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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
    February 01, 2012 - is one of the most common malignancies of women, with approximately 200,000 new cases diagnosed … every year in the United States.1 Some breast cancers are identified by physical examination (either … Women with readily treatable early-stage cancers who mistakenly get triaged into “return to normal … Prospective sonographic study of 3093 breast tumors. J Ultrasound Med. 1999 May;18(5):363-70. … D galactose-based signal-enhanced color Doppler sonography of breast tumors and tumorlike lesions.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d1.xlsx
    January 01, 2024 - of prostate cancer, any malignancy diagnosed within 5 years of entry except for nonmelanoma skin cancer … (except basal cell carcinoma or other tumors within the past five years) Patients with nodal involvement … or prior pelvic RT/prostatectomy History of other malignancies (within five years, with noted exceptions … Prior malignancies, presence of small-cell, neuroendocrine or transitional-cell carcinoma in the biopsy … other than nonmetastatic skin cancers or early stage small lymphocytic lymphoma within the last 5 years
  3. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
    December 01, 2021 - percent across patient populations.7-9 However, risk of malnutrition varies substantially by patient and tumor … characteristics, including age at diagnosis, tumor type, stage of disease, type of cancer treatment … (such as Head and Neck, Breast, Multiple Cancers, etc.) and report the intervention comparisons and … emia* or melanoma* or myeloma* or neoplasm* or radiotherap* or radiation therap*).ti,ab. … or exp Neoplasms/ or chemoprevention/ or chemoradiotherapy/ or chemoradiotherapy, adjuvant/ or chemotherapy
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
    December 01, 2014 - carcinoma of the head and neck (SCCHN) constitutes approximately 90 percent of all head and neck cancersCancer Institute’s Physician Data Query Cancer Information Summary.8 The definitions include cancer … Gupta et al. reported aggregated survival results in patients with tumors in different sites. … Intensity-modulated radiation therapy in head and neck cancers: an update. … Head and neck cancers. J Nat Compr Cancer Netw. 2011 Jun 1;9(6):596-650. PMID: 21636536. 9.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
    August 01, 2015 - PBT Tumor control and survival ��� ��� ��� Grade ≥2 late xerostomia* Significantly reduced incidence … , salivary gland dysfunction, swallowing dysfunction) ��� ��� ��� Effects of specific patient and tumor … needed to determine the comparative effectiveness of IMRT, 3DCRT, SBRT, and PBT: �– In achieving tumor … improving quality of life �– In understanding how outcomes are affected by the characteristics of the tumor … chemotherapy) �� An important area of investigation is the potential impact of human papillomavirus-positive tumors
  6. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
    December 01, 2009 - Layout 1 Background Breast cancer is the second most common malignancy of women, with over 180,000 … However, it is generally acknowledged that early diagnosis and treatment of breast tumors leads to improved … The theoretical cohort of women includes 300 women with malignant tumors and 700 women with benign lesions … Summary of key accuracy findings (Key Question 1) Number of Number of Number of malignancies invasive … missed Risk of expected per cancers cancers malignancy 1,000 biopsy expected per Strength of expected
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
    August 22, 2012 - and higher grade tumors. … The percentage of women with ER+ tumors was similar for the DCIS and invasive cancer groups. … Tumors larger than 1 cm and high-grade tumors were associated with higher rates of HER2 testing except … Treatment targeted to ER+ tumors is very effective for women with invasive cancers and ER testing is … HER2 testing to manage patients with breast cancer or other solid tumors.
