-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
September 23, 2014 - We did revise
the report to be clearer about the clinical
implications. … This is out of clinical context. One cannot
operate on EUS-FNA alone. … We did revise
the report to be clearer about the clinical
implications. … the
appropriate scans to be used for specific clinical indications. … Our goal was to uncover evidence to support
clinical actions such as the ones you listed.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
January 01, 2009 - Even in carefully controlled clinical trials, it is difficult to
ensure that every patient takes all … of their medications as prescribed, and adherence rates are much
lower in ordinary clinical practice … including a review from the
Cochrane group and guidelines issued by the National Institute for Health and Clinical … Clinical Guidelines and Evidence Review for Medicines Adherence: involving
patients in decisions about … NICE and Cochrane did not identify any interventions that appear
practical to implement into current clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - Thank you
TEP Reviewer
#1
General The review is a useful guide to clinical management of
ARAS … problem with a suboptimal database from
which to make clinical recommendations. … equipoise” that
drives enrollment in clinical trials is completely different
than clinical indications … Clearly future
clinical trials are needed in this patient population. … Its best to
have primary care physicians know the full picture on
this vital clinical area.
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - trial
and an NKFsponsored clinical practice guideline that
both favor tacrolimus as the first line … The Kidney Disease Improving Global Outcomes
KDIGO 2009 clinical practice guideline on the Care of … for clinical practice. … End-
users must weigh the
benefits and harms in
making decisions about
clinical care. … The
section on clinical/policy decision making was well
done.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
June 24, 2014 - More specifically, the nominator is
interested in the diagnostic accuracy of clinical criteria alone … baseline uric acid levels for determining the
effectiveness of treatment on intermediate and final clinical … Staff-Generated PICO
Population(s): Adults with or at risk of having gout
Intervention(s): Clinical … What is the accuracy of clinical criteria only in the diagnosis of acute gouty
from Nominator: arthropathy … However, some studies indicate that diagnosis in primary care is often based
primarily on clinical signs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - Outcomes 5O: Almost no data on clinical outcomes. … Outcomes 5O: Almost no data on clinical outcomes. … Clinical outcomes of interest would include incident
clinical events, quality of life, and psychological … Incorporates issues around both clinical benefits and potential clinical harms
2f. … Represents important variation in clinical care, or controversy in what constitutes
appropriate clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
January 01, 2014 - A recent clinical
trial (Schiffmann et al. … A key clinical study in children under 6 years of age with
idursulfase is omitted
‐ A clinical study … A recent clinical trial (Schiffmann et al. … and clinical outcomes for a
few LSDs. … Chaperone therapy clinical trials.
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - Clinicians use the prothrombin time and INR as clinical
tools to guide anticoagulation therapy. … For a
clinical prediction rule, we assumed that a c-statistic <0.6
had no clinical value, 0.6–0.7 had … clinical risk
of patients, combining both their risk of stroke and their
risk of bleeding? … There is also a need for future
studies in special populations and clinical scenarios. … Meta-analysis in clinical trials. Control
Clin Trials. 1986;7(3):177-88. PMID: 3802833.
39.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
October 01, 2015 - The cost of hands-on clinical training for the OCS Lung was $100,000,
and clinical field support 24 … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
April 01, 2019 - • Long-term oral hormone therapies reduce hip
and clinical fractures but increase multiple serious … trial; CF=clinical
fracture; CI=confidence intervals; CVF=clinical vertebral fracture; h-IM=highly … Our findings have several clinical implications. … American
Association of Clinical Endocrinologists Medical
Guidelines for Clinical Practice for the … Safety assessment
of raloxifene over eight years in a clinical trial setting.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
November 20, 2013 - Journal of Clinical Epidemiology 57:925-932. … The clinical context has been described as recommended
in current clinical practice guidelines. … context in light of the
clinical practice guidelines. … Journal of Clinical Epidemiology 57:925-932. … Journal of Clinical Epidemiology 57:925-932.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
October 01, 2012 - Executive Summary
Background
Sepsis is a serious condition with high
morbidity and mortality for which clinical … units (ICUs) have higher
morbidity and mortality rates, the same
issues are also relevant to other clinical … Again, the
duration of antibiotic therapy is often
undefined, and clinical features are of
limited … Comparator: Initiation, discontinuation, or intensification
of antibiotic therapy guided by clinical … Experience with a clinical
guideline for the treatment of ventilator-associated pneumonia.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - and laboratory features into risk scores
to help in clinical decisionmaking.5-8 Nomograms are intended … Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and
improved … of life, and the potential clinical and personal harms of PCA3 testing and/or related
intervention … Testing complies with requirements of the Clinical Laboratory Improvement
Act (Public Law 100-578). … In the indirect chain of evidence, Link B addresses
the diagnostic accuracy (clinical validity) of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - Background
Meditation is used widely by both clinical populations and the general public to treat … the
meditation programs on clinical populations. … outcomes of pain and
weight among those with a clinical condition. … Due to the need to limit scope, we have also focused on clinical populations. … settings Clinical settings General and clinical settings Clinical settings
Adverse
effects of
intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - This search includes regulatory documents and conducted clinical trials. … and WHO Clinical Trials (International). … Osteoarthritis: national clinical
guideline for care and management in adults. … Clinical practice. Osteoarthritis of the knee. N Engl J Med 2006;354:841-8.
24. … Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88.
46. Ebrahim S.
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - Whereas participants in
randomized clinical trials (RCTs) of drugs sometimes fail to
represent the full … Supports study designs that incorporate linkages to other sources of clinical, contextual
and outcome … Linkages to external sources of clinical information may be possible in some studies. … Variable construction should be informed by clinical understanding of relevant
conditions, treatments … Adapting a clinical comorbidity index
for use with ICD-9-CM administrative databases.
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Those reports are sent to various experts with clinical, health systems, health administration, and/or … practice, clinical research, health care delivery, health
business, health technology assessment, … Pharmacy clinical policy bulletins. … (External, Clinical).
Horizon Scanning Structured Comment Form. … (External, Clinical).
Horizon Scanning Structured Comment Form.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-provider-adherence_research-protocol.pdf
March 02, 2012 - Clinical
Figure 1. … Reviewer pairs
will be formed to include personnel with both clinical or domain, and methodological … Why don't physicians follow clinical practice guidelines? A
framework for improvement. … Meta-analysis in clinical trials. Control Clin Trials 1986; 7(3):177-88.
37. … Journal of clinical epidemiology, 2010. 63(5): p. 513-23.
V.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - Although this summary provides a review of evidence, it should
not be construed to represent clinical … and physician
perception of patient expectations; clinician specialty,
knowledge, and experience; clinical … Interventions include clinical strategies
(e.g., use of point-of-care diagnostic tests, delayed antibiotic … Clinical Interventions (Point-of-Care Testing):
��Procalcitonin point-of-care testing in adults reduced … Clinical Interventions (Delayed Versus Immediate
Prescribing):
��Delayed prescribing of antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Recent clinical trials have demonstrated the
efficacy of three medications—tamoxifen
citrate, raloxifene … Current
clinical recommendations, including those
from the U.S. … The review also examines issues related to clinical
effectiveness, such as patient choice, concordance … What methods, such as clinical
risk-assessment models, have been used to identify
women who could benefit … trials, it is not clear which women in clinical
practice would optimally benefit from risk reduction