting insulin analogues on … When compared with
long-acting insulin analogues, insulin aspart 70/30 was
significantly more effective … No
studies compared insulin lispro 50/50 with oral
antidiabetic agents.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - surgery in
children with persistent middle ear
fluid or recurrent ear infections
Key Messages
• Compared … nonsurgical treatment, while one study compared
early versus delayed TT in different settings. … Three RCTs compared TT
placement with daily oral antibiotic prophylaxis. … Two of
these studies included a comparison with placebo and
the third compared TT placement with no … The odds
ratio for nonswimming compared to no precautions was
1.52 (95% CI 0.71 to 3.25).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - Key Messages
• Tonsillectomy compared with
watchful waiting can modestly
improve sleep and reduce … One moderate risk of bias RCT compared tonsillectomy
and CPAP. … Five RCTs and one nonrandomized
trial compared coblation and cold dissection tonsillectomy. … ,
but few compared partial and total using the same surgical
technique. … We found a reduced need for analgesia with
NSAIDs compared with placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - However, only a few
studies directly compared these approaches and the
total number of patients studied … The limited data available did not support a
significant benefit of fundoplication compared
with medical … Comparison of surgery with endoscopic
procedures
Of the three nonrandomized studies that compared
an … When esomeprazole 40 mg
was compared with omeprazole 20 mg, there was
a significant difference in favor … Improvement of esophageal pH
exposure compared with sham could not be
demonstrated for Stretta™.