  8. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
    August 09, 2021 - First, screening mammography has resulted in increased detection of smaller tumors, and in countries … of PBI, such as larger tumor size (2-3 cm), high tumor grade, close margins, human epidermal growth … recurrence (i.e., tumor bed ipsilateral breast cancer recurrence, elsew here ipsilateral breast cancer … Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers … Non-Indexed Citations and Daily 1946 to June 29, 2021 Search Strategy: # Searches 1 exp Breast Neoplasms
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-mri-utilization_research.pdf
    August 01, 2012 - The typical treatment for both DCIS and early invasive breast cancer is surgical removal of the tumor … Rural refers to counties with fewer than 2,500 people.15 Tumor size: We defined tumor size using the … Use was higher for women with larger or higher grade tumors. … bilateral breast cancers. … In general, women with higher risk DCIS (larger tumor size, higher grade disease, or ER-negative tumors
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-navigation-model-lung-cancer-rapid.pdf
    December 01, 2018 - Lung cancer presents certain challenges which may not be relevant for patients with other cancers, including … exp neoplasms, experimental/ or exp neoplasms, hormone-dependent/ or exp neoplasms, multiple primary … * or neoplasm* or blastoma* or carcinoma* or metastat*).tw,kf. 6 or/4-5 7 exp Lung Neoplasms/ or Bronchial … neoplasm ) OR AB ( cancer OR carcinoma OR neoplasm ) AND ( lung OR pulmonary OR bronchial ) OR AB … ") OR (MH "Cancer Care Facilities")) OR ( ( carcinoma OR neoplasm OR cancer ) OR AB ( carcinoma
  11. effectivehealthcare.ahrq.gov/products/liver-cancer/research-protocol
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
    January 31, 2023 - Partial Breast Irradiation for Breast Cancer. Comparative Effectiveness Review No. 259. … • One reviewer suggested changing the terminology “ipsilateral breast tumor recurrence (IBTR)” to … size, tumor grade) in Appendix Table J subgroup analyses. … The results and discussion sections describe findings of the analysis of tumor size. … state that clinicians can consider treating with 26Gy in 5 fractions using mini-tangents for larger tumors
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
    February 01, 2008 - e.g., Gleason score, tumor volume, screen vs. clinically detected tumors) affect the outcomes of interventions … How do tumor characteristics, e.g., Gleason score, tumor volume, screen vs. clinically detected tumors … Men with low-grade prostate cancers had a minimal risk of dying from prostate cancer (7 percent with … Low • The risk of overall or prostate cancer death over 10 years for PSA-detected prostate cancers according … High • Screening with PSA testing detects more prostate cancer and cancers of smaller volume, earlier
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - The prostate cancer antigen-3 gene (PCA3) has recently been found to be overexpressed in prostate cancers … research question would be to determine if the trade-off between reduction in biopsies and missed cancers … and what is learned through the studies in Research Question 2.1 about likely behavior of cancers … Can intermediate outcomes, such as cancer classifications of aggressive or indolent tumors be properly … PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-e.xlsx
    June 25, 2025 - E-1. OS LT Table E-1. Overall survival league table Pre-op Fluoro+Plat+Taxane + Post-op Fluoro . . . . . . 0.76 [0.55; 1.05] . . . . . . . . . 1.03 [0.51; 2.09] Periop Fluoro+Plat+Taxane+Antiangio 0.92 [0.55; 1.53] . . . . . . . . . . . . . . 0.95 [0.58; 1.55] 0.92 [0.55; 1.53] Periop Fluoro+Plat+Taxane . 1.05 [0.5…
  16. 04-E029-1 Summary (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
    December 01, 2011 - The cancer is usually localized, and most tumors have low histological grades and low Gleason scores. … low-risk tumors. … cancer patients with other primary tumors were consistently less likely to die of prostate cancer compared … Tumor grade Three studies reported information on prostate cancer mortality stratified by tumor grade … The two studies reporting on T1/T2 tumors both demonstrated a decrease of T1a/T1b tumors and T2a tumors
  17. effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
    September 01, 2020 - Effects may not vary by patient or tumor factors. … one of the most frequently diagnosed cancers among U.S. men (191,930 new cases) and the second leading … cause of cancer death (33,330).1 In 90 percent of newly diagnosed cancers, the disease is confined … Effects may not vary by patient or tumor risk factors. … Age and tumor risk category may be important effect modifiers.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
    May 02, 2025 - Recurrent cancer, metastatic cancer, early stage (T1aN0 and T1bN0), stage 4 cancer, GEJ cancer patients … stromal tumors (GIST), neuroendocrine tumors, gastric lymphoma, MALToma, other rare gastric cancers … To reduce clinical heterogeneity, we will analyze studies of patients with resectable tumors or who … ://effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf https: … * OR carcinoma* OR malignan* OR neoplas* OR tumor* OR tumour*)):ab,ti,kw) 2 'cancer palliative therapy
  19. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-radiation-therapy-bone-metastases.pdf
    August 01, 2022 - Which patient characteristics (e.g., age, sex, socioeconomic status, histology of the primary tumor) … Consider patient characteristics (e.g., age, sex, socioeconomic status, histology of the primary tumor … The Role of Palliative Radiotherapy in the Treatment of Spinal Bone Metastases from Head and Neck Tumors-A … Cancers (Basel). 2020 Jul 18;12(7):18. doi: https://dx.doi.org/10.3390/cancers12071950. … Palliative Radiation Therapy for Bone Metastases in Neuroendocrine Neoplasms.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
    February 07, 2025 - Recurrent cancer, metastatic cancer, early stage (T1aN0 and T1bN0), stage 4 cancer, GEJ cancer patients … stromal tumors (GIST), neuroendocrine tumors, gastric lymphoma, MALToma, other rare gastric cancers … To reduce clinical heterogeneity, we will analyze studies of patients with resectable tumors or who … Key Informants https://effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf … * OR carcinoma* OR malignan* OR neoplas* OR tumor* OR tumour*)):ab,ti,kw) 2 'cancer palliative therapy

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