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effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - health care providers, patients, and policymakers seeking unbiased information
about the outcomes, clinical … We used our clinical judgment and the distribution of the intervals between heart failure
diagnosis … The absence of data on the clinical severity of HF and left ventricular function, potent
predictors … A clinical trial of the angiotensin-
converting-enzyme inhibitor trandolapril in
patients with left … Clinical Guideline Number
11. AHCPR Publication No. 94-0612 ed.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
December 14, 2015 - Clinical presentation
consistent with appendicitis? … We have used our best judgment to decide how to
organize study-specific information. … We do not make clinical
recommendations. … You always need a clinical
diagnosis first. … the Discussion section, because strength of
evidence assessment is based on unavoidably
subjective judgments
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
August 07, 2018 - The Prevention and Treatment
of Missing Data in Clinical Trials. … In our judgment, studies
with greater than 50 percent
attrition are fatally flawed, unless
the outcome … Journal of Clinical Psychiatry
2015; 76:1374–1384.
Thank you for the comment. … The judgment of “high risk of bias” is surprising, given that not only
was this Government- and not … trials that will
differ from routine clinical practice.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - • Settings
All KQs:
o Clinical setting
o Home setting
• Study type
KQ1 and KQ3:
o … Judgments for each criterion will be reported as “Yes” (low risk of bias), “No” (high risk of
bias), … Journal of Allergy and
Clinical Immunology. 2007;120(5):1139-45.
8. Noon L. … Clinical practice guideline: Allergic rhinitis. … Journal of Allergy and Clinical Immunology. 2012;129(3):S1-S8.
34. Higgins J, Green S.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - Inclusion of the clinical
classification table is important, but this is NOT the most up-to-
date clinical … No issues with the
methodology, but I defer judgment to other Reviewers who may
have more expertise … to-head trials have not been conducted, and thus there is little
possibility of being able to make judgments … to-head trials have not been conducted, and thus there is little
possibility of being able to make judgments … Questions 1 and 2 address issues that are raised
frequently in clinical practice and clinical trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
March 25, 2024 - NeuroImage: Clinical. 2020 Jan 1;27:102311. … clinical significance? both? … apart
from their potential use in
clinical diagnosis. … Public Reviewer 3 General Please include a table detailing how the final judgments
were made or include … The
certainty section is unorganized and does not clearly
state how the judgments were made.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - First, by using data from clinical trials and large cohort studies, evidence of
benefits and harms of … For this
review, we will use both this explicit scoring scheme and the global implicit judgment
about … Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight
and Obesity in Adults … Technical Experts
Technical Experts comprise a multi-disciplinary group of clinical, content, and … Because
of their unique clinical or content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
May 01, 2013 - In clinical setting, a
dominant philosophy has been, "Don't ask, don't
tell." … The MINI could be used with EPDs for clinical dx. … design, (2) apply
predefined criteria for quality and critical
appraisal, and (3) arrive at a summary judgment … Using the framework for the review agreed upon
by the Technical Expert Panel, our judgment was
that … Our judgment is that there has not been an
explicit consideration of the optimal sensitivity and
specificity
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - , clinical practices, and prognostic groups? … Did the sample represent patients who would be tested in clinical practice? … Measuring the accuracy of prognostic judgments in oncology. J Clin Epidemiol 1997 Jan;50(1):21-9. … Clinical outcomes
Clinical utility
Prospective clinical validation
Proof of concept
None of the above … Measuring the accuracy of prognostic judgments in oncology. J Clin Epidemiol 1997 Jan;50(1):21-9.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - , clinical practices, and prognostic groups? … Did the sample represent patients who would be tested in clinical practice? … Measuring the accuracy of prognostic judgments in oncology. J Clin Epidemiol 1997 Jan;50(1):21-9. … Clinical outcomes
Clinical utility
Prospective clinical validation
Proof of concept
None of the above … Measuring the accuracy of prognostic judgments in oncology. J Clin Epidemiol 1997 Jan;50(1):21-9.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/data-repository-reviews_white-paper.pdf
September 01, 2012 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … This report may be used, in whole or in part, as the basis for the development of clinical practice
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-improving-health-systems-access.pdf
August 01, 2019 - This report is not intended to be a
substitute for the application of clinical judgment. … • Clinical practice pathway. … ”
• Clinical practice pathway. … Clinical practice
pathway
Made evidence accessible
in clinical workflow
“In [four and a half months … Clinical practice
pathway
Platform limitations,
integration with practice
“The promise of clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-disposition.pdf
May 26, 2017 - My main reservation, as
indicated above, is that the clinical implications of the findings (i.e. … The report is of clinical relevance as many studies have highlighted
the high rates of medication use … the potential for
possible harm associated with most of the medications reviewed is
clearly of high clinical … This is the other major database in addition to Clinical Trials.gov. … Almost all of the studies reviewed are noted to have "small" sample
size, but the criteria for this judgment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
November 07, 2019 - How do criteria incorporate patient clinical characteristics?
KQ 1b. … Our broader search will include both databases
and gray literature sites, including Cochrane Clinical … As
such, we will use RAMESES project standards to guide our judgments in quality appraisal
tasks.29 … al.35 found tool-based approaches to be similar in the level of agreement to those using
unprompted judgment … Technical Experts
Technical Experts constitute a multidisciplinary group of clinical, content, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
April 01, 2013 - PR # 6 Methods Substantial amount of excluded studies: What type of design flaw lead to
judgment that … verification bias, some patients would
have had to undergo biopsy regardless of serum PSA level or clinician
judgment … Is there any clinical
relevance? … So clinical utility could not be
addressed. … Is there any clinical
relevance?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - Study
Results, and World Health Organization’s
Clinical Trials clinical trial registries; and
(c) … If our judgment was that clinical
heterogeneity of patient populations,
interventions, and outcomes … is to make
specific clinical recommendations or
encourage specific clinical behavior. … performance
measures will be required to exercise
clinical judgment where there are gaps in
the evidence … They also clarify few of the clinical issues faced in daily
practice.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
February 02, 2022 - explain pronounced disparities in maternal outcomes have faced data
source limitations, in part because clinical … Our review will include medical or clinical causes of
maternal mortality and severe morbidity, and also … No evidence is available, or the body of evidence precludes judgment. … Technical Experts
Technical Experts constitute a multi-disciplinary group of clinical, content, and … Because of their unique clinical or
content expertise, individuals are invited to serve as Technical
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
March 01, 2022 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Human Services endorsement of any derivative
products that may be developed from this report, such as clinical … independent peer reviewers, LSR teams need to include those with a high level of
methodological and clinical
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - Two overarching questions for quality as “value for judgment making”:
Are the results for the population … Background (2 of 3)
In considering quality as “value for judgment making,” two overarching questions … These are:
Spectrum bias
Partial verification bias
Clinical review bias
Observer or instrument variation … Clinical review bias Availability of clinical data such as age, sex, and symptoms during interpretation … Criteria for rating quality of trials of tests with clinical outcomes should not be very different from
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - Two overarching questions for quality as “value for judgment making”:
Are the results for the population … Background (2 of 3)
In considering quality as “value for judgment making,” two overarching questions … These are:
Spectrum bias
Partial verification bias
Clinical review bias
Observer or instrument variation … Clinical review bias Availability of clinical data such as age, sex, and symptoms during interpretation … Criteria for rating quality of trials of tests with clinical outcomes should not be very different from