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101. Screening for Lung Cancer (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/gpMtFCtW7cvssqc6wRuogm
     March 01, 2021 - Screening for Lung Cancer 1 www.uspreventiveservicestaskforce.org Clinician Summary of USPSTF … Recommendation Screening for Lung Cancer March 2021 The USPSTF recognizes that clinical decisions involve … The USPSTF has revised the recommended ages and pack-years for lung cancer screening. … If a person decides to be screened, refer them for lung cancer screening with low-dose CT, ideally to … a center with experience and expertise in lung cancer screening.

102. Archived: Final Evidence Summary: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary12/cervical-cancer-screening-2012
     October 18, 2011 - controlled trials (RCTs) (120,533 participants), primary HPV screening detected more cases of CIN grade 3 or cancers … Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV … Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial … neoplasia 3: a retrospective cohort study. … Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical

103. Overdiagnosis in Prostate Cancer Screening Decision Models: A Contextual Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16812/prostate-models-overdiagnosis/pdf
     May 01, 2018 - by CISNET as “computer models that operate at the level of individuals or smaller entities such as tumors … consists of tumor onset, time from tumor onset to diagnosis (i.e., sojourn times), and sensitivity … 3 natural history states (healthy, preclinical, clinical) Does not specify stage or grade of tumor … Sensitivity of screening test in an increasing function of time since tumor onset Mechanism … Lifetime Risk of Overdiagnosis (Overdiagnosed Cancer as a Proportion of Screen-Detected Cancers) by Screening

104. Archived: Final Research Plan: Skin Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
     July 17, 2014 - from skin cancer. … Key question 4 addresses whether skin cancer screening leads to earlier detection of skin cancer tumors … , specifically either an earlier stage tumor or one with less thickness. … Does visual screening for skin cancer lead to earlier detection of skin cancer compared with usual care … What is the association between earlier detection of skin cancer and skin cancer morbidity and mortality

105. Modeling Study: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/cervical-cancer-screening
     August 21, 2018 - describe underlying disease status, including HPV infection, precancer (ie, cervical intraepithelial neoplasia … Human papillomavirus genotype–specific prevalence across the continuum of cervical neoplasia and cancer … Saraiya M, Unger ER, Thompson TD, et al; HPV Typing of Cancers Workgroup. … US assessment of HPV types in cancers: implications for current and 9-valent HPV vaccines. … cancers).

106. Benefits and Harms of Computed Tomography Lung Cancer Screening Programs for High Risk Populations (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkeQEwKRWULreuWecXG8S-
     July 01, 2013 - compared with the stage-specific survival if the same tumor had been diagnosed clinically, later … curative treatment fails, the survival of the patient will equal the survival in the case in which the tumor … Model F estimates cure rates that depend on sex, tumor stage, and histology. … For detected cancers in Model U, time to death from lung cancer is based on survival models that define … Model S estimates the probability of lethal metastases as a function of tumor size, histology, and

107. Screening for Breast Cancer: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/zESNSGqmKFpJWqNb573WXC
     November 01, 2009 - Better understanding of certain facets of tumor biol- ogy is needed, particularly how age, race, breast … density, and other factors may predispose certain women toward tumors with faster growth rates and greater … mam- mography seen in trials presumably results from the early detection of smaller, earlier-stage tumors … Knowledge of what deter- mines the rapidity with which invasive cancer can spread (tumor characteristics … and economic efficiency of inter- ventions to increase screening for breast, cervical, and colorectal cancers

108. Archived: Modeling Report: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report/lung-cancer-screening-december-2013
     July 30, 2013 - compared with the stage-specific survival if the same tumor had been diagnosed clinically, later in … curative treatment fails, the survival of the patient will equal the survival in the case in which the tumor … Model F estimates cure rates that depend on sex, tumor stage, and histology. … For detected cancers in Model U, time to death from lung cancer is based on survival models that define … Model S estimates the probability of lethal metastases as a function of tumor size, histology, and sex

109. Cancer Older Adults (pdf file)
     www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/cancer_older_adults.pdf
     September 28, 2012 - KEY WORDS: older adults; cancer screening; patient preferences. … and prostate cancer decision making. … Breslau, PhD at the National Cancer Institute, Dr. … Screening for Cervical Cancer: Recommendations and Rationale. … Outcomes Assessment in Cancer: Measures, Methods, and Applications.

110. Evidence Summary: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/cervical-cancer-screening
     August 21, 2018 - Main Outcomes and Measures: Invasive cervical cancer; cervical intraepithelial neoplasia (CIN); false-positive … Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial … Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer … Socioeconomic, rural-urban, and racial inequalities in US cancer mortality: part I—all cancers and lung … cancer and part II—colorectal, prostate, breast, and cervical cancers.

