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1. Bone Diseases | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-diseases
   August 29, 2023 - After about age 20, you can lose bone faster than you make bone. … To have strong bones when you are young, and to prevent bone loss when you are older, you need to get … Bone diseases can make bones easy to break. … Different kinds of bone problems include Low bone density and osteoporosis , which make your bones … of bone makes them weak Bones can also develop cancer and infections Other bone diseases,

2. Bone Density | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-density
   April 23, 2019 - Density Description Strong bones are important for your health. … A bone mineral density (BMD) test is the best way to measure your bone health. … It can show Whether you have osteoporosis , a disease that makes your bones weak Your risk for … breaking bones Whether your osteoporosis treatment is working Low bone mass that is not low enough … If you have low bone mass, there are things you can do to help slow down bone loss.

3. Osteoporosis-Bone-Fracture Executive (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
   March 01, 2012 - mass and microarchitectural deterioration of bone tissue, with consequent increases in bone fragility … maintenance of bone health. … When serum calcium levels are inadequate, bone tissue is resorbed from the skeleton to maintain serum … strength include bone mineral density and bone quality; some aspects of bone quality that might affect … J Bone Miner Res. 2003;18(6):1125-8. 13.

4. Bone Marrow Diseases | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-marrow-diseases
   August 29, 2023 - Marrow Diseases Description Bone marrow is the spongy tissue inside some of your bones, such … as your hip and thigh bones. … bone marrow doesn't make red blood cells In myeloproliferative disorders, the bone marrow makes too … Tests for bone marrow diseases include blood and bone marrow tests. … They might involve medicines, blood transfusions or a bone marrow transplant .

5. Radiation Therapy for Bone Metastases (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
   August 10, 2022 - location, whether they are osteolytic, osteoblastic, or mixed), the mechanical stability of the affected bones … Palliation of bone metastases-exploring options beyond radiotherapy. … The role of radiation therapy in bone metastases management. … A Further Analysis of the Dutch Bone Metastasis Study. … KQ1: ("bone metastases"[Title/Abstract] OR "bone neoplasms/radiotherapy"[MeSH Terms]) AND ("external

6. Bone Cancer | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-cancer
   August 29, 2023 - Cancer Description Cancer that starts in a bone is uncommon. … Cancer that has spread to the bone from another part of the body is more common. … The most common symptom of bone cancer is pain. … Surgery is often the main treatment for bone cancer. … Because bone cancer can come back after treatment, regular follow-up visits are important.

7. Bone Infections | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-infections
   Infections Description Like other parts of the body, bones can get infected. … They may spread to the bone from nearby skin or muscles, or from another part of the body through the … People who are at risk for bone infections include those with diabetes , poor circulation, or recent … injury to the bone. … , and redness A blood test or imaging test such as an x-ray can tell if you have a bone infection

8. Bone Marrow Transplantation | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/bone-marrow-transplantation
   Marrow Transplantation Description Bone marrow is the spongy tissue inside some of your bones … , such as your hip and thigh bones. … A bone marrow transplant is a procedure that replaces a person's faulty bone marrow stem cells. … This destroys the faulty stem cells in your bone marrow. … In some cases, you can donate your own bone marrow stem cells in advance.

9. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/osteoporosis-bone-fracture/research-protocol
   March 01, 2020 - mass and microarchitectural deterioration of bone tissue, with consequent increases in bone fragility … Osteoporosis is diagnosed by assessing bone mineral density (BMD). … Low bone mass or density is defined as a T-score between -2.5 and -1. … America’s bone health: The state of osteoporosis and low bone mass in our nation. … J Bone Miner Res. 2007 Mar;22(3):465-75. National Osteoporosis Foundation.

