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181. Screening for Ovarian Cancer - Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
     May 01, 2004 - Two large cohort studies using transvaginal ultrasound screening reported that 59% to 65% of ovarian cancers … were diagnosed in Stage I.11,12 However, there is no evidence that detecting earlier-stage tumors through … assumption that earlier treatment leads to a 40% mortality reduction) would yield a maximum of 4 additional cancers … American Cancer Society. Cancer Facts & Figures 2003. … Invasive epithelial ovarian cancers in white women. Collaborative Ovarian Cancer Group.

182. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
     February 01, 2008 - e.g., Gleason score, tumor volume, screen vs. clinically detected tumors) affect the outcomes of interventions … How do tumor characteristics, e.g., Gleason score, tumor volume, screen vs. clinically detected tumors … Men with low-grade prostate cancers had a minimal risk of dying from prostate cancer (7 percent with … Low • The risk of overall or prostate cancer death over 10 years for PSA-detected prostate cancers according … High • Screening with PSA testing detects more prostate cancer and cancers of smaller volume, earlier

183. Statistical Brief #125: Cancer Hospitalizations for Adults, 2009 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb125.pdf
     February 01, 2012 - among men, breast cancers among women, and colorectal cancers among both men and women. … , secondary malignancies (i.e., metastatic cancer), and lung cancer. … cancer, secondary malignancies (i.e., metastatic cancers), and lung cancer (figure 1). … Cancer of colon* Cancer of bronchus, lung Secondary malignancies Cancer of prostate Figure 1.  … Cancer of uterus Cancer of colon* Cancer of bronchus, lung Cancer of breast* Secondary malignancies

184. Collaborative Modeling of U.S. Breast Cancer Screening Strategies (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/nmcMhEwWT9BncBBBQQN6Uf
     December 01, 2015 - of breast cancer is modeled as a continuously growing tumor. … Each tumor has a size (the fatal diameter, which differs between tumors) at which diagnosis and treatment … Variation between tumors is modeled by probability distributions of tumor growth, threshold diameter … The MISCAN-Fadia continuous tumor growth model for breast cancer. … Number of cancers diagnosed is higher in B50–74 vs.

185. Resources for Women’s Health | Agency for Healthcare Research and Quality
     www.ahrq.gov/prevention/resources/womens-health.html
     July 01, 2018 - , Bone, and Joint Conditions Pregnancy and Childbirth Smoking Cessation Wellness Cancer Cancer is a term … Cancers are described based on the origin of the tumor, including— Carcinoma—cancers derived from epithelial … Sarcoma—cancers arising from connective tissue. … Germ cell tumor—cancers derived from pluripotent cells, most often presenting in the ovary. … Blastoma—cancers derived from immature precursor cells or embryonic tissue.

186. Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
     January 31, 2023 - Partial Breast Irradiation for Breast Cancer. Comparative Effectiveness Review No. 259. … • One reviewer suggested changing the terminology “ipsilateral breast tumor recurrence (IBTR)” to … size, tumor grade) in Appendix Table J subgroup analyses. … The results and discussion sections describe findings of the analysis of tumor size. … state that clinicians can consider treating with 26Gy in 5 fractions using mini-tangents for larger tumors

187. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
     April 01, 2013 - The prostate cancer antigen-3 gene (PCA3) has recently been found to be overexpressed in prostate cancers … research question would be to determine if the trade-off between reduction in biopsies and missed cancers … and what is learned through the studies in Research Question 2.1 about likely behavior of cancers … Can intermediate outcomes, such as cancer classifications of aggressive or indolent tumors be properly … PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates

188. The Fluidity of Diagnostic "Wet Reads" | PSNet
     psnet.ahrq.gov/web-mm/fluidity-diagnostic-wet-reads
     April 24, 2018 - Although subsolid nodules are often malignant or premalignant, they usually give rise to malignancies … that behave more indolently than solid malignancies. … lung cancer. … September 26, 2012 Errors in the MRI evaluation of musculoskeletal tumors and tumorlike … May 1, 2011 Missed breast cancers at US-guided core needle biopsy: how to reduce

189. Archived: Letter to the Editor and Response from the Evidence-Based Practice Center: Human Papillomavirus Testing to Screen for Cervical Cancer: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/letter-to-the-editor-and-response-from-the-evidence-based-practice-center--human-papillomavirus-testing-to-screen-for-cervical-cancer/cervical-cancer-screening-2012
     February 15, 2012 - In this trial 5 , there were proportionally more cancers with cytology because the cotesting:cytology … Human papilllomavirus DNA testing for the detection of cervical intraepithelial neoplasia grade 3 and … intraepithelial neoplasia: a randomised controlled trial. … intraepithelial neoplasia: a randomised controlled trial. … Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer

190. 04-E029-1 Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
     December 01, 2011 - The cancer is usually localized, and most tumors have low histological grades and low Gleason scores. … low-risk tumors. … cancer patients with other primary tumors were consistently less likely to die of prostate cancer compared … Tumor grade Three studies reported information on prostate cancer mortality stratified by tumor grade … The two studies reporting on T1/T2 tumors both demonstrated a decrease of T1a/T1b tumors and T2a tumors

191. Archived: Cervical Cancer: Screening, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-1996
     January 01, 1996 - Although the Pap smear can sometimes detect endometrial, vaginal, and other cancers, 3 , 4 its use as … cytologic diagnoses, false-negative diagnoses were made in 7.5% of smears with moderate dysplasia or frank malignancy … and invalid assumptions that an interval longer than 1 year may permit aggressive, rapidly growing cancers … recommended that the first two to three smears be obtained 1 year apart as a means of detecting aggressive tumors … Controversies in the management of low-grade cervical intraepithelial neoplasia.

192. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/43578/psn-pdf
     October 01, 2014 - Some cancer experts see 'overdiagnosis,' question emphasis on early detection. … https://psnet.ahrq.gov/issue/some-cancer-experts-see-overdiagnosis-question-emphasis-early-detection … of tumors that may never cause harm, this newspaper article discusses the impact of unnecessary tests … Researchers are working to design better tests to distinguish between benign abnormalities and cancers … https://psnet.ahrq.gov/issue/some-cancer-experts-see-overdiagnosis-question-emphasis-early-detection

193. Partial Breast Irradiation for Breast Cancer: Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
     August 09, 2021 - First, screening mammography has resulted in increased detection of smaller tumors, and in countries … of PBI, such as larger tumor size (2-3 cm), high tumor grade, close margins, human epidermal growth … recurrence (i.e., tumor bed ipsilateral breast cancer recurrence, elsew here ipsilateral breast cancer … Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers … Non-Indexed Citations and Daily 1946 to June 29, 2021 Search Strategy: # Searches 1 exp Breast Neoplasms

194. Archived: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2003
     January 07, 2003 - The majority of cervical cancers in the United States occur in women who have never been screened or … of cytological screening after total hysterectomy for benign disease (e.g., no evidence of cervical neoplasia … or DES exposure due to increased risk for vaginal neoplasms, but data on the yield of such screening … American Cancer Society Guideline for the Early Detection of Cervical Neoplasia and Cancer. … Trends in cervical intra-epithelial neoplasia in Iceland through 1995: evaluation of targeted age groups

195. Collaborative Modeling of U.S. Breast Cancer Screening Strategies (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16255/collabmodelingbc/pdf
     December 01, 2015 - of breast cancer is modeled as a continuously growing tumor. … Each tumor has a size (the fatal diameter, which differs between tumors) at which diagnosis and treatment … Variation between tumors is modeled by probability distributions of tumor growth, threshold diameter … The MISCAN-Fadia continuous tumor growth model for breast cancer. … Number of cancers diagnosed is higher in B50–74 vs.

196. Breast Cancer | Digital Healthcare Research
     digital.ahrq.gov/medical-condition/breast-cancer
     January 01, 2025 - Breast Cancer Workflow analysis of breast cancer treatment decision-making … to support patient-centered cancer care. … Support Care Cancer. 2024 Jun 21;32(7):449. doi: 10.1007/s00520-024-08672-3. … commercial artificial intelligence algorithm on a diverse population for detection of false negative breast cancers … commercial artificial intelligence algorithm on a diverse population for detection of false negative breast cancers

197. How timely is diagnosis of lung cancer? Cohort study of individuals with lung cancer presenting in ambulatory care in the United States. | PSNet
     psnet.ahrq.gov/issue/how-timely-diagnosis-lung-cancer-cohort-study-individuals-lung-cancer-presenting-ambulatory
     September 14, 2022 - How timely is diagnosis of lung cancer? … Cancers (Basel). 2022;14(23):5756. doi:10.3390/cancers14235756. … Cancers (Basel) . 2022; 14 (23) :5756 . View more articles from the same authors. … How timely is diagnosis of lung cancer? … Cancers (Basel). 2022;14(23):5756. doi:10.3390/cancers14235756.

198. Evidence Summary: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/lung-cancer-screening
     March 09, 2021 - Lung-RADS category 4X: does it improve prediction of malignancy in subsolid nodules? … Extrapulmonary findings and malignancies in participants screened with chest CT in the National Lung … harms Estimates were not provided for lifetime risk of radiation-induced cancers or fatal cancers … across studies (range, 20%-80%) and by subgroups defined by clinical characteristics (eg, operability of tumor … in stage I lung cancers of 19% to 27%, decrease in stage IV lung cancers of 14% to 19% were associated

199. Safety and diagnostic accuracy of tumor biopsies in children with cancer. | PSNet
     psnet.ahrq.gov/issue/safety-and-diagnostic-accuracy-tumor-biopsies-children-cancer
     September 23, 2020 - Study Safety and diagnostic accuracy of tumor biopsies in children with cancer. … Safety and diagnostic accuracy of tumor biopsies in children with cancer. … Cancer. 2015;121(7):1098-107. doi:10.1002/cncr.29167. … Safety and diagnostic accuracy of tumor biopsies in children with cancer. … Cancer. 2015;121(7):1098-107. doi:10.1002/cncr.29167.

200. Gastric-Cancers-Supplementary-App-D (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
     January 01, 2023 - ROB 2 Study name Applicable outcome Randomization process Deviations from intended interventions Missing outcome data Measurement of the outcome Selection of the reported result Overall Comments ACTS-GC OS Low Low Low Low Low Low Low in all domains ACTS-GC Grade 3 to 5 AEs Low Low Low Low Low Low Low in all domains …