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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
    October 01, 2011 - company dedicated to the research and development of new medicines in therapeutic areas including cardiovascular … , starting line 41) states “many trials, but almost exclusively in patients receiving aspirin for cardiovascular … and bone fractures (8) - Increased incidence of infectious processes (9) - Increased incidence of cardiovascular … diseases, effect that may potentiate the cardiovascular ADEs of NSAIDs. … Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
    May 26, 2015 - Health and safety outcomes (e.g., cardiovascular events or incidence of work- related injuries) Source … o KQ 2a: Health and safety outcomes: Mortality; incidence of injuries, cardiovascular disease or cancer
  3. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Additionally, patients with chronic hyperuricemia have an increased risk of cardiovascular disease, … However, better gout management could reduce hospitalizations and renal or cardiovascular complications
  4. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - example of a prediction model is by Dorresteijn et al., who predicted the effect of rosuvastatin on cardiovascular … scores), as well as a prediction model developed using the trial data to calculate baseline risk of cardiovascular
  5. effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
    January 01, 2011 - Ray and colleagues39 reported effect modification by cardiovascular disease risk, derived and summarized … Adjustment for multiple cardiovascular risk factors using a summary risk score.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes … Cardiovascular safety of non-steroidal anti- inflammatory drugs: network meta-analysis. … One considered frequently is major adverse cardiovascular events. … Statin Monotherapy: An Update Johns Hopkins University, 2014 Adults with moderate or high cardiovascular
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
    January 01, 2006 - Aspirin and antiplatelet/anticoagulant agents Rofecoxib=35.3% Celecoxib=21.9% p<0.0001 (a) Cardiovascular … (n=19,087); rofecoxib 7/99- 9/99 (n=15,268) 270 NR NR Meloxicam NR Thromboembolic events: (A) cardiovascular … (AMI) between January 1, 1992 and October 31, 1997; ≤ 75 years of age; free of metabolic or cardiovascular … aged 50 years or younger ≥ 60 prior to event NR NR Other NSAIDs (excluding naproxen) NR Cardiovascular … solution qid 4 weeks 1-week washout for patients on NSAIDs Aspirin up to 325 mg/day for cardiovascular
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
    April 01, 2022 - mechanism vs. opioid agonist and mortality, falls/fracture, hospitalization for adverse event, or cardiovascular … studies 1 retrospective cohort study (n=77,697) found tramadol associated with decreased risk of cardiovascular … hospitalizations compared with opioid agonists.6 Tramadol was associated with slightly decreased risk of cardiovascular … harms, falls, fractures, motor vehicle accidents, B-2 endocrinological harms, infections, cardiovascular … (gastrointestinal, somnolence, pruritus, dizziness, headache, fracture, motor vehicle accidents, cardiovascular
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes … Meta- analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized … Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death
  10. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes … Meta- analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized … Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death
  11. effectivehealthcare.ahrq.gov/products/peripheral-artery-disease-treatment/research
  12. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
    January 01, 2015 - Food and Drug Administration (FDA) has requested additional cardiovascular data from a dedicated cardiovascular … A global cardiovascular outcomes trial is under way comparing insulin degludec to insulin glargine … in patients with T2DM at high risk of cardiovascular events. … Prespecified interim analysis of major adverse cardiovascular events is anticipated by mid-2015. … This increases the risk of secondary complications, including cardiovascular disease, retinopathy,
  13. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
    January 01, 2009 - Study Group found reduced smoking prevalence in people screened compared to those unscreened in a cardiovascular … Randomised controlled trial evaluating cardiovascular screening and intervention in general practice
  14. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
    January 01, 2009 - Study Group found reduced smoking prevalence in people screened compared to those unscreened in a cardiovascular … Randomised controlled trial evaluating cardiovascular screening and intervention in general practice
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
    January 01, 2007 - and is the leading cause of death in adults less than 65 years old.7 SCD accounts for 50-63% of all cardiovascular
  16. effectivehealthcare.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
    January 01, 2005 - and is the leading cause of death in adults less than 65 years old.7 SCD accounts for 50-63% of all cardiovascular
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
    November 01, 2016 - immediate-release) ��Misuse, abuse, addiction, overdose, and death Nonsteroidal anti-inflammatory drugs ��Cardiovascular
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
    June 01, 2016 - Longer term effects on cardiovascular and metabolic parameters known to be affected by beta-blocker
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
    January 01, 2024 - The value of anticoagulation management combining telemedicine and self-testing in cardiovascularCardiovascular Quality And Outcomes, 2023, 16(2):e009256. Not an intervention of interest. 7. … European Journal Of Cardiovascular Nursing, 2019, 18(5):358-365. … Journal Of Cardiovascular Electrophysiology, 2019, 30(5):631-638. … the effects of educational programs on patients prescribed warfarin for the aforementioned cardiovascular
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
    February 01, 2019 - Specific adverse events for each drug class, such as gastrointestinal events, cardiovascular events, … • Key specific adverse events, according to drug class, such as gastrointestinal and cardiovascular

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