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401. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
     January 01, 2013 - living document, and will be updated as further empiric evidence develops and our understanding of better … report details guiding principles and methodological recommendations that may help investigators to better … Refinement implies making changes to attain a better fit with a certain standard. … The purpose of this literature scan is two-fold: (1) to help the investigators better understand the … The principal dilemma relates to DMARDs and not corticosteroids; this makes them better suited as

402. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - Peer Reviewer #1 General This report leaves the clinician with little direction as to how to better … I would suggest the term ‘recurrence’ needs to be better defined in the discussion. … Given the adverse outcomes know from DHE and triptans would it not have been better for the reader to … I do not know if the authors could have done better however given the quality of the literature reviewed … Ultimately it doesn't tell me something I don't already know (i.e. active treatment is better than placebo

403. Phenylketonuria Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
     February 01, 2012 - The Phe level obtained more than 1 year before IQ testing is likely to be a better indicator of how … One basic need is to better understand the degree to which the perceived association changes by age, … This highlights the need for fundamental research, because measures of executive function tend to be better … For example, a better understanding is needed of the effects of BH4 in children less than 4 years of … The Phe level obtained more than 1 year before IQ testing is likely a better indicator of how well

404. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better … diagnoses, such as AD versus frontotemporal dementia (FTD); and (2) to enrich clinical trials seeking better … and for drugs, biologics, and alternative or complementary interventions that modify the disease or better

405. Quality-Gap-Palliative-Hospice Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
     October 01, 2012 - this field could be improved by recruitment and retention efforts to assure adequate sample size, better … this population has advanced, but more development is needed for measuring certain domains and to better … settings and providers, and following patient populations over longer periods of time, will be needed to better

406. Kravitz_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
     January 01, 2012 -  Code o A set of standards that are applied to health Internet sites that might help consumers better

407. Naik (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/naik.pdf
     January 01, 2009 - Naik Slide 1: Using  Electronic Health Records  to Better

408. Atrial-Fibrillation-Addendum-140619 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-addendum-140619.pdf
     June 19, 2014 - Standard of Care (Mitral Valve Surgery) or AADs” to better reflect the overlap of these categories/interventions

409. Future Research Needs for Childhood Obesity Prevention Programs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
     March 31, 2010 - More vigorous analytic approaches are desirable in future studies, to better analyze the repeated measures … These included the need for better evaluation of community-based studies, attention to barriers and … support the need for improved methods for the evaluation of community based interventions as well as better … More vigorous analytic approaches are desirable in future studies, to better analyze the repeated measures … barriers and facilitators to implementing programs 3 More rigorous analytic approaches (i.e., to better

410. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better … interest in natural orifice transluminal endoscopic surgery (known as NOTES) if it can demonstrate better … , POEM could renew interest in NOTES procedures and instrumentation if ongoing trials demonstrate better … procedures and instrumentation because it is the only procedure demonstrating potential to have better … of teduglutide, prescribed by a gastroenterologist, could help patients with poor access to care better

411. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - The evidence showing that better intermediate outcomes (e.g., symptoms) improve health outcomes (e.g … Without better evidence specific to this population, the balance of benefits and harms is uncertain … The evidence on functional outcomes for the mother is also insufficient, although it leans toward better … Comparisons of specific treatments in pregnancy are badly needed to better uncover variation in risk … Research in this area needs to measure both benefits and harms simultaneously, so that results can better

412. Improving Health Care and Palliative Care for Advanced and Serious Illness Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
     October 01, 2012 - In order to better highlight that future research is needed both in diverse populations and in the … have reorganized the strength of evidence tables by separating out RCTs from non-RCTs which should better … have reorganized the strength of evidence tables by separating out RCTs from non-RCTs, which should better … Recommend replacing with “palliative care” or "serious life-limiting illness care" which is far better … We have rephrased this section to not seem as though we are dismissing these studies, but to better

413. Venous-Ulcers-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
     January 01, 2014 - A single study found that Short Form-36 scores were better after receiving CHIVA than after receiving … compression alone.48 The other study found that SEPS did not perform better than compression alone … finding does not necessarily mean that the interventions are ineffective, but rather that we need better … The objective would be to develop better standards for disease definition, interventions, comparison … These experts could create templates for study designs that better demonstrate efficacy.

414. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
     January 01, 2015 - Metformin, in my opinion, needs to have a better formulated qualitative discussion. … TEP Reviewer #3 General Need better clarity on whether comparative studies that include insulin are … TEP Reviewer #4 General Embedded; the labels for the figures are much better in the main paper than … Lines 38 and 39 discuss the need for better evidence on the effects of intensive glucose control and … We agree that better quality assessment tools have been developed since then.

415. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - Longer would not be better. … This proportion will grow even smaller once more effective and better tolerated therapy is available … Additionally, these patients presumably have a better long-term natural history and thus have less to … More research is also needed on the experiences of persons testing positive to better understand the … s Given the importance of the CDC's study to achieve the goal of better identification and treatment

416. Disposition of Comments for Comparative Effectiveness Review No. 240: Treatments for Acute Pain: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
     December 29, 2020 - Additional detail provided in the results to better describe studies and findings (e.g., duration of … The addicts get better pain relief than we do." Thank you for sharing your story. … I believe better and more consistent studies are needed before imposing pain and suffering on post … in some individuals and NSAIDs perform better in other individuals. … Opioids do not perform better or worse than NSAIDs for particular *conditions,* they perform better

417. Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
     August 01, 2016 - Having a better understanding of the role of these and other patient factors in postdischarge outcomes

418. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - How could a risk assessment tool lead to better outcomes other than through the more appropriate use … Better wording might be “If such interventions are truly effective, they would be expected to result … It might be better to avoid this term unless a precise definition is provided. … Since the “patient characteristics” column refers to groups A and B, it might be better to have the … They all are adequate to a certain degree, but we can't get them better.

419. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
     February 01, 2012 - The objective of this FRN is to establish better evidence about the costs and benefits of alternative … These analyses can help maximize early effective, tolerable treatment, to better match treatments to … Stakeholder Discussion The objective of this research need is to establish better evidence about the … The discussants agreed that it would be a better use of research resources to conduct large RCTs that … The patient advocates on the stakeholder panel described a demand by patients for better training,

420. White Paper: Living Systematic Reviews: Practical Considerations for Adapting Scope and Communicating the Evolving Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
     June 01, 2025 - To better inform decisions about adapting or expanding the scope, we performed a horizon scan by searching … To better understand the impact and usefulness of these efforts, we sought feedback from the TEP on … explore opportunities to obtain input from users of the report who are not members of the TEP, to better