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effectivehealthcare.ahrq.gov/products/colorectal-cancer-staging/research
September 10, 2014 - pooled the data using binomial-bivariate random-effects regression models (for diagnostic accuracy outcomes … ) or using random-effects meta-analysis (for under- and overstaging and under- and overtreatment outcomes … Nine studies reported on preoperative colorectal M (metastasis) staging. … The evidence was insufficient for drawing conclusions regarding other interim restaging outcomes for … rectal or colorectal cancer following initial treatment.
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effectivehealthcare.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
March 26, 2013 - Intermediate outcomes
Clinical outcomes Infectious outcomes (classified according to the definitions … ; normal for continuous outcomes) and link function (e.g., logit for binomial outcomes; identity for … Mechanical bowel preparation for elective colorectal surgery. … Colorectal Dis 2009 Jul;11(6):619-24. PMID: 18727727.
Eagye KJ, Nicolau DP. … Bowel preparation or not for elective colorectal surgery.
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effectivehealthcare-admin.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
December 01, 2019 - Intermediate outcomes
Clinical outcomes
Infectious outcomes (classified according to the … ; normal for continuous outcomes) and link function (e.g., logit for binomial outcomes; identity for … Mechanical bowel preparation for elective colorectal surgery. … Colorectal Dis 2009 Jul;11(6):619-24. PMID: 18727727.
Eagye KJ, Nicolau DP. … Bowel preparation or not for elective colorectal surgery.
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-staging/research
December 01, 2019 - pooled the data using binomial-bivariate random-effects regression models (for diagnostic accuracy outcomes … ) or using random-effects meta-analysis (for under- and overstaging and under- and overtreatment outcomes … Nine studies reported on preoperative colorectal M (metastasis) staging. … The evidence was insufficient for drawing conclusions regarding other interim restaging outcomes for … rectal or colorectal cancer following initial treatment.
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effectivehealthcare.ahrq.gov/products/colorectal-cancer-staging/research-protocol
May 21, 2013 - Recurrent Colorectal Cancer
Recurrent colorectal cancer arises in some patients after they have undergone … What is the impact of alternative imaging techniques on clinical outcomes? … What is the impact of alternative imaging techniques on clinical outcomes? … Outcomes
Test performance outcomes
Test performance (e.g., sensitivity, specificity, understaging, … Clinical outcomes .
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
May 18, 2021 - cancer health outcomes. … Trials that report on colorectal cancer outcomes with high-sensitivity gFOBT screening are currently … Two prospective cohort studies (n = 436,927) in US-based populations reported on colorectal cancer outcomes … outcomes and studies that report outcomes of patients who receive abnormal sDNA-FIT results but subsequently … Black and white differences in colorectal cancer screening and screening outcomes: a narrative review
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effectivehealthcare.ahrq.gov/products/colorectal-cancer-screening/research-protocol
May 18, 2011 - CRC screening improves health outcomes by detecting early stage cancer, which has a better prognosis, … Outcomes
KQ 1: Final Health Outcomes
CRC-specific or all-cause mortality
CRC incidence
KQs … 2 & 3: Diagnostic Outcomes
Sensitivity, specificity, positive predictive value, negative predictive … Outcomes
KQ 1: CRC incidence (or advanced neoplasia incidence if CRC incidence is not reported), … Colorectal cancer screening. [Review].
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-staging/research-protocol
December 01, 2020 - Recurrent Colorectal Cancer
Recurrent colorectal cancer arises in some patients after they have undergone … What is the impact of alternative imaging techniques on clinical outcomes? … What is the impact of alternative imaging techniques on clinical outcomes? … Outcomes
Test performance outcomes
Test performance (e.g., sensitivity, specificity, understaging … Clinical outcomes .
