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1. PRCCSR ChangeLog v20221 v20231 (xls file)
   hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR-ChangeLog-v20231-v20241.xlsx
   December 01, 2023 - Cervical Vertebra using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach 'MST018' Bone … Lumbar Vertebra using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach 'MST018' Bone … 'CAR026' Pacemaker and defibrillator procedures 302A3H0 Transfusion of Autologous Whole Blood into Bone … Transfusion of blood and blood products 302A3N1 Transfusion of Nonautologous Red Blood Cells into Bone … Transfusion of blood and blood products 302A3P1 Transfusion of Nonautologous Frozen Red Cells into Bone

2. PRCCSR-ChangeLog-v20211-v20221 (xls file)
   hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR-ChangeLog-v20211-v20221.xlsx
   October 01, 2021 - Void Filler into Bones, Open Approach, New Technology Group 7 ADM015 Administration of antibiotics … Bone marrow aspiration (therapeutic) 07DT3ZZ Extraction of Bone Marrow, Percutaneous Approach LYM008 … (s) 1st Toe, Open Approach MST018 Bone excision 0QBN3Z2 Excision of Right Metatarsal, Sesamoid Bone( … , Sesamoid Bone(s) 1st Toe, Open Approach MST018 Bone excision 0QBP3Z2 Excision of Left Metatarsal, … , Sesamoid Bone(s) 1st Toe, Percutaneous Endoscopic Approach MST018 Bone excision 0NH003Z Insertion

3. Change Log (v2024.1 to v2025.1) for the Clinical Classifications Software Refined (CCSR) for ICD-10-PCS (xls file)
   hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR-ChangeLog-v20241-v20251.xlsx
   November 01, 2024 - from Nasal Bone, Percutaneous Approach MST012 Bone fixation (excluding extremities) 0NPB45Z Removal … of External Fixation Device from Nasal Bone, Percutaneous Endoscopic Approach MST012 Bone fixation ( … Device from Facial Bone, Percutaneous Approach MST012 Bone fixation (excluding extremities) 0NPW45Z … Facial Bone, Percutaneous Approach MST012 Bone fixation (excluding extremities) 0NWW45Z Revision of … Void Filler into Bones, Percutaneous Approach, New Technology Group 10 ADM021 Administration of therapeutic

4. PC-ICD10PCSChgLg-v20212-v20221 (xls file)
   hcup-us.ahrq.gov/toolssoftware/procedureicd10/PClassR-ChangeLg-v20212-v20221.xlsx
   December 01, 2022 - Marrow, Open Approach, Diagnostic 1 Minor Diagnostic 07DT0ZZ Extraction of Bone Marrow, Open Approach … (s) 1st Toe, Open Approach 4 Major Therapeutic 0QBN3Z2 Excision of Right Metatarsal, Sesamoid Bone(s … (s) 1st Toe, Open Approach 4 Major Therapeutic 0QBP3Z2 Excision of Left Metatarsal, Sesamoid Bone(s) … 1st Toe, Percutaneous Approach 4 Major Therapeutic 0QBP4Z2 Excision of Left Metatarsal, Sesamoid Bone … Void Filler into Bones, Open Approach, New Technology Group 7 4 Major Therapeutic XW133D7 Transfusion

5. Differences in Hospital Stays With Operating Room Procedures by Patient Race and Ethnicity, 2019 (pdf file)
   hcup-us.ahrq.gov/reports/statbriefs/sb297-OR-procedures-racial-disparities-2019.pdf
   January 01, 2019 - and other therapeutic heart procedures 16.7 13.2 15.8 11.8 15.4 9 Fixation of upper extremity bones … Gastrectomy 64.3 9.6 100.3 57.3 60.8 3 Appendectomy 51.0 28.9 38.8 63.7 47.0 4 Fixation of leg and foot bones …  White NH children had the highest rate of stays with bone fixation, spine fusion, bone excision, … upper gastrointestinal therapeutic procedures, and fixation of upper extremity bones. … years  Black NH adults had the highest rate of stays with gastrectomy, fixation of leg and foot bones

6. PClassR Change Log v20231-v20241 (xls file)
   hcup-us.ahrq.gov/toolssoftware/procedureicd10/PClassR-ChangeLog-v20231-v20241.xlsx
   April 01, 2024 - Percutaneous Approach 2 Minor Therapeutic 302A3J1 Transfusion of Nonautologous Serum Albumin into Bone … Percutaneous Approach 2 Minor Therapeutic 302A3K1 Transfusion of Nonautologous Frozen Plasma into Bone … , Percutaneous Approach 2 Minor Therapeutic 302A3L1 Transfusion of Nonautologous Fresh Plasma into Bone … , Percutaneous Approach 2 Minor Therapeutic 302A3N0 Transfusion of Autologous Red Blood Cells into Bone … Percutaneous Approach 2 Minor Therapeutic 302A3P0 Transfusion of Autologous Frozen Red Cells into Bone

