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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
    January 01, 2025 - The third new RCT compared purified inhaled cannabis (6.3% THC and 8% CBD), 5 mg oxycodone tablets, … One (n=90) compared plant-derived topical hemp seed oil or diclofenac 1% gel versus placebo for knee … b Two trials are included in both the THC and CBD columns, as they compared THC to CBD, CBD/THC, and … Key Question 1: Benefits of cannabinoids for chronic pain compared with placebo in the short term (4 … Key Question 2: Harms of cannabinoids for chronic pain compared with placebo in the short term (4 weeks
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
    March 01, 2013 - Two RCTs compared metformin outcomes to a placebo group,55,56 one compared metformin to N-acetyl-cysteine … ,58 and one three-armed study compared metformin only, exenatide only, and both.57 In each case, compared … women scheduled for hysterectomy found that LNG-IUS users were more likely to cancel their surgery compared … with baseline.28-40 NSAIDs are effective when compared with placebo.35,39,68 Overall, 6 of 13 studies … Levonorgestrel-releasing intrauterine system compared to low dose combined oral contraceptive pills
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - For example, a cohort study that was conducted shortly after the marketing of celecoxib that compared … Similarly, if a cohort study enrolled current users and compared the rate of cardiovascular events for … Ray and colleagues compared incident users of statin medications to two control cohorts to evaluate … For example, Schneeweiss and colleagues compared mortality rates over a 180-day period in relation to … Intensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
    October 01, 2022 - Another nonrandomized study compared topiramate with carbamazepine, but the data were inconclusive. … No included studies compared surgical interventions to other treatment modalities (e.g., pharmacologic … No studies have compared pharmacotherapy with dietary or surgical treatments, a key target for future
  5. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
    September 01, 2011 - Compared with the oral route of administration, the SQ terbutaline pump uses lower doses (usual basal … Incidence of delivery < 32 weeks: The strength of evidence favoring SQ terbutaline pump compared with … The strength of evidence favoring SQ terbutaline pump compared with oral tocolytics or no treatment is … Neonatal hypoglycemia was reported in only one RCT that compared the SQ terbutaline pump with placebo … The strength of evidence favoring the SQ terbutaline pump compared with oral tocolytics for neonatal
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure-surveillance-160412.pdf
    May 29, 2025 - " " Key$Question$3," o" Compared"SMBP"monitoring"(with"or"without"additional"support)"with"one" … $Of$24$studies$that$ compared$SMBP$alone$versus$usual$care,$22$were$randomized$ controlled$trials$( … $Compared$with$the$usual$care$group,$diastolic$BP$decreased$ more$from$baseline$among$patients$in$the … $Of$24$studies$that$ compared$SMBP$alone$ versus$usual$care,$22$were$ randomized$controlled$trials … $This$meta" analysis$compared$ patients$who$self" monitor$BP$to$patients$ receiving$usual$care.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-266-cdd-executive-summary.pdf
    November 01, 2023 - The largest number of studies evaluated the effectiveness of cervical arthroplasty compared with ACDF … with cervical spondylotic radiculopathy or myelopathy at one or two levels (the Key Question that compared … ACDF than posterior cervical disc fusion, and a lower risk for any complication with laminoplasty compared
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
    February 26, 2013 - Compared to angiography alone, FFR has demonstrated in multiple randomized clinical studies that FFR … FFR) should not be compared to intravascular imaging techniques (i.e. … We did not include studies that solely compared revascularization versus medical therapy, or different … The first, a multicenter, retrospective, case matched study of 670 patients, compared angiography to … The second, a multicenter, prospective randomized study of 100 patients, compared the reliability and
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
    August 01, 2013 - difference between treatment strategies; in such cases, we describe the treatment strategies being compared … continuous risk scores appear to be similar and have the most discrimination of stroke events when compared … • Among AF patients on warfarin, one study (good quality; 48,599 patients) compared HEMORR2HAGES … The rates of ICH are significantly lower with both dabigatran doses (150 mg and 110 mg) compared with … Despite all the potential advantages of the new drugs demonstrated in the clinical trials when compared
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
