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281. Anticoagulation for Venous Thromboembolic Events in Patients with Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cancer-venous-thrombosis-anticoagulation/abstract
     December 01, 2019 - Evidence Reports Anticoagulation for Venous Thromboembolic Events in Patients with Cancer … cancer patients using Medicare claims. … Evaluating outcomes for complicated patients like those with advanced cancer and VTE can be difficult … Project Timeline Anticoagulation for Venous Thromboembolic Events in Patients with Cancer Dec 15 … https://effectivehealthcare.ahrq.gov/products/cancer-venous-thrombosis-anticoagulation/abstract

282. Bile Duct Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/bile-duct-cancer
     Home Health Topics B Bile Duct Cancer … U V W X Y Z Health Topics Bile Duct Cancer … Bile duct cancer is rare. … Cancer of the bile duct outside of the liver is much more common. … NIH: National Cancer Institute Source https://medlineplus.gov/bileductcancer.html

283. Cervical Cancer Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/cervical-cancer-screening
     Cancer screening is looking for cancer before you have any symptoms. … Cancer found early may be easier to treat. … With the Pap test, the lab checks the sample for cancer cells or abnormal cells that could become cancer … It can sometimes lead to cancer. … Cervical cancer screening has risks.

284. Prostate Cancer Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/prostate-cancer-screening
     Cancer screening is looking for cancer before you have any symptoms. … Cancer found early may be easier to treat. … There is no standard screening test for prostate cancer . … Your PSA level may be high if you have prostate cancer. … Prostate cancer screening has risks: Finding prostate cancer may not improve your health or help

285. Male Breast Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/male-breast-cancer
     Description Although breast cancer is much more common in women, men can get it too. … Breast lumps usually aren't cancer. However, most men with breast cancer have lumps. … include exposure to radiation, a family history of breast cancer, and having high estrogen levels, which … Treatment for male breast cancer is usually a mastectomy , which is surgery to remove the breast. … NIH: National Cancer Institute Source https://medlineplus.gov/malebreastcancer.html

286. Comparative Effectiveness of Initial Chemotherapy for Advanced Non-Small Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lung-cancer-chemotherapy/abstract
     November 01, 2017 - Comparative Effectiveness of Initial Chemotherapy for Advanced Non-Small Cell Lung Cancer … Comparative Effectiveness of Initial Chemotherapy for Advanced Non-Small Cell Lung Cancer … 2013 Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non–Small-Cell Lung Cancer … Comparative Effectiveness of Initial Chemotherapy for Advanced Non-Small Cell Lung Cancer … https://effectivehealthcare.ahrq.gov/products/lung-cancer-chemotherapy/abstract  

287. Disposition of Comments: Technical Brief No. 39_Disparities and Barriers to Pediatric Cancer Survivorship Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
     March 01, 2021 - Additionally, the final draft should note where studies include both pediatric and adult onset cancers … based on cancer onset by age. … alleviate disparities among this population who are burdened by the adverse sequelae of their prior malignancy … Medical Care in Long-Term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor … kidney failure, liver disease, osteopenia and osteoporosis, neurocognitive deficits, and secondary malignancies

288. Chapter 11: Challenges in and Principles for Conducting Systematic Reviews of Genetic Tests Used as Predictive Indicators | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-genetic/methods
     December 01, 2019 - recurrence, a test to evaluate the tumor genome of surgically excised tumors from patients with breast … Similarly, BRCA mutations can increase the risk of a number of cancers, including breast, ovarian, prostate … Tumor specimens will often contain normal cells from the patient as well as tumor cells. … An EPC report on HER2 testing to manage patients with breast cancer and other solid tumors provides a … HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors/Technology Assessment No. 172

289. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/b
     B B Vitamins Back Injuries Back Pain Bacterial Infections Benign Tumors … Disorders Blood Pressure Medicines Blood Thinners Blood Transfusion and Donation Body Weight Bone Cancer … Bone Marrow Diseases Botox Botulism Bowel Incontinence Bowel Movement Brain Diseases Brain Tumors … Breast Cancer Breast Diseases Breast Reconstruction Breastfeeding Breathing Problems Bronchial

290. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/B
     B B Vitamins Back Injuries Back Pain Bacterial Infections Benign Tumors … Disorders Blood Pressure Medicines Blood Thinners Blood Transfusion and Donation Body Weight Bone Cancer … Bone Marrow Diseases Botox Botulism Bowel Incontinence Bowel Movement Brain Diseases Brain Tumors … Breast Cancer Breast Diseases Breast Reconstruction Breastfeeding Breathing Problems Bronchial

291. Nutrition as Prevention for Improved Cancer Outcomes | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/improved-cancer-outcomes
     October 04, 2021 - SHARE: Nutrition as Prevention for Improved Cancer