7. PRCCSR-ChangeLog-v20221-v20231 (xls file)
   hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR-ChangeLog-v20221-v20231.xlsx
   November 01, 2022 - Administration of therapeutic substances, NEC 3E0V0GC Introduction of Other Therapeutic Substance into Bones … Administration of therapeutic substances, NEC 3E0V4GC Introduction of Other Therapeutic Substance into Bones … of Internal Fixation Device with Tulip Connector into Right Pelvic Bone, Percutaneous Approach, New … Device with Tulip Connector into Left Pelvic Bone, Open Approach, New Technology Group 8 MST012 Bone … , Percutaneous Approach, New Technology Group 8 MST012 Bone fixation (excluding extremities) XRGE058

8. Briefintrotoicd-10Codes041117 (pdf file)
   hcup-us.ahrq.gov/datainnovations/BriefIntrotoICD-10Codes041117.pdf
   April 11, 2017 - Subcutaneous Tissue & Fascia, (K) Muscles, (L) Tendons, (M) Bursae & Ligaments, (N) Head & Facial Bones … , (P) Upper Bones, (Q) Lower Bones, (R) Upper Joints, (S) Lower Joints, (T) Urinary System, (U) Female … Description ICD-10-PCS Description ICD Codes 01.25 Other craniectomy 0NT80ZZ Resection of left occipital bone … nervous system First two code characters 0N Medical and Surgical section of Head and Facial Bones … Corresponding CCS Category 1 Incision and excision of CNS 161 Other OR therapeutic procedure on bone

9. Pc2015
   hcup-us.ahrq.gov/toolssoftware/procedure/pc2015.csv
   January 01, 2012 - SEQUESTRECT 4 '7609' FACIAL BONE INCISION NEC 4 '7611' FACIAL BONE BIOPSY 3 '7619' FACIAL BONE DX … GRAFT NOS 4 '7801' BONE GRAFT TO CHEST CAGE 4 '7802' BONE GRAFT TO HUMERUS 4 '7803' BONE GRAFTRADIUS … /ULNA 4 '7804' BONE GRFT TO METACAR/CAR 4 '7805' BONE GRAFT TO FEMUR 4 '7806' BONE GRAFT TO PATELLA … 4 '7807' BONE GRAFTTIBIA/FIBULA 4 '7808' BONE GRAFTMETATAR/TAR 4 '7809' BONE GRAFT NEC 4 '7810' … BONE STIMPATELLA (Begin 1987) 4 '7897' INSER BONE STIMTIB/FIB (Begin 1987) 4 '7898' INSER BONE STIMMETA

10. Change Log (v2024.1 to v2025.1) for Procedure Classes Refined for ICD-10-PCS (xls file)
    hcup-us.ahrq.gov/toolssoftware/procedureicd10/PClassR-ChangeLog-v20241-v20251.xlsx
    November 01, 2024 - Endoscopic Approach 4 Major Therapeutic 0NPBX5Z Removal of External Fixation Device from Nasal Bone … , External Approach 2 Minor Therapeutic 0NPW05Z Removal of External Fixation Device from Facial Bone … , External Approach 2 Minor Therapeutic 0NWB05Z Revision of External Fixation Device in Nasal Bone, … Endoscopic Approach 4 Major Therapeutic 0NWBX5Z Revision of External Fixation Device in Nasal Bone, … Void Filler into Bones, Percutaneous Approach, New Technology Group 10 4 Major Therapeutic XW1337A

11. PC-ICD10PCSChgLg-v20222-v20231 (xls file)
    hcup-us.ahrq.gov/toolssoftware/procedureicd10/PClassR-ChangeLg-v20222-v20231.xlsx
    November 01, 2022 - Percutaneous Approach 2 Minor Therapeutic 3E0V0GC Introduction of Other Therapeutic Substance into Bones … , Open Approach 4 Major Therapeutic 3E0V4GC Introduction of Other Therapeutic Substance into Bones, … Major Therapeutic XNH7058 Insertion of Internal Fixation Device with Tulip Connector into Left Pelvic Bone … Percutaneous Approach, Diagnostic 1 Minor Diagnostic 3 Major Diagnostic 0NB13ZX Excision of Frontal Bone … Percutaneous Approach, Diagnostic 1 Minor Diagnostic 3 Major Diagnostic 0NBX3ZX Excision of Hyoid Bone

