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461. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
     November 01, 2008 - Publication bias in clinical research. … Reporting of 6- month vs 12-month data in a clinical trial of celecoxib. … British Journal of Clinical Pharmacology. 2004;57(5):616–21. 42 Strom BL. … Clinical Trials 2004;1:60– 79. 51 Rubin DB. … The hazards of scoring the quality of clinical trials for meta-analysis.

462. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
     February 01, 2008 - The clinical significance, natural history, and comparative effectiveness of treatments in PSA-detected … The effect of provider volumes on clinical outcomes in men with localized prostate cancer is not well … Based on nonrandomized data, the absolute risks of clinical and biochemical outcomes (including tumor … • Biochemical/clinical progression or recurrence: At 5 years, biochemical or clinical progression … • Biochemical/clinical progression or recurrence: EBRT + ADT reduced clinical failure at any site,

463. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
     November 01, 2008 - Publication bias in clinical research. … Reporting of 6- month vs 12-month data in a clinical trial of celecoxib. … British Journal of Clinical Pharmacology. 2004;57(5):616–21. 42 Strom BL. … Clinical Trials 2004;1:60– 79. 51 Rubin DB. … The hazards of scoring the quality of clinical trials for meta-analysis.

464. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
     December 01, 2011 - CDI is an active topic in the literature as well as a vital clinical concern. … cure, clinical recurrence, or mean days to resolution of diarrhea. … The clinical differences of changes in cut-points are also unknown, however, so the clinical significance … Clinical Infect Dis 2009 Mar 1; 48(5):568–76. 2. McDonald LC. … Clostridium difficile testing in the clinical laboratory by use of multiple testing algorithms.

465. Chicago-Area DEcIDE Center (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
     May 01, 2009 - health care providers, patients, and policymakers seeking unbiased information about the outcomes, clinical … eMacLean Center for Clinical Medical Ethics, University of Chicago. … Using clinical judgment, we developed several rules of thumb to aid in this matching process. … There were some ICD-9 codes representing clinical conditions where no match was found among the clinical … International Classification of Diseases, Ninth Revision, Clinical Modification.

466. Disposition of Comments for CER 182 Glasgow Coma Scale (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
     January 12, 2017 - Therefore, we did not specify a specific target population for the report, which differs from clinical … We do not state that clinical trials are needed to change recommendations regarding which scale is … decisionmaking and clinical outcomes. … No similar study on effects on clinical outcomes was available for Key Question 3. … Given the likely clinical equipoise, we think an RCT would also be justified.

467. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
     October 20, 2011 - Background and Clinical Context HCV is the most common blood-borne pathogen in the United States; … Food and Drug Administration nor are they widely used in clinical practice in the United States. … Targeted population of asymptomatic patients at higher risk for HCV infection, based on clinical or … We will include observational studies, systematic reviews, and clinical trials. … Controlled Trials, Clinical Trial Results, WHO Trial Registries), grants databases (NIH RePORTER,

468. Research Protocol: Characteristics of Existing Asthma Self-Management Education Packages (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-education-protocol.pdf
     January 01, 2018 - AS-ME can also be implemented in a variety of clinical and nonclinical settings. … They may be taught how to measure peak flow and monitor their clinical symptoms for warning signs. … Is there a clinical gatekeeper (e.g., referral or login permission needed)? … o Clinical/educational background o Training process o Certification o Guidance in privacy rules, … What are the most important clinical and psychosocial goals for patients who engage in AS-ME?

469. Crosscutting-Horizon-Scan-High-Impact-1506 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form.

470. Crosscutting-Horizon-Scan-High-Impact-1512 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form.

471. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … National Institute for Health and Clinical Excellence (NICE). … National Institute for Health and Clinical Excellence (NICE).

