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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Chronic pelvic pain study characteristics
Author, Year
Country
Trial Name
Quality Rating Type(s) of … N Randomized
N Analyzed Intervention Duration (Weeks) Funding Source
AbdelHafeez, 2019
Egypt
Fair Chronic … GaPP2
Good Chronic pelvic pain Age, mean: 30.3
Female: 100%
Race:
White: 97%
Black: 0.3%
Asian: 2%
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Weight Gain: N N Randomized Blurred vision: n Blurred vision: N N Randomized
Abdelhafeez, 2019 Fair Chronic … concentration 3 30 30 NR NR NR Somnolence 3 30 30 8 30 30 NR NR NR NR NR NR
Abdelhafeez, 2019 Fair Chronic … NR NR NR NR NR NR Tired 85 129 153 66 122 153 NR NR NR 25 113 153
Horne, 2020 and Hewitt, 2020 Good Chronic … NR NR NR NR NR NR Tired 68 120 153 32 114 153 NR NR NR 12 110 153
Horne, 2020 and Hewitt, 2020 Good Chronic … NR NR NR NR NR NR NR Drowsy 64 124 153 NR NR NR NR NR NR NR NR NR
Horne, 2020 and Hewitt, 2020 Good Chronic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - NR Poor concentration 3 30 30 NR NR NR Somnolence 3 30 30 8 30 30 NR NR NR
Abdelhafeez, 2019 Fair Chronic … concentration 1 30 30 NR NR NR Somnolence 1 30 30 1 30 30 NR NR NR
Horne, 2020 and Hewitt, 2020 Good Chronic … NR NR NR NR NR NR NR NR NR Tired 85 129 153 66 122 153 NR NR NR
Horne, 2020 and Hewitt, 2020 Good Chronic … NR NR NR NR NR NR NR NR NR Tired 68 120 153 32 114 153 NR NR NR
Horne, 2020 and Hewitt, 2020 Good Chronic … NR NR NR NR NR NR NR NR NR NR Drowsy 64 124 153 NR NR NR NR NR NR
Horne, 2020 and Hewitt, 2020 Good Chronic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Chronic pelvic pain study characteristics
Author, Year
Country
Trial Name
Quality Rating Type(s) of … N Randomized
N Analyzed Intervention Duration (Weeks) Funding Source
AbdelHafeez, 2019
Egypt
Fair Chronic … GaPP2
Good Chronic pelvic pain Age, mean: 30.3
Female: 100%
Race:
White: 97%
Black: 0.3%
Asian: 2%
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - Maheu, 2022 RCT
Duration: 12 weeks; optional 12 week followup
Multicenter
France Pain condition: Chronic … device, positioning standardized to the neurostimulation method for the treatment of moderate to severe chronic … vs. 72.4%
Black: 16.9% vs. 17.1%
Asian: 10.8% vs. 9.3%
Other: 1.2% vs. 1.2%
Mean (SD) duration since chronic … Duration: 12 month followup Inclusion: Patients with chronic opioid therapy (≥84 consecutive days of … Duration: 12 months Inclusion: Veterans aged ≥18 years with chronic non-cancer pain receiving chronic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - Poor
van de Donk, 2020 RCT
Duration: 3 months Pain clinic
Netherlands Pain condition: Nonspecific chronic … 2020 Retrospective cohort study; VA
United States
Duration: 12 months Veterans aged ≥18 years with chronic … non-cancer pain receiving chronic non-parenteral opioid therapy for ≥2 consecutive 180-day periods between … D 12 months prior to cohort entry to end of followup, no history of cancer, and ≥2 claims for mixed chronic … 18.8%
Female: 66.2%
Race/ethnicity
White: 80.8%
African American: 8.2%
Latino: 6.1%
Other: 4.8%
≥ 1 chronic
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effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
April 16, 2020 - Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain
Comparative … Nonopioid Pharmacologic Treatments for Chronic Pain. Comparative
Effectiveness Review No. 228. … All three chronic pain reports
used the more recent MMWR paper. … on Nonopioid Pharmacologic Treatments for
Chronic Pain. … https://effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/research
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-fatigue_executive.pdf
July 01, 2016 - Contrasting chronic fatigue
syndrome versus myalgic encephalomyelitis/chronic fatigue
syndrome. … Contrasting case definitions
for chronic fatigue syndrome, myalgic encephalomyelitis/chronic
fatigue … Stigma and chronic fatigue
syndrome. J Chronic Fatigue Syndr. 1999;5(2): 63-95.
