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Total Results: 598 records

Showing results for "clinical judgment".

121. A Framework for Conceptualizing Evidence Needs of Health Systems (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-framework-for-conceptualizing-evidence-needs_0.pdf
     December 01, 2017 - This report is not intended to be a substitute for the application of clinical judgment. … conjoint analysis, decision analytic modelling, or other quantitative approaches to clarifying value judgments … 200852 Canada Framework for presenting evidence to facilitate decisionmaking in which scientific judgments … are separated from value judgments • Used Multicriteria Decision Analysis (MCDA) for clarifying value … judgments • Developed a Value Matrix encompassing quality of evidence, impact on disease, economic

122. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - This target is based upon retrospective clinical data correlating clinical response with specific Cmax … Clinical response or mechanical ventilation? b. Morbidity or mortality? c. … PK/PD measures  Different targets of PK/PD measures  Usual care (e.g., physician discretion or judgment … PK/PD measures o Different targets of PK/PD measures o Usual care (e.g., physician discretion or judgment … Comparative Effectiveness Review Methods: Clinical Heterogeneity.

123. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
     September 29, 2011 - This report focuses on women because of the differences in clinical presentation and coronary anatomy … Clinical presentations CAD is the presence of atherosclerosis in the epicardial coronary arteries … design, (2) apply predefined criteria for quality and critical appraisal, and (3) arrive at a summary judgment … To indicate the summary judgment of the quality of the individual studies, we will use the summary … Representation of women in randomized clinical trials of cardiovascular disease prevention.

124. Presentation of Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
     April 01, 2012 - This report is not intended to be a substitute for the application of scientific judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … EPCs should exercise judgment in determining the level of detail based on their understanding of the … detail of the FRN description will depend on the state of the science, and EPCs should use their judgment … Actions that facilitate aggregations of results For each clinical area, to facilitate comparisons

125. Standardized Library of Atrial Fibrillation Outcome Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-afib.pdf
     November 15, 2018 - This report is not intended to be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … As a final step in the harmonization process, clinical informaticists map the narrative definitions … Harmonized Outcome Measures for Use in Atrial Fibrillation Patient Registries and Clinical Practice. … A low ejection fraction without clinical presentation does not qualify as heart failure.

126. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - An expanded discussion of the clinical implications of the main findings might increase the value of … the report to clinical readers. … Reviewer 3 Methods The clinical descriptions and definitions are clear and accurate. … judgment. … This requires knowing the evidence about benefits, harms and applicability, and using clinical judgment

127. final Fibromyalgia CER protocol_3-31-14 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
     April 03, 2014 - consultation between the two reviewers, a third investigator will be consulted to reconcile the summary judgment … No evidence is available or the body of evidence precludes judgment. G. … Clinical manifestations and diagnosis of fibromyalgia in adults. … Clinical applications of visual analogue scales: a critical review. …  (182851)   46          clinical  trial.pt.

128. Hi Les, (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
     January 01, 2009 - Bossuyt, Ph.D.c aNational Health and Medical Research Council Clinical Trials Centre, University … To define all potential changes in outcomes, clinical experts involved in the diagnosis and management … • Other consequences of clinical decisions, such as increased adherence to treatment or adoption … This depends on judgments about the plausibility of assumptions that the treatment effects observed … If such trials are not available, conclusions about the benefits of adding MRI have to depend on judgments

129. Cad-Women-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
     June 01, 2012 - Based on their clinical and methodological expertise, two researchers were assigned to abstract data … design, (2) applied predefined criteria for quality and critical appraisal, and (3) made a summary judgment … To indicate the summary judgment of the quality of the individual studies, we used the summary ratings … , treatment decisions, and clinical outcomes. … Assessing clinical and demographic factors that influence diagnostic accuracy.

130. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - This report is not intended to be a substitute for the application of clinical judgment. … judgment of the review team strongly suggests should have been prespecified • Addition of an outcome … • Although likely to occur infrequently, authors should be contacted when in the review team’s judgment … should contact researchers and invite them to provide necessary information, when in the review team’s judgment … • Abstracts and other reports of non-English language studies should be tracked to inform a judgment

131. Disposition of Comments: Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
     April 10, 2025 - ) in which we assessed each domain of certainty (e.g., inconsistency, risk of bias) and made a judgment … Reviewer #3 Results 3.2.2.1.1. section would benefit from an explicit mention of the SOE and how the judgments … We understand the discomfort of the reviewer with making SOE judgments without a meta-analysis. … We made these judgments via discussions of our clinical experts and methodologists. … Annual Review of Clinical Psychology, 20, 21-47.

