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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-integrating-health-system-data.pdf
April 01, 2020 - This report is not intended to be a
substitute for the application of clinical judgment. … Anyone who makes decisions concerning the
provision of clinical care should consider this report in … and harms/safety of a given clinical service,
but rather, for example, understanding gaps in uptake … or use of a clinical service and questions
and considerations of how best to implement a given clinical … Health technology assessment in
Australia: a role for clinical registries?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - In a clinical trial all adverse events are collected
without regard to the investigator’s assessment … However,
the clinical question was what is the evidence for
benefits and risks beyond 3 years. … Report
highlights the clinical trial evidence on the subject. … While
clinical trials are without a doubt the highest level of
evidence,
observational studies can … What is skeptical and what is unnecessarily skeptical
is a subjective judgment.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - We will include unpublished
evidence only if enough details are available to make a judgment about eligibility … Trial" [Publication Type] OR
"Clinical Trial, Phase IV" [Publication Type] OR "Clinical Trial,
Phase … Trial" [Publication Type] OR
"Clinical Trial, Phase IV" [Publication Type] OR "Clinical Trial,
Phase … Trial" [Publication Type] OR
"Clinical Trial, Phase IV" [Publication Type] OR "Clinical Trial,
Phase … Trial" [Publication Type] OR
"Clinical Trial, Phase IV" [Publication Type] OR "Clinical Trial,
Phase
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
July 14, 2016 - or
policy judgments was well stated. … What are the
meaningful clinical outcomes that should be included in
studies and reports. … We agree with the clinical importance of
using what is known and yet, it would
be beyond the scope … That
leads me to rate clinical meaningfulness as low. … We appreciate your thoughtful clinical
recommendations.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - for each
comparison and for each outcome: data source, effect size, SOE rating; and rationale for
judgments … Technical Experts
Technical Experts constitute a multi-disciplinary group of clinical, content, and … Because of their unique
clinical or content expertise, individuals are invited to serve as Technical … Reviewers
Peer reviewers are invited to provide written comments on the draft report based on their
clinical
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effectivehealthcare.ahrq.gov/sites/default/files/mcda_webinar_transcript2.pdf
August 27, 2012 - It
is very important to understand that AHP and MCDA
techniques to help to improve judgment they start … analysis methods were developed in marketing and psychology
and behavioral economics to imitate consumer judgment … Of course, you can use clinical evidence from clinical
trial data so we can transform from large clinical … Preference data, finally, is to be used in
conjunction with clinical data. … It is just clinical data that
can't be directly observed.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
November 01, 2012 - Incorporates issues around both clinical benefits and potential clinical harms
2f. … Represents important variation in clinical care, or controversy in what constitutes
appropriate clinical … Determination of the clinical context or clinical logic has also been a challenge. … Clinical consultation is used to confirm a lack of evidence and the need to rely solely on
clinical … judgment.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
January 01, 2016 - by
at least one reviewer was obtained for further evaluation
by two reviewers, with differences in judgment … However, by setting the outcomes out
clearly, we hope to help decisionmakers form a judgment
appropriate … Delayed Prescribing Versus Clinical Score. … These studies were not pooled because of clinical and
methodological differences between studies. … National Institute for Health and Clinical Excellence.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - Consult content experts on a case-by-case basis to make judgments. … Examples of patient-relevant outcomes include history, future clinical events, and response to therapy … Application of linear regression procedures for method comparison studies in clinical chemistry, Part … sensitivity (Se) and specificity (Sp), ignoring imperfection of the reference standard but making qualitative judgments … their ability to predict patients’ history, risk propensity, or clinical profile.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - Consult content experts on a case-by-case basis to make judgments. … Examples of patient-relevant outcomes include history, future clinical events, and response to therapy … Application of linear regression procedures for method comparison studies in clinical chemistry, Part … sensitivity (Se) and specificity (Sp), ignoring imperfection of the reference standard but making qualitative judgments … their ability to predict patients’ history, risk propensity, or clinical profile.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
September 01, 2015 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Clinical Meta-Research Methodologist and
EBM Consultant
Adjunct Professor, University of Ottawa … The challenging task for clinical
and health policy decisionmakers is to balance considerations about … We relied on judgments of the
Cochrane authors regarding risk of bias of individual trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-unhealthy-alcohol-use-final.pdf
September 01, 2018 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Background
Evidence reviews by EPCs are used by groups, such as clinical professional organizations, … healthcare organizations, and Federal agencies, to inform clinical practice guideline
development … Division of General
Medicine & Clinical Epidemiology.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
January 01, 2011 - In addition, we will consider the clarity and consistency in
reporting as part of the overall judgment … KDOQI Clinical Practice Guidelines and Clinical Practice
Recommendations for Anemia in Chronic Kidney … Cooperative Multicenter EPO Clinical Trial Group. JAMA
1990 Feb 9;263(6):825-30. … NKF-K/DOQI Clinical Practice Guidelines for Anemia of Chronic Kidney Disease: update
2000. … Clinical aspects of iron use in the anemia of kidney disease.
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effectivehealthcare.ahrq.gov/products/examining
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
October 02, 2018 - The planned systematic review (SR) will inform a Clinical Update and Clinical Practice
Guideline to … We will explore the possibility of conducting a network meta-analysis of
clinical outcomes to compare … For rare categorical outcomes (with observed prevalence <5%) we will not
make such judgments, unless … Conversely, we will judge the evidence on “clinical equivalence” between two interventions
based on … Journal of Clinical
Child and Adolescent Psychology. in press.
16.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - Clinicians use the prothrombin time and INR as clinical
tools to guide anticoagulation therapy. … design, (2) apply predefined criteria for quality and
critical appraisal, and (3) arrive at a summary judgment … regarding applicability, with
associated signaling questions to help with these bias and
applicability judgments … For a
clinical prediction rule, we assumed that a c-statistic <0.6
had no clinical value, 0.6–0.7 had … There is also a need for future
studies in special populations and clinical scenarios.
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effectivehealthcare.ahrq.gov/products/n-1-trials/research
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effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - hDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON. … RCTs may be difficult to implement due to entrenched
clinical practice or to active consumer pressure … Second,
existing reviews on related topics or consultation with clinical experts may also identify … designs of studies used in pharmacoepidemiology and in
device and procedure registries can help inform judgments … Evaluating medication effects outside
of clinical trials: new-user designs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - hDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON. … RCTs may be difficult to implement due to entrenched
clinical practice or to active consumer pressure … Second,
existing reviews on related topics or consultation with clinical experts may also identify … designs of studies used in pharmacoepidemiology and in
device and procedure registries can help inform judgments … Evaluating medication effects outside
of clinical trials: new-user designs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
June 01, 2025 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … Human Services endorsement of any derivative
products that may be developed from this report, such as clinical … Therefore, identifying new treatments for chronic pain that are effective and safe is an important
clinical … Revisiting Review Scope
The clinical, policy, and regulatory context in which living reviews are conducted