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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - While mainly used for hemophilia and related conditions, off-label use of rFVIIa has increased in the … pageaction=displayproduct&productID=450
Chronic prophylactic use in hemophilia A and B
Episodic use … Chronic prophylactic use in hemophilia A and B in the absence of bleeding episodes or procedures. … efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation due to chronic … surgery), obstetrical conditions, primary clotting disorders (other than hemophilia), pulmonary conditions
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - In
reality, many individuals who participate in registries, such as those with chronic, lifelong
illnesses … Alliance established the Genetic Alliance Registry and BioBank to
support research across a range of conditions … of
obtaining regulatory approvals for new indications of marketed products, particularly for rare
conditions … For example, a
French group was able to gather data from over 600 participants living with chronic illness … Online social
networks-based qualitative research to
identify participant-relevant concepts in
chronic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - They found that fluctuating or intermittent conditions are much more
difficult to assess with observational … When different diagnoses, severity of illness, or comorbid conditions are
important reasons for physicians … Outcomes such as exacerbations or relapses of chronic diseases, serious adverse
events, or major changes … patients who meet symptomatic and echocardiographic or angiographic criteria for
moderate or severe chronic … Thus, at baseline, the patients in the carvedilol group are more likely to have severe, chronic
symptomatic
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effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - They found that fluctuating or intermittent conditions are much more
difficult to assess with observational … When different diagnoses, severity of illness, or comorbid conditions are
important reasons for physicians … Outcomes such as exacerbations or relapses of chronic diseases, serious adverse
events, or major changes … patients who meet symptomatic and echocardiographic or angiographic criteria for
moderate or severe chronic … Thus, at baseline, the patients in the carvedilol group are more likely to have severe, chronic
symptomatic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
May 01, 2013 - systematic
appraisals of existing scientific
evidence regarding treatments for
high-priority health conditions … colectomy; however, most clinicians
reserve colectomy for patients with the most terminal or
untreatable conditions … Pathophysiology, diagnosis and current management
of chronic constipation. … Systematic review on
the management of chronic constipation in North America. … Diagnosis and
treatment of chronic constipation--a European perspective.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
March 22, 2016 - Mental Disorders (DSM-4) used the dementia
terminology, the 5th edition (DSM-5) calls these types of conditions … Certain medical conditions are associated
with an increased risk of developing MCI and Alzheimer’s disease … , including depression,
cancer, cardiovascular disease, diabetes, delirium, thyroid disorders, chronic … Interventions have
been developed to address chronic disease status, modifiable risk factors as well … Examples include treatment and control of chronic medical
or mental health conditions (i.e., cardiovascular
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effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - The treatment of unrelated disorders in patients with chronic medical diseases. … effectiveness research aims to compare benefits and harms of different interventions in real-world conditions … Being selected for surgeries or procedures may be a surrogate for better general physical conditions … including having less severe disease and comorbid conditions and better functional and psychological … not provide information on the actual intake of medications by patients, and most drug exposure is chronic
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
April 20, 2022 - affect up to 10 percent of pregnancies, and
encompass a spectrum of disorders that include preexisting chronic … work, different levels of social support, and other structural effects of systemic racism (such as
chronic … HDP subgroup, maternal
age, parity, singleton/multiple pregnancies, mode of delivery, co-occurring conditions … HTN
o gestational HTN
o preeclampsia (may be superimposed on chronic HTN)
o preeclampsia with severe … different subgroups, including by race/ethnicity, maternal and pregnancy characteristics, co-
occurring conditions
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - Obsessive-compulsive disorder (OCD) is a chronic condition
characterized by obsessions (repetitive thoughts … Moreover, the addition of several conditions of interest will
expand the scope. … Conditions!
!!!