10. Technical Brief: Whole Body Vibration Therapy for Osteoporosis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoporosis-vibration-therapy/research-protocol
    December 01, 2019 - mass and deterioration of bone tissue. 1 Osteoporosis is a significant public health problem that leads … tissue, directly activating mechanosensors in bone cells.33 Animal studies demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone density. 24,34-36 … Vibration exercise makes your muscles and bones stronger: fact or fiction? … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

11. Topic Brief: Radiation Therapy for Bone Metastases (pdf file)
    effectivehealthcare-admin.ahrq.gov/system/files/docs/topic-brief-radiation-therapy-bone-metastases.pdf
    August 01, 2022 - Topic Brief: Radiation Therapy for Bone Metastases 1 Topic Brief: Radiation Therapy for Bone … (bone metastasis). … A 2020 population-based study of patients with bone metastases found that the incidence of bone metastases … neoplasms/sc (19257) 2 bone metastas*.ti,ab,kf. (17492) 3 or/1-2 (27965) 4 bone neoplasms/rt or ( … In a 2020 population- based study of patients with bone metastases, the incidence of bone metastasis

12. Cer-265-Radiation-Bone-Disease-Addendum-App (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    October 12, 2023 - controlled trial evaluating external beam radiation therapy for the palliative treatment of metastatic bone … Analyzed at Final Follow-Up, Attrition Intervention, Comparator Prior and Concurrent Treatments Site of Bone … Metastases Characteristics of Bone Metastases Primary Tumor Histology Age, Mean Overall Population Sex … Asian: 4.4% Other: 1.2% Not reported/ unknown: 2.9% NR Comorbidities: NR Duration of pain: NR Non-bone

13. Cer-265-Radiation-Bone-Disease-App-F (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
    January 01, 2019 - controlled trials evaluating external beam radiation therapy for the palliative treatment of metastatic bone … No Unclear Unclear Unclear Yes Fair Badzio, 2003 Yes Yes Yes No No No Yes Yes Yes Unclear Yes Fair Bone … (Sprave, 2018 above) Unclear Unclear No Unclear No No Yes No Yes No Yes Fair Steenland, 1999 Dutch Bone … (subsequent publication) NA NA Yes Unclear No No Yes No Yes NA Yes Fair van der linden, 2004 Dutch Bone … interventions evaluating external beam radiation therapy for the palliative treatment of metastatic bone

14. Osteoporosis-Vibration-Therapy Research-Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
    January 01, 2020 - mass and deterioration of bone tissue.1 Osteoporosis is a significant public health problem that … tissue, directly activating mechanosensors in bone cells.33 Animal studies demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone http://www.effectivehealthcare.ahrq.gov … Good, good, good... good vibrations: the best option for better bones? … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

15. Osteoporosis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/osteoporosis
    February 19, 2025 - Osteoporosis Description Osteoporosis is a disease that thins and weakens the bones … Your bones become fragile and break easily, especially the bones in the hip, spine, and wrist. … You might not know you have it until you break a bone. … A bone mineral density test is the best way to check your bone health. … To keep bones strong, eat a diet rich in calcium and vitamin D , exercise, and do not smoke.

16. Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/research
    December 01, 2023 - Home Evidence Reports Radiation Therapy for Metastatic Bone … SHARE: Radiation Therapy for Metastatic Bone … For symptomatic adults with bone metastases who will receive initial radiation for palliation, what is … For symptomatic adults with bone metastases who will receive re-irradiation for palliation, what is the … Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms.

17. Whole-Body Vibration Therapy for Osteoporosis (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
    January 01, 2020 - tissue. … density and deterioration of bone tissue.1 The clinical ranges for osteoporosis, osteopenia, and normal … tissue, directly activating mechanosensors in bone cells.40 Animal studies have demonstrated that vibration … increases the anabolic (bone building) activity of bone tissue and increases bone density.26,41-43 … The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely

18. Radiation Therapy for Bone Metastases | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases
    January 20, 2022 - SHARE: Radiation Therapy for Bone

19. Radiation Therapy for Bone Metastases | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/protocol
    August 01, 2022 - location, whether they are osteolytic, osteoblastic, or mixed), the mechanical stability of the affected bones … Palliation of bone metastases-exploring options beyond radiotherapy. … The role of radiation therapy in bone metastases management. … 3: Symptomatic adults with cancer that has metastasized to the bone. … KQ1: ("bone metastases"[Title/Abstract] OR "bone neoplasms/radiotherapy"[MeSH Terms]) AND ("external

20. Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoporosis-bone-fracture/research
    October 01, 2020 - Evidence Reports Treatment To Prevent Fractures in Men and Women With Low Bone … SHARE: Treatment To Prevent Fractures in Men and Women With Low Bone … Effect of ipriflavone on bone in elderly hemiplegic stroke patients with hypovitaminosis D. … Project Timeline Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis … https://effectivehealthcare.ahrq.gov/products/osteoporosis-bone-fracture/research