472. Behavioral Programs for Type 2 Diabetes Mellitus: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician.pdf
     November 01, 2016 - This summary is provided to assist in informed clinical decisionmaking. … However, reviews of evidence should not be construed to represent clinical recommendations or guidelines … Management of T1DM and T2DM involves clinical care and enabling patients to adopt self-management behaviors … diabetes-behavioral-programs https://www.effectivehealthcare.ahrq.gov/diabetes-behavioral-programs Overview of Clinical … Eisenberg Center for Clinical Decisions and Communications Science at Baylor College of Medicine, Houston

473. TND-0775-150722 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
     May 12, 2015 - Summary: comparative effectiveness of treatments for schizophrenia would inform development of clinical … practice guidelines aimed at optimizing clinical interventions and patient outcomes for individuals … potentially-relevant randomized controlled trials (RCTs) and more than 1,300 ongoing and completed clinical … RCTs (the majority focused on antipsychotic-related weight gain) and nearly 80 ongoing and completed clinical … systematic reviews, more than 500 potentially-relevant RCTs, and more than 300 ongoing and completed clinical

474. celiac-disease-protocol-140612 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
     June 12, 2014 - Clinical signs of CD include aphthous ulcers, low bone density, dermatitis herpetiformis, and other … The lead investigator or clinical expert will resolve any disagreements. … ACG clinical guidelines: diagnosis and management of celiac disease. … National Institute for Health and Clinical Excellence (NICE). … National Institute for Health and Clinical Excellence (NICE). London (UK): 2009 May. 10.

475. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
     February 25, 2016 - However, in clinical practice, the GCS is often used for field assessment of any traumatic injury, and … However, information on clinical outcomes is often lacking and decisions about their use must often … decisionmaking and clinical outcomes. … How do effects on clinical outcomes vary according to patient age or other patient characteristics ( … Key Question 3 addresses the impact of the tGCS compared with the mCGS on clinical outcomes.

476. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
     January 01, 2009 - Algorithmic challenges exist with this disease, and clinical consultation suggests there is a high degree … of variation in clinical practice for the treatment and management of Crohn’s disease. … Clinical practice guidelines based on systematic reviews of the literature are limited, and no guidelines

477. Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0594-131115.pdf
     March 13, 2013 - disabilities (DD/ID) or autism spectrum disorder (ASD) in children and is interested to know the clinical …  Diagnosis of children with DD/ID or ASD can often be made based upon the clinical history and physical … Most of the evidence looks at diagnostic yield, not clinical outcomes.

478. Geographic Variation in Carotid Endarterectomy and Carotid Stenting Among Medicare Beneficiaries, 2003-2006 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cardiology-health-outcomes_research.pdf
     July 01, 2010 - health care providers, patients, and policymakers seeking unbiased information about the outcomes, clinical … Curtis, Ph.D.b,c,d aDuke Clinical Research Institute, Duke University School of Medicine, Durham, … NC bDepartment of Medicine, Duke University School of Medicine, Durham, NC cCenter for Clinical and … Genetic Economics, Duke University School of Medicine, Durham, NC dCenter for Clinical Health Policy … Unmeasured clinical variables may also confound the relationship between observed covariates and the

479. Antiplatelet-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
     September 01, 2013 - Clinical Outcomes Several clinical outcomes of interest were reported: all-cause mortality, cardiac … Clinical Outcomes Six studies (reported in seven publicationsc) provided clinical outcome information … Clinical Outcomes Clinical-outcome comparisons between the randomized treatment groups were reported … for the component clinical events … outcomes in large well-conducted clinical trials.

480. psychiatric-readmissions-protocols-140904 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psychiatric-readmissions_research-protocol.pdf
     December 31, 2014 - The site currently contains approximately 12,400 clinical studies sponsored by the National Institutes … • WHO International Clinical Trials Registry Platform: This platform is a network of international … clinical trials registers to ensure a single point of access and the unambiguous identification of … Assessing clinical predictions of early rehospitalization in schizophrenia. … National clinical survey. Br J Psychiatry. 2006 Feb;188:129-34. Epub: 2006/02/02.