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41. Exhibit 2.4 Average Length of Stay and Average Charges
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_4.jsp
    January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones … (acute anemia from bleeding) 12.6 0.568 3.6 0.203794 14,500 572 212 Other bone … or graft 615.9 22.043 6.0 0.071983 41,100 1,170 206 Osteoporosis (loss of bone … without specification of site) 5.6 0.266 7.2 0.264813 29,100 1,511 21 Cancer of bone … 0.106296 46,100 1,308 201 Infective arthritis and osteomyelitis (infective arthritis and bone

42. Neds 2016 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2016_ED_MaskedStats.PDF
    January 01, 2016 - cardiovascular procedures 622 0.00 63: Other non-OR therapeutic cardiovascular procedures 18,798 0.07 64: Bone … marrow transplant 12 0.00 65: Bone marrow biopsy 133 0.00 66: Procedures on spleen <= 10 *.** 67: … obstetric laceration 22 0.00 141: Other therapeutic obstetrical procedures 48 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,918 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 499,700 1.76 207: Radioisotope bone

43. HCUP Statistical Brief #34: Hospital Stays Involving Musculoskeletal Procedures, 1997–2005 (pdf file)
    hcup-us.ahrq.gov/reports/statbriefs/sb34.pdf
    July 01, 2007 - Introduction The musculoskeletal system is comprised of the muscles, bones, and cartilage that are … The Journal of Bone and Joint Surgery, 87(7):1487-97. 4Kurtz, S., Ong, K., Lau, E., Mowat, F., and Halpern … The Journal of Bone and Joint Surgery, 89(4):780-5. 2 http://www.ahrq.gov/data/hcup/factbk9/ http … categories (italicized procedures are discussed in more depth in this brief): – 142: Partial excision of bone … therapeutic procedures on muscles and tendons – 161: Other operating room therapeutic procedures on bone

44. Neds 2011V2 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2011v2_MaskedStats_ED.PDF
    November 03, 2014 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 41 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 2,027 0.01 161: Other OR therapeutic procedures on bone … November 3, 2014 10 Frequency Distribution for CPTCCS1 CPTCCS1 Frequency Percent 207: Radioisotope bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 59 0.00 66: Procedures on spleen <= 10 *.** … 206: Microscopic examination (bacterial smear; culture; toxicology) 45,653 0.19 207: Radioisotope bone

45. Neds 2012 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2012_MaskedStats_ED.PDF
    January 01, 2012 - 12 Tuesday, November 18, 2014 6 Frequency Distribution for CPTCCS1 CPTCCS1 Frequency Percent 65: Bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 391,055 1.47 207: Radioisotope bone … Tuesday, November 18, 2014 17 Frequency Distribution for PRCCS_ED1 PRCCS_ED1 Frequency Percent 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 72 0.00 66: Procedures on spleen <= 10 *.** 67 … 0.00 206: Microscopic examination (bacterial smear; culture; toxicology) 709 0.00 207: Radioisotope bone

46. Neds 2011 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2011_MaskedStats_ED.PDF
    January 01, 2011 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 45 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 2,331 0.01 161: Other OR therapeutic procedures on bone … December 5, 2013 10 Frequency Distribution for CPTCCS1 CPTCCS1 Frequency Percent 207: Radioisotope bone … Thursday, December 5, 2013 17 Frequency Distribution for PRCCS_ED1 PRCCS_ED1 Frequency Percent 65: Bone … 206: Microscopic examination (bacterial smear; culture; toxicology) 60,222 0.24 207: Radioisotope bone

47. Ccscategorynames Fulllabels (pdf file)
    hcup-us.ahrq.gov/toolssoftware/ccs/CCSCategoryNames_FullLabels.pdf
    October 07, 2016 - peritoneum 19 Cancer of bronchus; lung 20 Cancer; other respiratory and intrathoracic 21 Cancer of bone … Other diagnostic cardiovascular procedures 63 Other non-OR therapeutic cardiovascular procedures 64 Bone … marrow transplant 65 Bone marrow biopsy 66 Procedures on spleen 67 Other therapeutic procedures; hemic … breast 175 Other OR therapeutic procedures on skin and breast 176 Organ transplantation (other than bone … 206 Microscopic examination (bacterial smear; culture; toxicology) 207 Nuclear medicine imaging of bone

48. Neds 2013 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2013_MaskedStats_ED.PDF
    January 01, 2013 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 49 0.00 66: Procedures on spleen <= 10 *.** … laceration <= 10 *.** 141: Other therapeutic obstetrical procedures 38 0.00 142: Partial excision bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 321,700 1.27 207: Radioisotope bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 65 0.00 66: Procedures on spleen <= 10 *.** 67 … 0.00 206: Microscopic examination (bacterial smear; culture; toxicology) 334 0.00 207: Radioisotope bone

49. Neds 2010 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2010_MaskedStats_ED.PDF
    January 01, 2010 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 33 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 1,891 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 238,669 0.99 207: Radioisotope bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 57 0.00 please refer to the section on Description … 206: Microscopic examination (bacterial smear; culture; toxicology) 19,787 0.08 207: Radioisotope bone

