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Showing results for "clinical judgment".

161. Disposition of Comments for CER 167 Renal Masses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
     February 24, 2016 - This is an important point for the panel to clarify for the calculation as well as from a clinical … As it stands the question being asked frankly has only limited clinical utility. … also have the impression that information about fine needle biopsies may be insufficient for making a judgment … Such judgment requires a ideally predefined threshold for equivalence. What was that threshold? … Such a threshold would also have been necessary for judgments about precision.

162. CER 174 Executive Summary: Imaging for the Pretreatment of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
     April 01, 2016 - this means reporting the percentage of patients who were over- or undertreated (based on authors’ judgment … particular clinical circumstances of each patient case. … conclude that two modalities are approximately equivalent for an outcome, we used the independent judgment … staging alone at detecting any distant metastases (Strength of Evidence: low) Our strength-of-evidence judgments … ACR appropriateness criteria non-invasive clinical staging of bronchogenic carcinoma.

163. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
     April 15, 2021 - • Peer reviewers suggested more information for clinical context. … American Psychiatric Association Introduction Clinical and Policy Context. … We also added some additional text to the overview to explain the reasons for the insufficient judgment … We also added some additional text to the overview to explain the reasons for the insufficient judgment … Discussion Implications for Clinical Practice and Education.

164. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - However, it results in limited ability to use clinical and epidemiologic judgment to draw conclusions … Corticosteroid free clinical remission was defined as clinical remission in patients who had not received … However, there is no footnote stating what this judgment was based on (and table 5, page 531, does not … allocation concealment/sequence generation; no information is given how this influenced the overall judgment … improve with standard GRADE style evidence profiles, as finding, interpreting, and re-assessing the judgments

165. Project Name: (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_disposition-comments.pdf
     October 25, 2011 - While we don’t disagree, the decisions of whether, when, and how to meta-analyze are judgment calls. … We agree it was a judgment call, but the methodologists and the domain expert agreed that this was a … We have clarified the term “clinical outcomes” to clarify that we mean “objective clinical outcomes” … judgment, but the authors do not make this distinction. … judgment and arbitrary thresholds.

166. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - This report is not intended to be a substitute for the application of scientific judgment. … in order to effectively inform the design of proposed new clinical research studies. … For some clinical questions, there may be no SR available. … research area which only a primary research is likely to have, and requires a degree of judgment in … Getting it right: being smarter about clinical trials. PLos Med. 2006;3(6):756-61. 36.

167. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
     January 01, 2012 - Over time, damage spreads from the brain’s memory center to areas that control thinking and judgment … Clinical development pipeline. [internet]. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form.

168. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
     November 19, 2009 - In such cases, it is not feasible to directly compare all patient management strategies in clinical … Judgment calls are being made in this process, some of which are discussed below. … The clinical management of suspected herpes virus encephalitis. A decision-analytic view. … How to use a clinical decision analysis. B. … How to use a clinical decision analysis. A. Are the results of the study valid?

169. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - Judgment on the potential for selective outcome reporting bias will be based on reporting patterns for … in this assessment, we will explicitly present all operational decisions and the rationale for our judgment … BRCA in breast cancer: ESMO Clinical Practice Guidelines. … Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Feb … Meta-analysis in clinical trials. Controlled clinical trials. 1986 Sep;7(3):177-88.

170. Disseminating Findings From EPC Reports: Pilot Project of Three Products (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-disseminating-findings_0.pdf
     October 01, 2018 - This report is not intended to be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … Clinical Director CT 2. Clinical Director MRI 3. Clinical Director Neuroradiology 4. … EtD frameworks were developed for making clinical recommendations, coverage decisions, and health system … We felt that this was a better fit than the clinical decision framework since the decision makers were

171. Disposition of Comments for CER 159 Insomnia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
     December 30, 2015 - me whether the overall strength of evidence was based on a quantitative tallying of criteria, or a judgment … To date two publications describing two clinical trials of suvorexant have been published. … me whether the overall strength of evidence was based on a quantitative tallying of criteria, or a judgment … While these methods are fairly transparent in determining the individual components of SOE, judgment … To date two publications describing two clinical trials of suvorexant have been published.

