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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
May 29, 2025 - Nomination
Population(s): Patients with symptomatic and asymptomatic CAD
Intervention(s): Tests will be compared … There are new primary studies that compared two or more
NITs, evaluated NITs in the asymptomatic populations
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effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - • Routine amniotomy plus oxytocin does not
differ compared with control treatment in
cesarean delivery … • Administration of intravenous fluids compared
with oral intake alone demonstrated a
reduction in … • Pulsatile administration of oxytocin is
associated with a longer duration of labor
compared with … • There is limited evidence that immediate
pushing has a shorter labor duration when
compared to … to 4 hours, had higher
cesarean delivery rates; but otherwise the use of
a partogram compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
July 01, 2010 - Twenty-two percent of users were obese, compared to 11 to
15% using other medications. … Statistics
We stratified the population of patients with DM into six groups to see how users of
exenatide compared … individuals who were obese was much higher among the exenatide users
(21.9% with an ICD-9 code for obesity compared … all of the HEDIS indicators for high quality care was
highest in the group begun on exenatide (26% compared … than any other group, including a much higher number
of visits to endocrinologists (1.73 per year compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
May 01, 2024 - training may outperform CBT + relaxation + education in QOL; MBSR
+ education may reduce attack frequency compared … with stress management
training + education; and biofeedback may reduce attack frequency compared … CBT, biofeedback, and relaxation training
may lead to lower migraine attack frequency and disability compared … clinically
important lower migraine disability and higher migraine-specific quality of life
(MSQOL) compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendices.pdf
January 01, 2025 - Strength of Evidence: Thiazides Compared With Active Comparators
Outcome
Strength of
Evidence Grade … with no
treatment;39
Lime powder
compared
with no
treatment40
2 RCTs39, 40
(277)
Medium … with no
treatment;
Lime powder
compared
with no
treatment
2 RCTs39, 40
(277)
Medium
(1 low … Strength of Evidence: Uric Acid–Lowering Agents Compared With Control
Outcome
Strength of
Evidence … Strength of Evidence: Oxalate-Lowering Agents Compared with Placebo
Outcome
Strength of
Evidence
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - Two studies compared beta blockers with digoxin, one
compared beta blockers with calcium channel blockers … ,
and one compared beta blockers with calcium channel
blockers in patients using digoxin. … One study compared
two beta blockers (sotalol and metoprolol) in patients
receiving digoxin. … alone, and four studies compared calcium
channel blockers with digoxin. … Few studies compared rate-control
therapies with procedural-based rhythm-control therapies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - These studies found the direct renin inhibitor to
have a greater reduction in blood pressure compared … to the
ACEI ramipril (two studies) and no significant difference
compared to the ARB losartan (one … ARB); of treatment success based on use of a single antihypertensive
Insufficient for ARBs compared … (continued) compared with the withdrawal rate associated with ACEIs. … Only nine studies compared ACEIs and ARBs
for periods longer than 1 year.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - two
DMARDs; two compared penicillamine to
hydroxychloroquine, and one compared
leflunomide to methotrexate … Thirteen trials
directly compared a DMARD to placebo. … Three RCTs directly compared two
DMARDs; two compared penicillamine to
hydroxychloroquine, and one … compared
leflunomide to methotrexate. … Thirteen trials
directly compared a DMARD to placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - two
DMARDs; two compared penicillamine to
hydroxychloroquine, and one compared
leflunomide to methotrexate … Thirteen trials
directly compared a DMARD to placebo. … Three RCTs directly compared two
DMARDs; two compared penicillamine to
hydroxychloroquine, and one … compared
leflunomide to methotrexate. … Thirteen trials
directly compared a DMARD to placebo.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-evidence-heart-disease.pdf
October 01, 2022 - Since the initial trials of CABG therapy, subsequent
trials have evaluated PCI as compared with CABG … evaluated the short- and long-term clinical benefit of PCI compared to OMT in a broad
population of … Three included studies that compared
PCI to OMT reported MACE. … with OMT and trials of CABG compared with PCI. … Angioplasty
Compared to Medicine. Am J Cardiol. Dec
15 1998;82(12):1445-50.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - No study directly compared
