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101. Exhibit 2.2. Most Frequent Diagnoses by Age
     hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_2.jsp
     January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones

102. Icd-10 Pcs Trends 11022017 (pdf file)
     hcup-us.ahrq.gov/datainnovations/ICD-10_PCS_Trends_11022017.pdf
     November 02, 2017 - 1) Peripheral Nervous System (M) Bursae & Ligaments (2) Heart and Great Vessels (N) Head & Facial Bones … (3) Upper Arteries (P) Upper Bones (4) Lower Arteries (Q) Lower Bones (5) Upper Veins (R) Upper … Pancreas (L) Tendons (G) Endocrine System (M) Bursae & Ligaments (H) Skin & Breast (N) Head & Facial Bones … (J) Subcutaneous Tissue & Fascia (P) Upper Bones (K) Muscles (Z) Used as a placeholder if another … marrow transplant 2,223 2,422 2,442 9.0 0.8 65: Bone marrow biopsy 11,129 11,347 10,784 2.0 –5.0

103. Clinical Classifications for Health Policy Research: Hospital Inpatient Statistics, 1995
     hcup-us.ahrq.gov/reports/natstats/his95/table2c.htm
     February 11, 2011 - 5.21 $16,432 $7,305 $12,828 $20,134 6.0 1.2 45.4 58 14.1 Partial excision bone … $4,589 $7,083 $11,566 4.4 0.9 62.9 41 14.14 Other OR therapeutic procedures on bone … 0.29 $9,851 $4,598 $7,213 $11,716 6.2 2.1 41.4 62 16.24.1 Radioisotope bone

104. Hospital Inpatient Statistics, 1996
     hcup-us.ahrq.gov/reports/natstats/his96/table2c.htm
     January 01, 1996 - $7,819 $13,403 $20,529 5.5 1.1 44.7 59.1 14.1 Partial excision bone … $12,274 4.4 0.8 61.4 41.9 14.14 Other OR therapeutic procedures on bone … $4,742 $7,325 $11,929 5.9 1.8 41.0 62.3 16.24.1 Radioisotope bone

105. Appendix D (pdf file)
     hcup-us.ahrq.gov/reports/natstats/his95/appendd.pdf
     February 11, 2011 - cardiovascular procedures 63 - 8 Operations on the hemic and lymphatic system 64 65 66 67 - 8.1 Bone … marrow transplant 64 - 8.2 Bone marrow biopsy 65 - 8.3 Procedures on spleen 66 - 8.4 Other therapeutic … 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 - 14.1 Partial excision bone

106. Exhibit 2.1. Most Frequent Principal Diagnoses
     hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_1.jsp
     January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones

107. Section4 2 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2007/pdfs/section4_2.pdf
     January 01, 2007 - 9.5 5.8 47.0 Disorders of intervertebral discs and bones

108. Statistical Brief #24
     hcup-us.ahrq.gov/reports/statbriefs/sb24.jsp
     January 01, 2007 - (a hole between the two larger chambers of the heart), congenital anomalies of the skull and facial bones … 3.6 $12,500 $26,930,200 28.6% 27.4 0.0% Congenital anomalies of skull and facial bones … 11 Hypospadias and epispadias 18,100 12 Congenital anomalies of skull and facial bones

109. HCUP Statistical Brief #24: Hospitalizations for Birth Defects, 2004 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb24.pdf
     January 01, 2007 - a hole between the two larger chambers of the heart), congenital anomalies of the skull and facial bones … deformity 2,200 1.5% 3.6 $12,500 $26,930,200 28.6% 27.4 0.0% Congenital anomalies of skull and facial bones … epispadias 18,100 12 Congenital anomalies of skull and facial bones

110. Most Common Diagnoses and Procedures in U.S. Community Hospitals, 1996
     hcup-us.ahrq.gov/reports/natstats/commdx/table1c.htm
     February 11, 2011 - Other bone disease and musculoskeletal deformities [212] 18,053 6.19 0.05 … Other bone disease and musculoskeletal deformities [212] 5,037 1.76 0.01

111. Clinical Classifications for Health Policy Research: Hospital Inpatient Statistics, 1995
     hcup-us.ahrq.gov/reports/natstats/his95/appda.htm
     February 11, 2011 - cardiovascular procedures 8 Operations on the hemic and lymphatic system 64 65 66 67 - 8.1 Bone … marrow transplant 64 - 8.2 Bone marrow biopsy

