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effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
January 01, 2013 - Slide 1
Study Size Planning for Observational Comparative Effectiveness Research
Prepared for:
Agency for Healthcare Research and Quality (AHRQ)
www.ahrq.gov
Study Size Planning for Observational Comparative Effectiveness Research
This slide set is based on a user guide titled Developing a Protocol for Observation…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
October 01, 2007 - The choice between PCI and CABG is most relevant
for patients whose coronary artery disease (CAD) lies
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Layout 1
Oral Diabetes Medications for Adults With
Type 2 Diabetes. An Update
Executive Summary
Effective Health Care
Comparative Effectiveness Review
Number 27
Effective
Health Care
Background
Type 2 diabetes is a common chronic
illness characterized by insulin resistance
and eventually by decreased insulin
…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
October 01, 2014 - treatment response
evaluation for metastatic breast cancer, answers ranged from every
2-4 months to choice
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
August 01, 2012 - for nitrous oxide for the management of labor pain
Preference
for Pain
Management
Methods
Choice
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effectivehealthcare.ahrq.gov/sites/default/files/s149.pdf
October 01, 2007 - This
choice can lead to unstable estimates due to small sample
sizes, especially for skewed data such
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
September 01, 2013 - To simplify the choice, an organization may wish to consider the advantages and
disadvantages of creating
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - 1
Comparative Effectiveness Review
Number 65
Interventions for Adolescents and Young
Adults With Autism Spectrum Disorders
Executive Summary
Background
Autism Spectrum Disorders (ASD)
are among the most common
neurodevelopmental disorders, with an
estimated prevalence of 1 in 110 children
in the United Stat…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - In the
former, practitioners move to another therapeutic choice and in the latter,
study subjects drop
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effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
March 29, 2016 - Peer Reviewer #6 Discussion For the testing section there should be some
acknowledgement that the choice … Should that guide our treatment choice?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-212-urinary-incontinence-disposition-comments.pdf
August 08, 2018 - The choice of a P value of 0.05 is
standard, but arbitrary. … We agree that this is not the best choice of comparisons to
make the point about patient preferences
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
July 05, 2011 - information
regarding the lack of randomized trials
making direct comparisons of
techniques to inform choice … Peer Reviewer
#11
Results emotional “turmoil” is not the best word choice;
“burden” might be better … A better word choice would be
“to continuously improve and asses the quality of
outcomes.”
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-disposition-comments.pdf
February 28, 2025 - Our choice of outcomes for this
systematic review was informed
by our conversations with the
Technical
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effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
October 01, 2007 - addition, a collection of less explicit character-
istics of both the patient and prescriber influence the choice
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - assess a body of evidence evaluating diagnostic test outcomes (e.g., diagnostic thinking, therapeutic choice … assess a body of evidence evaluating diagnostic test outcomes—such as diagnostic thinking, therapeutic choice … and transparent system of grading using the discussed domains
Giving an explicit rationale for the choice
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - assess a body of evidence evaluating diagnostic test outcomes (e.g., diagnostic thinking, therapeutic choice … assess a body of evidence evaluating diagnostic test outcomes—such as diagnostic thinking, therapeutic choice … and transparent system of grading using the discussed domains
Giving an explicit rationale for the choice
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
March 01, 2012 - The 3 factors most influencing
their choice of agents: efficacy in reducing VTE risk
(83%), bleeding
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_executive.pdf
September 01, 2012 - The Statin
Choice decision aid in primary care: a randomized trial. … Helping
patients with type 2 diabetes mellitus make treatment
decisions: statin choice randomized trial … Further exploration of the statin
choice randomized trial results. … Use of a decision
aid to improve treatment decisions in osteoporosis: the
osteoporosis choice randomized
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
January 01, 2014 - This guideline
stated that metronidazole
remains the choice for mild-
moderate disease but may
not … This guideline
stated that metronidazole
remains the choice for mild-
moderate disease but may
not … This guideline
stated that metronidazole
remains the choice for mild-
moderate disease but may
not … This guideline
stated that metronidazole
remains the choice for mild-
moderate disease but may
not
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
January 01, 2013 - ............................................................................................... 6
Choice … Choice of Priors
Lu and Ades assume a noninformative prior on each parameter, in order to let the data … informative Wishart priors in a sensitivity analysis.
8
Decisionmaking
Regarding Bayesian model choice … our data are sparse, heterogeneous variance assumption, a
feature of CBRE1 and ABRE1, is not a good choice