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41. Neds 2019 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2019_ED_MaskedStats.PDF
    January 01, 2019 - cardiovascular procedures 1,491 0.01 63: Other non-OR therapeutic cardiovascular procedures 11,778 0.04 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 91 0.00 66: Procedures on spleen <= 10 *.** 67 … therapeutic obstetrical procedures including antepartum and postpartum care 141 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,430 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 536,673 1.89 207: Radioisotope bone

42. Exhibit 2.3 Most Frequent Diagnoses by Sex
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_3.jsp
    January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones

43. Neds 2014 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2014_MaskedStats_ED.PDF
    January 01, 2014 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 63 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 5,306 0.02 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 474,989 1.78 207: Radioisotope bone … PRCCS_ED1 Frequency Percent 63: Other non-OR therapeutic cardiovascular procedures 597 0.00 65: Bone … Other therapeutic procedures on muscles and tendons 2,149 0.01 161: Other OR therapeutic procedures on bone

44. PC-ICD10PCSChgLg-v20221-v20222 (xls file)
    hcup-us.ahrq.gov/toolssoftware/procedureicd10/PClassR-ChangeLg-v20221-v20222.xlsx
    March 01, 2022 - , Open Approach 4 Major Therapeutic 2 Minor Therapeutic 0N9B00Z Drainage of Nasal Bone with Drainage … Device, Open Approach 4 Major Therapeutic 2 Minor Therapeutic 0N9B0ZX Drainage of Nasal Bone, Open … , Open Approach 4 Major Therapeutic 2 Minor Therapeutic 0NHB0MZ Insertion of Bone Growth Stimulator … into Nasal Bone, Open Approach 4 Major Therapeutic 2 Minor Therapeutic 0NNB0ZZ Release Nasal Bone, Open … Therapeutic 0NWB0MZ Revision of Bone Growth Stimulator in Nasal Bone, Open Approach 4 Major Therapeutic

45. Statistical Brief #34
    hcup-us.ahrq.gov/reports/statbriefs/sb34.jsp
    July 01, 2007 - Introduction The musculoskeletal system is comprised of the muscles, bones, and cartilage that are … categories (italicized procedures are discussed in more depth in this brief): – 142: Partial excision of bone … therapeutic procedures on muscles and tendons – 161: Other operating room therapeutic procedures on bone … The Journal of Bone and Joint Surgery , 87(7):1487-97. 4 Kurtz, S., Ong, K., Lau, E., Mowat, F., and … The Journal of Bone and Joint Surgery , 89(4):780-5. 5 HCUP Cost-to-Charge Ratio Files (CCR).

46. Most Frequent Operating Room Procedures Performed in U.S. Hospitals, 2003-2012 #186
    hcup-us.ahrq.gov/reports/statbriefs/sb186-Operating-Room-Procedures-United-States-2012.jsp
    December 01, 2014 - 6 Cholecystectomy and common duct exploration 406,300 129.4 7 Partial excision bone … 468,200 stays), hip replacement (468,000 stays), spinal fusion (450,900 stays), and partial excision bone … Arthroplasty other than hip or knee 55,900 90,000 19.3 28.7 4.5 4 Partial excision bone … Arthroplasty, other than the hip or knee (4.5 percent average annual increase) Partial excision bone … Appendectomy 68,800 Debridement of wound, infection or burn -9.1 2 Partial excision bone

47. Statistics From the HCUP-3 Nationwide Inpatient Sample for 1993: Principal Procedures
    hcup-us.ahrq.gov/reports/natstats/93pcchp.htm
    November 01, 1998 - non-OR therapeutic 35,285 0.10 10.30 20,961 cardiovascular procedures 64 Bone … marrow transplant 9,291 0.03 38.13 170,086 65 Bone marrow biopsy 72,676 … 0.03 1.95 3,433 obstetrical procedures 142 Partial excision bone … tendons 161 Other OR therapeutic 45,230 0.13 5.20 12,928 procedures on bone … 0.04 5.74 4,422 (bacterial smear, culture, toxicology) 207 Radioisotope bone

