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1. Recommendation: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
   May 18, 2021 - with annual FIT screening (approximately 850 more subsequent follow-up and surveillance colonoscopies … biopsies and adenoma removals), with 14.6 major bleeding events per 10,000 colonoscopies (95% CI, 9.4 … -19.9; 20 studies; n = 5,172,508) and 3.1 perforations per 10,000 colonoscopies (95% CI, 2.3-4.0; 26 … bleeding events per 10,000 colonoscopies (95% CI, 8.2-33.2; 4 studies; n = 5790) and 12.0 perforations … complications associated with screening, and the lifetime number of colonoscopies was used as a proxy

2. Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
   May 18, 2021 - 0.24-0.45]). 37 This study found that screening colonoscopies were associated with lower CRC mortality … Severe complications in colorectal cancer screening colonoscopies in the Valencian Community. … A register-based study: adverse events in colonoscopies performed in Sweden 2001-2013. … Epidemiology and quality control of 245,000 outpatient colonoscopies. … The quality of screening colonoscopies in an office-based endoscopy clinic.

3. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/Xbtq4oDQwVo7KgmSjnnDbz
   November 01, 2021 - Colonoscopies were conducted or supervised by “experienced” specialists. … The quality of screening colonoscopies in an office-based endoscopy clinic. … Process quality and incidence of acute complications in a series of more than 230,000 outpatient colonoscopies … Epidemiology and quality control of 245 000 outpatient colonoscopies. … Quality and safety of screening colonoscopies performed by primary care physicians with standby specialist

4. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/2Wc3FRHpVDPX2jT_WzjEXX
   July 31, 2020 - • Specificity is lower than that of FIT, resulting in more false-positive results, more follow-up colonoscopies … .12,13 Addi- tionally, modeling estimates that screening with sDNA-FIT annually would result in more colonoscopies … compared with annual FIT screening (approximately 850 more subsequent follow-up and surveillance colonoscopies … in Figure 2 and Figure 3) did not provide an efficient balance of the estimated lifetime number of colonoscopies … adults (ie, 1.5 to 4.2 colonoscopies per person over the lifetime and complications estimated as occurring

5. Modeling Study: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study18/colorectal-cancer-screening
   May 18, 2021 - The burden of screening was measured by the lifetime number of required colonoscopies. … In the models, lifetime colonoscopies ranged from 624 to 6817 per 1000, and the lifetime number of colonoscopy … Colonoscopy outcomes in average-risk screening equivalent young adults: data from the New Hampshire Colonoscopy … Lifetime Number of Colonoscopies and Life-Years Gained for a Cohort of 40-Year-Olds for Colonoscopy Screening … Instead they had a follow-up colonoscopy.

6. Archived: Modeling Study: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/colorectal-cancer-screening-june-2016
   June 15, 2016 - As in the 2008 analysis for the USPSTF, 9 the number of required colonoscopies was used as a measure … The LYG relative to the number of colonoscopies required and the efficient frontier for all colonoscopy … year interval between colonoscopies. … a It was assumed that the same test characteristics for screening colonoscopies applied to colonoscopies … Lifetime Number of Colonoscopies and Life-Years Gained for a Cohort of 40-Year-Olds for Colonoscopy Screening

7. Archived: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-2008
   October 15, 2008 - is that they may reduce the number of colonoscopies required and their attendant risks. … Colonoscopy Evidence is adequate to estimate the harms of colonoscopy. … In the models, the predicted total number of colonoscopies included those resulting from surveillance … per 1000 people for the "colonoscopy every 10 years" strategy, 2654 total colonoscopies for the "annual … The modeling analysis used life-years gained relative to the number of colonoscopies required for each

8. Archived: Final Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary4/colorectal-cancer-screening-2008
   October 15, 2008 - find good estimates of community endoscopy accuracy; serious harms occur in 2.8 per 1000 screening colonoscopies … Because of reporting limitations, complication rates could not be calculated for colonoscopies with and … Only 3 of these 11 studies reported the proportion of colonoscopies in which polypectomies were performed—the … Flexible sigmoidoscopy 6 cohort studies of screening colonoscopies Using screening colonoscopy to … Available data precluded determination of harms for colonoscopies with and without associated polypectomies

9. Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the USPSTF (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/vw-LTWCTZ_N5pAaydcNQTx
   June 21, 2016 - As in the 2008 analysis for the USPSTF,9 the number of required colonoscopies was used as a measure of … applied to colonoscopies for diagnostic follow-up or for surveillance. … The LYG relative to the number of colonoscopies required and the efficient frontier for all colonoscopy … Lifetime Number of Colonoscopies and Life-Years Gained for a Cohort of 40-Year-Olds for Colonoscopy Screening … year interval between colonoscopies.

10. Archived: Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/colorectal-cancer-screening-june-2016
    June 15, 2016 - The quality of screening colonoscopies in an office-based endoscopy clinic. … Process quality and incidence of acute complications in a series of more than 230,000 outpatient colonoscopies … Epidemiology and quality control of 245,000 outpatient colonoscopies. … Quality and safety of screening colonoscopies performed by primary care physicians with standby specialist … Colonoscopies were conducted or supervised by "experienced" specialists.

