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361. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
     September 01, 2012 - the SLFC assay’s impact on diagnostic accuracy in undiagnosed patients, as well as whether it is a better … predictor of outcome or progression of MGUS to MM, a better indicator for therapeutic decisionmaking … predictor of outcome or progression of MGUS to MM, a better indicator for therapeutic decisionmaking … Similarly, there was no evidence to ascertain whether SFLC response was a better predictor of outcomes … Superior overall survival of patients with myeloma achieving very good partial response or better to

362. CER 225: Evidence Summary Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
     May 01, 2020 - Future studies should evaluate outcomes that are most meaningful to adolescents, such as better functioning

363. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
     October 30, 2019 - We have modified the tables in KQ1 and KQ2 to better highlight the event rates for the various outcomes … no association”, for both individual studies and synthesized results, be reviewed and revised to better … help to round out the discussion of the CHADS2 versus CHA2DS2-VASc and provide clinicians with a better … it might be better to have used a smaller sample size threshold but restrict to studies that performed … Similar to KQ1, we now try to structure the tables in KQ2 to allow better comparison of the scores

364. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - know what to make of the series of tables F, G, H in which not ONE comparison had an overall rating better … Also, and allowable attrition rate of 50% is too high, 30% would be better. … among practitioners doing biopsies (and among manufacturers of equipment) appears to be “more is better … Perhaps our resources could have been better spent. … Do these correlate with better outcomes?

365. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
     January 01, 2017 - quality outcomes, limiting the ability to compare effectiveness directly across studies, although better … Time to return to normal diet was significantly better for children receiving acetaminophen compared … Better data regarding optimal medication regimens are essential, both in terms of symptomatic relief … A better understanding of these factors would allow for more specific patient selection. … Relative to no intervention, most studies reported better sleep-related outcomes in children with OSDB

366. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
     September 01, 2011 - Better to compare all non-personal modalities, then separately, various detailed forms of personal … VNS has a slow onset of response, but that responses are durable, and that the clinical effects are better … broad messages that future investigators should choose a standard definition of TRD and engage in better … Conclusion Page 24 in the right column "In post-stroke depression, rTMS groups had significantly better … On average, they responded better to long-term dynamic therapy than to other interventions [the average

367. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better … offsets of other health care costs from improved outcomes from the drug will help to elucidate and better … systems expert noted that additional clinical trials evaluating quality of life should be performed to better

368. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
     October 01, 2011 - Currently, it is unclear whether screening and early treatment for thyroid disease is better than not … indicate that, in elderly individuals, a mildly high TSH may be a predictor of longevity and possibly of better … strategies—routine or selective treatment vs. active surveillance—is needed to determine which strategy has better

369. Binge-Eating Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
     December 01, 2015 - the information produced in this review is intended to contribute to improved care for patients, better … As a class, antidepressants were associated with better binge-eating outcomes than placebo: abstinence … BWL produced better BMI outcomes than CBT at end of treatment (moderate strength of evidence), but … Similarly, longer trials might help clarify what treatments provide better outcomes with fewer side … effects and are better for patients who do not fully recover but live with a chronic illness.

370. Disposition of comments for CER 169 Low Back Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
     February 29, 2016 - None are dramatically better than others or placebo, though some have important benefits and some have … Consider adding table/figures (by pain categorization) that provides a better “visual” to display results … Motor control exercise was also associated with better function in the short and long term. … We explained that we stratified in this way to provide readers with better gradation of results and … Related to this observation, the outcomes appear somewhat better for "motor control exercise" than

371. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
     July 01, 2023 - provide benchmarks intended to spur local and larger-scale quality improvement efforts to produce better … With support from ACS NSQIP, individual sites work to design quality initiatives to achieve better

372. EHC Research Protocol: Documentation Burden (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-protocol.pdf
     July 26, 2023 - Beyond gaining a better understanding of how patients view clinical documentation burden on clinicians … and themselves, it is important to better understand the extent to which patients contribute to documentation

373. Disposition of Comments: Technical Brief 34, Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-34-health-worker-certification-comments.pdf
     March 27, 2020 - Once we have clearly described these goals at the outset of the report, the reader is better positioned … Accrediting a CHW program goes beyond training and seems like a better approach.

374. Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
     May 29, 2013 - It makes me wonder if the results might be better presented in a few different summaries. … That’s fine but what they really should recommend is better quality studies to assess the specific risk … Reviewer 15 General This would be much better presented as a whole series of smaller reports on each … Thus, the conclusion is perhaps self-evident ... there is a significant need for better-designed studies … We agree that there is a need for better- designed studies in these populations.

375. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better … clinical interest in natural orifice transluminal endoscopic surgery (NOTES) if it can demonstrate better … POEM could renew interest in NOTES procedures and instrumentation if the procedure can demonstrate better … increase the size and density of intestinal villi in the intestinal epithelial layer, resulting in better … of teduglutide, prescribed by a gastroenterologist, could help patients with poor access to care better

376. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - Number of Comparisons Comparators Effect Size (SMD) (95% CI) Strength of Evidence Pain (lower is better … 0.73 to -0.34) High 4 Oral estrogens vs. placebo -0.22 (-0.35 to -0.09) Moderate Global (higher is better … 0.01 to 0.52) Insufficient 4 Isoflavones vs. placebo 0.24 (-0.12 to 0.61) Low Interest (higher is better … Pain, interest, global 10 Estrogen route a vs. route b Not estimated Moderate Activity (higher is better … and Policy Decisionmaking The implications of this review for clinical decisionmaking follow from better

377. S5 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
     October 01, 2007 - For that reason, regulators, researchers, and the public are increasingly calling for better ways to … influ- ence the occurrence of the adverse event, not by factors that influence the outcome, may be the better

378. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - Veterans Administration pharmacy benefit.1 Alternative coverage is deemed creditable if it is equal to or better … hole in many Medicare plans, most veterans will find that the VA pharmacy benefit is equivalent or better

379. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - We appreciate that having better information about non-hospital use of rFVIIa would have been optimal … While the assumption that cessation of bleeding should lead to better direct patient outcomes has a … Could this paragraph explain this a little better? … Since there are not many MAs performed in this CER, it would be better to change the measure to risk … Results Page 38, age and gender distribution: a table or a figure could be a better way to present the

380. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
     August 24, 2012 - I would like the paper better if it was shorter and focused on only those studies where we really learn … It is speculative, of course, whether these new models will work better than the old, but the fact … Peer Reviewer #3 p. 75 lines 36-43: Diff 8 off studies should be better. … Otherwise we do not know if the bundle has accomplished the goal of better care and better quality, … These projects could better inform future adoption of these payment mechanisms.