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401. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
     October 01, 2007 - Most randomized controlled clinical trials (RCTs) of angioplasty and surgery have been conducted in this … In large clinical registries, comparative survival after PCI or CABG varied significantly according to … In analyses from large clinical registries of patients with middle spectrum CAD severity, there was no … the outcomes of patients according to their clinical presentation. … Comparative effectiveness by clinical presentation Clinical presentation Acceptable - Reported by 3

402. Disposition of Comments for Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
     January 01, 2012 - Given clinical heterogeneity and limited head to head comparisons, the evidence limits our ability to … Finally we added this sentence to the summary of the findings of this study for clinical events on page … In comparison, SBPM may be a simpler intervention to introduce in the clinical setting.” … We added “race and ethnicity” We decided to de-emphasize this given the clinical heterogeneity for … However, there is an entire section on “Sources of clinical heterogeneity” in the discussion section

403. Omega−3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
     August 01, 2016 - Clinical Event Outcomes, RCTs No RCTs reported clinical event outcomes for comparisons of total n-3 … Clinical Event Outcomes, RCTs Regarding clinical event outcomes, 19 trials in populations at increased … Clinical Event Outcomes, RCTs Regarding clinical event outcomes, one trial in an at risk population … Clinical Event Outcomes, RCTs No trial that reported clinical event outcomes evaluated DHA alone. … Clinical Event Outcomes, RCTs No trial that reported clinical event outcomes compared marine oil FA

404. Back (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back.pdf
     January 01, 2011 - Back Slide  1: Decision making  when clinical … for… o 1% chance of cure Source: Eisenberg  Center Conference Series 2011,  Differing Levels of Clinical … options remained  open Source: Eisenberg  Center Conference Series 2011,  Differing Levels of Clinical … QOL as long as possible Source: Eisenberg  Center Conference Series 2011,  Differing Levels of Clinical … Source: Eisenberg  Center Conference Series 2011,  Differing Levels of Clinical Evidence: Exploring

405. What do we know about how evidence of harm and benefit is communicated in other countries? (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
     January 01, 2005 - Eisenberg Clinical Decisions and Communications Science Center Oregon Health & Science University … available in print or web-based format Related to an evidence review with or without an associated clinical … Canada and New Zealand Canada Clinical Practice Guidelines for Diagnosis and Management of Osteoporosis … Musculoskeletal Pain (2003) Acute Low Back Pain United Kingdom National Institute for Health and Clinical … consumers contains background info, going beyond the systematic evidence review Other countries develop clinical

406. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
     January 01, 2007 - antiplatelet, and antilipid treatment) compared to renal artery angioplasty with stent placement on long-term clinical … What are the patient characteristics, including etiology, predominant clinical presentation, and severity … What clinical, imaging, laboratory, and anatomic characteristics are associated with improved or worse … • Weak or inconsistent evidence does not support statements on whether other clinical features (such … indicators of RAS severity) or diagnostic tests predict whether patients would 3 have better clinical

407. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - Nominator(s): Health care professional association Nomination The nominator asserts that there is clinical … in children with chronic otitis media with effusion (OME) at different thresholds of frequency of clinical … tubes in children with recurrent acute otitis media (AOM) at different thresholds of frequency of clinical … In consultation with a clinical reviewer, the Key Questions were revised in order to examine the comparative … benefits, or moderate benefits of similar magnitude to antibiotic prophylaxis. § We identified a clinical

408. pediatric-EHR-protocol-140818 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-ehr_research-protocol.pdf
     January 01, 2014 - Key Informants will help to identify key issues related to definitions, clinical areas, population, … Examples of sources of grey literature include government websites, clinical trial databases, trade … Impact of clinical alerts within an electronic health record on routine childhood immunization in an … Clinical benefits of electronic health record use: national findings. … Electronic health records, clinical decision support, and blood pressure control.

409. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Those reports are sent to various experts with clinical, health systems, health administration, and/or … practice, clinical research, health care delivery, health business, health technology assessment, … Experts are identified in the system by the perspective they bring (e.g., clinical, research, health … Results and Discussion of Comments Six experts with clinical, research, health systems, and health … (External, Clinical). Horizon Scanning Structured Comment Form.

410. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
     January 01, 2012 - (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (PRI, Clinical). Horizon Scanning Structured Comment Form. … (PRI, Clinical). Horizon Scanning Structured Comment Form.

411. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - Modeling studies were excluded as they do not assess actual clinical data. … Clinical Infectious Diseases. 2011;53(8):780–786. … Moreover, your analysis only considered randomized clinical trials. … have evaluated clinical effects of rapid testing on test uptake or clinical outcomes. … There are as yet no clinical data from the CDC study.

412. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - This study is an extension of a phase III, clinical trial (CONQUER). … Institute for Clinical Systems Improvement (ICSI). … (PRI, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form.

413. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
     January 01, 2012 - Those reports are sent to various experts with clinical, health systems, health administration, and/or … practice, clinical research, health care delivery, health business, health technology assessment, … Experts are identified in the system by 2 the perspective they bring (e.g., clinical, research … The ASD clinical pathway is complicated, however, by the subjective nature of diagnosis, which relies … Significant clinical opposition to its use exists because of its potential risks to children and a

414. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - Those reports are sent to various experts with clinical, health systems, health administration, and/or … context in which these new and evolving interventions exist to understand their potential impact on clinical … practice, clinical research, health care delivery, health business, health technology assessment, or … Experts are identified in the system by the perspective they bring (e.g., clinical, research, health … U.S. and European investigators are leading phase II and II/III clinical trials studying intranasal

415. Decision Modeling (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
     June 01, 2012 - AD in Long-term Clinical Evaluation No AD in Long-term Clinical Evaluation PET suggestive of AD “True … exam and not as a replacement for the typical clinical exam. … Test [Clinical exam or clinical exam and PET] Treat if test is positive [with AChE-I] Those with … Here, the use of a clinical exam is being compared to the use of a clinical exam plus PET during the … , as performance of the test itself is not a direct clinical outcome.

416. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - Table 1 outlines the antiplatelet and anticoagulant therapies available for each clinical scenario: … Current clinical practice regarding the dose and timing of oral P2Y12 treatment varies dramatically. … While there is a well-established body of clinical evidence supporting the use of GP IIb/IIIa agents … Despite the recent clinical data assessing anticoagulant therapy, a number of questions still remain … trial[pt] OR "clinical trial"[tw] OR "clinical trials"[tw] OR "evaluation studies"[Publication Type

417. Decision Modeling (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
     June 01, 2012 - AD in Long-term Clinical Evaluation No AD in Long-term Clinical Evaluation PET suggestive of AD “True … exam and not as a replacement for the typical clinical exam. … Test [Clinical exam or clinical exam and PET] Treat if test is positive [with AChE-I] Those with … Here, the use of a clinical exam is being compared to the use of a clinical exam plus PET during the … , as performance of the test itself is not a direct clinical outcome.

418. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
     July 01, 2012 - of patients, clinical practices, and prognostic groups? … Clinical outcomes: Would use of the prognostic test improve patient outcomes? 6. … Did the sample represent patients that would be tested in clinical practice? 4. … A review of these types of studies would have limited clinical value. … The importance of disease prevalence in transporting clinical prediction rules.

419. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Objectives for the Systematic Review Sepsis is a condition with high morbidity and mortality in which clinical … The following Key Clinical Questions and Analytic Framework outline the approach and key issues to … No changes were made to the key clinical questions based on the public comments. … Procalcitonin for the clinical laboratory: a review. Pathology 2007;39(4):383-90. 10. … Technical Experts Technical Experts comprise a multi-disciplinary group of clinical, content, and

420. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - Those reports are sent to various experts with clinical, health systems, health administration, and/or … Experts offered different perspectives about potential patient and clinical acceptance. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form. … (External, Clinical). Horizon Scanning Structured Comment Form.