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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan37/vitamin-d-deficiency-screening
    March 24, 2014 - is the effect of vitamin D (with or without calcium) on intermediate outcomes (e.g., blood pressure, bone
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan37/vitamin-d-deficiency-screening-november-2014
    March 24, 2014 - is the effect of vitamin D (with or without calcium) on intermediate outcomes (e.g., blood pressure, bone
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary36/menopausal-hormone-therapy-preventive-medication-2012
    May 29, 2012 - This review includes health outcomes (such as fractures) rather than intermediate outcomes (such as bone … trial 58 compared an ultra-low dose of transdermal estradiol (0.014 mg/d) with placebo to evaluate bone … history of falls, personal or family history of fracture, calcium intake, previous hormone therapy, bone … Effects of ultralow-dose transdermal estradiol on bone mineral density: a randomized clinical trial. … placebo (208 vs. 209 participants) for 2 y Postmenopausal women without hysterectomies who had normal bone
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3Kwu7j_WfCFQSnSzqrDWwt
    June 20, 2019 - Bone. 2003;33(4):522-532. doi:10.1016/S8756-3282(03) 00241-2 68. … J Bone Miner Res. 2004;19(8): 1270-1275. doi:10.1359/JBMR.040406 70. … J Bone Miner Res. 2005;20(9):1514- 1524. doi:10.1359/JBMR.050509 75. … J Bone Miner Res. 2008;23(1):112-120. doi:10.1359/jbmr.070904 78. … in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial [
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary7/thyroid-dysfunction-screening
    October 28, 2014 - increased risk for all-cause and coronary heart disease mortality, atrial fibrillation, 9 and decreased bone … cognitive function; and harms, including those related to overreplacement (such as negative effects on bone … Intermediate outcomes were effects on lipid levels, blood pressure, weight change, and bone mineral density … Trials found no clear benefits of treatment of subclinical hypothyroidism on blood pressure, bone mineral … Favorable clinical heart and bone effects of anti-thyroid drug therapy in endogenous subclinical hyperthyroidism
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/G7CCbu64mf-nCynBkHbFLA
    July 01, 2012 - This review includes health outcomes (such as fractures) rather than intermediate outcomes (such as bone … trial (58) compared an ultra-low dose of transdermal estradiol (0.014 mg/d) with placebo to evaluate bone … his- tory of falls, personal or family history of fracture, calcium intake, previous hormone therapy, bone … Effects of ultralow-dose transdermal estradiol on bone mineral density: a randomized clinical trial. … placebo (208 vs. 209 participants) for 2 y Postmenopausal women without hysterectomies who had normal bone
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
    June 11, 2019 - associated with significant adverse events in adolescents but may be associated with slightly less bone … differences between PrEP and placebo. 44 , 46-50 Tenofovir disoproxil fumarate exposure is associated with boneBone mineral density in HIV-negative men participating in a tenofovir pre-exposure prophylaxis randomized … Effects of emtricitabine/tenofovir on bone mineral density in HIV-negative persons in a randomized, double-blind … Bone mineral density changes among HIV-uninfected young adults in a randomised trial of pre-exposure
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZyMe6J3wKnVkNuFP2p3W_5
    December 15, 2006 - Most lead is stored in bone. … High bone lead levels can be present with normal blood lead levels, so that blood lead levels often
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/6Y7RjECz_KLeGpJ4qQxmBC
    January 01, 2015 - risk for all- cause and coronary heart disease mortality, atrial fibril- lation (9), and decreased bone … cognitive func- tion; and harms, including those related to overre- placement (such as negative effects on bone … Intermediate outcomes were effects on lipid levels, blood pressure, weight change, and bone mineral density … Trials found no clear benefits of treatment of subclinical hypothyroidism on blood pressure, bone mineral … Favorable clinical heart and bone effects of anti-thyroid drug therapy in endogenous subclinical hyperthyroidism
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/v1-breast-cancer-medications-for-risk-reduction--s
    May 06, 2002 - Both the BCPT and MORE trials also examined the impact of these drugs on bone fractures. … Bone mass and breast cancer risk in older women: differences by stage at diagnosis. … Bone mass and the risk of breast cancer among postmenopausal women. … than breast cancer, women with particularly increased (or decreased) risk of thromboembolic events, bone … Possible benefits from tamoxifen or raloxifene chemoprevention include reduced risk of heart disease and bone
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-hnLT26c2NHs6thK9yznPF
    July 01, 2002 - Both the BCPT and MORE trials also examined the impact of these drugs on bone fractures. … Bone mass and breast cancer risk in older women: differences by stage at diagnosis. … Bone mass and the risk of breast cancer among postmenopausal women. … than breast cancer, women with particularly increased (or decreased) risk of thromboembolic events, bone … Possible benefits from tamoxifen or raloxifene chemoprevention include reduced risk of heart disease and bone
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction-2002
    May 06, 2002 - Both the BCPT and MORE trials also examined the impact of these drugs on bone fractures. … Bone mass and breast cancer risk in older women: differences by stage at diagnosis. … Bone mass and the risk of breast cancer among postmenopausal women. … than breast cancer, women with particularly increased (or decreased) risk of thromboembolic events, bone … Possible benefits from tamoxifen or raloxifene chemoprevention include reduced risk of heart disease and bone
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/xBhJwGtUHqmEvPg_gKk4nw
    January 01, 2001 - , quality of life, functional status, or morbidity KQ 5: Dental fluorosis, tooth staining, bone
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHT3WGUaG2wTz2pF_ke7bn
    January 14, 2025 - Abbreviations: BMD=bone mineral density; DXA=dual-energy X-ray absorptiometry; FDA=U.S.
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lead-levels-in-childhood-and-pregnancy-screening-2006
    December 15, 2006 - Most lead is stored in bone. … High bone lead levels can be present with normal blood lead levels, so that blood lead levels often
  16. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-adults-interventions
    March 31, 2016 - medical treatment, inducement of eating disorder, nausea or other gastrointestinal effects, reduced bone
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/poDYcagnw7SqKNNbrFt_CV
    June 11, 2019 - associated with significant adverse events in adolescents but may be associated with slightly less bone … ferences between PrEP and placebo.44,46-50 Tenofovir disoproxil fumarate exposure is associated with boneBone mineral density in HIV-negative men participating in a tenofovir pre-exposure prophylaxis randomized … Effects of emtricitabine/tenofovir on bone mineral density in HIV-negative persons in a randomized, double-blind … Bone mineral density changes among HIV-uninfected young adults in a randomised trial of pre-exposure
  18. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/syphilis-infection-pregnant-persons
    November 19, 2024 - birth weight, stillbirth, neonatal death, and significant abnormalities in the infant such as deformed bones
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-in-pregnancy-screening-2009
    May 15, 2009 - Importance Untreated syphilis during pregnancy is associated with stillbirth, neonatal death, bone
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/celiac-disease-screening
    March 28, 2017 - Serologic testing for celiac disease should be considered for persons with any of the following: metabolic bone … disorder (reduced bone mineral density or osteomalacia), unexplained neurologic symptoms (particularly

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