172. Making Healthcare Safer IV Rapid Response: Acute Care Nursing Staff Shortages That Compromise Patient-to-Nurse Ratios (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research.pdf
     April 01, 2025 - judgment to assign patient's acuity. … judgment to implement, which limits consistent use of the tool. … judgment necessary to use a patient acuity tool.43 The participatory scheduling tool was also noted … https://www.aacn.org/clinical-resources/staffing https://www.aacn.org/clinical-resources/staffing … This report is not intended to be a substitute for the application of clinical judgment.

173. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - Table 1 outlines the antiplatelet and anticoagulant therapies available for each clinical scenario: … Current clinical practice regarding the dose and timing of oral P2Y12 treatment varies dramatically. … design, 2) apply predefined criteria for quality and critical appraisal, and 3) arrive at a summary judgment … To indicate the summary judgment of the quality of the individual studies, we will use the summary ratings … trial[pt] OR "clinical trial"[tw] OR "clinical trials"[tw] OR "evaluation studies"[Publication Type

174. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - Key Questions On the basis of input from clinical experts during the development of our protocol, we … Judgment on the potential for selective outcome reporting bias was based on reporting patterns for each … We used these comparisons to inform our judgments on applicability of study findings to clinical practice … For Key Questions 1 and 2, we assessed the strength of evidence by integrating our (subjective) judgments … Ten-year risk of false positive screening mammograms and clinical breast examinations.

175. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
     July 01, 2012 - Alternatively, in the absence of direct empirical information from trials, one could use judgment to … Cross-tabulation of PET results and actual clinical status among patients with initial clinical examination … suggestive of Alzheimer’s AD in Long-Term Clinical Evaluation No AD in Long-Term Clinical Evaluation … In the clinical scenarios of interest, patients with a positive test result (either by clinical examination … How to use a clinical decision analysis. B.

176. Prostate-Cancer-Test Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
     October 14, 2011 -  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and improved … of life, and the potential clinical and personal harms of PCA3 testing and/or related intervention … Testing complies with requirements of the Clinical Laboratory Improvement Act (Public Law 100-578). … The study has one or more flaws that, in the judgment of the EPC staff, are highly likely to bias or … Judgments of applicability for each outcome (including harms) will be performed separately from assessments

177. S103 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s103.pdf
     October 01, 2007 - Curtis, PhD, Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969 … To answer this, we rely on clinical judgment, paying careful attention to contraindications to the treatments … ) �-blockers that have clinical trial evidence of a survival benefit in heart failure, or whether the … Again, the placement and length of the partitions will depend on the specific clinical question and when … Handbook of Statistics in Clinical Oncology. 2nd ed.

178. Asthma-Provider-Adherence Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
     May 01, 2013 - We report judgments for each criterion as “Low risk of bias,” “High risk of bias,” or “Unclear risk … These judgments were made by one reviewer and checked by another, with disagreements discussed with … Our judgments were first based on the ability to make a conclusion (if not able to make a conclusion … Clinical pharmacy support. … Clinical pharmacy support.

179. Cancer-Pancreas Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
     August 09, 2013 - which clinical situations, and in what order can be difficult. … Instead, the imperfect reference standard is clinical followup. … followup • Accuracy of resectability judgment 1b P1 Same list as KQ 1a Another test from the list … followup • Accuracy of resectability judgment 1c P1 Single imaging test: same list as KQ 1a Multiple … Clinical manifestations, diagnosis, and staging of exocrine pancreatic cancer.

180. Methods Future Research Needs Number 8: Framework for Considering Study Designs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
     March 01, 2012 - This report is not intended to be a substitute for the application of scientific judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … Weighing Different Considerations in Study Designs Report authors will need to use judgment to arrive … the intervention or control by a method that is not random (e.g., date of birth, date of admission, judgment … An example is the assessment of screening programs with respect to clinical outcomes.