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161. Scientific Rationale | Agency for Healthcare Research and Quality
     www.ahrq.gov/hai/universal-icu-decolonization/universal-icu-rationale.html
     September 01, 2013 - intervention studies. 28-30 Importantly, one study suggests that the combination of mupirocin and CHG … eradicating MRSA than mupirocin alone. 31 Safety of Mupirocin and Chlorhexidine Both mupirocin and CHG … As an over-the-counter skin cleanser used in health care for over 50 years, CHG has an even more extensive … groups have confirmed the absence of systemic absorption following topical use or oral rinsing with CHG … The REDUCE MRSA Trial found negligible rate of skin reactions (<1 percent) from CHG use; two other large

162. Scientific Rationale | Agency for Healthcare Research and Quality
     www.ahrq.gov/es/hai/universal-icu-decolonization/universal-icu-rationale.html
     September 01, 2013 - intervention studies. 28-30 Importantly, one study suggests that the combination of mupirocin and CHG … eradicating MRSA than mupirocin alone. 31 Safety of Mupirocin and Chlorhexidine Both mupirocin and CHG … As an over-the-counter skin cleanser used in health care for over 50 years, CHG has an even more extensive … groups have confirmed the absence of systemic absorption following topical use or oral rinsing with CHG … The REDUCE MRSA Trial found negligible rate of skin reactions (<1 percent) from CHG use; two other large

163. 034-Ss-Action-Chart-Decisionmaking-Readiness (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/034-ss-action-chart-decisionmaking-readiness.docx
     April 01, 2025 - -acquired S.aureus infection by Mupirocin-CHG (p=0.008) N Engl J Med 2010; 362:9-17 Assess the Current … CHG bathing and nasal decolonization have been shown effective in reducing risk of S. aureus SSI and … Several studies, including randomized trials, included the use of CHG for 5 days leading up to surgery … We have also included alternative protocols for basin bathing using a 2% CHG solution diluted from 4% … CHG liquid, as well as 10% povidone-iodine (iodophor) swabs.

164. Four Key Strategies To Prevent MRSA & SSI (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/120-key-strategies-target-mrsa-ssi.pdf
     April 01, 2025 - • Preoperative bathing and antisepsis with chlorhexidine gluconate (CHG) reduces microbial burden … • CHG skin antisepsis should preferably be performed morning and evening for 5 days prior to and

165. Tools & Resources for Decolonization | Agency for Healthcare Research and Quality
     www.ahrq.gov/hai/tools/mrsa-prevention/toolkit/tools-resources-decolonization.html
     October 01, 2024 - patients in a specific hospital unit are treated with nasal decolonization for 5 days and decolonized with CHG … infection in a specific hospital unit are treated with nasal decolonization for 5 days and decolonized with CHG … Protocols This section provides sample unit and nursing protocols on bathing with chlorhexidine gluconate (CHG

166. 003-Clabsi-Prevention-Webinar-Fg (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/003-clabsi-prevention-webinar-fg.docx
     October 01, 2024 - The CHG must be allowed to dry completely before the skin is punctured. … A CHG-based antiseptic should be used to cleanse the site with each dressing change. … Slide 26 Daily CHG Treatment or Bathing SAY: Published evidence shows that routine CHG treatment … Chlorhexidine treatment is the process of using CHG-impregnated wipes or a CHG soap and water solution … This slide displays a diagram on how the CHG should be applied.

167. 053-Dec-Guide-Readiness (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/053-dec-guide-readiness.docx
     October 01, 2024 - implementation of decolonization, please refer to the presentation “Implementation of Chlorhexidine Gluconate (CHG … · Bed bathing with 2-percent CHG liquid solution, diluted from 4-percent CHG liquid in a basin · Patient … self-showering with 4-percent CHG liquid · Nasal decolonization with 2-percent mupirocin ointment · … It is worth noting that different methods of application may affect the concentrations of CHG applied … cloth baths to intranasal 2-percent mupirocin ointment plus 2-percent no-rinse CHG cloth baths, and

168. 133-Translating-Research-Into-Practice-Fg (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/133-translating-research-into-practice-fg.docx
     April 01, 2025 - through the lens of nasal decolonization and preoperative skin antisepsis with chlorhexidine gluconate (CHG … The best evidence for skin decolonization supports skin decolonization with CHG bathing for 5 days leading … As an alternative, CHG bathing the night before and morning of surgery also provides some benefit in … Slide 6 Common Barriers SAY: The majority of surgical providers are aware of the evidence to support CHG … If a patient arrives for surgery and they haven’t completed CHG bathing, is the product easily accessible

169. 159-Which-Type-Decolonization-Work-Best (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/159-which-type-decolonization-work-best.docx
     October 01, 2024 - unit are treated with nasal decolonization for 5 days and decolonized with chlorhexidine gluconate (CHG … infection in a specific hospital unit are treated with nasal decolonization for 5 days and decolonized with CHG

