-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_surveillance.pdf
August 30, 2014 - Schizophrenia
• A total of 41 studies compared outcomes for predefined subgroups. … No notable differences were observed for the subgroups
compared to the overall findings. … : Bipolar Disorder
Mood (mania)
SOE: Low
Seven studies compared haloperidol to
SGAs and found no … No notable differences were
observed for the subgroups compared
to the overall findings. … A significant
difference favored haloperidol
compared with ziprasidone for core
illness symptoms (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - without cirrhosis is associated with
worse quality of life measures and symptoms (primarily
fatigue) compared … There was no direct evidence on
clinical benefits associated with screening compared
with no screening … No study compared effects of screening with not screening
pregnant women. … The
studies of referral populations reported somewhat higher
rates of treatment (30–40 percent) compared … Although none of the studies assessing diagnostic accuracy
of noninvasive tests compared to liver biopsy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
April 01, 2005 - Mortality in operated patients compared
with the mortality in individually matched
medically treated … Limitations • Only 2 RCTs
compared
angioplasty to
medical
treatment.
Neither used
stents. … serum
creatinine or GFR,
worsening kidney
function, need for
dialysis) after
revascularization
compared … The
studies also noted
decreased use of anti-
HTN medications
compared to baseline. … complication rate
was significantly
higher in
combined renal
artery and aortic
reconstruction
compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
February 01, 2014 - We aimed to answer the questions
below by reviewing trials of adults that compared a higher
potency … KQ 3: Compared with higher dose statins and with one
another, do combination regimens differ in benefits … Data Synthesis
We compared lower potency statins in combination
therapy with higher potency statin … Three trials compared low-potency statin in combination
with niacin to mid-potency statin monotherapy … No study reported
on the effectiveness of niacin plus statin compared to
intensification of statin
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - Effective
Health Care
percent, compared with 80 percent in men,
which complicates diagnosis in women … These limitations are
generally considered to be minor when compared with the
benefits of the procedure … What is the accuracy of one NIT in diagnosing
obstructive and nonobstructive CAD when compared
with … Is there evidence that the use of NITs
(when compared with other NITs or with coronary
angiography) … Summary of accuracy of NITs compared with coronary angiography for diagnosing
CAD in women
Modality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - affect pain symptoms, length of hospital stay, recurrence risk,
quality of life, or need for surgery compared … symptoms, length of hospital stay, recurrence risk, quality of life, but may reduce
need for surgery compared … Studies that compared antibiotic regimens each evaluated different regimens. … whether patients who undergo colonoscopy after diverticulitis are at decreased risk of
dying from CRC compared
-
effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - Three RCTs
compared additional fentanyl (n = 40), morphine
(n = 40), and sufentanil (n = 50) versus … Similarly, three RCTs (n = 132) that compared the
addition of sufentanil found no difference between … One trial (n = 38) compared acupressure versus
sham control delivered preoperatively. … These were
compared with placebo/standard care, or a different
method of nerve blocks. … Eight trials
compared skin traction (n = 498) versus no traction
(n = 594) and found no significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - We did not find any head-to-head
RCTs that compared one biologic DMARD with
another. … No evidence exists on abatacept and rituximab
compared with other biologic DMARDs. … One nonrandomized, open-label trial
directly compared the tolerability of two biologic
DMARDs. … One open-label RCT compared synthetic DMARD use
with and without prednisolone. … Most of the other studies compared
combinations of biologic DMARDs and methotrexate
with monotherapies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_executive.pdf
March 01, 2012 - ANA, RF, and CCP tests in children and
adolescents with undiagnosed MSK pain and/or joint
swelling compared … comorbidities, and recent infections
modify the diagnostic performance of ANA, RF, and CCP
for pSLE compared … comorbidities, and recent infections
modify the diagnostic performance of ANA, RF, and CCP
for JIA compared … In studies using the case-
control design, children with known disease (i.e., JIA or
pSLE) were compared … Prevalence of IgM-,
IgA- and IgG-rheumatoid factors in seronegative polyarticular
disease compared
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - To ensure internal validity, treatment groups compared must have the same underlying risk for outcome … assumption needed for nonexperimental comparative effectiveness research is that the treatment groups compared … Cohort designs are easy to conceptualize and are readily compared to the randomized controlled trial, … Advantages
The oversampling of persons with the outcome increases efficiency when compared with the full … The case-cohort design is intended to increase efficiency, when compared with the nested case-control
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - What is the evidence for different models in palliative
care: integrative compared with consultative … , we were