48. HCUP-3 Nationwide Inpatient Sample for 1994: Principal Procedures
    hcup-us.ahrq.gov/reports/natstats/94pcchpr.htm
    November 01, 1998 - non-OR therapeutic 37,443 0.11 9.76 21,823 cardiovascular procedures 64 Bone … marrow transplant 7,310 0.02 34.93 168,513 65 Bone marrow biopsy 69,381 … 9,939 0.03 1.99 3,818 obstetrical procedures 142 Partial excision bone … tendons 161 Other OR therapeutic 41,442 0.12 4.92 13,538 procedures on bone … 0.04 4.95 4,233 (bacterial smear, culture, toxicology) 207 Radioisotope bone

49. Neds 2017 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2017_ED_MaskedStats.PDF
    January 01, 2017 - cardiovascular procedures 841 0.00 63: Other non-OR therapeutic cardiovascular procedures 16,685 0.06 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 83 0.00 66: Procedures on spleen <= 10 *.** 67 … obstetric laceration 20 0.00 141: Other therapeutic obstetrical procedures 93 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 2,649 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 495,311 1.72 207: Radioisotope bone

50. Neds 2015Q4 Ed Maskedstats (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2015Q4_ED_MaskedStats.PDF
    December 14, 2017 - cardiovascular procedures 117 0.00 63: Other non-OR therapeutic cardiovascular procedures 4,143 0.06 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 21 0.00 67: Other therapeutic procedures, hemic … laceration <= 10 *.** 141: Other therapeutic obstetrical procedures 20 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 567 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 111,977 1.71 207: Radioisotope bone

51. Statistical Brief #132: Pediatric Cancer Hospitalizations, 2009 (pdf file)
    hcup-us.ahrq.gov/reports/statbriefs/sb132.pdf
    March 01, 2012 - leukemias (6,900 stays), cancer of the brain and nervous system (3,900 stays), and cancer of the bone … most common childhood cancers:4 leukemias, cancer of the brain and nervous system, and cancer of the bone … Increases were more modest for cancer of the bone and connective tissue, non- Hodgkin’s lymphoma, cancers … stays with a secondary diagnosis of cancer were for leukemias, 21.0 percent were for cancer of the bone … pediatrics stays with a secondary diagnosis of cancer 73,300 100.0% Leukemias 26,400 36.0% Cancer of bone

52. Exhibit 2.4 Average Length of Stay and Average Charges
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_4.jsp
    January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones … (acute anemia from bleeding) 12.6 0.568 3.6 0.203794 14,500 572 212 Other bone … or graft 615.9 22.043 6.0 0.071983 41,100 1,170 206 Osteoporosis (loss of bone … without specification of site) 5.6 0.266 7.2 0.264813 29,100 1,511 21 Cancer of bone … 0.106296 46,100 1,308 201 Infective arthritis and osteomyelitis (infective arthritis and bone

53. Maskedstats Nis 2022 Severity (pdf file)
    hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2022_Severity.PDF
    January 01, 2022 - >96 hours without extensive procedure 7,719 0.12% 6: Pancreas transplant 165 0.00% 7: Allogeneic bone … marrow transplant 1,745 0.03% 8: Autologous bone marrow transplant or T-cell immunotherapy 2,239 0.03% … procedures 1,785 0.03% 82: Eye infections and other eye disorders 7,065 0.11% 89: Major cranial or facial bone … procedures 3,282 0.05% 91: Other major head and neck procedures 2,806 0.04% 92: Facial bone procedures … except major cranial or facial bone procedures 3,583 0.05% 95: Cleft lip and palate repair 415 0.01%

54. Maskedstats Nis 2021 Severity (pdf file)
    hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2021_Severity.PDF
    January 01, 2021 - >96 hours without extensive procedure 10,881 0.16% 6: Pancreas transplant 165 0.00% 7: Allogeneic bone … marrow transplant 1,721 0.03% 8: Autologous bone marrow transplant or T-cell immunotherapy 2,976 0.04% … procedures 1,720 0.03% 82: Eye infections and other eye disorders 6,251 0.09% 89: Major cranial or facial bone … procedures 3,333 0.05% 91: Other major head and neck procedures 2,714 0.04% 92: Facial bone procedures … except major cranial or facial bone procedures 3,619 0.05% 95: Cleft lip and palate repair 450 0.01%

