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121. Evidence Summary: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ovarian-cancer-screening
     February 13, 2018 - Tumors of the peritoneum: epithelial tumors of Müllerian type. … , increased risk of familial ovarian cancer, active nonovarian malignancy KQ1: Ovarian cancer (ovarian … , or any active malignancy KQ1: Ovarian cancer (ovarian, fallopian tube cancer) incidence and mortality … volume >10 cm 3 ; any solid area or papillary projection extending into the cavity of a cystic ovarian tumor … of any size; or any mixed (solid and cystic) component within a cystic ovarian tumor Notification

122. Some cancer experts see 'overdiagnosis,' question emphasis on early detection. | PSNet
     psnet.ahrq.gov/issue/some-cancer-experts-see-overdiagnosis-question-emphasis-early-detection
     June 19, 2019 - Newspaper/Magazine Article Some cancer experts see 'overdiagnosis,' question emphasis … of tumors that may never cause harm, this newspaper article discusses the impact of unnecessary tests … Researchers are working to design better tests to distinguish between benign abnormalities and cancers … May 26, 2021 A crisis of undiagnosed cancers is emerging in the pandemic’s second year … November 26, 2014 Missing a cancer diagnosis.

123. Head-Neck-Cancer-Update Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_consumer.pdf
     August 01, 2015 - � Radiation therapy: High-energy radiation beams are used to kill cancer cells in and around the tumor … Radiation therapy uses high-energy radiation beams to kill cancer cells in and around a tumor. … � It can shrink tumors, reduce some symptoms, and relieve pain. … that hits healthy tissues around the tumor. … The goal is to: � Target the tumor with the right amount (dose) of radiation � Limit the radiation

124. Cancer in Children | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/cancer-children

125. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/49870/psn-pdf
     August 10, 2019 - patients who used low-dose aspirin had markedly higher sensitivity for detecting advanced colorectal neoplasms … cancer screening.(13) A population cohort study found that 6% of colorectal cancers develop within … of the patient, family history of gastrointestinal neoplasia, and missed or incompletely excised lesions … or development of interval cancers. … Screening colonoscopy in very elderly patients: prevalence of neoplasia and estimated impact on life

126. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - PIVOT conducted in the US and primarily involved men with PSA detected tumors. … Nearly 80% of SPCG-4 subjects had T2 (palpable) tumors vs. only about 45% in PIVOT. P 59. … The report focuses only on T1 through T3a cancers. … , Reduces the risk of a second malignant neoplasms (SMN) in prostate patients compared with contemporary … Risk of secondary malignant neoplasms from proton therapy and intensity-modulated x- ray therapy for

127. Clinical Classifications for Health Policy Research: Hospital Inpatient Statistics, 1995
     hcup-us.ahrq.gov/reports/natstats/his95/appaa.htm
     September 01, 1998 - 20260 20261 20262 20263 20264 20265 20266 20267 20268 2340 2348 2349 7951 42 Secondary malignancies … 1975 1976 1977 1978 1980 1981 1982 1983 1984 1985 1986 1987 19881 19882 19889 43 Malignant … neoplasm without specification of site 1990 1991 44 Neoplasms of unspecified nature or uncertain … 2399 45 Maintenance chemotherapy, radiotherapy V580 V581 V661 V662 V671 V672 46 Benign … benign neoplasm V1272 2100 2101 2102 2103 2104 2105 2106 2107 2108 2109 2110 2111

128. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
     February 22, 2012 - and Endobronchial Obstruction Due to Advanced Lung Tumors I. … recurrence, noncancer-related mortality, and second malignancies.2, 3 Malignant Endobronchial Obstruction … Intraoperative seed placement for thoracic malignancy-A review of technique, indications, and published … '/exp OR ('lung neoplasms'/exp OR 'lung cancer'/exp AND ('non- small-cell' OR 'non-small cell' OR 'non … '/exp OR ('lung neoplasms'/exp OR 'lung cancer'/exp AND ('non- small-cell' OR 'non-small cell' OR 'non

129. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - leading cause of cancer deaths in men in the United States.1,2 Most patients have slow-growing tumors … lifetime risk of dying from the disease is only 3 percent.1,3,5 However, some patients have aggressive tumors … effectiveness of using PCA3 testing alone, or in combination with the standard prognostic workup (e.g., tumor … PCA3 score before radical prostatectomy predicts extracapsular extension and tumor volume. … PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates

130. Gastric-Cancers-Supplementary-App-I (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
     January 01, 2019 - meta-analysis supports existence of effect modification for immunotherapy by PD-L1 status in gastric cancer … Multiple other effect modifiers evaluated. 41436 MAGIC Primary tumor location Yes Overall survival Hazard … Multiple other effect modifiers evaluated. 47286 KEYNOTE-585 Primary tumor location Yes Overall survival … evaluating the correlation between TUBB3 expression and taxane-based chemotherapy for gastric and other cancers … Cut point for dichotomization of unclear clinical relevance. 43481 JACCRO GC-07 Tumor location within

131. G:CIRD565TQMothers able1.PDF (pdf file)
     hcup-us.ahrq.gov/reports/natstats/his96/table1.pdf
     February 11, 2011 - Benign neoplasm of uterus [46.] 222,765 0.64 $8,551 $5,702 $7,746 $10,317 3.0 0.0 … 0.0 43.8 2.16.2 Other and unspecified benign neoplasm 151,779 0.44 $13,848 $5,700 … 2.16.2.2 Benign neoplasm of colon 26,537 0.08 $13,071 $5,756 $9,785 $15,546 5.9 … 0.7 48.5 69.4 2.16.2.3 Benign neoplasm of the thyroid 12,419 0.04 $6,806 $4,265 $5,936 … $8,074 1.7 0.0 18.6 49.3 2.16.2.4 Benign neoplasm of cerebral meninges 12,413 0.04

