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401. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - adults.1 RA causes inflammation of the synovial lining of joints, leads to progressive erosion of bone … RA is highly variable; some researchers have suggested defining early RA as before development of bone

402. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/reporting.ppt
     September 01, 2009 - Testosterone use in men and its effects on bone health. … Testosterone use in men and its effects on bone health.

403. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
     January 01, 2020 - outcome is fracture (given that many fractures occur in women with nonosteoporotic T-scores/ normal bone … For this reason, we will exclude outcomes reporting only on bone mineral density. Section II.

404. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/breastfeeding/research-protocol
     October 01, 2019 - outcome is fracture (given that many fractures occur in women with nonosteoporotic T-scores/ normal bone … associated with breastfeeding exposure.For this reason, we will exclude outcomes reporting only on bone

405. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
     December 06, 2010 - inflammation of the synovium (a thin layer of tissue lining a joint space) and progressive erosion of bone

406. Management of Renal Masses and Localized Renal Cell Carcinoma: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/renal-cancer/clinician
     December 01, 2019 - Cell Anal Cancer Systematic Review Aug 29, 2023 Radiation Therapy for Metastatic Bone

407. Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/venous-ulcers-treatment/research-protocol
     December 01, 2019 - rash, intolerance, allergy MRSA Clindamycin Also can treat anaerobes; allergy is rare; good bone … requires multiple daily dosing; GI intolerance Trimethoprim/sulfamethoxazole Inexpensive; good bone

408. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
     September 01, 2011 - Other adverse events considered included mortality, hepatitis, bone marrow suppression, nausea or vomiting

409. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
     July 01, 2010 - Side-to-side vs. tendon-to-bone fixation (n=1) Low The evidence was too limited to make a conclusion.

410. Dental Care for People With Sickle Cell Disease: A Rapid Response Literature Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sickle-cell-dental-rapid-response.pdf
     July 01, 2024 - and identifiable patterns, affecting the enamel structure, gingiva, and the mandibular and maxillary bones … Nerve compression resulting from inflamed or infarcted bone can give rise to paresthesia. … In response to a heightened erythropoietic drive in SCD, bone marrow expansion can lead to maxillary … Mechanisms underlying the adaptive pulp and jaw bone trabecular changes in sickle cell anemia Oral Diseases

411. Treatment of Osteoarthritis of the Knee: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
     June 15, 2016 - the progressive destruction of the articular cartilage that lines the knee joints, the subchondral bone … J Bone Joint Surg Am. 2013 Mar 6;95(5):385-92. doi: 1555390 [pii] 10.2106/JBJS.L.00206. … J Bone Joint Surg Am. 2004 Oct;86-A(10):2179-86. PMID: 15466726. 27.

412. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
     September 01, 2011 - An increased risk of bone fracture is now added to this list, although the strength of association is … not only enteric infections and pneumonia (reported in 2005 review) but also an increased risk of bone

413. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
     September 13, 2012 - include rash, intolerance, allergy MRSA Clindamycin Also can treat anaerobes; allergy is rare; good bone … requires multiple daily dosing; GI intolerance Trimethoprim/sulfamethoxazole Inexpensive; good bone

414. Surveillance & Identification of Triggers for Updating Systematic Reviews for the EHC Program (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
     August 01, 2012 - acute mucositis, late mucositis, acute dysphagia, late skin toxicity, late osteoradionecrosis, and bone … acute mucositis, late mucositis, acute dysphagia, late skin toxicity, late osteoradionecrosis, and bone

415. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
     January 01, 2015 - Vismodegib (Erivedge) for Advanced Basal Cell Carcinoma Radium-223 Dichloride (Xofigo) for Solid Tumor Bone … Radium-223 Dichloride (Xofigo) for Treatment of Solid Tumor Bone Metastases Radium-223 was FDA approved … high end, we estimated that 35% of patients with advanced prostate cancer with symptoms related to bone … Syndrome Morquio A syndrome is a rare, potentially fatal metabolic disorder that primarily affects bone … Pharmaceutical $2,000,000,000 1,600,000,000 Radium-223 Dichloride (Xofigo) for Treatment of Solid Tumor Bone

416. Gout Dx protocol_140715-draft (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
     January 01, 2014 - development of tophi (solid deposits of monosodium urate [MSU] crystals in joints, cartilage, and bones

417. Enzyme Replacement Therapy for Lysosomal Storage Disorders | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lysosomal-storage-diseases-therapies/research-protocol
     December 01, 2020 - develop visceral problems (hepatomegaly, splenomegaly), anemia, thrombocytopenia, lung disease, severe bone

418. Point-Of-Care Research (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
     April 01, 2014 - Young Adults 2012a Report43 0 Journal article44 0 Treatments to Prevent Fractures in Low Bone … Treatment to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis: Update of a 2007 … Treatment to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis: Update of a 2007

419. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - For example, in a recent Comparative Effectiveness Review on drugs to treat low bone density, the EPC … Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone Density

420. Avoiding Bias in Selecting Studies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-bias/methods
     August 01, 2019 - For example, in a recent Comparative Effectiveness Review on drugs to treat low bone density, the EPC … Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone Density or