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www.ahrq.gov/sites/default/files/wysiwyg/professionals/prevention-chronic-care/decision/mcc/lewis_grant.pdf
September 01, 2013 - Models to Improve Colorectal Cancer Screening Decisions
Optimizing Prevention and Healthcare … Management
for the Complex Patient – Pioneer R21 Grants
Models to Improve Colorectal Cancer Screening … These decision aids can inform individual decisions
about colorectal cancer screening, based on the … Define appropriate
outcomes
4.C. … Updated 9/2013
http://www.shareddecisionmaking.org/Site/Welcome.html
Models to Improve Colorectal
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effectivehealthcare.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research-protocol
January 31, 2012 - Outcomes
KQ 1:
Final outcomes: Survival and quality of life
Intermediate outcomes: Time to progression … and final health outcomes. … outcomes (dotted line). … Abbreviations: CRC = colorectal cancer; KQ = key question
Figure 2. … and final health outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/colorectal-cancer-screening3
October 27, 2020 - rate ratio, 0.74 [95% CI, 0.68 to 0.80]) over 11 to 17 years of followup. 10 Most studies reported outcomes … Trials that report on colorectal cancer outcomes with HSgFOBT screening are currently lacking, although … -based populations reported on colorectal cancer outcomes after colonoscopy screening. 10 One study … outcomes and studies that report outcomes of patients who receive abnormal sDNA-FIT results but negative … Black and white differences in colorectal cancer screening and screening outcomes: a narrative review
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-screening/research-protocol
December 01, 2019 - CRC screening improves health outcomes by detecting early stage cancer, which has a better prognosis, … Outcomes
KQ 1: Final Health Outcomes
CRC-specific or all-cause mortality
CRC incidence … Outcomes
KQ 1: CRC incidence (or advanced neoplasia incidence if CRC incidence is not reported), … Grading the Evidence for Each Key Question
We will grade the strength of evidence for primary outcomes … Colorectal cancer screening. [Review].
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www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study18/colorectal-cancer-screening
May 18, 2021 - Assuming full adherence, screening outcomes and efficient strategies were similar by sex and race and … evaluation of the long-term outcomes of the full spectrum of screening strategies is not feasible. … Outcomes
Outcomes were simulated for a hypothetical cohort of average risk US adults who were unscreened … Validation of colorectal cancer models on long-term outcomes from a randomized controlled trial. … Black and white differences in colorectal cancer screening and screening outcomes: a narrative review
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-screening/research
December 01, 2019 - Structured Abstract
Objectives
To review the evidence on fecal DNA testing to screen for colorectal … cancer in adults at average risk for colorectal cancer. … Project Timeline
Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer … Screening: A Systematic Review
Research Protocol
Mar 13, 2024
Fiber Intake and Laxation Outcomes … https://effectivehealthcare.ahrq.gov/products/colorectal-cancer-screening/research
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research-protocol
December 01, 2019 - Outcomes
KQ 1:
Final outcomes: Survival and quality of life
Intermediate outcomes: Time to … and final health outcomes. … outcomes (dotted line). … and final health outcomes. … with final health outcomes (dotted line).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/c-7ARQE9RuXKjjpeLABkaH
March 01, 2007 - on these
outcomes, and the harms associated with aspirin and
NSAID use in healthy adults. … Fair Evidence is sufficient to determine effects on health outcomes,
but the strength of the evidence … Poor Evidence is insufficient to assess the effects on health outcomes
because of limited number or power … The USPSTF found good evidence
that [the service] improves important health outcomes and
concludes that … The USPSTF found at least fair
evidence that [the service] can improve health outcomes but
concludes
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/473PPVwoRhapCkN9SC-rue
May 18, 2021 - Assuming full adherence,
screening outcomes and efficient strategies were similar by sex and race and … of the long-term outcomes of the full spec-
trum of screening strategies is not feasible. … Outcomes
Outcomes were simulated for a hypothetical cohort of average-
risk US adults who were unscreened … Validation of
colorectal cancer models on long-term outcomes
from a randomized controlled trial. … Black and white differences in colorectal cancer
screening and screening outcomes: a narrative
review
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-2002
June 13, 2002 - screening technologies (for example, computed tomographic colography) are effective in improving health outcomes … Studies have not yet examined clinical outcomes with CT colography screening. … Teutsch, MD, MPH (Senior Director, Outcomes Research and Management, Merck & Company, Inc., West Point … Screening for Colorectal Cancer in Adults. … Colorectal cancer screening: recommendations statement.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
October 07, 2013 - The figure illustrates how aspirin chemoprevention may influence mortality outcomes (KQ 1) in adults … The figure also depicts how this intervention may affect intermediate outcomes, including cancer incidence … KQs 1, 2 (health and cancer outcomes):
Incidence of cancer
Cancer-related mortality
All-cause … mortality
KQs 3–5 (colorectal cancer outcomes):
Colorectal cancer incidence
Colorectal cancer … The most significant change is expansion of the scope of outcomes evaluated from colorectal cancer to
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening
April 17, 2014 - use colonoscopy as a reference standard
KQ 3: No comparator necessary
Outcomes … KQ 1: Colorectal cancer incidence (by stage), interval colorectal cancer; colorectal cancer–specific … A decision model is a mathematical simulation that projects the health outcomes that result from alternative … For example, a decision model can describe the expected population health outcomes of a clinical preventive … evidence review, which will provide the best available information on the linkages between screening and outcomes