11. Screening for Colorectal Cancer: A Targeted, Updated Systematic Review (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/UCajZVxQEKLCgs59HV7ddE
    November 01, 2008 - community operators without clear quality guidelines; incomplete follow-through on second-look colonoscopies … Because of reporting limitations, complication rates could not be calculated for colonoscopies with and … Only 3 of these 11 studies reported the pro- portion of colonoscopies in which polypectomies were per … Flexible sigmoidoscopy 6 cohort studies of screening colonoscopies Using screening colonoscopy to estimate … Available data precluded determination of harms for colonoscopies with and without associated polypectomies

12. Archived: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-june-2016
    June 15, 2016 - years starting at age 50 years without increasing the lifetime number of colonoscopies. … For CT colonography, the findings depend on the perspective taken: if lifetime number of colonoscopies … In the case of colorectal cancer screening, this means considering how many colonoscopies (the primary … ), its efficiency ratio (ie, the incremental number of colonoscopies required to achieve an additional … The figures shows that the available strategies range from an estimated 1714 to 4049 total colonoscopies

13. Archived: Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evaluating-test-strategies-for-colorectal-cancer-screening-a-decision-analysis-for-the-us-preventive-services-task-force/colorectal-cancer-screening-2008
    October 15, 2008 - screening with colonoscopy with a 10-year interval (as long as results of the repeated colonoscopy were … The more effective strategies tended to be associated with more colonoscopies on average in a person's … by 2 per 1000 individuals for SimCRC, but would substantially decrease the number of colonoscopies by … every 10 years provided a reasonable ratio of incremental colonoscopies per life-year gained 10-35 … Once confirmed to be negative by colonoscopy, they then have colonoscopy screening every 10 years, as

14. Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/UPu84CV2CNuxR8kpVU6e3V
    November 01, 2008 - Outcome Measures: Number of life-years gained compared with no screening and number of colonoscopies … The more effective strategies tended to be associated with more colonoscopies on average in a person’ … We looked at the incremental number of colonoscopies relative to the life- years gained to determine … every 10 years provided a reasonable ratio of incremental colonoscopies per life-year gained (8–35) … Once confirmed to be negative by colonoscopy, they then have colonoscopy screening every 10 years, as

15. Colorectal Cancer Screening: An Updated Modeling Study for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/473PPVwoRhapCkN9SC-rue
    May 18, 2021 - In the models, lifetime colonoscopies ranged from 624 to 6817 per 1000, and the lifetime number of colonoscopy … Similarly, lack of adherence with 10-yearly colonoscopy, Table 2. … Instead they had a follow-up colonoscopy. … Lifetime Number of Colonoscopies and Life-Years Gained for a Cohort of 40-Year-Olds for Colonoscopy Screening … Colonoscopy outcomes in average-risk screening equivalent young adults: data from the New Hampshire Colonoscopy

16. Archived: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-2002
    June 13, 2002 - specimens and/or biennial testing detect a smaller proportion of cancers (27% to 39%) but require fewer colonoscopies … Colonoscopy Colonoscopy recently has been advocated for screening, usually at 10-year intervals or … Colonoscopy  The effectiveness of colonoscopy to prevent colorectal cancer or mortality has not been … In 2 studies of screening colonoscopies in more than 5,000 patients, 0.2% to 0.3% had major complications … Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies.

17. Screening for Colorectal Cancer: Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/n4sdjxShTApRE6UxvyYuzG
    November 01, 2008 - is that they may reduce the number of colonoscopies required and their attendant risks. … In the models, the predicted total number of colonoscopies included those resulting from surveillance … Serious complications—deaths from colonoscopies in asymptomatic populations or events requiring hospital … per 1000 people for the “colonoscopy every 10 years” strategy, 2654 total colonoscopies for the “annual … The modeling analysis used life-years gained relative to the number of colonoscopies required for each

18. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
    July 20, 2021 - Severe complications in colorectal cancer screening colonoscopies in the Valencian Community. … A register-based study: adverse events in colonoscopies performed in Sweden 2001-2013. … Epidemiology and quality control of 245 000 outpatient colonoscopies. … The quality of screening colonoscopies in an office-based endoscopy clinic. … Perforations and bleeding in a population-based cohort of all registered colonoscopies in Sweden from

19. Screening for Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6hyj7-3s6Qxs-brqhxPVxD
    June 06, 2017 - per 1000 Screened lifetime colonoscopies), its 0 30025020015010050 0 252015105 0 1610 12 148642 … arrhythmia, congestive heart failure, Colonoscopies per 1000 Screened cardiac or respiratory arrest … years starting at age 50 years without increasing the lifetime number of colonoscopies. … or screening plus surveillance colonoscopy. … TheCISNETmodels suggest that theavailable strategies range from an estimated 1714 to 4049 total colonoscopies

20. Screening for Colorectal Cancer: Clinical Summary (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/qSyg242Cz-X9DDwZg6GEhP
    Older than 85* Screen with high sensitivity fecal occult blood testing (FOBT), sigmoidoscopy, or colonoscopy … insufficient evidence) Screening Tests High sensitivity FOBT, sigmoidoscopy with FOBT, and colonoscopy … Colonoscopy and flexible sigmoidoscopy (to a lesser degree) entail possible serious complications. … Sigmoidoscopy every 5 years, with high-sensitivity fecal occult blood testing every 3 years • Screening colonoscopy