55. Maskedstats Nis 2020 Severity V2 (pdf file)
    hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2020_Severity_V2.PDF
    January 01, 2020 - >96 hours without extensive procedure 9,001 0.14% 6: Pancreas transplant 189 0.00% 7: Allogeneic bone … marrow transplant 1,671 0.03% 8: Autologous bone marrow transplant or T-cell immunotherapy 2,707 0.04% … procedures 1,621 0.03% 82: Eye infections and other eye disorders 5,282 0.08% 89: Major cranial or facial bone … procedures 3,295 0.05% 91: Other major head and neck procedures 2,529 0.04% 92: Facial bone procedures … except major cranial or facial bone procedures 3,467 0.05% 95: Cleft lip and palate repair 489 0.01%

56. Maskedstats Nrd 2018 Severity (pdf file)
    hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2018_Severity.PDF
    January 01, 2018 - MV 96+ hours w/o extensive procedure 17,564 0.10% 6: Pancreas transplant 515 0.00% 7: Allogeneic bone … marrow transplant 4,263 0.02% 8: Autologous bone marrow transplant 6,078 0.03% 9: Extracorporeal membrane … procedures 4,263 0.02% 82: Eye infections and other eye disorders 15,469 0.09% 89: Major cranial/facial bone … procedures 8,444 0.05% 91: Other major head & neck procedures 6,568 0.04% 92: Facial bone procedures … except major cranial/facial bone procedures 10,642 0.06% 95: Cleft lip & palate repair 633 0.00% 97

57. Neds 2007V2 Maskedstats Ed (pdf file)
    hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2007v2_MaskedStats_ED.PDF
    April 09, 2010 - :09 Friday, April 9, 2010 9 Frequency Distribution for PRCCS_ED1 PRCCS_ED1 Frequency Percent 64: Bone … marrow transplant <= 10 *.** 65: Bone marrow biopsy 224 0.00 66: Procedures on spleen 13 0.00 67: … obstetric laceration 23 0.00 141: Other therapeutic obstetrical procedures 141 0.00 142: Partial excision bone … Other therapeutic procedures on muscles and tendons 7,541 0.03 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear; culture; toxicology) 11,881 0.05 207: Radioisotope bone

58. Microsoft Word - Table1-FY2010-V3_5.doc (pdf file)
    hcup-us.ahrq.gov/toolssoftware/comorbidity/Table1-FY2010-V3_5.pdf
    September 01, 2009 - Secondary neuroendocrine tumor of liver Metastatic cancer *209.73 Secondary neuroendocrine tumor of bone

59. HCUP Statistical Brief #34: Hospital Stays Involving Musculoskeletal Procedures, 1997–2005 (pdf file)
    hcup-us.ahrq.gov/reports/statbriefs/sb34.pdf
    July 01, 2007 - Introduction The musculoskeletal system is comprised of the muscles, bones, and cartilage that are … The Journal of Bone and Joint Surgery, 87(7):1487-97. 4Kurtz, S., Ong, K., Lau, E., Mowat, F., and Halpern … The Journal of Bone and Joint Surgery, 89(4):780-5. 2 http://www.ahrq.gov/data/hcup/factbk9/ http … categories (italicized procedures are discussed in more depth in this brief): – 142: Partial excision of bone … therapeutic procedures on muscles and tendons – 161: Other operating room therapeutic procedures on bone

60. Maskedstats Nrd 2021 Severity (pdf file)
    hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2021_Severity.PDF
    January 01, 2021 - >96 hours without extensive procedure 30,487 0.18% 6: Pancreas transplant 462 0.00% 7: Allogeneic bone … marrow transplant 4,420 0.03% 8: Autologous bone marrow transplant or T-cell immunotherapy 7,682 0.05% … procedures 4,209 0.03% 82: Eye infections and other eye disorders 16,459 0.10% 89: Major cranial or facial bone … procedures 7,836 0.05% 91: Other major head and neck procedures 7,448 0.04% 92: Facial bone procedures … except major cranial or facial bone procedures 9,254 0.06% 95: Cleft lip and palate repair 593 0.00%