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  1. www.uspreventiveservicestaskforce.org/uspstf/recommendation/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
    January 10, 2017 - 2011 data, the estimated average annual prevalence of anencephaly and spina bifida combined was 6.5 cases … However, most cases occur in the absence of any personal or family history. … per 10,000 live births before the implementation of food fortification (1995 to 1996) to 7.0 cases per … The trial reported no cases of neural tube defects in the experimental group and 6 cases in the control … to folate deficiency have now been prevented, and subsequent cases result from a different etiology.
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening-1996
    January 01, 1996 - An estimated 172,000 new cases will be diagnosed in 1995, with an estimated 153,000 deaths. 1 Lung … Tobacco is associated with 87% of all cases of cancer of the lung, trachea, and bronchus. 2   Return … alone and 67 (42%) would have been detected by cytologic examination alone. 7 The majority of incident cases … -47%. 1 Under optimal conditions, survival can be higher. 10 , 12 , 13 Early detection of Stage I cases … A case-control study in Japan compared the screening histories of 273 fatal cases of lung cancer to 1,269
  3. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary27/breast-cancer-medications-for-risk-reduction-2013
    April 15, 2013 - trials indicated that tamoxifen and raloxifene reduced incidence of invasive breast cancer by 7 to 9 cases … fractures, but tamoxifen increased the incidence of thromboembolic events more than raloxifene by 4 cases … in 1000 women) 11 , 24 , 28 , 29  and raloxifene (RR, 1.60 [CI, 1.15 to 2.23]; 2 trials; 7 cases in … Tamoxifen caused more cases of endometrial cancer (RR, 2.13 [CI, 1.36 to 3.32]; 3 trials; 4 cases in … In STAR, raloxifene caused fewer cases of endometrial cancer (RR, 0.55 [CI, 0.36 to 0.83]; 5 cases in
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2003
    January 07, 2003 - women who have never been screened or who have not been screened within the past 5 years; additional cases … A majority of cases of invasive cervical cancer occur in women who are not adequately screened. 5 , 6 … Rates in the United States have decreased from 14.2 new cases per 100,000 women in 1973 to 7.8 cases … Natural history studies confirm that, in the vast majority of cases, the course of infection and cervical … cervical lesion identified; moreover, 2 high-grade lesions will have been missed by cytology for every 3 cases
  5. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/syphilis-pregnancy-draft-rec-bulletin.pdf
    December 23, 2024 - “Cases of congenital syphilis are 10 times higher now than they were a decade ago,” says Task Force member … “Almost 90% of cases of congenital syphilis could have been prevented with timely testing and treatment
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/7ZSKduUYHWKe7q_tTY9xbF
    April 01, 2013 - trials indicated that tamoxifen and raloxifene reduced incidence of invasive breast can- cer by 7 to 9 cases … and Ralox- ifene) showed that tamoxifen reduced breast cancer incidence more than raloxifene by 5 cases … fractures, but tamoxifen increased the incidence of throm- boembolic events more than raloxifene by 4 cases … Tamoxifen caused more cases of endometrial cancer (RR, 2.13 [CI, 1.36 to 3.32]; 3 trials; 4 cases in … In STAR, raloxifene caused fewer cases of endo- metrial cancer (RR, 0.55 [CI, 0.36 to 0.83]; 5 cases
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2012
    March 15, 2012 - Grade: D Risk Assessment Human papillomavirus (HPV) infection is associated with nearly all cases … An estimated 12,200 new cases of cervical cancer and 4210 deaths occurred in the United States in 2010 … Most cases of cervical cancer occur in women who have not been appropriately screened 2 , 3 . … group (16 vs. 20 cases;  P  = 0.67) 30 . … (7.44 vs. 8.50 cases, respectively) and cancer deaths (1.35 vs. 1.55, respectively) 4 .
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
    September 15, 2005 - In these cases, guidelines recommend that testing begin with a relative who has known breast or ovarian … of breast cancer would be prevented with mastectomy and 31 cases of ovarian cancer would be prevented … Sensitivity analyses indicate that preventing breast and ovarian cancer cases that occur by age 40 to … All estimates in the outcomes table are based on cases of cancer, not mortality. … Case-Control Studies Criteria Accurate ascertainment of cases.
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qd4Zm2Uk2LDuBPa9yyFBRM
    January 01, 2014 - An estimated 41 380 new cases of and 7890 deaths from cancer of the oral cavity and pharynx will occur … A total of 20% to 30% of cases of oral cancer worldwide are attributable to cigarette smoking (1). … In the United States, up to 75% of cases of oral cancer may be attributable to tobacco and alcohol use … Potential Preventable Burden Up to 75% of cases of oral cancer may be attributed to tobacco and alcohol … Nearly three fourths of all cases occur in men, making it the eighth most common cancer in men (it is
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vCzPVrVJfgFWfpWRdEHMKQ
    July 01, 2012 - Most cases of prostate cancer have a good prognosis even without treat- ment, but some cases are aggressive … There is convincing evidence that PSA-based screening programs result in the detection of many cases … The number of cancer cases that could be detected in a screened population is large; a single study in … point (2007 rate, 24.0 cases per 100 000 men). … however, some cases will be missed.
