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effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
April 01, 2017 - Conclusion:These recommendationswill provideupdated clinical guidance regardinguse of acceleratedpartial … Results
KQ1: Which patients may be considered for APBI
outside of a clinical trial? … The RTOG 9804 randomized clinical trial included
women with screen-detected DCIS, low to intermediate … Low-energy x-ray IORT for PBI should be used within
the context of a prospective registry or clinical … The ultimate
judgment regarding the propriety of any specific therapy
must be made by the physician and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - Understanding subgroup effects might help to better
inform clinical treatment decisions. … risk-of-bias assessments
and, when needed, a third investigator was consulted to
reconcile the summary judgment … practice in the United States.77,78 Few men were included
in clinical trials. … Clinical manifestations and
diagnosis of fibromyalgia in adults. … Clinical and economic
characteristics of patients with fibromyalgia syndrome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - This report is not intended to be a substitute for the application of
scientific judgment. … Rates of clinical response were moderate, 200 to 400 patients per 1,000 treated. … First, the nature of the condition relies on patient report and provider judgment for
diagnosis and … Rates of clinical response were moderate, 200 to 400 patients per
1,000 treated. … First, the nature of the condition relies on patient report and provider judgment for
diagnosis and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/linking-evidence-reviews-methods_0.pdf
October 01, 2018 - and
discussion of evidence) in integrating systematic review findings into organization-specific
clinical … This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … This scenario may not be
common for the clinical focus of most AHRQ reports. … operations decision-makers and people involved in
implementation of a clinical service.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
February 05, 2025 - Mindfulness involves focusing attention on the present moment and accepting what is without
judgment … This systematic review is intended to support the development of clinical
practice guidelines. … To address potential clinical heterogeneity, we plan to conduct separate analyses for individuals at … Technical Experts
Technical Experts constitute a multi-disciplinary group of clinical, content, and … Because of their unique clinical or
content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
September 25, 2024 - Mindfulness involves focusing attention on the present moment and accepting what is without
judgment … This systematic review is intended to support the development of
clinical practice guidelines. … To address potential clinical heterogeneity, we plan to conduct separate analyses for individuals at … Technical Experts
Technical Experts constitute a multi-disciplinary group of clinical, content, and … Because of their unique clinical or
content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
November 01, 2020 - This report is not intended to be
a substitute for the application of clinical judgment. … trial.pt.
23. clinical trials as topic.sh.
24. … trial.pt.
24. clinical trials as topic.sh.
25. … trial.pt.
17. clinical trials as topic.sh.
18. … Clinical Drug Investigation. 2010;30(8):489-505. PMID:
20586515.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
June 01, 2012 - affect applicability
Systematically abstract key characteristics that may affect applicability
Make judgments … determining the most important factors, systematically abstracting the key characteristics, making judgments … Outcomes
(from test results)
How studies addressed clinical outcomes selected for the review:
Earlier … The PICOTS element presented in this table is clinical outcomes. … How is the test used now in clinical practice compared to when the studies were completed?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
June 01, 2012 - affect applicability
Systematically abstract key characteristics that may affect applicability
Make judgments … determining the most important factors, systematically abstracting the key characteristics, making judgments … Outcomes
(from test results)
How studies addressed clinical outcomes selected for the review:
Earlier … The PICOTS element presented in this table is clinical outcomes. … How is the test used now in clinical practice compared to when the studies were completed?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
April 01, 2021 - suitable for
further action such as commissioning a systematic review or technical brief to inform clinical … treatment of acute pain in patients with opioid use disorder is insufficient to
guide a policy or clinical … This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Incorporates issues around both clinical
benefits and potential clinical harms
Yes
2d.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
April 01, 2021 - suitable for
further action such as commissioning a systematic review or technical brief to inform clinical … treatment of acute pain in patients with opioid use disorder is insufficient to
guide a policy or clinical … This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Incorporates issues around both clinical
benefits and potential clinical harms
Yes
2d.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
March 01, 2011 - This report is not intended to
be a substitute for the application of clinical judgment. … Randomization in
Clinical Trials: Theory and Practice: New
York: Wiley; 2002.
6. … Suspended judgment.
Significance tests of covariate imbalance in
clinical trials. … Analysis of covariance in
parallel-group clinical trials with
pretreatment baselines. … Variance
imputation for overviews of clinical trials
with continuous response.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - for each comparison and for
each outcome: data source, effect size, SOE rating; and rationale for judgments … We will use this information to
evaluate applicability of the evidence to real-world clinical practice … for this
approach is that
triptans and
NSAIDs are
already
recommended as a
standard of care in
clinical … Technical Experts
Technical Experts constitute a multi-disciplinary group of clinical, content, and … Because of their
unique clinical or content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
September 22, 2014 - Existing clinical guidelines
indicate that acute bronchitis and other acute RTIs that can be caused … A
2008 guideline by the United Kingdom’s National Institute for Health and Clinical Excellence
(NICE … Full-text articles will
be reviewed by two reviewers, with differences in judgment on eligibility resolved … National Institute for Health and Clinical Excellence. … Clinical
strategies, such as a clinical
prediction rule, that are
implemented at the system-level
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - For this review, we will use both this explicit scoring scheme and the global implicit
judgment about … Technical Experts
Technical Experts comprise a multi-disciplinary group of clinical, content, and … Because
of their unique clinical or content expertise, individuals are invited to serve as Technical … Reviewers
Peer reviewers are invited to provide written comments on the draft report based on
their clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
December 20, 2011 - The diagnosis of HF remains a difficult clinical
challenge. … Trial Registries, Clinical Study Results, and WHO Clinical Trials. … Quantitative synthesis
The decision to pool individual study results will be based on clinical judgment … National Clinical Guideline Centre. … Meta-analysis in clinical trials. Control Clin Trials
1986;7(3):177-88.
35.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
August 01, 2014 - This report is not intended to be a substitute for the application of
scientific judgment. … May inform and help
focus future clinical trials and data collection. … and statistical judgments. … May inform and help
focus future clinical trials and data collection. … *Comparison between procalcitonin measurement plus clinical criteria versus clinical criteria alone to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - We concur that
applying results to an individual patient lies in the domain of
clinical practice. … Most of the actual clinical
use of ESAs in practice are in patients with solid tumors. … There is evidence from
clinical trials to the contrary. … the assumptions in this section, and the basis
thereof, readers will be able to make more informed judgments … Our
judgment is that using a risk difference is not
appropriate under the circumstances here as
previously
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-post-transplant-complications-rapid-research.pdf
May 01, 2025 - This report is not intended to be
a substitute for the application of clinical judgment. … Additionally, we consulted our clinical subject matter experts (SMEs) for
relevant clinical practice … within the clinical community were missed and to identify publications that lacked
clinical applicability … clinical practice guidelines. … The clinical SMEs reviewed the
final report to ensure accurate clinical contextualization of any findings
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - given to the potential biases inherent in those
study designs when developing a research agenda and
clinical … A pair of researchers with complementary clinical and
methodological expertise was assigned to abstract … design,
(2) apply predefined criteria for quality and critical
appraisal, and (3) arrive at a summary judgment … To indicate the
summary judgment of the quality for the individual studies,
we used the summary ratings … We used these data to evaluate the applicability to clinical
practice, paying special attention to study