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1321. Ch 2-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
      January 01, 2011 - interest in which treatments are not assigned by the investigator but according to routine medical practice … exposures or treatments are not assigned by the investigator but rather by mechanisms of routine practice … treatment (e.g., frailty).8, 29 A good source for active comparator treatments are current treatment guidelines … Basic and Clinical Pharmacology and Toxicology. 2006;98:253-9. 29. … Evaluating medication effects outside of clinical trials: new-user designs.

1322. Fagerlin-notes-151007 copy-Teresa (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/fagerlin-presentation.pdf
      May 29, 2025 -  come from that, is that   we often have, probably not as often as we would like, a lot of good clinical … Another example is the mammography screening guidelines that came out 2 or 3 years ago and people were

1323. Long-Term Care for Older Adults Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
      November 07, 2012 - (Prepared by the Minnesota Evidence-based Practice Center under Contract No. 290-2007-10064-I.) … We followed EPC guidelines for the Discussion and Executive Summary sections. … If clinically meaningful means that one should be able to draw valid practice or policy implications … We have clarified that the purpose of the report is not for clinical decisionmaking but rather for policy … Reviewer #10 General This report is really less about clinical outcomes and more the comparison of 3

1324. Restless-Legs Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
      November 01, 2012 - For the fixed-dose trials, we analyzed only the doses recommended for current clinical practice if … • Many classes of drugs used in clinical practice such as opioids and sedative hypnotics have not … been evaluated in clinical trials … Physiotherapy Theory & Practice. 2011 Jul;27(5):345-51. PMID: 20977377. 22. … Poor effect of guideline based treatment of restless legs syndrome in clinical practice.

1325. CER 210: Disposition of Comments for Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
      January 01, 2020 - (Prepared by the RTI International–University of North Carolina at Chapel Hill Evidence- based Practice … The team was assembled based on clinical and methodological expertise; all members participated in … It refers to the review team who conducted the review, or Evidence-based Practice Center. … Usability The key points are described with sufficient clarity to make them accessible to both clinical … Strength of Evidence alogrithm, but I would prefer more detail on how this committee applied the guidelines

1326. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
      January 01, 2017 - We anticipate this report will be of primary value to organizations that develop guidelines for tonsillectomy … The clinical significance of this improvement is likely influenced by baseline disease severity and … Results of parallel randomized and nonrandomized clinical trials. … McMaster Centter for Evidence-based Practice. … (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290- 2015-00003-I.)

1327. Type-2-Diabetes-Medications-Update Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
      December 31, 2013 - Practice. … A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … A3 A superior new treatment: A pivotal trial or systematic review (or guidelines) whose results identified … (Prepared by Johns Hopkins University Evidence-based Practice Center under Contract No. 290-02-0018 … Initial Rapid Program Assessment (2005-2009) (Prepared by the Southern California Evidence-based Practice

1328. Treatment of Dementia Among Community-Dwelling and Institutionalized Medicare Beneficiaries (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
      May 01, 2008 - health care providers, patients, and policymakers seeking unbiased information about the outcomes, clinical … inhibitor, and memantine, a N-methyl-D-aspartate (NMDA) inhibitor, are effective9, and at least one clinical … pharmacological treatment. 11, 12 In a previous study, the authors13 reviewed 81 recent randomized clinical … Further research is necessary to isolate the determinants of use of these agents and to track changes in practice … work given that new drugs (specifically memantine) and other drug classes have entered the market and guidelines

1329. Autism Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
      October 01, 2012 - Finally, the right-hand column contains the recommendations of the Southern California Evidence-based Practice … Medicine; CER-Comparative Effectiveness Review; CBT-cognitive behavioral therapy; EPC- Evicence-based Practice … RPMT-Responsive Education and Prelinguistic Milieu Training; SCEPC-Southern California Evidence-based Practice … (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I.) … therapy or social casework or social group work or sociotherapy or speech therapy or treatment guidelines