43. … Diagnosis in chronic illness:
disabling or enabling--the case of chronic fatigue syndrome. … fatigue or chronic
fatigue syndrome.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
January 07, 2013 - Peer Reviewer #2 General Unexplained or idiopathic cough (chronic) is a focal point of
chronic cough … workup are considered to have
unexplained chronic cough. … at
diagnosing and treating the root causes of the chronic cough. … Text regarding the prevalence of
chronic cough worldwide has been
added. … workup are considered to have
unexplained chronic cough.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - pain, and clinicians who treat chronic pain. … of chronic pain? … of chronic pain? … Prevalence of chronic pain and high-impact chronic pain among adults
— United States, 2016. … Efficacy of opioids for chronic pain: a review of the evidence.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-surveillance-report-1-updated_0.PDF
December 01, 2021 - Pain
1
Living Systematic Review on Cannabis
and Other Plant-Based Treatments for
Chronic Pain … for treatment of chronic pain? … KQ2: In adults with chronic pain, what are the harms of cannabinoids for
treatment of chronic pain? … treatment of chronic pain? … of chronic pain?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Pain severity for chronic pelvic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 … Pain response for chronic pelvic pain
Author, Year Quality Pain Population Drug Class Drug Response … Criteria Assessment Time (Wk) Time Category n Responder N N Randomized
AbdelHafeez, 2019 Fair Chronic … 2700 mg ≥30% reduction on VAS (0-10) from baseline 24 Intermediate 19 20 30
AbdelHafeez, 2019 Fair Chronic … Function outcomes for chronic pelvic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Poor
van de Donk, 2020 RCT
Duration: 3 months Pain clinic
Netherlands Pain condition: Nonspecific chronic … non-cancer pain receiving chronic non-parenteral opioid therapy for ≥2 consecutive 180-day periods between … race, marital status, rural-urban community area); enhanced Charlson comorbidity score; diagnoses for chronic … D 12 months prior to cohort entry to end of followup, no history of cancer, and ≥2 claims for mixed chronic … 18.8%
Female: 66.2%
Race/ethnicity
White: 80.8%
African American: 8.2%
Latino: 6.1%
Other: 4.8%
≥ 1 chronic
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effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
August 08, 2017 - Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix E
Appendix E. … British Heart Foundation)
Derry, 2016
(Good) To evaluate efficacy and safety of topical NSAIDs for chronic … 6 topical diclofenac vs. carrier, 2 topical diclofenac vs. oral diclofenac Adults (≥16 years) with chronic
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effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
January 01, 2018 - Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix F2
Appendix F2.
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effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apg.xlsx
January 01, 2019 - Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix G
Appendix G.
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effectivehealthcare.ahrq.gov/products/pain-chronic/technical-brief
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effectivehealthcare.ahrq.gov/products/chronic-cough/research-protocol
-
effectivehealthcare.ahrq.gov/products/telehealth-acute-chronic/research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
November 01, 2020 - pain (Opioid Treatments for Chronic Pain, Nonopioid Pharmacologic Treatments for
Chronic Pain, and … The sample was three reviews in a specific topic area (chronic
pain). … (chronic adj2 pain).ti,ab,kw.
3. … Opioid Treatments for Chronic Pain
KQ 1-3 (Treatment)
1. … (chronic adj2 pain).ti,ab,kw.
3.