unable to identify any validated tools that worked well in
this literature and could be compared … life,
only three (33 percent) showed a statistically significant
improvement with the intervention compared … enhance the educational intervention
showed statistically significant improvement in pain scores,
compared … In reference to the question of integrative
compared with consultative interventions, for the target
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Effective Health Care Program
2
reports about whether IOCM is associated with a reduction
in CIN risk compared … Five RCTs
compared two or more LOCMs in 826 patients.12-16 Twenty-
five RCTs compared IOCM with one … Nephrotoxicity of iso-
osmolar iodixanol compared with nonionic low-osmolar contrast
media: meta-analysis … The relative renal safety of
iodixanol compared with low-osmolar contrast media: a meta-
analysis of … A meta-
analysis of the renal safety of isosmolar iodixanol compared
with low-osmolar contrast media.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - /final.cfm
Number 15
Effective
Health Care
2
Several randomized controlled trials (RCTs) have
compared … Two RCTs compared the
rates or number of readmissions between RFA and
medical treatment. … WACA with or
without additional ablation lines compared their
efficacy to maintain sinus rhythm. … Another RCT compared WACA with
vs. without additional ablation of the superior vena
cava. … These observational
studies compared many different approaches to RFA.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
June 06, 2011 - Given that case management interventions and outcomes differ substantially for medical
illness when compared … addition, health care expenditures are substantially higher for patients with complex
care needs when compared … www.effectivehealthcare.ahrq.gov
Published Online: June 06, 2011 3
Case management will be compared … complex care needs, does case management improve patient
health outcomes
(as listed above) when compared … The outcomes will be compared among patient groups who receive different types of case
management.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - Low
Less improvement in disease activity (ACR
50) for anakinra compared with etanercept and
compared … treatment
comparisons)
(continued)
Greater improvement in disease activity (ACR
50) for etanercept compared … No significant
differences when compared with golimumab. … with
etanercept monotherapy or combination of
etanercept plus abatacept compared with
abatacept monotherapy … DMARDs; however, several studies suggest that
adverse events are more common with biologic DMARDs
compared
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - One new RCT (n=115) compared synthetic high-THC to CBD ratio and low-
THC to CBD ratio cannabis products … d One trial is included in both the synthetic THC and CBD columns, as it compared THC to CBD, CBD/THC … Key Question 1: Benefits of cannabinoids for chronic pain compared with placebo
in the short term (4 … Key Question 2: Harms of cannabinoids for chronic pain compared with placebo
in the short term (4 weeks … Compared with placebo, these interventions resulted in greater risk of common adverse
events (dizziness
-
effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/cervical-degenerative-topic-brief.pdf
March 01, 2023 - Anterior compared to posterior surgery
i. In patients with cervical radiculopathy?
ii. … What are the comparative effectiveness and harms of cervical laminectomy and
fusion compared to cervical … What are the comparative effectiveness and harms of cervical arthroplasty compared to
anterior cervical … Adjacent-level degeneration after bryan
cervical disc arthroplasty compared with anterior discectomy … Five-year clinical results of cervical total disc replacement compared with anterior
discectomy and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
October 01, 2017 - long-acting beta-agonists together as
controller and quick relief therapy
reduces asthma exacerbations
compared … There is a relatively smaller amount of published evidence
on intermittent ICS dosing as compared to … Conclusions
Compared to rescue SABA use, adding intermittent ICS
use appears to benefit children less … uncontrolled, persistent
7
asthma, adding LAMA to ICS controller or ICS plus
LABA controller compared … However, adding LAMA
to ICS controller compared to adding LABA to ICS
controller or increasing dosage
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
May 01, 2010 - moderate for
IMRT reducing late xerostomia and improving
quality-of-life domains related to xerostomia
compared … One study compared quality-of-life
outcomes between 3DCRT and 2DRT but did not
report a statistical comparison … moderate for
IMRT reducing late xerostomia and improving
quality of life domains related to xerostomia
compared … other
hand, the length of followup needed to study head and
neck cancer treatments is relatively short compared … The patient
groups being compared should be similar in terms of
key variables, such as anatomic site,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
August 01, 2016 - of a multicomponent program, were found to be more
effective at reducing disruptive behaviors when compared … with interventions that included only a child component or
when compared with control conditions. … examined the effectiveness
of concomitant use of psychosocial and pharmacologic
interventions when compared … review for patients in community settings is unclear.
�� No head-to-head studies were identified that compared … the
effectiveness of combined psychosocial and pharmacologic
interventions or that compared the effectiveness