292. Comparative Effectiveness of Treatments for Cryptorchidism | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/undescended-testicle/research-protocol
     December 01, 2019 - Longer term consequences of cryptorchidism include testicular malignancy and infertility/subfertility … , with stronger evidence for the etiologic role of cryptorchidism in malignancy than in disordered fertility … between cryptorchidism and testicular cancer. … An estimated 10 percent of all testicular tumors develop from an undescended testis, 9 and the relative … risk of incidence of a testicular tumor is about 40 times greater in men with cryptorchidism when compared

293. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - not useful unless it identifies high-grade cancers. … Same with the designation for clinically “insignificant” cancers based on an examination of tumors found … The ability to discriminate indolent from significant cancers is covered only by KQ3. … it is not possible to determine the extent to which the PCA3 and comparators are identifying the tumors … to be rewarding to determine if the test result can give reasonable predictive value for high-grade tumors

294. Disposition of Comments_Models of Care That Include Primary Care for Adult Survivors of Childhood Cancer: A Realist View (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/childhood-cancer-disposition-comments.pdf
     February 16, 2022 - survivors or adult survivors of adult cancers. … survivors of adult cancers. 6 Peer Reviewer #1 Results Consider including a greater discussion about … For example, we did not exclude studies of adult survivors of adult cancers. … Also, unlike survivors of adult cancers, survivors of childhood cancers transition not just from oncology … and were forced to supplement with evidence from adult survivors of adult-onset cancers.

295. Can screening among the general adult male population for elevated PCA3 (also known as DD3) gene expression, to identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/can-screening-among-the-general-adult-male-population-for-elevated-pca3-also-known-as-dd3-gene-expression-to-identify-those-at-risk-for-prostate-cancer-who-may-be-candidates-for-prostate-biopsy-reduce-morbidity-and-mortality
     November 01, 2017 - you would like to see compared: Use of commercially available PCA3 expression assays for prostate cancer … Interested in improved health related outcomes resulting from improved/earlier detection of prostate cancer … May lead to unnecessary follow-up for men who are asymptomatic or have slowly progressing prostate cancer … Prostate cancer is among the most frequently diagnosed and deadliest cancers among men in the U.S. … Project Timeline PCA3 Testing in the Diagnosis and Management of Prostate Cancer

296. Comparative Effectiveness of Non-Invasive Diagnostic Tests for Breast Abnormalities – An Update of a 2006 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/breast-abnormalities-tests-update/research-protocol
     December 01, 2019 - Breast cancer is the second most common malignancy of women. 2 The American Cancer Society estimates … Biopsy should be considered. 5 = Highly suggestive of malignancy. … Appropriate action should be taken. 6 = Known biopsy-proven malignancy. … delay that may allow the tumor to spread and become life-threatening. … likelihood ratios and Bayes’ theorem to directly compute an individual woman’s risk of actually having a malignancy

297. Topic 0523 Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0620_131115.pdf
     March 13, 2013 - Topic 0523 Muscle Invasive Bladder Cancer NSD FINAL_SJ Muscle Invasive … Bladder Cancer Nomination Summary Document … How do current treatments for non-metastatic muscle invasive bladder cancer (i.e. … of non-metastatic invasive bladder cancer? … How do tumor characteristics (i.e. stage, grade, multiplicity, size, molecular and genetic alterations

298. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
     April 09, 2020 - Implant deflation* o Implant malposition* o Need for explant surgery* o Capsular contracture* o New neoplasms … Implant deflation* o Implant malposition* o Need for explant surgery* o Capsular contracture* o New neoplasms … Implant deflation* o Implant malposition* o Need for explant surgery* o Capsular contracture* o New neoplasms … https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/breast-cancer-facts-and-figures … /cancer-facts-and-statistics/breast-cancer-facts-and-figures/breast-cancer-facts-and-figures-2019-2020

299. What is the comparative effectiveness of various local treatments for (1) unresectable liver metastases and (2) unresectable, localized hepatocellular carcinoma (HCC)? Does the comparative effectiveness vary when lesions are unresectable… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-various-local-treatments-for-1-unresectable-liver-metastases-and-2-unresectable-localized-hepatocellular-carcinoma-hcc-does-the-comparative-effectiveness-vary-when-lesions-are-unresec
     November 01, 2017 - Treatment as a bridge to liver transplantation or to downstage tumor prior to transplantation also has … However, the majority of hepatic tumors are unresectable at diagnosis.) … This clinical scenario occurs frequently in patients with colorectal cancer. … It may also occur with other common tumors such as breast cancer. … Patients with unresectable tumors due to anatomic reasons (e.g. location of the tumor) may have different

300. Topic 0414 Imaging techniques and metastatic breast cancer tx NSD FINAL (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0495_05-24-2013.pdf
     January 01, 2013 - Topic 0414 Imaging techniques and metastatic breast cancer tx NSD FINAL … effectiveness of imaging techniques to Summary: assess response to treatment in metastatic breast cancer … The nominator is uncertain whether a specific imaging technique is best for the metastatic breast cancer … , PET/CT and FDG-PET Comparator(s): Those listed above (i.e., compared to each other) Outcome(s): Tumor … )  Metastatic or advanced breast cancer, defined as stage IV cancer, involves the spread of cancer