1330. Measuring-Blood-Pressure Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
      January 01, 2012 - No studies reported on clinical outcomes. … on clinical events should also be made. … (Prepared by the Tufts Evidence-based Practice Center under Contract No. HHSA 290-2007-10055-I.) … clinical outcomes … reported clinical outcomes

1331. Untitled (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
      December 23, 2015 - Source: www.effectivehealthcare.ahrq.gov Published online: December 23, 2015 Evidence-based Practice … The NIMH issued the National Database for Clinical Trials Related to Mental Illness which intends to … establish a common informatics platform for exchanging data from clinical trials. … of intervention (e.g., mental health promotion, education and training, treatment, protocols and guidelines … The prevention and treatment of missing data in clinical trials.

1332. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
      October 01, 2010 - The dominant clinical features are chronic lung disease and pancreatic insufficiency with poor nutrition … Comparative Effectiveness Review, prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice … Version 2008) to limit the search to randomized controlled trials and the Scottish Intercollegiate Guidelines … The impact of baseline clinical status on the clinical outcomes of rhGH use was assessed in two trials … (Prepared by the University of Connecticut/Hartford Evidence-based Practice Center under Contract No.

1333. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
      August 24, 2012 - (Prepared by the RAND Evidence- based Practice Center under Contract No. 290-2007-10062-I.) … volume facilities and in response the American Society of Cataract and Refractive Surgeons had written guidelines … patterns, supplyside market conditions, or clinical outcomes that cannot be assessed in such limited … #13 Summary and Discussion The future challenge of bundled payments is around coordination of clinical … As such, we support the inclusion of risk-adjusted outcomes measures using clinical, audited data, and

1334. Machine-Learning-Tools-Appendix-C (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-c.xlsx
      January 01, 2024 - A professional information specialist will extract PICO elements from information needs in a common practice … PICO is a format for developing a good clinical research question prior to starting one’s research. … It is a mnemonic used to describe the four elements of a sound clinical foreground question. … Fast clinical trial identification using fuzzy-search elastic searches: retrospective validation with … Deep Neural Network for Reducing the Screening Workload in Systematic Reviews for Clinical Guidelines

1335. Comparative Effectiveness of Nonoperative and Operative Treatments for Rotator Cuff Tears | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/rotator-cuff-tear/research

1336. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
      October 01, 2009 - Based on clinical trial evidence, American College of Cardiology and American Heart Association guidelines … inhibitors or ARBs in close proximity to a revascularization procedure does not confer significant clinical … Key Question 1 suggested that patients with established ischemic heart disease do derive significant clinical … Thus, the true incidence 4 of harms with these therapies in environments outside of clinical trials … (Prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice Center under Contract

1337. Disposition of Comments for Technical Brief 21, Management Strategies To Reduce Psychiatric Readmissions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/psychiatric-readmissions_disposition-comments.pdf
      May 21, 2015 - (Prepared by the RTI-UNC Evidence-based Practice Center under Contract No. 290-2012-00008-I.) … should be achieved by improving clinical outcomes. … I think that it is common practice, now, to use "person first" language. … Secondary outcomes included measures of clinical engagement. … It makes it clear that current research does not support a direction for establishment of guidelines

1338. Diagnosis and Treatment of Tethered Spinal Cord | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/tethered-spinal-cord/research

1339. Dementia-Agitation-Aggression Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
      March 01, 2016 - effectively reduce agitation/aggression and improve patient quality of life would ideally support practice … Few studies examined such environmental and practice shifts (other than the training to generate more … American Psychiatric Association practice guideline for the treatment of patients with Alzheimer’s disease … Treatment of agitation in AD: a randomized, placebo-controlled clinical trial. … (Prepared by the Minnesota Evidence- based Practice Center under Contract No. 290-2012- 00016-I.)

1340. Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test of an Interactive, Web-Based Presentation and Discussion of Evidence | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/linking-evidence/methods-report