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  1. effectivehealthcare.ahrq.gov/sites/default/files/epc-disclosure-policy-form.pdf
    March 01, 2023 - In many cases, the EPC Director may designate one person as the Lead Investigator and delegate some … Depending on the nature of the financial COI, in some cases these conflicts may be managed by divestment … pool of experts, the EPC and AHRQ may elect to balance COI across all involved individuals (as in the cases … Depending on the nature of the financial COI, in some cases these conflicts may be managed by divestment … pool of experts, the EPC and AHRQ may elect to balance COI across all involved individuals (as in the cases
  2. DRN: Report 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-safety_research.pdf
    July 01, 2009 - In some cases, this information may directly inform policy and decision-making. … Figures 2 through 5 are a depiction of the current use cases for a distributed network. … Use cases for stakeholder discussions: complex querying Ad hoc ETL from Network datamart to Project … Use cases for stakeholder discussions: menu-driven querying Menu-driven Querying Use Cases 1. … AHRQ input helped to inform the use cases and the system architecture iterations.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
    November 01, 2010 - We felt that this criterion was applicable in cases in which more than one “good” study was available … Again, these tests appear to have been considered acceptable in some cases (e.g., Eikeseth et al., … More systematic clarification of these decisions might be helpful in some cases.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
    February 01, 2012 - Thus, the disease natural history in those cases assumed the role of comparator. … moderate-strength evidence suggests that extended periods of drug-free clinical remission can be achieved in some cases … This does not imply that the intervention will succeed in all cases, but that the effects observed
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
    December 08, 2014 - 402,236 people in the United States were living with lung cancer.3 In 2014, approximately 224,210 new cases … Although most cases are diagnosed after patients become symptomatic with cough, shortness of breath, … In these cases, treatment primarily consists of palliative chemotherapy. … Intravenous injection of a radio-opaque contrast agent may be performed in some cases. … : mostly cases where PET/CT detects extensive disease that was not detected by other modalities.
  6. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - In the United States, the incidence today is nearly 3 times that of 30 years ago, rising from 3.6 cases … per 1 million people in 1973 to 25.6 cases per 1 million people in 2006. … However, universal screening with endoscopy is not recommended because most cases of Barrett’s esophagus … per 1 million people in 1973 to 25.6 cases per 1 million people in 2006.2 Similar large increases … Disability due to irritable bowel syndrome is not the norm, but it does occur in some cases.
  7. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
    December 11, 2015 - Identify cases for use in analysis. … A study with three arms provides 2 cases for analysis. 3. … For example, cases assigned a condition value of 1 for financial components have at least one financial … We assign a value of 1, indicating evidence of improvement) to cases that demonstrated a statistically … We assign a value of 0, indicating no evidence of improvement, to cases that demonstrated a statistically
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
    April 01, 2015 - is uterine atony (impaired uterine contraction after birth), which occurs in about 80 percent of cases … prospective/retrospective cohort studies, population-based case series or registry studies with ≥50 cases … women who received interventions such as massive transfusion or hysterectomy likely had more severe cases … short-term study with high study limitations, bleeding was controlled by carboprost in 81% of 237 cases … In some cases, it can be difficult to assess if harms are due to PPH or management interventions and
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
    November 01, 2012 - In such cases, we refer to an established checklist for the minimum amount of information needed to … In some cases, search dates are dependent upon when the technology or intervention was first developed … These cases require organization of the results by the most important parameters of the particular … In such 15 cases, the Cover Sheet should include details on what the ongoing activity is, how … In such cases, communication with the partnering organization is essential to ensure that the timing
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
    October 01, 2016 - In some cases, the distinction between structural and parametric uncertainty is a matter of definition … In some cases, a short time horizon may be adequate to compare interventions (e.g., when modeling the … In all these cases, evidence from other study designs will have to be included in the model. … However, in many cases, studies free of bias are unavailable or represent a very small fraction of the … In such cases, modelers should adjust study results to account for bias and associated uncertainties
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
    July 17, 2020 - Surveillance Report: Masks for Prevention of COVID-19 in Community and Healthcare Settings Surveillance Report: July 17, 2020 Masks for Prevention of COVID-19 in Community and Healthcare Settings: Surveillance Report Background This surveillance report summarizes the search and update for the rapid review and l…
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
    May 14, 2025 - " - Consider adding a 4th potential harm (when considering MCST versus SOC in some cases): the … a cross-sectional snapshot of test accuracy at or shortly after the time of cancer diagnosis for cases … of context: the cancer type, the type of study (diagnostic or pre-diagnostic), the stage of the cases … This far outweighs the positive cancer signal cases and in the real world will be a huge clinical burden … at late stages13, and more than 600,000 people die of cancer every year in the US • New cancer cases
  13. Title (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
    September 13, 2012 - www.effectivehealthcare.ahrq.gov/ Source: www.effectivehealthcare.ahrq.gov Published Online: September 13, 2012 cases … diagnosis of schizophrenia, schizoaffective disorder, bipolar disorder, or major depression or, in cases … Likewise, in cases where there is a disagreement between the two abstract reviewers, the full article
  14. effectivehealthcare.ahrq.gov/sites/default/files/bar-cohen-ii_eccs2012.pdf
    January 01, 2012 - the women featured in these stories were diagnosed after age 60, even though half of breast cancer cases
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-533_05-24-2013.pdf
    January 01, 2013 - ii. follow-up testing; iii. invasive procedures (biopsies); iv. cases
  16. effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
    January 01, 2012 - The Sequenom assay detected all 39 cases of trisomy 21 (100% sensitivity; 95% confidence interval [ … The authors concluded, “The study correctly identified 89 of 89 cases of trisomy 21 (Down syndrome) … 18 was ≥99% in 47 cases, 98.8% in 1 case, 88.5% in 1 case, and 0.11% in 1 case.” 59 It was also … 18 was ≤0.01% in 295 cases, 0.04% in 1 case, and 0.23% in 1 case. … 18 was 98% (49/50 cases), and the specificity was 100% (297/297 cases).” 59 In May 2012, the company
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
    September 01, 2014 - Due to this delayed diagnosis, approximately 80 percent to 85 percent of cases are too Effective … As noted, most cases are diagnosed at an advanced stage, precluding surgical resection.1 When pancreatic … In most cases, the combined evidence indicated neither a difference nor equivalence between two imaging … For two cases, however, the evidence was sufficient to permit conclusions. … For three cases, however, the evidence was sufficient to permit conclusions.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
    January 01, 2011 - are not clearly reported Poor reporting B Sampling of controls from the sample population as cases … C Sampling of controls from different population as cases Major flaw D Sampling of controls … the same as for controls C % of nonresponse differed among cases and controls Minor flaw … D % of nonresponse reported for cases only Minor flaw E Other (please specify) Mask Exposure … and controls Minor flaw % of nonresponse reported for cases only Minor flaw Masking of
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
    August 10, 2010 - In some cases increases in prescriptions have been linked to specific physicians, suggesting that increases
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
    January 01, 2023 - Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings: Systematic Review Update Evidence-based Practice Center Systematic Review Protocol Project Title: Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings: Systematic Review Update I. Background and Object…

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