132. Cell-Free-Dna-Final-App-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
     January 01, 2025 - Domain 1 Judgment: Could the selection of patients have introduced bias? … Domain 2 Judgment: Could the conduct or interpretation of the index test have introduced bias? … Domain 3 Judgment: Could the reference standard, its conduct, or interpretation have introduced bias? … Domain 4 Judgment: Could the patient flow have introduced bias? … 2.2 Reason 3.1 What was the judgment of concern about conflicts of interest of funders and of primary

133. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - What is the comparative clinical management of the different imaging strategies when used for staging … outcomes (clinical management, survival, and quality of life). … nonstatistically significant difference for both sensitivity and specificity, as well as independent judgments … Summary of evidence on comparative accuracy for KQ2 Comparison and Staging Judgment D ir ec tn es … favors PET/ CT # Studies, # Patients, and Overall Study Limitations 14 Comparison and Staging Judgment

134. Facilitating the Implementation of EPC Reports_Methods Research Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-facilitating-implementation-pilot.pdf
     October 01, 2019 - This report is not intended to be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … Human Services endorsement of any derivative products that may be developed from this report, such as clinical … guide or a tool) to assist health systems interested in a quality improvement (QI) project in the clinical … Topic Identification We aimed to identify ongoing or planned QI effort in the clinical areas of recently

135. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
     August 10, 2010 - How do a) underlying prevalence of ADHD, and b) rates of diagnosis (clinical identification) and treatment … Study Design, and Publication types Inclusion: Full-text reports of clinical trials and comparative … Quantitative synthesis The decision to pool individual study results will be based on clinical judgment … Clinical heterogeneity will be assessed by considering any potential differences in participants amongst … Clinical Pediatrics 38(4)()(pp 209-217), 1999 Date of Publication: 1999 1999;(4):209-17. 11.

136. White Paper: Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
     December 01, 2024 - This report is not intended to be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning the provision of clinical care should consider this report in … Most AHRQ documents are publicly available to use for noncommercial purposes (research, clinical or … These reviews, which include Clinical (or Medical) Reviews and Statistical Reviews, are collectively … years,5 perhaps largely due to the relatively recent introduction of clinical trial registries.

137. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
     June 15, 2010 - actions following the failure of one adequate course of SSRI based on current (< 5 years) clinical … trial registries (i.e., clinical.trials.gov, Current Controlled Clinical Trials, Clinical Study Results … , WHO Clinical Trials), grants and federally funded research (i.e. … However, there is some evidence that certain items where greater judgment is required may be prone to … judgment with regards to comparability of study populations, treatments, and outcome measures.

138. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
     November 20, 2014 - The first aspect of consistency was a judgment about whether the studies should be pooled together … After this decision was made, we also used subjective judgment after studying the data—examining the … Our clinical experts confirmed that having per-lesion data for the liver was useful clinical information … It would be difficult not to have a threshold effect with imaging tests that require subjective judgment … General Comments: This is a topic of critical clinical importance.

139. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - adequacy of the reference standard; systematic reviewers should consult content experts in making such judgments … quantifies the impact of patient management strategies that include testing on (usually long-term) clinical … One could obtain naïve estimates of index test performance and make qualitative judgments on the direction … a naïve and “adjusted” analyses would reinforce assessments of a test if they both lead to similar clinical … Application of linear regression procedures for method comparison studies in clinical chemistry, Part

140. bipolar-disorder-treatment-protocol-140623 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
     June 23, 2014 - When the two investigators disagree, a third party will be consulted to reconcile the summary judgment … No evidence is available or the body of evidence precludes judgment. … trial/ 39 clinical trial, phase i.pt. 40 clinical trial, phase ii.pt. 41 clinical trial,  phase … iii.pt. 42 clinical trial, phase iv.pt. 43 controlled clinical trial.pt. … trial.pt. (484436) 47 exp clinical trials as topic/ 48 or/33-­‐47   49 (clinical adj trial$).tw.