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41. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
    October 01, 2021 - • No studies reported long-term cardiovascular or metabolic disease health outcomes. … Key Question 1: Prevention of Cardiovascular Conditions, Diabetes, and Obesity No included study … (n=168) or study excluded at the full-text level provided evidence on the prevention of cardiovascular … physical activity improved walking ability, function, balance, sleep, activities of daily living, cardiovascular … No studies reported long-term cardiovascular or metabolic disease health outcomes.

42. Dietary Supplements in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/dietary-supplements/research

43. Disposition of Comments_Systematic Review: The Relationship of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-disposition-comments_0.pdf
    March 03, 2025 - Disposition of Comments_Systematic Review: The Relationship of Digestible Carbohydrate Intake With Cardiovascular … Systematic Review Disposition of Comments Report Title: Association of Digestible Carbohydrate Intake With Cardiovascular … Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, … over 60% of these studies focus on outcomes relevant to this AHRQ review: weight/body composition, cardiovascular … Conducting a scientific review on the relationship between digestible carbohydrate intake and cardiovascular

44. ADHD Medications and Risk of Serious Coronary Heart Disease in Yough and Middle-Aged Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-heart-disease-children_research.pdf
    January 01, 2023 - disease rises due to the increasing prevalence of cardiovascular disease risk factors. … Prevalences in the year prior to baseline of most cardiovascular disease conditions and cardiovascular … We adjusted for a large number of established and potential cardiovascular risk factors. … ADHD drugs and cardiovascular risk. N Engl J Med 2006 Apr 6;354(14):1445-8. 6. … Cardiovascular effects of atomoxetine in children, adolescents, and adults.

45. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
    April 22, 2013 - Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious … Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness. … Peer Reviewer 4 Introduction The introduction is clear and describes the risk for cardiovascular disease … We added comments on the impact of low socioeconomic status on cardiovascular risk factors. … Cardiovascular disease and metabolic risk factors in male patients with schizophrenia, schizoaffective

46. Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic Review. Evidence Summary. (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - Abbreviations: BDI=Beck Depression Inventory; CI=confidence interval; MACE=major adverse cardiovascular … not generalized to all antidepressants (e.g., tricyclic antidepressants), which may have adverse cardiovascular … The included studies did not show a clear beneficial effect of depression treatment on cardiovascular … Given the inconsistency and imprecision of findings, and the small number of studies evaluating cardiovascular … outcomes, the effects of depression interventions on such cardiovascular outcomes is uncertain.

47. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - Most studies evaluated all-cause or cardiovascular mortality or cardiovascular morbidity. … All-Cause Mortality, Cardiovascular Mortality, and Cardiovascular Morbidity Only one comparison had … cardiovascular disease mortality less than metformin. … Results of a reevaluation of cardiovascular outcomes in the RECORD trial. … Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes.

48. What do we know about how evidence of harm and benefit is communicated in other countries? (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
    January 01, 2005 - Kingdom National Institute for Health and Clinical Excellence (NICE)—Statins for the prevention of cardiovascular … events (2006) Statins for the prevention of cardiovascular events. … Understanding NICE guidance—information for people who have or are at increased risk of cardiovascular … effective-ness, but not strength of evidence United Kingdom Statins for the Prevention of Cardiovascular … www.nhmrc.gov.au/publications/synopses/cp94syn.htm NICE: Statins for the Prevention of Cardiovascular

49. Effects of Dietary Sodium and Potassium Intake on Chronic Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
    April 18, 2017 - ; cardiovascular disease morbidity, including coronary heart disease (CHD), acute coronary syndrome … Global sodium consumption and death from cardiovascular causes. … Reduced dietary salt for the prevention of cardiovascular disease. … Reduced dietary salt for the prevention of cardiovascular disease. … Salt intake, stroke, and cardiovascular disease: meta- analysis of prospective studies.

50. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - Director, Echocardiography Laboratory VA Palo Alto Medical Center Professor of Medicine (Cardiovascular … Director, Cardiovascular Imaging Center Professor of Radiology and Medicine University of Virginia … Imaging and Intervention Committee, Council on Cardiovascular Radiology and Intervention, American … Society of Cardiovascular Computed Tomography The Society of Cardiovascular Computed Tomography is … events (nonfatal and fatal myocardial infarction, cardiovascular death).