    April 01, 2005 - Mortality in operated patients compared with the mortality in individually matched medically treated … Limitations • Only 2 RCTs compared angioplasty to medical treatment. Neither used stents. … serum creatinine or GFR, worsening kidney function, need for dialysis) after revascularization compared … The studies also noted decreased use of anti- HTN medications compared to baseline. … complication rate was significantly higher in combined renal artery and aortic reconstruction compared
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests … These had not been compared head-to-head in a clinical trial.19 3 Conversely, management strategies … For example, a decision analysis compared PET (as the sole diagnostic test) vs. an array of alternative
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
    October 01, 2016 - Compared with the Key Questions from the 2005 report, they expand the scope of the review to include … with EPA+DHA-containing fish oils may not have significant effects on infants’ gestational length compared … that maternal fish oil supplementation significantly increased the infants’ mean gestational age compared … Few trials compared n-3 FA dose, formulation (e.g., ratio of EPA to DHA), or source. … No trial compared different n-3 to n-6 FA ratios of supplements or intake.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
    October 01, 2011 - So, coxibs would be compared to placebo and then to non-selective NSAIDs. … Similarly, non-selective NSAIDs should first be compared to placebo/no Rx (observational studies are … You need to state that, compared to placebo, standard dose H2RAs are not effective at significantly … to placebo in patients prescribed a nonselective NSAIDs compared to placebo, double (full) dose H2 … to control of HP treatment; and as compared to placebo in low- dose aspirin users).
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
    December 01, 2012 - Although one trial compared spinal versus epidural anesthesia on the risk of deep vein thrombosis, … no events occurred in the groups compared. … The impact of prolonging prophylaxis for 28 days or longer on events was compared with prophylaxis … DTIs) compared with mechanical interventions on symptomatic objectively confirmed VTE, major VTE, PE … events occurred in the groups compared.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-1.pdf
    December 01, 2021 - All of the trials compared a mask versus no mask. … compared a mask versus hand hygiene17,18,20 and two trials compared a mask plus hand sanitizer versus … an N95 versus surgical mask and one28 compared a surgical versus cloth mask. … A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. … A cluster randomised trial of cloth masks compared with medical masks in healthcare workers.
  16. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
    January 01, 2012 - studies compared an active surgical technique, either laparoscopic utero-sacral nerve ablation (LUNA … ) or adhesiolysis, with surgical control (diagnostic laparoscopy).9,32,33 One study directly compared … Similarly, no studies reported benefit of LUNA compared with simple diagnostic laparoscopy. … One poor-quality study evaluated hysterectomy for CPP pain relief compared with nonsurgical management … a surgical approach with diagnostic laparoscopy or compared surgical with nonsurgical management.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
    August 19, 2011 - of prior noninvasive testing, type of PCI performed) influence the effect of IVDx techniques— when compared … angiographically demonstrated lesions within the same population  For KQs 4 and 5: Studies that compared … Analytic framework for intravascular diagnostic procedures and imaging techniques compared with angiography … For example, a study that reports that IVUS-guided stenting was compared to angiography-guided stenting … To improve clarity of the Key Question. 13 using an IVDx technique—when compared to angiography
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
    January 01, 2011 - biopsies due to false positives) of these imaging techniques have yet to be systematically assessed and compared … patients with specific clinical characteristics (e.g., family history, chronic pancreatitis, diabetes) compared
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
    August 01, 2014 - However, it is unknown whether measuring troponins improves risk prediction when compared with (or … 1.1 What are the operating characteristics of a troponin elevation (compared with no elevation) in … 1.5 Among studies that directly compared troponin testing in patients with CKD versus patients with … One study directly compared troponin T and I. … Only one study compared discrimination against a model of clinical factors.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
    June 01, 2022 - Metoclopramide No study in the original report compared these interventions, but in general, compared … MAGraine: magnesium compared to conventional therapy for treatment of migraines. … MAGraine: magnesium compared to conventional therapy for treatment of migraines. … ACHIEVE II trial: Ubrogepant compared to placebo for migraine attacks. [German]. … MAGraine: magnesium compared to conventional therapy for treatment of migraines.

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