50. Statistical Brief #132
    hcup-us.ahrq.gov/reports/statbriefs/sb132.jsp
    May 01, 2012 - for leukemias (6,900 stays), cancer of the brain and nervous system (3,900 stays), and cancer of the bone … of brain and nervous system, 2000; number of stays, 4,200; 2009; number of stays, 3,900; Cancer of bone … Increases were more modest for cancer of the bone and connective tissue, non-Hodgkin's lymphoma, cancers … 23,100; Hodgkin's disease, 2000; number of stays, 25,300; 2009; number of stays, 28,400; Cancer of bone … stays with a secondary diagnosis of cancer were for leukemias, 21.0 percent were for cancer of the bone

51. Most Frequent Operating Room Procedures Performed in U.S. Hospitals, 2003–2012 (pdf file)
    hcup-us.ahrq.gov/reports/statbriefs/sb186-Operating-Room-Procedures-United-States-2012.pdf
    January 01, 2012 - fusion 450,900 143.6 6 Cholecystectomy and common duct exploration 406,300 129.4 7 Partial excision bone … 468,200 stays), hip replacement (468,000 stays), spinal fusion (450,900 stays), and partial excision bone … 223.0 4.9 3 Arthroplasty other than hip or knee 55,900 90,000 19.3 28.7 4.5 4 Partial excision bone … Arthroplasty, other than the hip or knee (4.5 percent average annual increase) • Partial excision bone … 290,600 1 Appendectomy 68,800 Debridement of wound, infection or burn –9.1 2 Partial excision bone

52. Cancer
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2006/2006_5_3a.jsp
    January 01, 2006 - unspecified nature or uncertain behavior 50 15% Cancer of thyroid 30 15% Cancer of bone

53. Neds 2020 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2020_ED_MaskedStats.PDF
    January 01, 2020 - cardiovascular procedures 666 0.00 63: Other non-OR therapeutic cardiovascular procedures 13,002 0.06 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 97 0.00 66: Procedures on spleen <= 10 *.** 67 … therapeutic obstetrical procedures including antepartum and postpartum care 200 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,448 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 426,244 1.82 207: Radioisotope bone

54. Facts and Figures Exhibit 2.1
    hcup-us.ahrq.gov/reports/factsandfigures/2007/exhibit2_1.jsp
    January 01, 2007 - (blood infection) 413 675 1.2 1.7 16 8 63 Disorders of intervertebral discs and bones

55. Neds 2018 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2018_ED_MaskedStats.PDF
    January 01, 2018 - cardiovascular procedures 1,255 0.00 63: Other non-OR therapeutic cardiovascular procedures 12,578 0.04 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 91 0.00 66: Procedures on spleen <= 10 *.** 67 … obstetric laceration 69 0.00 141: Other therapeutic obstetrical procedures 111 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,586 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 753,556 2.45 207: Radioisotope bone

56. Neds 2019 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2019_ED_MaskedStats.PDF
    January 01, 2019 - cardiovascular procedures 1,491 0.01 63: Other non-OR therapeutic cardiovascular procedures 11,778 0.04 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 91 0.00 66: Procedures on spleen <= 10 *.** 67 … therapeutic obstetrical procedures including antepartum and postpartum care 141 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,430 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 536,673 1.89 207: Radioisotope bone

57. Neds 2009 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2009_MaskedStats_ED.PDF
    January 01, 2009 - Saturday, September 10, 2011 6 Frequency Distribution for CPTCCS1 CPTCCS1 Frequency Percent 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 31 0.00 66: Procedures on spleen <= 10 *.** 67 … 206: Microscopic examination (bacterial smear, culture, toxicology) 242,334 0.99 207: Radioisotope bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 140 0.00 66: Procedures on spleen 36 0.00 67: … 206: Microscopic examination (bacterial smear; culture; toxicology) 25,078 0.10 207: Radioisotope bone

58. Neds 2008 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2008_MaskedStats_ED.PDF
    January 01, 2008 - 10:09 Tuesday, August 10, 2010 6 Frequency Distribution for CPTCCS1 CPTCCS1 Frequency Percent 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 33 0.00 66: Procedures on spleen <= 10 *.** 67 … 206: Microscopic examination (bacterial smear, culture, toxicology) 218,084 0.91 207: Radioisotope bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 68 0.00 66: Procedures on spleen 19 0.00 67: … 206: Microscopic examination (bacterial smear; culture; toxicology) 21,850 0.09 207: Radioisotope bone

59. Most Frequent Operating Room Procedures Performed in U.S. Hospitals, 2003-2012 #186
    hcup-us.ahrq.gov/reports/statbriefs/sb186-Operating-Room-Procedures-United-States-2012.jsp
    December 01, 2014 - 6 Cholecystectomy and common duct exploration 406,300 129.4 7 Partial excision bone … 468,200 stays), hip replacement (468,000 stays), spinal fusion (450,900 stays), and partial excision bone … Arthroplasty other than hip or knee 55,900 90,000 19.3 28.7 4.5 4 Partial excision bone … Arthroplasty, other than the hip or knee (4.5 percent average annual increase) Partial excision bone … Appendectomy 68,800 Debridement of wound, infection or burn -9.1 2 Partial excision bone

60. Neds 2014 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2014_MaskedStats_ED.PDF
    January 01, 2014 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 63 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 5,306 0.02 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 474,989 1.78 207: Radioisotope bone … PRCCS_ED1 Frequency Percent 63: Other non-OR therapeutic cardiovascular procedures 597 0.00 65: Bone … Other therapeutic procedures on muscles and tendons 2,149 0.01 161: Other OR therapeutic procedures on bone