112. Surgeries in Hospital-Owned Outpatient Facilities, 2012 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb188-Surgeries-Hospital-Outpatient-Facilities-2012.pdf
     January 01, 2012 - 202 323 110 176 38.5 Other excision of cervix and uterus 2.2 201 33 110 18 85.9 Partial excision bone … 2.0 190 245 104 134 43.7 Other OR therapeutic procedures on bone 1.9 180 96 98 52 65.3 Transurethral … in the outpatient setting: excision of semilunar cartilage of knee (3.6 percent), partial excision bone … (2.0 percent), other operating room (OR) therapeutic procedures on bone (primarily removal of metal … than head and necka 202.0 322.7 110.5 176.4 38.5 Operations on the hemic and lymphatic system 64: Bone

113. PRCCSR-User-Guide-v2022-1 (pdf file)
     hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR-User-Guide-v2022-1.pdf
     October 01, 2021 - (5) Upper Veins (P) Upper Bones (6) Lower Veins (Q) Lower Bones (7) Lymphatic and Hemic Systems … Lower Bones Lower Joints Muscles Subcutaneous Tissue and Fascia Tendons Upper Bones Upper … codes with Root Operation (3rd character) Insertion or Removal, Body Part (4th character) Temporal Bone … , Right, Temporal Bone, Left, and Skull, and a Device (6th Character) Hearing Device are assigned to … rendering the articular body part immobile The body part is joined together by fixation device, bone

114. Neds 2015Q1Q3 Ed Maskedstats (pdf file)
     hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2015Q1Q3_ED_MaskedStats.PDF
     December 14, 2017 - marrow transplant <= 10 *.** 65: Bone marrow biopsy 45 0.00 66: Procedures on spleen <= 10 *.** 67 … Other therapeutic procedures on muscles and tendons 1,768 0.01 161: Other OR therapeutic procedures on bone … 206: Microscopic examination (bacterial smear, culture, toxicology) 336,569 1.70 207: Radioisotope bone … of bronchus; lung 2,609 0.01 20: Cancer; other respiratory and intrathoracic 14 0.00 21: Cancer of bone … connective tissue disorders 2,990 0.02 211: Other connective tissue disease 391,089 1.98 212: Other bone

115. Healthcare Cost and Utilization Project (HCUP) NIS Notes
     hcup-us.ahrq.gov/db/vars/dshospid/nisnote.jsp
     September 01, 2008 - records of general acute care stays from community hospitals are records from alcohol dependency units, bone … each patient record: None General acute care A= Alcohol Dependency Unit B= Bone

116. Healthcare Cost and Utilization Project (HCUP) KID Notes
     hcup-us.ahrq.gov/db/vars/dshospid/kidnote.jsp
     September 01, 2008 - records of general acute care stays from community hospitals are records from alcohol dependency units, bone … each patient record: None General acute care A= Alcohol Dependency Unit B= Bone

117. Clinical Classifications for Health Policy Research: Hospital Inpatient Statistics, 1995
     hcup-us.ahrq.gov/reports/natstats/his95/table2b.htm
     February 11, 2011 - 147,891 0.43 $27,937 $7,414 $12,888 $24,831 9.8 5.0 51.2 56 8.1 Bone … 8,896 0.03 $143,903 $69,210 $101,824 $179,038 28.8 8.6 41.4 40 8.2 Bone

118. Clinical Classifications for Health Policy Research: Hospital Inpatient Statistics, 1995
     hcup-us.ahrq.gov/reports/natstats/his95/appca.htm
     February 11, 2011 - respiratory and 20 - intrathoracic 2.11.3 Cancer of bone … - 1983 brain/spine 2.12.5 Secondary malignancy of bone

119. Facts and Figures Exhibit 5.8
     hcup-us.ahrq.gov/reports/factsandfigures/2007/exhibit5_8.jsp
     January 01, 2007 - degenerative joint disease) 279 455 43.3 48.4 63 Disorders of intervertebral discs and bones

120. Statistics from the HCUP-3 Nationwide Inpatient Sample for 1993: Diagnosis-Related Groups
     hcup-us.ahrq.gov/reports/natstats/93drgb.htm
     September 01, 1997 - 7.57 8,887 243 Medical back problems 245,111 0.71 5.24 5,583 244 Bone … & specific 23,193 0.07 8.16 7,915 arthropathies w/ CC 245 Bone … procedures w/o CC 480 Liver transplant 2,591 0.01 40.19 218,709 481 Bone