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1. Radiation Therapy for Bone Metastases (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
   August 10, 2022 - location, whether they are osteolytic, osteoblastic, or mixed), the mechanical stability of the affected bones … Palliation of bone metastases-exploring options beyond radiotherapy. … The role of radiation therapy in bone metastases management. … A Further Analysis of the Dutch Bone Metastasis Study. … KQ1: ("bone metastases"[Title/Abstract] OR "bone neoplasms/radiotherapy"[MeSH Terms]) AND ("external

2. Osteoporosis-Bone-Fracture Executive (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
   March 01, 2012 - mass and microarchitectural deterioration of bone tissue, with consequent increases in bone fragility … maintenance of bone health. … When serum calcium levels are inadequate, bone tissue is resorbed from the skeleton to maintain serum … strength include bone mineral density and bone quality; some aspects of bone quality that might affect … J Bone Miner Res. 2003;18(6):1125-8. 13.

3. Bone Diseases | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/bone-diseases
   November 15, 2011 - Archived November 15, 2011 Treatment To Prevent Fractures in Men and Women With Low Bone … 2012 Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone … 2010 Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone

4. Bone Density | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/bone-density/

5. Bone Infections | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/bone-infections

6. Localized Prostate Cancer | Effective Health Care
   effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/20.html
   June 08, 2018 - low sex drive), impotence or erectile dysfunction, diarrhea, osteoporosis (a disease that makes your bones … thin and weak), muscle and bone loss, broken bones, and "androgen deprivation syndrome," which includes

7. Bone Marrow Diseases | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/bone-marrow-diseases

8. Bone Cancer | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/bone-cancer

9. Osteoporosis-Vibration-Therapy Research-Protocol (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
   January 01, 2020 - mass and deterioration of bone tissue.1 Osteoporosis is a significant public health problem that … tissue, directly activating mechanosensors in bone cells.33 Animal studies demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone http://www.effectivehealthcare.ahrq.gov … Good, good, good... good vibrations: the best option for better bones? … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

10. Bone Marrow Transplantation | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/bone-marrow-transplantation

11. Technical Brief: Whole Body Vibration Therapy for Osteoporosis | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/osteoporosis-vibration-therapy/research-protocol
    December 09, 2010 - mass and deterioration of bone tissue. 1 Osteoporosis is a significant public health problem that leads … tissue, directly activating mechanosensors in bone cells.33 Animal studies demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone density. 24,34-36 … Vibration exercise makes your muscles and bones stronger: fact or fiction? … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

12. Topic Brief: Radiation Therapy for Bone Metastases (pdf file)
    effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-radiation-therapy-bone-metastases.pdf
    August 01, 2022 - Topic Brief: Radiation Therapy for Bone Metastases 1 Topic Brief: Radiation Therapy for Bone … (bone metastasis). … A 2020 population-based study of patients with bone metastases found that the incidence of bone metastases … neoplasms/sc (19257) 2 bone metastas*.ti,ab,kf. (17492) 3 or/1-2 (27965) 4 bone neoplasms/rt or ( … In a 2020 population- based study of patients with bone metastases, the incidence of bone metastasis

13. Whole-Body Vibration Therapy for Osteoporosis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
    January 01, 2020 - tissue. … density and deterioration of bone tissue.1 The clinical ranges for osteoporosis, osteopenia, and normal … tissue, directly activating mechanosensors in bone cells.40 Animal studies have demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone density.26,41-43 … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

14. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/osteoporosis-bone-fracture/research-protocol
    May 14, 2010 - mass and microarchitectural deterioration of bone tissue, with consequent increases in bone fragility … Osteoporosis is diagnosed by assessing bone mineral density (BMD). … Low bone mass or density is defined as a T-score between -2.5 and -1. … America’s bone health: The state of osteoporosis and low bone mass in our nation. … J Bone Miner Res. 2007 Mar;22(3):465-75. National Osteoporosis Foundation.

15. Cer-265-Radiation-Bone-Disease-Addendum-App (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    October 12, 2023 - controlled trial evaluating external beam radiation therapy for the palliative treatment of metastatic bone … Analyzed at Final Follow-Up, Attrition Intervention, Comparator Prior and Concurrent Treatments Site of Bone … Metastases Characteristics of Bone Metastases Primary Tumor Histology Age, Mean Overall Population Sex … Asian: 4.4% Other: 1.2% Not reported/ unknown: 2.9% NR Comorbidities: NR Duration of pain: NR Non-bone

16. Rt-Bone-Metatases-Qa-Tables-Appendix-F (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rt-bone-metatases-qa-tables-appendix-F.xlsx
    January 01, 2019 - controlled trials evaluating external beam radiation therapy for the palliative treatment of metastatic bone … No Unclear Unclear Unclear Yes Fair Badzio, 2003 Yes Yes Yes No No No Yes Yes Yes Unclear Yes Fair Bone … (Sprave, 2018 above) Unclear Unclear No Unclear No No Yes No Yes No Yes Fair Steenland, 1999 Dutch Bone … (subsequent publication) NA NA Yes Unclear No No Yes No Yes NA Yes Fair van der linden, 2004 Dutch Bone … intervention evaluating external beam radiation therapy for the palliative treatment of metastatic bone

17. Cer-265-Radiation-Bone-Disease-App-F (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
    January 01, 2019 - controlled trials evaluating external beam radiation therapy for the palliative treatment of metastatic bone … No Unclear Unclear Unclear Yes Fair Badzio, 2003 Yes Yes Yes No No No Yes Yes Yes Unclear Yes Fair Bone … (Sprave, 2018 above) Unclear Unclear No Unclear No No Yes No Yes No Yes Fair Steenland, 1999 Dutch Bone … (subsequent publication) NA NA Yes Unclear No No Yes No Yes NA Yes Fair van der linden, 2004 Dutch Bone … interventions evaluating external beam radiation therapy for the palliative treatment of metastatic bone

18. The Effect of Protein Intake on Health (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
    November 29, 2023 - growth factor 1(IGF 1), a growth hormone that promotes normal growth in bones and tissues,6 and 2) … bone mineral density, bone mineral content Inclusion criteria: Bone outcomes including but not … ti,ab. 351405 2 "Bone and Bones"/ or Bone Density/ or bone diseases/ or bone diseases, metabolic/ or … bone demineralization, pathologic/ or bone resorption/ or Fractures, Bone/ or (bone disease? … or bone densit* or bone demineralization or bone health or bone mass or bone resorption or fracture*

19. The Effect of Protein Intake on Health (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol.pdf
    May 01, 2023 - growth factor 1(IGF 1), a growth hormone that promotes normal growth in bones and tissues,6 and 2) … intestinal calcium absorption, which promotes bone mineralization, a process by which bone matrix … ti,ab. 351405 2 "Bone and Bones"/ or Bone Density/ or bone diseases/ or bone diseases, metabolic/ or … bone demineralization, pathologic/ or bone resorption/ or Fractures, Bone/ or (bone disease? … or bone densit* or bone demineralization or bone health or bone mass or bone resorption or fracture*

20. Radiation Therapy for Bone Metastases | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/radiation-therapy-bone-metastases
    July 17, 2020 - The use of radiation therapy in the management of cancer that has metastasized to the bone, referred … to as bone metastases, has shown significant variation in care across different clinical settings, and … For these reasons and the high incidence and clinical need for palliative radiation for bone metastases … KQ 5: In patients with bone metastases receiving palliative radiation therapy, how do the different … These patients frequently experience morbidity from bone metastases, including pain, bone fracture, reduced