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www.uspreventiveservicestaskforce.org/home/getfilebytoken/n6eeEADXc8hR25c3XkgezA
Screening for Breast Cancer Background
Screening for Breast Cancer Final Recommendations … BACKGROUND
Summary
Mammography is an important tool in reducing the number of deaths due to breast cancer … screening include:
• Overdiagnosis and overtreatment, meaning that a woman would undergo treatment for a tumor … biopsies and
psychological harms (such as anxiety); and
• False-negative test results or missed cancers … Breast cancer caused by radiation, while infrequent, is another potential harm.
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psnet.ahrq.gov/issue/breast-cancer-screening-denmark-cohort-study-tumor-size-and-overdiagnosis
July 10, 2018 - study of tumor size and overdiagnosis. … Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis. … increased incidence of nonadvanced tumors and ductal carcinoma in situ; the rate of overdiagnosis was … Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis. … October 10, 2012
Quality in cancer diagnosis.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
December 01, 2014 - carcinoma of the head and
neck (SCCHN) constitutes approximately 90 percent of all
head and neck cancers … Cancer Institute’s Physician
Data Query Cancer Information Summary.8 The definitions
include cancer … Gupta et al. reported aggregated survival results in patients
with tumors in different sites. … Intensity-modulated radiation
therapy in head and neck cancers: an update. … Head and neck cancers.
J Nat Compr Cancer Netw. 2011 Jun 1;9(6):596-650.
PMID: 21636536.
9.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
August 01, 2015 - PBT
Tumor control and survival ��� ��� ���
Grade ≥2 late xerostomia* Significantly reduced incidence … , salivary gland dysfunction, swallowing dysfunction)
��� ��� ���
Effects of specific patient and tumor … needed to determine the comparative effectiveness of
IMRT, 3DCRT, SBRT, and PBT:
�– In achieving tumor … improving quality of life
�– In understanding how outcomes are affected by the
characteristics of the tumor … chemotherapy)
�� An important area of investigation is the potential
impact of human papillomavirus-positive tumors
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
December 01, 2009 - Layout 1
Background
Breast cancer is the second most common
malignancy of women, with over 180,000 … However, it is generally acknowledged
that early diagnosis and treatment of breast tumors
leads to improved … The
theoretical cohort of women includes 300 women with
malignant tumors and 700 women with benign lesions … Summary of key accuracy findings (Key Question 1)
Number of Number of
Number of malignancies invasive … missed Risk of expected per cancers
cancers malignancy 1,000 biopsy expected per Strength of
expected
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hcup-us.ahrq.gov/reports/statbriefs/sb132.jsp
May 01, 2012 - childhood cancers: 4 leukemias, cancer of the brain and nervous system, and cancer of the bone and … Increases were more modest for cancer of the bone and connective tissue, non-Hodgkin's lymphoma, cancers … , 21.0 percent were for cancer of the bone and connective tissue, 12.3 percent were for secondary malignancies … 21.0%
Secondary malignancies
9,100
12.3%
Cancer of brain and nervous system
8,800 … 1.1%
Malignant neoplasm without specification of site
700
1.0%
1 Stays for children ages
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
August 22, 2012 - and higher grade
tumors. … The percentage of women
with ER+ tumors was similar for the DCIS and invasive
cancer groups. … Tumors larger
than 1 cm and high-grade tumors were associated with
higher rates of HER2 testing except … Treatment targeted to ER+ tumors is very
effective for women with invasive cancers
and ER testing is … HER2 testing to manage patients
with breast cancer or other solid tumors.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/nmcMhEwWT9BncBBBQQN6Uf
December 01, 2015 - of breast cancer is modeled as a
continuously growing tumor. … Each tumor has a size (the fatal diameter, which differs between
tumors) at which diagnosis and treatment … Variation between tumors is modeled by probability
distributions of tumor growth, threshold diameter … The MISCAN-Fadia
continuous tumor growth model for breast cancer. … Number of cancers diagnosed is higher in B50–74 vs.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
August 09, 2021 - First, screening mammography has resulted in increased detection of
smaller tumors, and in countries … of PBI, such as larger tumor size (2-3 cm), high tumor grade, close margins, human
epidermal growth … recurrence (i.e., tumor bed
ipsilateral breast cancer recurrence, elsew here ipsilateral
breast cancer … Global cancer statistics 2020: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers … Non-Indexed Citations and Daily 1946 to June 29, 2021
Search Strategy:
# Searches
1 exp Breast Neoplasms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-mri-utilization_research.pdf
August 01, 2012 - The typical treatment for both DCIS and early invasive breast
cancer is surgical removal of the tumor … Rural refers to counties with
fewer than 2,500 people.15
Tumor size: We defined tumor size using the … Use was higher for women
with larger or higher grade tumors. … bilateral breast cancers. … In general, women with higher risk DCIS
(larger tumor size, higher grade disease, or
ER-negative tumors
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-1996
January 01, 1996 - Although the Pap smear can sometimes detect endometrial, vaginal, and other cancers, 3 , 4 its use as … cytologic diagnoses, false-negative diagnoses were made in 7.5% of smears with moderate dysplasia or frank malignancy … and invalid assumptions that an interval longer than 1 year may permit aggressive, rapidly growing cancers … recommended that the first two to three smears be obtained 1 year apart as a means of detecting aggressive tumors … Controversies in the management of low-grade cervical intraepithelial neoplasia.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
May 01, 2004 - Two large cohort studies using
transvaginal ultrasound screening reported that 59%
to 65% of ovarian cancers … were diagnosed in Stage
I.11,12 However, there is no evidence that detecting
earlier-stage tumors through … assumption that earlier
treatment leads to a 40% mortality reduction) would
yield a maximum of 4 additional cancers … American Cancer Society. Cancer Facts & Figures
2003. … Invasive epithelial
ovarian cancers in white women. Collaborative
Ovarian Cancer Group.
