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1. Executive summary_Evaluation of Dietary Protein and Amino Acid Requirements: A Systematic Review (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
   November 01, 2024 - When more than two studies were available, different designs and/or methods to calculate the estimate … requirements for protein and indispensable amino acids varied both by population and by method used to calculate … two studies were available for protein or amino acids, they used different designs and/or methods to calculate … One strength is that we captured a wide array of methodologies used to calculate protein and amino

2. Slide 1
   effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
   January 01, 2013 - the level for the confidence interval Specify the statistical software and command or the formula to calculate … the level for the confidence interval; specify the statistical software and command or the formula to calculate … Calculate the study size, assuming the value represents the true treatment effect. … The tyranny of power: is there a better way to calculate sample size? BMJ 2009 Oct 6;339:b3985. … of 2) Guidance Key Considerations Specify the statistical software and command or the formula to calculate

3. Research White Paper: Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
   November 01, 2020 - project for institutional review board review Results: The process of preparing each registry to calculate … Initial results indicate that it is feasible to calculate the measures within the two patient registries … the necessary data, configure the PRO tool to capture the PHQ-9 at the appropriate intervals, and calculate … 8 Key Findings The primary objective of this project is to understand whether it is feasible to calculate … The process of preparing each registry to calculate the harmonized measures produced three major findings

4. Layout 1 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
   December 01, 2009 - A negative likelihood ratio can be used to calculate an individual woman’s risk of having a malignancy … MRI Any Insufficient Not possible to calculate Freehand Automated gun Insufficient Not possible to … calculate Type of guidance Method of biopsy Level of evidence ADH underestimation rate (95% CI) Any … MRI Any Insufficient Not possible to calculate Freehand Automated gun Insufficient Not possible to … calculate 12 Table E.

5. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
   September 21, 2012 - rate in the control group is combined with the specified treatment effect of interest, then one can calculate … noninferiority, inferiority. o Specify the statistical software and command, or the formula to calculate … The tyranny of power: Is there a better way to calculate sample size? BMJ. 2009;339:b3985. 6.

6. Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
   February 01, 2018 - Control Group Control n Study X 5 25 6 25 Study Y 23 194 21 189 • Ideally, the data necessary to calculate … ► Wald method3 is most common to calculate NNT confidence intervals, but the Wilson method is preferred … • Several methods exist to calculate SMD, including Cohen’s d and Hedges’ g.

7. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
   March 01, 2011 - There are several ways to calculate mean difference for continuous outcomes measured at both baseline … Use the followup score only to calculate a mean difference between intervention groups. 2 … If the study reported neither the mean difference nor enough data to calculate the mean difference … Then formula (3) can be used to calculate SE. … How to select, calculate, and interpret effect sizes. J Pediatr Psychol. 2009 Oct;34(9):917-28.

8. Appendixes A-D: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendices.pdf
   January 01, 2025 - 4,102) High (Serious concerns for bias) Direct Unknown (single study) Imprecise (unable to calculate … HCTZ and reported no dose association; thus, for this analysis, we combined these dosage groups to calculate … similar compared with placebo; thus, for this pooled analysis, we combined these dosage groups to calculate … pH) High (serious concerns for bias) Direct Unknown (single study) Imprecise (unable to calculate … 1,478) High (serious concerns for bias) Direct Unknown (single study) Imprecise (unable to calculate

9. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression: Final Report (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/outcome-research-white-paper.pdf
   June 01, 2022 - To calculate and display the measures in the health system setting, a Substitutable Medical Apps, Reusable … This project demonstrated that it is feasible to calculate the harmonized outcome measures for depression … To calculate the measures within these two patient registries, we used the standardized definitions … This approach was used to calculate the measure in the patient registries’ dashboards for this pilot … The objectives of this task were to design and develop a SMART on FHIR app to calculate and display

10. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - This allows the use of 2-by-2 tabulation to calculate true-positive, false-positive, true-negatives, … It is better to back calculate these values over a range of plausible prevalence values. … The fitted bivariate model can help calculate a whole range of hierarchical summary lines. … term=9419705 Methods Commonly Used To Calculate a Summary Line Preferred Methods for Obtaining … Calculate over a range of prevalence values using the summary sensitivity and specificity values.

11. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - This allows the use of 2-by-2 tabulation to calculate true-positive, false-positive, true-negatives, … It is better to back calculate these values over a range of plausible prevalence values. … The fitted bivariate model can help calculate a whole range of hierarchical summary lines. … term=9419705 Methods Commonly Used To Calculate a Summary Line Preferred Methods for Obtaining … Calculate over a range of prevalence values using the summary sensitivity and specificity values.

12. Zikmund (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/zikmund.pdf
    May 29, 2025 - Public Health, Ann Arbor, MI Slide  2: Imagine  Robert • Goes to an online risk calculator: o “Calculate

13. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
    February 01, 2006 - test in women without cancer; based on the risk of having the disease prior to the test, it is used to calculate

14. Kidney-Stones-Draft-Appendi-C (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
    January 01, 2024 - the precise N randomized and the precise N analyzed; Assuming that the N randomized is 124, we can calculate

15. Minimal Modeling Approaches to Value of Information Analysis for Health Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
    June 01, 2011 - These approaches require no modeling to calculate the individual level of value of information, and … To calculate net benefit, we accounted for both uncertainty in time to symptom resolution and willingness … metastatic pancreatic cancer 30 Conclusions While the use of decision-analytic models to calculate … To simplify such calculations for others, we have written a Stata command—evpi—that can be used to calculate … Second, the absence of a decision model makes it impossible to calculate the expected value of perfect

16. Test-Performance-Metrics Appendixes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/test-performance-metrics_appendixes.pdf
    January 01, 2005 - As we will discuss below, one way to summarize diagnostic accuracy data is to calculate a summary ROC

17. Cer-265-Radiation-Bone-Disease-Addendum-App (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    May 29, 2025 - treatment-related AE, % (n/N NR) 1.0% (2/209) vs. 0.8% (1/130) AEs by type, number of patients with an AE (cannot calculate

18. Disposition of Comments for CER 225: Substance Abuse Disorders in Adolescents (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-comments.pdf
    May 21, 2020 - Given our focus on consensus, we did not calculate inter-rater agreement.

19. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - For categorical variables we will abstract the number of events among treatment groups to calculate … Means and standard deviations of continuous variables will be abstracted to calculate mean differences … analysis set, we will abstract the number randomized to each treatment group as the denominator to calculate … Using Meta-Analyst 52 and STATA ®53 software at a 95 percent CI, we will calculate the relative … risk differences (ARD) in rates of outcome events in the active and control groups. 53, 59 We will calculate

20. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
    July 01, 2012 - and reference) agree or disagree (i.e., treat them as two alternative measurement methods); (c) to calculate … Instead of calculating sensitivity and specificity one would calculate statistics on test concordance … Work within the classical paradigm, and calculate “naïve estimates” of the index test’s sensitivity … disagree on the exact measurement among people who have larger measurements on average: One method may calculate … Calculate naïve estimates of the index test’s sensitivity and specificity from each study, but qualify