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41. Treatment of Non-metastatic Muscle-invasive Bladder Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/bladder-cancer-muscle-invasive/research-protocol
    July 21, 2014 - Stage 2 cancers are muscle-invasive, and higher stage cancers invade beyond the muscle layer into surrounding … Stage T4b cancer, in which the tumor has spread to the pelvis or abdominal wall, bladder cancer involving … Approximately 25 percent of newly diagnosed bladder cancers present as stage 2 or higher tumors. 6 Once … These include the stage of the cancer, tumor grade, whether the tumor is an initial tumor or a recurrence … and Treatment of Non-metastatic Muscle-invasive Bladder Cancer exp Urinary Bladder Neoplasms/ (42649

42. Data Points #16: Changes across time and geography in the use of prostate radiation technologies for newly diagnosed older cancer patients: 2006-2008 | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-radiation/research
    November 30, 2012 - outcomes, especially in higher risk tumors, although evidence is lacking. … Prior examinations of the same database have shown tumor characteristics such as size or stage to be … Higher doses of CRT are associated with lower tumor recurrence rates. … If CRT becomes less accessible, we may expect IMRT use to increase in other tumors, perhaps even in tumors … Monitoring IMRT use should be a priority for these other cancers as well as for groups of prostate cancer

43. Liver-Cancer Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - Executive Summary Background and Objectives Hepatocellular carcinoma (HCC) is the most common primary malignant … neoplasm of the liver, usually developing in individuals with chronic liver disease or cirrhosis. … Worldwide, it is the fifth most common cancer and the third most common cause of cancer death.1 There … National Cancer Institute. Liver Cancer. www.cancer.gov/ cancertopics/types/liver. … SEER Cancer Statistics Review, 1975-2010.

44. Liver-Cancer-Therapy Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
    November 28, 2012 - Unlike most solid tumors, the future incidence of and mortality rate due to HCC are projected to increase … using the following string of search terms: "Carcinoma, Hepatocellular"[Mesh] OR (hepatocellular AND (neoplasm … * OR cancer OR cancers OR carcinoma)) AND Unresectable OR nonresectable OR inoperable OR irresectable … comparative studies, and case series by using the following string of search terms: hepatocellular AND (neoplasm … * OR cancer OR cancers OR carcinoma) AND (unresectable OR nonresectable OR inoperable OR irresectable

45. Diagnosis and Treatment of Non-muscle Invasive Bladder Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/diagnosis-and-treatment-of-non-muscle-invasive-bladder-cancer
    October 03, 2012 - , cystoscopy, urine cytology, urine-based biomarkers, transurethral resection of bladder tumor (TURBT … How do tumor characteristics (stage, grade, multiplicity, size, molecular and genetic alterations) predict … perhaps replace cytology and cystoscopy in the diagnosis and surveillance of patients with urothelial cancers … Genetic and epidemiological evidence indicates that African Americans may have a more aggressive form of malignancy … for 90% of all malignant tumors.

46. Liver-Cancer-Therapy Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
    May 01, 2013 - One study reported cancer-free survival (from time of study treatment to local tumor progression), extrahepatic … Authors varied in how these tumor characteristics were described: mean number and size of tumors, median … number and size of tumors, range of number and size of tumors, percent solitary and nonsolitary tumors … Hepatobiliary Cancers. Version 2. 2010. … Treatment of large and/ or multiple hepatic malignancies: open surgical approaches of radiofrequency

47. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - (e.g., lung, prostate, breast) and uncommon cancers (e.g., skull base tumors, uveal melanomas). … cancer) • Head and neck cancers, including malignancies of the brain (e.g., glioblastoma); of the … the sclera for some ocular cancers or in the uterus for some gynecologic malignancies), or may be directly … ), and cancers of the head and neck (brain tumors, and tumors arising from skull base, cervical spine … Treated cancers included malignant tumors in the head, neck and spine, non- small cell lung cancer, prostate

48. Bladder-Cancer-Muscle-Invasive Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-muscle-invasive_research-protocol.pdf
    July 21, 2014 - Stage 2 cancers are muscle-invasive, and higher stage cancers invade beyond the muscle layer into surrounding … Stage T4b cancer, in which the tumor has spread to the pelvis or abdominal wall, bladder cancer involving … Approximately 25 percent of newly diagnosed bladder cancers present as stage 2 or higher tumors.6 Once … These include the stage of the cancer, tumor grade, whether the tumor is an initial tumor or a recurrence … and Treatment of Non- metastatic Muscle-invasive Bladder Cancer 1. exp Urinary Bladder Neoplasms/

49. Rapid Response: Efficacy of Dental Services for Reducing Adverse Events in Those Receiving Chemotherapy for Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-chemotherapy-dental.pdf
    July 01, 2023 - The cancer conditions included acute leukemias, clinically advanced multiple myeloma, solid tumors with … Management of the neck in early oral cancers: Is the verdict out? … potential dental focal infection before the first cycle of chemotherapy in patients with hematologic malignancy … searched: December 16, 2022 1 Bone Marrow Transplantation/ or exp Immunosuppression Therapy/ or exp Neoplasms … leukemia* or lymphom* or malig* or neoplas* or onco* or radiat* or radiotherap* or "radio-therap*" or tumor

50. Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - non-dermatologic malignancy (174,650 new cases) and the second leading cause of cancer death (31,620 … With AS, tumors are not immediately removed, irradiated, or ablated.3, 4 Instead, tumors are monitored … Stage 1 T2= tumor Stage 2 T3= tumor Stage 3 T4= tumor Stage 4 WMD= weighted mean differences WW … / (121506) 2 (prostat* and (neoplasm* or cancer* or carcinoma*)).ti,ab. (142514) 3 watchful … / (9241) 2 (prostat$.ti,ab. or Prostate/) and (cancer.ti,ab. or Neoplasms/ or neoplasm$.mp. or

51. Emerging Approaches to Diagnosis and Treatment of Non-Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol
    July 21, 2014 - Stage 2 cancers are muscle-invasive, and higher stage cancers invade beyond the muscle layer into surrounding … . 7 As many as 70 percent of Non-MIBC tumors will recur after initial treatment, with a 10-20 percent … These include the stage of the cancer, tumor grade, whether the tumor is an initial tumor or a recurrence … treatment decision-making, based on available prognostic factors including grade, stage, number and size of tumors … and Treatment of Non-metastatic Muscle-invasive Bladder Cance r exp Urinary Bladder Neoplasms/ (

52. Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/cancer/

53. Key Questions - Optimal Medical Treatments for Non-Metastatic Gastric Cancers (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancer-key-questions.pdf
    January 01, 2020 - Key Questions - Optimal Medical Treatments for Non-Metastatic Gastric Cancers Optimal Medical Treatments … for Non-Metastatic Gastric Cancers Background Gastric cancer is the fifth most common cancer worldwide … , gastrointestinal stromal tumors (GIST)).. … rare gastric cancers Interventions KQ 1 KQ 2 KQ 3. … Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers

54. Project Title: Evaluation of Suspicious Skin Lesions Using Non-Invasive Diagnostic Techniques, a Technical Brief (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-lesions-evaluation_research-protocol.pdf
    August 23, 2010 - cancer in men and women, accounting for nearly half of all malignancies. … examine how these emerging non-invasive imaging modalities could be used to help diagnose cancerous tumors … whether or not patients have a history of other malignancies. … The rationale for this is the growing recognition of skin cancer as a leading form of second malignancy … Association of nonmelanoma skin cancer with second malignancy. Cancer 2004 January 1;100(1):130-8.

55. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - How do tumor characteristics affect outcomes? … volume to identify low-, intermediate-, and high risk tumors. … OR "prostate cancer" AND Limits: Meta-Analysis OR prostatic neoplasms OR "prostate cancer" AND … OR "prostate cancer" AND prostate-specific antigen OR "tumor characteristics" OR "tumor volume" OR … volume to identify low-, intermediate-, and high risk tumors.

56. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - How do tumor characteristics affect outcomes? … volume to identify low-, intermediate-, and high risk tumors. … OR "prostate cancer" AND Limits: Meta-Analysis OR prostatic neoplasms OR "prostate cancer" AND … OR "prostate cancer" AND prostate-specific antigen OR "tumor characteristics" OR "tumor volume" OR … volume to identify low-, intermediate-, and high risk tumors.

57. Management of Renal Masses and Localized Renal Cell Carcinoma: Current State of the Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
    July 01, 2017 - Renal cell carcinoma accounts for more than 94 percent of kidney malignancies. … treatment for patients with clinical stage T1a tumors (≤4 cm in diameter) and T1b tumors (4–7 cm) … (9,401) A positive relationship between tumor size and malignancy risk was found. 1.326 (1.220 to … and malignancy risk was found. … potential of tumors treated with RN.

58. Methods Research Report - Progression-Free Survival: What Does It Mean for Psychological Well-Being or Quality of Life? (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/survival-quality_research.pdf
    April 01, 2013 - "[Mesh] OR (breast AND (cancer OR cancers OR neoplasms OR carcinoma*)) AND ("progression-free survival … "[Mesh] OR (breast AND (cancer OR cancers OR neoplasms OR carcinoma*)) AND ("progression-free survival … "[Mesh] OR (breast AND (cancer OR cancers OR neoplasms OR carcinoma*)) AND ("progression-free survival … "[Mesh] OR ((ovary OR ovarian) AND (cancer OR cancers OR neoplasms OR carcinoma*))) AND ("progression-free … ") AND (cancer OR cancers OR carcinoma* OR neoplasms))) AND ("progression-free survival" OR "time to

59. Radiotherapy Treatments for Head and Neck Cancer Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_disposition.pdf
    December 09, 2014 - , not salivary gland cancers. … Listing patients with salivary gland cancers as head and neck cancers is understandable since they … Therefore, because use of brachytherapy alone for primary management of head and neck malignancies … Historically, it has been used extensively in many tumor types, including head and neck cancer. … Therefore, because use of brachytherapy alone for primary management of head and neck malignancies

60. Prostate-Cancer-Therapies-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
    December 01, 2014 - localized prostate cancer.2 After biopsy confirms the presence of the cancer, pathologists report tumor … classification is based on the extent of primary tumor (T stages), whether cancer has spread to the … Clinicians make pretreatment assessment of whether prostate cancer is localized by determining tumor … Ten to 15 years ago, prostate cancers were primarily detected by digital rectal examination or tissue … Currently, the vast majority of prostate cancers detected in the United States are found by PSA testing