170. PowerPoint Presentation
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/104-what-are-4-es.pptx
     April 01, 2025 - Investigation revealed decolonization with preoperative CHG bathing has decreased in the last quarter … Patients are not given CHG products or mupirocin at their clinic visit. … Par levels of CHG wipes in pre-op area are low. … Bathing Cloths 4% Rinse-Off Liquid CHG for Shower | 21 Case Example AHRQ Safety Program for MRSA … 23 Monthly Decolonization Compliance (Percent) CHG Jan Feb Mar Apr 100 90 50 100 Nasal Jan Feb Mar

171. 130-Ss-Swiss-Cheese-Fg (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/130-ss-swiss-cheese-fg.docx
     April 01, 2025 - He was given instructions on chlorhexidine (CHG) bathing and mupirocin nasal decolonization prior to … 9 System Factors—1 SAY: Looking at this through a systems lens, the patient stated he completed CHG … These sessions could include a review of the decolonization process that includes both mupirocin and CHG … Although a pre-op checklist was completed in the holding area the checklist included CHG bathing but … the pre-op checklist could be revised to include specific questions about nasal decolonization and CHG

172. 121-Importance-Mrsa-Prevention-One-Pager (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/121-importance-mrsa-prevention-one-pager.docx
     April 01, 2025 - Strategies Nasal Decolonization · Nasal mupirocin (5 days pre-op) or iodine-based products8,9 Preoperative CHG … Skin Antisepsis8,9 · Decreases microbial burden on skin · CHG bathing 5 days pre-op (best evidence) … · CHG bathing night before and morning of surgery Antimicrobial Prophylaxis10 · The right drug, dose,

173. Importance of MRSA and SSI Prevention
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/018-ss-importance-ssi-mrsa-prevention.pptx
     April 01, 2025 - MRSA and SSI Prevention Phases: Importance of SSI and MRSA Prevention Office/Home Decolonization CHG … Bathing Pre-op Decolonization CHG Bathing Hand Hygiene  Hair Removal  Antimicrobial Prophylaxis Contact … Cleaning Immediate Post-op Optimize Tissue Oxygenation  Contact Precautions (if appropriate) Ongoing CHG … PMID: 26034956. 21 Preoperative CHG Skin Antisepsis Preoperative CHG bathing/skin antisepsis reduces … CHG Chemical Structure PubChem Identifier: CID 29089 URL: https://pubchem.ncbi.nlm.nih.gov/compound

174. 063-Ssi-Investigation-Tool-Cusp (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/063-ssi-investigation-tool-cusp.docx
     April 01, 2025 - _____ Did patient do CHG bathing 5 days prior to procedure? … ______ Did patient do CHG bathing the night before and morning of surgery? … Betadine  CHG/alcohol  Iodine/alcohol  Other  If Other, name: ____________ Oxygenation Was

175. 163-Central-Line-Rounds-Form (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/163-central-line-rounds-form.docx
     October 01, 2024 - Days in place: 3) Was the patient bathed with Chlorhexidine Gluconate (CHG)? … Yes No 4) Was the linen changed at the time of the CHG Bath?

176. 023-Ss-Cusp-Learning-From-Defects-Fg (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/023-ss-cusp-learning-from-defects-fg.docx
     April 01, 2025 - For instance, failure to perform the intended chlorhexidine gluconate (CHG) bathing and nasal decolonization … The team also found that the patient was not given adequate instructions on how to use CHG for bathing … Finally, the CUSP team discovered that the clinic/surgeon’s office did not have a supply of CHG bathing … The team considered providing CHG bathing products to patients. … Choosing between available products such as CHG wipes or CHG liquid, the metric would first require interviews

177. 060-Nursing-Protocol-Nasal-Iodophor (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/060-nursing-protocol-nasal-iodophor.docx
     October 01, 2024 - A recent study showed a mupirocin & CHG decolonization strategy to be more effective at reducing Staphylococcus … aureus isolates in the ICU compared to iodophor & CHG.1 However, iodophor has the advantage of bypassing

178. 140-Ssi-Investigation-Tool-Cusp-Completed (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/140-ssi-investigation-tool-cusp-completed.docx
     April 01, 2025 - 1    Did patient do CHG bathing 5 days prior to procedure? … ______ Did patient do CHG bathing the night before and morning of surgery? … Betadine  CHG/alcohol Iodine/alcohol  Other  If Other, name: ____________ Oxygenation: Was

179. Monthly Team Checkup Tool for MRSA Prevention (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/118-monthly-team-checkup-tool.pdf
     October 01, 2024 - month, what percentage of all patients received daily decolonization with chlorhexidine gluconate (CHG … patients with central lines or lumbar drains received daily decolonization with chlorhexidine gluconate (CHG … month, what percentage of all patients received daily decolonization with chlorhexidine gluconate (CHG … patients with central lines or lumbar drains received daily decolonization with chlorhexidine gluconate (CHG

180. 110-Ss-Lfd-Sample (doc file)
     www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/110-ss-lfd-sample.docx
     April 01, 2025 - Negatively Contributed Positively Contributed N/A Patient Did patient receive chlorhexidine (CHG … Protocol for review of CHG bathing and mupirocin decolonization with patient available in clinic. … checklist was completed, there was nowhere on the document that asked if the patient had completed CHG … However, written patient education materials for CHG bathing and nasal decolonization, reference material … the decolonization process that incorporates mupirocin for patients positive for MRSA, in addition to CHG