132. Archived: Evidence Summary: Radiation-Induced Breast Cancer and Breast Cancer Death: Breast Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-radiation-induced-breast-cancer-and-breast-/breast-cancer-screening-january-2016
     January 11, 2016 - detection rates, and cancer stage at detection, we estimated thresholds at which tumors become screen-detectable … The effect of screening on breast cancer natural history was assessed by modeling continuous tumor growth … , in which tumors detected before they reached their fatal diameter were cured and those detected past … Tumour development, histology and grade of breast cancers: prognosis and progression. … The MISCAN-Fadia continuous tumor growth model for breast cancer.

133. Archived: Brief Evidence Update: Oral Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-update-2004/oral-cancer-screening-2004
     February 04, 2004 - The MEDLINE® search strategy combined the exploded MeSH® heading of Oral Neoplasm with Lip Neoplasm, … Tongue Neoplasm, and Pharynx Neoplasm and crossed the result with Mass Screening, yielding 88 articles … Forty-seven cancers (7 resultant deaths) were diagnosed in the intervention group and 16 cancers (9 resultant … Treatment of oral leucoplast, a form of pre malignancy, has been studied in RCT's with several modalities … Micronuclei, a biomarker for chemoprevention trials: results of a randomized study in oral pre-malignancy

134. Topic Brief: Accelerated Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-apbi-breast-cancer.pdf
     August 01, 2022 - patients with early stage breast cancer reduces tumor recurrence and increases survival.4 According … cancer stage, tumor size, tumor margin status, estrogen receptor status, etc. … Comparison of Treatment Costs for Breast Cancer, by Tumor Stage and Type of Service. … syndrome"/ or inflammatory breast neoplasms/ or triple negative breast neoplasms/ or unilateral breast … neoplasms/ (295124) 2 (breast adj5 (cancer* or carcinoma* or invasive or malignan* or noninvasive or

135. Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/BMh7ctXLmgRXhC4CVZGJNH
     April 01, 2015 - Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening Technical Report … Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening Prepared … Women with large breasts had higher risk of radiation-induced cancer (mean LAR, 265 cancers and 35 deaths … per 100,000 women; 95th percentile, 481 cancers and 63 deaths per 100,000 women) compared to other … women (mean LAR, 112 cancers and 15 deaths per 100,000 women; 95th percentile, 187 cancers and 24 deaths

136. Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFileByID/1932
     April 01, 2015 - Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening Technical Report … Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening Prepared … Women with large breasts had higher risk of radiation-induced cancer (mean LAR, 265 cancers and 35 deaths … per 100,000 women; 95th percentile, 481 cancers and 63 deaths per 100,000 women) compared to other … women (mean LAR, 112 cancers and 15 deaths per 100,000 women; 95th percentile, 187 cancers and 24 deaths

137. Archived: Addendum to Screening for Ovarian Cancer: Evidence Update for the U.S. Preventive Services Task Force Reaffirmation Recommendation Statement: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/addendum-to-screening-for-ovarian-cancer-evidence-update-for-the-us-preventive-services-task-force-reaffirmation-recommendation-statement/ovarian-cancer-screening-2012
     April 15, 2012 - via ultrasonography, serum tumor markers, or pelvic examination was not recommended (D recommendation … , serum tumor markers, or pelvic examination was not recommended (D recommendation) 3 . … cancer and ovarian tumors with uncertain behavior. … of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer … malignancy.

138. Cell-Free-Dna-Appendix-C-Prepub-Final (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
     January 01, 2025 - Neoplasia. 2023 Dec;46:100941. doi: 10.1016/j.neo.2023.100941. PMID: 37918207. … Validation cohort ("V") included 82 participants with GI cancers, 11 participants with benign tumors, … The diagnostic performance of the tumor markers for GI cancer screening (analysis 1) and whole-body cancer … Staging per TNM Classification of Malignant Tumors by Union for International Cancer Control, 8th ed. … Both new and recurrent: 1/35 Solid tumors: 19/35 (53%) Hematologic: 17/35 (47%) TP with new cancer:

139. Cell-Free-Dna-Final-App-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
     January 01, 2025 - Neoplasia. 2023 Dec;46:100941. doi: 10.1016/j.neo.2023.100941. PMID: 37918207. … Validation cohort ("V") included 82 participants with GI cancers, 11 participants with benign tumors, … The diagnostic performance of the tumor markers for GI cancer screening (analysis 1) and whole-body cancer … Staging per TNM Classification of Malignant Tumors by Union for International Cancer Control, 8th ed. … Both new and recurrent: 1/35 Solid tumors: 19/35 (53%) Hematologic: 17/35 (47%) TP with new cancer:

140. Colorectal-Cancer-Liver-Metastases-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
     December 01, 2012 - Most colorectal cancers are adenocarcinomas, meaning that they are a cancer of the epithelium originating … Is extended hepatectomy for hepatobiliary malignancy justified? … Extended hepatectomy in patients with hepatobiliary malignancies with and without preoperative portal … HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers. … Recommendations for radioembolization of hepatic malignancies using Yttrium-90 microsphere brachytherapy