formulations. … RCTs
No eligible RCTs compared purified DPA formulations
versus placebo. … One trial compared 2.0 g/d SDA and 1.9 g/d
EPA+DHA+DPA in healthy people. … Few trials compared n-3 FA dose, formulation,
or source. … No trial compared different n-3 to n-6 FA
ratios of supplements or intake.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain-surveillance-151130.pdf
July 10, 2015 - We compared the conclusions of the included abstracts to the conclusions
of the original systematic … Progestogen-only
contraceptive pill compared with combined oral contraceptive in the treatment of pain … Progestogen-only contraceptive
pill compared with combined oral contraceptive in the treatment of pain … L. and Ferrero, S. 2014
Progestogen-only contraceptive pill compared with combined oral contraceptive … RESULTS: In group POP, 38/62 women (61.2%) were satisfied or very satisfied after treatment, compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
May 31, 2023 - Women who developed
pre-eclampsia (n=181) were compared to those in unaffected controls
(n=6,766). … In the pre-eclampsia group, compared to unaffected
controls, there was an increase in AIx-75 (p<0.0001 … The authors concluded that compared with
women who remain normotensive, women who develop pre-eclampsia … Significant increases in arterial stiffness measurements were noted
in women with preeclampsia compared … This needs to be
amplified and explained in further detail, call out paucity of work
compared to black
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effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - In this report, several monotherapy and metformin-based
combination medications were compared where … When compared with metformin plus a basal or
premixed insulin, metformin plus a GLP-1 receptor agonist … Comparative effectiveness of sulfonylureas compared with metformin for long-
term all-cause mortality … Efficacy and
tolerability of saxagliptin compared with glimepiride in elderly
patients with type 2 … Intensive blood-
glucose control with sulphonylureas or insulin compared with
conventional treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
November 19, 2009 - Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests … These had not been compared head-to-head in a clinical trial.19
3
Conversely, management strategies … For example, a decision
analysis compared PET (as the sole diagnostic test) vs. an array of alternative
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
January 01, 2010 - 11-16-10
2
(active surveillance vs. active treatment)
lead to improvements in health outcomes compared … Does use of the PCA3 assay lead to improved health outcomes when compared
with or in addition to use … the cost-effectiveness of using PCA3 assays to guide screening and
management for prostate cancer compared
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - Several major randomized controlled trials (RCTs)
have compared active treatments to active surveillance … The higher alpha/beta ratio of
surrounding tissues, such as the rectum, compared to prostate cancer, … Dose-fractionation regimens compared to each other
KQ 4. … Target volumes compared to each other [all grouped by type of
hypofractionation (MHF and UHF)
KQ 5. … Treatment planning and delivery techniques compared to each
other
Other comparators.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - standards for diagnosis,
outcomes
Validation of
instrument
compared with
reference
standard … P I C O T S
All ages
Diagnosed
with ADHD
N/A Feasible tools would
be compared with
reference … standards
for diagnosis,
outcomes
Validation of
instrument
compared with
reference
standard … failures
would be compared with other combinations after treatment failures. … Even when the known effect sizes of the compared interventions is large, the sample size
requirements
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
November 01, 2009 - What are the theoretical advantages and disadvantages of these therapies
compared to other radiation … We excluded from the literature scan studies that compared different treatment
plans/algorithms, as … What are the theoretical advantages and disadvantages of these therapies compared to
other radiation … What are the theoretical advantages and disadvantages of
these therapies compared to other radiation … Charged particles have different depth-dose
distributions compared to photons.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - Selected medical therapies have been shown to improve
walking distance in patients with PAD, compared … Of these,
four observational studies compared usual care with
endovascular intervention. … One RCT showed higher survival in
autologous vein graft compared with prosthetic graft. … The role of
DAPT compared with aspirin monotherapy is less certain. … A single RCT has compared clopidogrel with
aspirin, and three RCTs have compared clopidogrel plus
aspirin