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effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - ,
but clinical trials and observational studies could not be pooled
together. … The clinical aim is NO seizures and NO side
effects. … PHB produced greater clinical worsening on
the MMSE compared to LTG (p<.05). … ADAS-COG: LEV
produced clinical improvement over 12 months while there was a
worsening with PHB and … This is not a
clinical guideline, this is an evidence report.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
October 01, 2015 - This summary is provided to assist in informed
clinical decisionmaking. … However, reviews of evidence should not be construed to represent clinical
recommendations or guidelines … However, current clinical practice in the care of adults with
HF after hospitalization varies greatly … Clinician Research Summary
Clinical Bottom Line
Table 2: Summary of Key Findings and Strength of … Eisenberg Center for Clinical
Decisions and Communications Science at Baylor College
of Medicine, Houston
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-intro.ppt
June 01, 2012 - The context often affects sensitivity, specificity, and the clinical implications of a particular test … Context affects sensitivity, specificity, and the clinical implications of a particular test result. … Most of the published literature:
Fails to address the clinical impact of tests. … Medical tests have several steps between conducting the test and determining the outcome of clinical … When examining outcomes following a medical test, consider any relevant clinical outcomes, including
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-intro.ppt
June 01, 2012 - The context often affects sensitivity, specificity, and the clinical implications of a particular test … Context affects sensitivity, specificity, and the clinical implications of a particular test result. … Most of the published literature:
Fails to address the clinical impact of tests. … Medical tests have several steps between conducting the test and determining the outcome of clinical … When examining outcomes following a medical test, consider any relevant clinical outcomes, including
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
June 01, 2012 - What is the potential clinical utility of the test? … Methodology perspectives: clinical practice guideline development. … Provide further clinical context of the topic. … All of the following are elements of clinical context except:
Patient characteristics
Clinical setting … To understand the range of potential clinical utility.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
June 01, 2012 - What is the potential clinical utility of the test? … Methodology perspectives: clinical practice guideline development. … Provide further clinical context of the topic. … All of the following are elements of clinical context except:
Patient characteristics
Clinical setting … To understand the range of potential clinical utility.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
August 01, 2014 - The following clinical vignette highlights some of the
clinical diagnostic dilemmas: The patient is … What is the clinical significance
of his newly elevated troponin? … Only one study compared discrimination against a
model of clinical factors. … Clinical performance of two
highly sensitive cardiac troponin I assays. … National Academy of
Clinical Biochemistry Laboratory Medicine Practice Guidelines:
clinical characteristics
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
September 01, 2011 - An expanded discussion of the clinical implications of the main findings
might increase the value of … the report to clinical readers. … It is clear from both the
report and from clinical experience that off-label use of atypicals is not … Reviewer 3 Methods
The clinical descriptions and definitions are clear and accurate. … A clinical rationale for these
decisions should be provided or separate analyses should be presented
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0262_05-11-2007.pdf
January 01, 2007 - Does this make a clinical difference in response to treatment?
8. … Do any of the following have evidence of clinical benefit in the treatment of patients
with incontinence … Are there clinical predictors of response to the (above) interventions? … What is the evidence to support specific clinical interventions to reduce the risk of urinary and fecal
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
April 01, 2014 - Clinical Evidence, UpToDate, and eMedicine scored highest on
editorial quality. … To compare PubMed Clinical Queries
and UpToDate in teaching information mastery
to clinical residents … Results availability from clinical research of
female urinary incontinence. … Results availability from
clinical research of female urinary incontinence. … Results availability from clinical
research of female urinary incontinence.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
June 01, 2013 - review, we searched for ongoing clinical
trials of these technologies in stage I NSCLC. … practice in the absence of direct comparative clinical trial
evidence to support its reputation of … clinical superiority
over conventionally fractionated conformal techniques. … Proton therapy in lung
cancer: clinical outcomes and technical issues. A systematic
review. … Palliative care in lung cancer:
ACCP evidence-based clinical practice guidelines (2nd edition).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - Rather, as described above, we searched for unpublished
studies through searches of clinical trials … Implications for Clinical and Policy
Decisionmaking
Our review has important implications for clinical … Clinical J Pain.
2008;24(6):469-478. PMID: 18574357.
4. … Clinical guidelines
for the use of chronic opioid therapy in chronic noncancer
pain. … Users’ guides
to the medical literature: XXII: how to use articles about
clinical decision rules.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0543_05-24-2013.pdf
January 01, 2013 - Existing clinical guidelines
recommend against routine antibiotic use for ACI in otherwise healthy adults … The conclusions in the most recent clinical trials
note that a decrease in antibiotic use was associated … this topic can be used to inform
provider and patient education strategies, practice guidelines, and clinical
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/future-research-prioritization-methods_research.pdf
January 01, 2013 - This report is not intended to
be a substitute for the application of clinical judgment. … Anyone who makes decisions concerning
the provision of clinical care should consider this report in … benefits and potential clinical harms.
6 Represents important variation in clinical care or controversy … To reduce significant variation in clinical practices known to be related to quality of care. … For any given clinical topic, the relative value of the criteria may differ from another
clinical topic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
January 01, 2011 - Figure 1 is a
superb visualization of the pathways involved in iron
metabolism and related clinical … Key Question 4 addresses the factors that may affect test
performance and clinical utility of newer … Before we conducted the CER, clinical experts were
reconvened to form the Technical Expert Panel (TEP … Testing needs are different
when clinical question is too much versus too little iron. … Testing needs are different when clinical question is too
much vs. too little iron.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
September 01, 2012 - Prospective; clinical practice. … Setting Prospective; clinical practice. Prospective; clinical practice. … o Incorporates issues around both clinical benefits and potential clinical harms. … Prospective; clinical practice. … Setting Prospective; clinical practice. Prospective; clinical practice.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - outcomes in large, well-conducted clinical trials. … We clearly need more data in terms of well-
designed clinical trials. … None of these assays are surrogate
for in vivo clinical event occurrence- ie thrombosis. … This study reported no clinical events in
both arms, again making the NNG uninformative. … We cannot assess the “value” of specific interventions or
clinical practices.
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effectivehealthcare.ahrq.gov/sites/default/files/analytic-frameworks.ppt
December 09, 2009 - A type of evidence model that links and defines clinical concepts, evidence, and populations as they … To provide clinical, biological, or health services underpinnings for the mechanism of action
To clarify … Comparators and clinical decision points may be included in an analytic framework, but are more often … Developing evidence-based clinical practice guidelines: lessons learned by the US Preventive Services … Developing evidence-based clinical practice guidelines: lessons learned by the US Preventive Services
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effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
January 01, 2012 - Drafts of those reports are sent to various experts with clinical, health systems, health administration … (External, Clinical). Horizon
Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
August 18, 2011 - Stress management
The specific medications will vary by clinical condition. … Biomarkers of clinical outcomes
b. … Clinical outcomes (mortality, morbidity measures defined by the clinical condition)
Source: www.effectivehealthcare.ahrq.gov … The awareness-to-adherence model of the steps to
clinical guideline compliance. … Clinical Guideline No. 76.
18. New York State Department of Health.