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psnet.ahrq.gov/web-mm/fluidity-diagnostic-wet-reads
April 24, 2018 - Although subsolid nodules are often malignant or premalignant, they usually give rise to malignancies … that behave more indolently than solid malignancies. … lung cancer. … September 26, 2012
Errors in the MRI evaluation of musculoskeletal tumors and tumorlike … May 1, 2011
Missed breast cancers at US-guided core needle biopsy: how to reduce
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psnet.ahrq.gov/issue/diagnostic-delays-and-errors-head-and-neck-cancer-patients-opportunities-improvement
March 14, 2022 - June 21, 2018
Diagnostic error in pediatric cancer. … October 9, 2017
Breast cancer screening in Denmark: a cohort study of tumor size and … January 23, 2017
Safety and diagnostic accuracy of tumor biopsies in children with cancer … errors and logistical breakdowns contributing to missed and delayed diagnoses of breast and colorectal cancers … October 10, 2012
Rates of new or missed colorectal cancers after colonoscopy and their
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MnkNvteY4Yg_8Jut4SayVN
July 02, 2002 - recommendation
The USPSTF found fair evidence that tamoxifen
and raloxifene may prevent some breast cancers … average, treating such women with tamoxifen for
5 years would prevent about 3 times as many
invasive cancers … women
enrolled in BCPT, the women in these trials were
younger, had more estrogen-receptor-negative
cancers … When effective, both raloxifene and
tamoxifen were effective only against estrogen
receptor-positive tumors … (0.8 cancers/1,000 women
taking placebo vs 3.1 cancers/1,000 women taking
tamoxifen for a median of
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-2002
December 01, 2002 - causes of this decline are uncertain. 5
Tumor grade appears to be a stronger predictor of prognosis … In studies of untreated prostate cancer, well‐differentiated tumors had low rates of metastasis or mortality … significant based on size and tumor grade, but which would not have progressed to clinical symptoms … . 3
In the absence of better data about which treatments are effective for which tumors, the USPSTF … for prostate, colorectal, and endometrial cancers.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-navigation-model-lung-cancer-rapid.pdf
December 01, 2018 - Lung cancer presents certain challenges which may not be relevant for patients with other
cancers, including … exp neoplasms, experimental/ or exp neoplasms, hormone-dependent/ or exp neoplasms, multiple primary … * or neoplasm* or blastoma* or carcinoma* or metastat*).tw,kf.
6 or/4-5
7 exp Lung Neoplasms/ or Bronchial … neoplasm ) OR AB
( cancer OR carcinoma OR neoplasm )
AND
( lung OR pulmonary OR bronchial ) OR AB … ") OR
(MH "Cancer Care Facilities"))
OR
( ( carcinoma OR neoplasm OR cancer ) OR AB (
carcinoma
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www.uspreventiveservicestaskforce.org/Home/GetFile/1/16255/collabmodelingbc/pdf
December 01, 2015 - of breast cancer is modeled as a
continuously growing tumor. … Each tumor has a size (the fatal diameter, which differs between
tumors) at which diagnosis and treatment … Variation between tumors is modeled by probability
distributions of tumor growth, threshold diameter … The MISCAN-Fadia
continuous tumor growth model for breast cancer. … Number of cancers diagnosed is higher in B50–74 vs.
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effectivehealthcare.ahrq.gov/products/liver-cancer/research-protocol
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psnet.ahrq.gov/issue/missed-breast-cancers-us-guided-core-needle-biopsy-how-reduce-them
March 25, 2020 - Review
Missed breast cancers at US-guided core needle biopsy: how to reduce them. … Missed breast cancers at US-guided core needle biopsy: how to reduce them. … Missed breast cancers at US-guided core needle biopsy: how to reduce them. … March 25, 2020
Changes in cancer detection and false-positive recall in mammography using … October 7, 2011
Errors in the MRI evaluation of musculoskeletal tumors and tumorlike