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effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
August 17, 2011 - health care through
critical assessment of relevant evidence for selected settings, interventions, and clinical … expected to work well for patients based on
known evidence and what actually happens in day-to-day clinical … Our assessment of the strength of the evidence will be based on
judgments about risk of bias, consistency … Beliefs and evidence in changing clinical practice. BMJ 1997 Aug
16;315(7105):418-21. … Technical Experts
Technical Experts comprise a multidisciplinary group of clinical, content, and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - health care providers, patients, and policymakers seeking unbiased information
about the outcomes, clinical … eMacLean Center for Clinical Medical Ethics, University of Chicago. … Using clinical judgment, we developed
several rules of thumb to aid in this matching process. … There were some ICD-9 codes representing clinical conditions where no match was
found among the clinical … International Classification of Diseases,
Ninth Revision, Clinical Modification.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
January 01, 2024 - stone present at baseline vs. absent NR NR NR NR NR NR NR NR NR NR NR NR NR NR AEs were assessed at clinical … stone present at baseline vs. absent NR NR NR NR NR NR NR NR NR NR NR NR NR NR AEs were assessed at clinical … Risk of Bias Judgment: Measurement of Outcomes Support of Judgment: Measurement of Outcomes Was the result … Risk of Bias Judgment: Selection of Reported Result Support for Judgment: Selection of Reported Result … Overall Risk of Bias Judgment Support for Overall Judgment
Bastug, 2021 Bastug F, Celik B.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - This report is not intended to
be a substitute for the application of clinical judgment. … Open-label extensions of clinical trials
present another type of clinical investigation that often … Treatment effects may also be attributable to secular trends in clinical care. … The two-period cross-over
clinical trial. Br J Clin Pharmacol.1979
Jul;8(1):7-20. … Incorporating historical
control data in planning phase II clinical trials.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - shifts in clinical outcomes. … Given the clinical relevance of this topic
and the possible lack of clinical information, it is essential … All domains will have response options of “yes,” “no,” or “unclear”
and allow justifications of such judgments … Herb-drug interactions: an overview of the clinical evidence. … Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88.
33.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
July 01, 2023 - implanted
devices can be a very serious complication, and prevention of infection is an important clinical … Dental care has been addressed in a recently published clinical practice guideline that included the … Medication-Related Osteonecrosis of the Jaw:
MASCC/ISOO/ASCO Clinical Practice
Guideline. … This report is not intended to be a substitute for the application of clinical judgment. … Most AHRQ documents are publicly available to use for
noncommercial purposes (research, clinical or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
April 01, 2016 - This report is not intended to
be a substitute for the application of clinical judgment. … [guideline
developer]
Clinical
significance
Reviews should include
considerations of clinical … Journal of clinical
epidemiology. 2008;61(6):531-6.
4. … Journal of clinical epidemiology.
2000;53(9):964-72.
22. Selph SS, Ginsburg AD, Chou R. … Rapid versus
full systematic reviews: validity in clinical
practice?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
August 23, 2013 - The judgments for the strength of evidence were
determined by two of the study authors. … Clinical Psychology &
Psychotherapy, 19(5), 411-419. … Journal of Consulting and
Clinical Psychology, 80, 649 -661. … However, this does not
mean that the person has clinical depression. … disagree, and for the most part the
authors justified their decisions (and I also agree with their
judgment
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - This report is not intended to be
a substitute for the application of clinical judgment. … design, conduct, and analysis,43 with the caveat that poor study reporting can hinder risk of
bias judgments … Clinical Pharmacology &
Therapeutics. 2022;111(1):108-15. doi:
10.1002/cpt.2255. … Journal of
clinical epidemiology. 2020;126. doi:
10.1016/j.jclinepi.2020.06.023. … Clinical
Oncology Research Statement.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - This report is not intended to be
a substitute for the application of clinical judgment. … design, conduct, and analysis,43 with the caveat that poor study reporting can hinder risk of
bias judgments … Clinical Pharmacology &
Therapeutics. 2022;111(1):108-15. doi:
10.1002/cpt.2255. … Journal of
clinical epidemiology. 2020;126. doi:
10.1016/j.jclinepi.2020.06.023. … Clinical
Oncology Research Statement.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - Furthermore, variation in how intravascular
diagnostic techniques are adopted in clinical practice … All forms of CAD and its clinical presentation were
included. … outcomes that directly affect patient well-
being or clinical status (e.g., death, acute MI, repeat … The overall judgment of risk
of bias was based on the overall study conduct, specifically
relating … These decisions are not always straightforward in clinical
practice.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-navigation-model-lung-cancer-rapid.pdf
December 01, 2018 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … One randomized
clinical trial found that navigated patients were more likely to receive a screening … Protocols and clinical trials relevant to Questions 2 and 3 ......................................... … Next Quality statement 4: Lung
cancer clinical nurse specialist.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
May 01, 2025 - This report is not intended to be
a substitute for the application of clinical judgment. … Additionally,
we consulted our clinical SMEs for relevant clinical practice guidelines.
2.2 Study … clinical practice guidelines. … The clinical SMEs critically reviewed the final
report to ensure accurate clinical contextualization … European AIDS Clinical
Society
Major revision version 12.0
of the European AIDS
Clinical Society
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
January 01, 2025 - /clinical-handover/implementation-toolkit-clinical-handover-improvement
https://www.safetyandquality.gov.au … /our-work/communicating-safety/clinical-handover/implementation-toolkit-clinical-handover-improvement … This report is not intended to be a substitute for the application of clinical judgment. … Clinical
Leadership & Infection Control. June 29,
2016. … A scoping
review of clinical handover mnemonic
devices.
-
effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - Design of the Women’s
Health Initiative clinical trial and observational study. … having
frequency data on other relatively rare benefits and harms
might help women to make their own judgments
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
October 01, 2012 - Executive Summary
Background
Sepsis is a serious condition with high
morbidity and mortality for which clinical … Again, the
duration of antibiotic therapy is often
undefined, and clinical features are of
limited … Comparator: Initiation, discontinuation, or intensification
of antibiotic therapy guided by clinical … The
choice of a noninferiority margin incorporates clinical and
statistical judgments.45 Studies should … Experience with a clinical
guideline for the treatment of ventilator-associated pneumonia.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - If the association between the exposure and one
clinical outcome is known from a study with strong … validity (such as from a clinical trial) and can be
reproduced in the study, the observed association … highlights the most common
elements for consideration in sensitivity analysis,
but some degree of judgment … Evaluating medication effects outside of
clinical trials: new-user designs. … The persistent
exclusion of older patients from ongoing clinical
trials regarding heart failure.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
September 13, 2011 - nonrandomized clinical trials or observational studies). … Assessing Applicability
Judgments of applicability for each outcome (including harms) will be performed … A national
clinical guideline. … Medication adherence: a review of the literature and
implications for clinical practice. … Because of their unique clinical
or content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - Clinical Outcomes
Clinical outcomes are perhaps the most common
category of outcome to be considered … is vulnerable to measurement error that arises
from subjective judgments or disagreement among
75 … The selection of clinical outcome measures may be
challenging when there are many clinical aspects … Clinical Outcome Assessment Qualification
Program. April 2012. … From
clinical trials to clinical epidemiology. Am J
Hypertens. 1996;9:178-83.
9.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
December 01, 2012 - This report is not intended to
be a substitute for the application of clinical judgment. … need to demonstrate clinical validity and clinical utility. … Clinical Utility
What is the clinical utility for use of the GEP results? … 28
• Clinical Validity. … Development of evidence on clinical utility requires robust evidence on clinical
validity.