12. Exhibit 3.6. Orthopedic Procedures
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_3_6C.jsp
    January 01, 2005 - 7,200 198,400 596,200 1,114,000 1,225,500 251,300 142 Partial excision of bone … procedures 100.0 100.0 100.0 100.0 100.0 100.0 100.0 142 Partial excision of bone … 99,097 1,121 23,958 26,050 38,548 40,028 7,204 142 Partial excision of bone

13. Exhibit 3.6. Orthopedic Procedures
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_3_6B.jsp
    January 01, 2005 - dislocation of radius and ulna (lower arm) 81,000 80,800 -0.2 142 Partial excision of bone … or dislocation of radius and ulna (lower arm) 2,372 2,851   142 Partial excision of bone

14. Depression
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2006/2006_5_2b.jsp
    January 01, 2006 - complications 5% 16% Thyroid disorders 4% 12% Disorders of intervertebral discs and bones

15. Ccscategorynames(Fulllabels) (pdf file)
    hcup-us.ahrq.gov/toolssoftware/ccs10/CCSCategoryNames(FullLabels).pdf
    January 18, 2017 - peritoneum 19 Cancer of bronchus; lung 20 Cancer; other respiratory and intrathoracic 21 Cancer of bone … Other diagnostic cardiovascular procedures 63 Other non-OR therapeutic cardiovascular procedures 64 Bone … marrow transplant 65 Bone marrow biopsy 66 Procedures on spleen 67 Other procedures; hemic and lymphatic … new system (PCS) excludes diagnostic information from procedures) 207 Nuclear medicine imaging of bone … marrow transplant [64] 8.2 Bone marrow biopsy [65] 8.3 Procedures on spleen [66] 8.4 Other therapeutic

16. Ccslabelchangesforicd-9Ccs2014 (pdf file)
    hcup-us.ahrq.gov/toolssoftware/ccs10/CCSLabelChangesforICD-9CCS2014.pdf
    August 27, 2014 - ICD-10- PCS body system structure CCS 176 Other organ transplant Organ transplantation (other than bone … and monitoring Added Monitoring procedures instead of creating a new CCS CCS 207 Radioisotope bone … scan Nuclear medicine imaging of bone Updated to new terminology to be consistent with ICD-10-PCS

17. EXHIBIT 4.1 Costs for the Most Frequent Diagnoses
    hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_4_1A.jsp
    January 01, 2005 - Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones … Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones

18. Dx Pr Grps Formats
    hcup-us.ahrq.gov/db/tools/Dx_Pr_Grps_Formats.txt
    December 28, 2023 - reproductive system procedures, NEC' 'MST001' = 'MST001: Arthrocentesis' 'MST002' = 'MST002: Bone … Arthroplasty of other joint (excluding knee and hip)' 'MST009' = 'MST009: Fixation of upper extremity bones … ' 'MST010' = 'MST010: Femur fixation' 'MST011' = 'MST011: Fixation of leg and foot bones' 'MST012 … ' = 'MST012: Bone fixation (excluding extremities)' 'MST013' = 'MST013: Spine fusion' 'MST014' … = 'MST014: Joint fusion (excluding spine)' 'MST015' = 'MST015: Closed reduction of bones and joints

19. Dx Pr Grps Formats
    hcup-us.ahrq.gov/db/tools/Dx_Pr_Grps_Formats.TXT
    December 28, 2023 - = 'MUS027 : Musculoskeletal abscess' 'MUS028 ' = 'MUS028 : Other specified bone … joint (excluding knee and hip)' 'MST009 ' = 'MST009 : Fixation of upper extremity bones … = 'MST010 : Femur fixation' 'MST011 ' = 'MST011 : Fixation of leg and foot bones … ' 'MST012 ' = 'MST012 : Bone fixation (excluding extremities)' 'MST013 ' = … : Joint fusion (excluding spine)' 'MST015 ' = 'MST015 : Closed reduction of bones

20. Overview of Operating Room Procedures During Inpatient Stays in U.S. Hospitals, 2018 (pdf file)
    hcup-us.ahrq.gov/reports/statbriefs/sb281-Operating-Room-Procedures-During-Hospitalization-2018.pdf
    January 01, 2018 - 21.4 Ages 18–44 years 818,500 1,386.4 Ages 18–44 years 3,328,700 5,769.3 1 Fixation of leg and foot bones … 2,703 40,900 66,100 17 Decompressive craniectomy 437 46,700 9,400 18 Fixation of leg and foot bones … billion), arthroplasty of joint other than knee and hip ($2.8 billion), and fixation of leg and foot bones … 1 Spine fusion 851 7.0 24,400 1 Cesarean section 8,491 42.2 1,137,500 2 Fixation of leg and foot bones … musculoskeletal procedures ranked in the top five most costly principal OR procedures: fixation of leg and foot bones