  11. www.uspreventiveservicestaskforce.org/uspstf/recommendation/oral-cancer-screening-1996
    January 01, 1996 - responsible for 2% of all cancer deaths in the U.S., and it is projected to account for over 28,000 new cases … Cancer of the lip accounts for 11% of new cases of oral cancer but only 1% of deaths. … In contrast, cancer of the pharynx accounts for 31% of new cases of oral cancer but 50% of deaths. 1 … as leukoplakia or erythroplakia. 3 Depending on the degree of histologic abnormality, up to 18% of cases … preventing the occurrence of second primary oral cancers. 17 Leukoplakia relapsed in a majority of cases
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/r7JMWkKKv2krN6cxKQUUfP
    January 01, 2010 - women who have never been screened or who have not been screened within the past 5 years; additional cases … • A majority of cases of invasive cervical cancer occur in women who are not adequately screened.5,6 … Scientific Evidence Epidemiology and Clinical Consequences Approximately 13,000 new cases of cervical … Rates in the U.S. have decreased from 14.2 new cases per 100,000 women in 1973 to 7.8 cases per 100,000 … Natural history studies confirm that, in the vast majority of cases, the course of infection and cervical
  13. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - In placebo-controlled trials, tamoxifen (RR, 0.69 [95% CI, 0.59-0.84]; 7 fewer cases per 1000 women over … In the STAR head-to-head trial, raloxifene was associated with fewer cases of endometrial cancer (RR, … [95% CI, 4-12] a ), ER+ breast cancer (RR, 0.58 [95% CI, 0.42-0.81]; 8 fewer cases [95% CI, 4-13] a … [95% CI, 3-15] a ), ER+ breast cancer (RR, 0.33 [95% CI, 0.15-0.70]; 8 fewer cases [95% CI, 4-13] a … [95% CI, 8-24] a ) and ER+ breast cancer (RR, 0.37 [95% CI, 0.19-0.63]; 15 fewer cases [95% CI, 8-20
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening-december-2013
    December 31, 2013 - risk factor for lung cancer is smoking, which results in approximately 85% of all U.S. lung cancer cases … Detection Most lung cancer cases are NSCLC, and most screening programs focus on the detection and … A modeling study performed for the USPSTF estimated that 10% to 12% of screen-detected cancer cases are … However, only 15% of lung cancer cases are diagnosed at such a stage 2 . … Adenocarcinoma is the most common subtype, encompassing 36% of all lung cancer cases.
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening-2009
    December 15, 2009 - Contrast-enhanced MRI has been shown to detect more cases of cancer in very high-risk populations than … detects some cases of cancer not identified by digital mammography. … In these studies, MRI detected more cases of cancer than did mammography. … In 2008, an estimated 182,460 cases of invasive cancer and 67,770 cases of in situ breast cancer were … In 1983, 4900 cases of DCIS were diagnosed; by 2008, that number was expected to be 67,770 22 .
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
    May 18, 2021 - In determining whether this service is appropriate in individual cases, patients and clinicians should … diagnosed among persons aged 65 to 74 years. 2 It is estimated that 10.5% of new colorectal cancer cases … per 100,000 persons aged 40 to 49 years, 47.8 new cases per 100,000 persons aged 50 to 59 years, and … From 2013 to 2017, incidence rates for colorectal cancer were 43.6 cases per 100,000 Black adults, 39.0 … cases per 100,000 American Indian/Alaska Native adults, 37.8 cases per 100,000 White adults, 33.7 cases
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-in-pregnant-women-screening
    July 23, 2019 - Grade: A Risk Assessment In the United States, new cases of HBV among adults are largely transmitted … through injection drug use or sexual intercourse, but most prevalent cases of HBV infection are chronic … Data from a nationally representative sample showed a prevalence of maternal HBV infection of 85.8 cases … . 1 , 18-20 In the United States, new cases of HBV among adults are largely transmitted through injection … drug use or sexual intercourse, but most prevalent cases of HBV infection are chronic infections from
  18. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/cervical-cancer-screening-adults-adolescents
    December 10, 2024 - Most cases of cervical cancer occur among women who have not been adequately screened, diagnosed, or … The age-adjusted incidence of cervical cancer in 2021 was 7.6 cases per 100,000 women per year. … In 2024, there will be an estimated 13,820 new cases of cervical cancer and 4,360 deaths. 2 The mortality … and 2.1 cases per 100,000 persons, respectively). 2 However, data from the Surveillance, Epidemiology … of cervical cancer; although, six cases of high-grade vaginal lesions were detected, it is not known
  19. www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/lung-cancer-screening
    March 09, 2021 - Estimated lifetime number of LDCT screenings, false-positive results, biopsies, overdiagnosed cases, … per person screened vs 1.9 per person screened with the USPSTF strategy), overdiagnosed lung cancer cases … (defined as lung cancer cases detected by screening that would not have been diagnosed nor caused death … This shift leads to higher numbers of deaths averted and overdiagnosed lung cancer cases and to lower … % of all lung cancer cases % of screening- detected cases Radiation- related lung cancer deaths
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3UuREAobGvgLbE_FBAnrYQ
    January 13, 2025 - Nearly all cases of cervical cancer are caused by human papillomavirus (HPV), a sexually transmitted … • Nearly all cases of cervical cancer are caused by HPV, and most are in women who have not been

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