4.! Across!all!conditions!of!interest,!what!are!the!harms!of!first!and!second! … KQ3 will evaluate harms across all conditions. … Adjunctive risperidone treatment for
antidepressant-resistant symptoms of chronic military service-related
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effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
March 29, 2012 - Patients with certain chronic diseases or patients
who take many medications may also have a
lower … likelihood of treatment.11
Due to these findings, researchers have
recommended statin use and other chronic … The
disjunctive cause criterion is a formal statement of
the conditions in which variable selection
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Professional organizations widely endorse anticoagulants for preventing and treating
blood clots in conditions … that have a higher risk of leading to venous thromboembolism
and stroke (e.g., chronic atrial fibrillation … Professional organizations widely endorse anticoagulants for preventing and treating blood clots in conditions … that have a higher risk of leading to venous thromboembolism and stroke (e.g., chronic atrial fibrillation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - If none of these conditions are met, the additional data are unlikely to
directly impact the strength … : What is the effectiveness of tympanostomy tubes, compared to watchful
waiting, in children with chronic … o Sociodemographic risk factors
KQ 1: Children with chronic OME (allow study-specific definitions of … “chronic”
but use as a standard definition effusion that persists for 3 months or
longer1)
KQ 2: … Children at high risk of chronic
otitis media or recurrent acute otitis media have been excluded from
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - assessments provide organizations
with comprehensive, science-based information on common, costly medical conditions … • Size of the pool of potential subjects: Some conditions may be relatively uncommon, or
the subpopulation … a specific clinical condition, such as hypertension, has significant clinical
overlap with related conditions … When the outcomes of interest are
common to all conditions (e.g., medication side effects, quality of … life) then meta-analysis across
clinical conditions may provide additional useful information.
-
effectivehealthcare.ahrq.gov/sites/default/files/mccormack-presentation.pdf
May 29, 2025 - our most vulnerable
populations -‐-‐ the elderly, chronically ill, and those with co-‐occurring conditions … More clinical conditions are becoming available online;
more evidence is becoming contradictory, and
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-foot-ulcer-amputation-prevalence_research.pdf
February 01, 2011 - amputation vary by geographic location.3
Diabetic foot ulceration can develop because of acute or chronic … will primarily display peripheral neuropathy, and about 30
percent will display a combination of both conditions … This report was limited because
it did not include outpatient care or chronic care facilities, may … Any
beneficiary with diabetes as defined above and a venous leg ulcer code, another
common chronic
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Left untreated, chronic GERD can cause bleeding and ulceration of the
esophageal lining. … for patients with a diagnosis of GERD “as defined by abnormal pH testing, and
who continue to have chronic … Left untreated,
chronic GERD can cause bleeding and ulceration of the esophageal lining. … without damage to the esophageal lining (esophagitis), clinicians
classify it as GERD.3 Left untreated, chronic … Additionally, medical
advances are now allowing children with conditions that put them at risk of SBS
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - report Comparative Effectiveness and
Safety of Analgesics for Osteoarthritis.1
Osteoarthritis is a chronic … Opioid medications are also used for selected
patients with refractory, chronic pain but are not recommended … • Capsaicin cream relieves chronic osteoarthritic pain, but about half of the people
using it will … • Demographic subgroups: age, sex, and race
• Coexisting diseases: cardiovascular conditions, such … August 05, 2010
pleurisy; systemic lupus
erythematosus; rheumatoid
arthritis; stable angina,
chronic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
May 01, 2013 - assessments provide organizations
with comprehensive, science-based information on common, costly medical conditions … Systematic review on the management of
chronic constipation in North America. … therapy.10 Most clinicians reserve colectomy for patients with the most terminal or untreatable
conditions … Systematic review on the management of
chronic constipation in North America. … Diagnosis and treatment of chronic
constipation--a European perspective.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - Health Care Program
2
improve without treatment in 1 year, 10 percent to
20 percent develop a chronic … • Different PTSD symptoms
• Complex PTSD
• Chronic PTSD
• Exposure to childhood trauma … Paroxetine in the treatment of chronic posttraumatic stress disorder: results of a placebo-controlled … Most studies
included participants with chronic PTSD. … A guide to guidelines for
the treatment of PTSD and related conditions.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
July 29, 2014 - : ACP for relatively
healthy individuals; ACP for the individual with an established
condition or conditions … that are manageable; ACP for the
individual with serious, advanced conditions. … end-of-life
decisions because ACP requires people to imagine what life
would be like under various conditions … and priorities
should now include more detail about one’s goals of care specific
to the person’s chronic … Educational components can
be tailored to differing chronic conditions or combinations of
conditions