51. High-Cholestorol-Medicines-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
    February 01, 2014 - Sex/gender differences in cardiovascular disease prevention: what a difference a decade makes. … without preexisting cardiovascular disease. … HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. … Dietary advice for reducing cardiovascular risk. Cochrane Database Syst Rev. 2013;(3):CD002137. … Reduced or modified dietary fat for preventing cardiovascular disease.

52. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
    January 31, 2013 - Reducing Cardiovascular Morbidity and Mortality in All Patients With PAD The goal of medical therapy … is to reduce the risk of future cardiovascular morbidity and mortality in patients with high ischemic … events (e.g., all-cause mortality, myocardial infarction, stroke, cardiovascular death), functional … Risk factors for atherosclerotic cardiovascular outcomes in different arterial territories. … FDA approved Diamondback 360 atherectomy Orbital atherectomy Cardiovascular Systems Inc.

53. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
    September 29, 2011 - Background and Objectives for the Systematic Review Overview Cardiovascular disease remains … the leading cause of death among women in United States. 1 More than 500,000 women die of cardiovascular … First, cardiovascular disease affects women later in life. … Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update. … Representation of women in randomized clinical trials of cardiovascular disease prevention.

54. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
    May 01, 2012 - Antipsychotic Use and Risk of Sudden Cardiac Death by Cardiovascular Risk Score .................. … Because data suggest that NSAID cardiovascular effects vary according the specific drug,19,20,21 it … The study defines surrogate measures of cardiovascular risk factors from medical care encounters. … Antipsychotic use and risk of sudden cardiac death by cardiovascular risk score Cardiovascular Disease … Adjustment for multiple cardiovascular risk factors using a summary risk score.

55. Protocol for Quantitative Assessment of Benefit and Harm analysis of Aspirin for primary prevention (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
    February 01, 2014 - Methods Research Report Evaluation of the Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular … Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease … Incidence and Prevalence: 2006 Chart Book on Cardiovascular and Lung Diseases. … Aspirin for the prevention of cardiovascular disease: U.S. … Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease

56. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - The outcomes analyzed in this comparison will include relative benefits (blood pressure control, cardiovascular … risk reduction, cardiovascular events, quality of life, and other outcomes) and safety (adverse events … risk reduction, cardiovascular events, quality of life, and other outcomes? … disease-specific, and cerebrovascular disease-specific) o Morbidity (especially major cardiovascular … disease-specific, and cerebrovascular disease-specific) or morbidity (especially major cardiovascular

57. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - adult patients1 with essential hypertension, how do ACEIs and ARBs2 differ in blood pressure control, cardiovascular … risk reduction, cardiovascular events, quality of life, and other outcomes? … Health outcomes—Mortality (all-cause mortality, cardiovascular disease-specific mortality, and cerebrovascular … Mortality and major Moderate Due to insufficient numbers of deaths or major cardiovascular events cardiovascular … In particular, there is a lack of information about death or major cardiovascular events, and data on

58. Untitled (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
    July 06, 2015 - Relationship between healthy diet and risk of cardiovascular disease among patients on drug therapies … Fibroblast growth factor-23, cardiovascular prognosis, and benefit of angiotensin-converting enzyme … The TRANSCEND (Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular … ; CVD=cardiovascular disease; MI=myocardial infarction; PL=placebo; WDAE=withdrawals due to adverse … ARB therapy was associated with reductions in the composite endpoint of cardiovascular mortality,

59. Kidney-Disease-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
    October 01, 2012 - disease or the combination of diabetes and other cardiovascular risk factors. … Because even populations with a high CKD prevalence (e.g., diabetes, hypertension, cardiovascular … disease or diabetes combined with other cardiovascular risk factors (e.g., hypertension) and are … Renal outcomes in hypertensive Black patients at high cardiovascular risk. … disease or the combination of diabetes and other cardiovascular risk factors.

60. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure_research-protocol.pdf
    April 11, 2011 - disease and mortality, accounting for an estimated 14 percent of cardiovascular deaths worldwide and … Outcomes:  Clinical outcomes (KQs 1a, 2, 3, and 4) o Cardiovascular events (myocardial infarction … o Cardiovascular disease mortality. o All-cause mortality. … We will extract basic demographic data such as age, sex, and race; diabetes, cardiovascular disease, … Trends and cardiovascular mortality effects of state-level blood pressure and uncontrolled hypertension