111. Archived: Bladder Cancer in Adults: Screening, 2004 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-screening-2004
     June 07, 2004 - Email Print archived Final Recommendation Statement Bladder Cancer … screening would be small, at best, for the following reasons: there is fair evidence that many of the cancers … tests—such as microscopic urinalysis, urine dipstick, urine cytology, or such new tests as bladder tumor … antigen (BTA) or nuclear matrix protein (NMP22) immunoassay—can detect bladder cancers that are clinically … Smoking increases the risk for bladder cancer; about 50% of all cases of bladder cancer occur in current

112. Recommendation: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
     March 09, 2021 - Risk prediction models also were associated with increased the number of over diagnosed lung cancers, … Initially, the NLST reported 119 additional lung cancers (1060 total cancers with LDCT vs 941 with chest … (344 cancers in the LDCT group vs 304 in the control group) were reported in the LDCT group after the … being over diagnosed lung cancers vs 6.0% lung cancers being overdiagnoses with the 2021 screening program … Extrapulmonary findings and malignancies in participants screened with chest CT in the National Lung

113. Final Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
     March 17, 2022 - Share to Email Print in progress Final Research Plan Cervical Cancer … What are the comparative harms of different cervical cancer screening strategies (i.e., test, mode of … or morbidity/mortality from cervical cancer (e.g., by race and ethnicity, income/socioeconomic status … (squamous cell carcinoma or adenocarcinoma) Mortality (all-cause or cervical cancer) Quality of … Abbreviations: CIN2+=cervical intraepithelial neoplasia grade 2; CIN3+=cervical intraepithelial neoplasia

114. Screening for Colorectal Cancer: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/n4sdjxShTApRE6UxvyYuzG
     November 01, 2008 - Although single test performance is an important issue in the detection of colorectal neoplasia, the … Unfortunately, data that permit assessment and comparison of screening methods to detect colorectal neoplasia … The lead time between the detection and treatment of colorec- tal neoplasia and a mortality benefit … insufficient evi- dence to assess the sensitivity and specificity of fecal DNA testing for colorectal neoplasia … total number of colonoscopies included those resulting from surveillance after detection of colorectal neoplasia

115. Summary of USPSTF Draft Recommendation: Screening for Cervical Cancer (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3UuREAobGvgLbE_FBAnrYQ
     January 13, 2025 - Cervical cancer is a cancer that begins in the cells of the cervix (which is the lower part of the uterus … cervix and do not have a history of a high-grade precancerous lesion (i.e., cervical intraepithelial neoplasia … • Cervical cancer is one of the most preventable and treatable types of cancer. … • Screening for cervical cancer saves lives and helps find cancer early when it is treatable. … ) What Is Cervical Cancer?

116. Screening for Colorectal Cancer: Clinical Summary of USPSTF Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/DcUgaNRhU6PvJWXqqsa8X7
     Screening for Colorectal Cancer: Clinical Summary of USPSTF Recommendation Figure. … Screening for Colorectal Cancer: Clinical Summary Population Adults aged 50 to 75 y Adults aged 76 … to 85 y Recommendation Screen for colorectal cancer starting at age 50 y. … Grade: A The decision to screen for colorectal cancer is an individual one. … excision or simple polypectomy for tumors limited to the colonic mucosa or surgical resection (via

117. Hdzuzdx4Qlnc2Pjbkfwquw (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/hDZUZdx4qLNc2PjbkfWQuw
     April 01, 2016 - for invasive cancers only). … Those with HER2-positive tumors also re- ceived trastuzumab. … or the number of early invasive cancers that might be nonprogressive. … The MISCAN-Fadia continuous tumor growth model for breast cancer. … Tumor microRNA expression profiling identifies circulating microRNAs for early breast cancer detection

118. Effects of Mammography Screening Under Different Screening Schedules: Model Estimates of Potential Benefits and Harms (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/r3f2G_ReqS8tN48szHPCxt
     November 01, 2009 - Some groups model breast can- cer in stages, but 3 (models E, S, and W) use tumor size and tumor growth … Age, estrogen receptor status, and tumor size– or stage–specific treatment have independent effects on … Slow-growing tumors are much more common than fast-growing tumors, and the ratio of slow- to fast-growing … The MISCAN-Fadia continuous tumor growth model for breast cancer. … Summary of Base-Case Input Data Sources* Model Inputs Data Sets BCSC SEER 9 Registry Connecticut Tumor

119. Screening for Cervical Cancer (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/TEqfQsqZ92eykPeTQBZx-h
     Screening for Cervical Cancer SCREENING FOR CERVICAL CANCER CLINICAL SUMMARY OF U.S. … hysterectomy with removal of the cervix and with no history of high-grade precancer or cervical cancer … and early-stage asymptomatic invasive cervical cancer. … Early-stage cervical cancer may be treated with surgery (hysterectomy) or chemoradiation. … cancer susceptibility.

120. Archived: Cervical Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2012
     March 15, 2012 - cervix and who do not have a history of a high-grade precancerous lesion (cervical intraepithelial neoplasia … Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical … intraepithelial neoplasia: a randomised controlled trial. … Human papillomavirus DNA testing for the detection of cervical intraepithelial neoplasia grade 3 and … Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer