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121. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
     January 01, 2009 - therapeutic efficacy (E-2), the change in therapy planning; and outcome efficacy (E- 3): Was the patient better … performed once a technology has gained marketing approval; these studies address long-term safety and better … in disease for which there is no clinical reference standard or when the new test is thought to be better … much net gain from testing there will be for the patient in terms of improved treatment decisions and better … Why we need better test evaluations. Clin Chem 1982;28:1272-1276. 24. Sackett DL, Haynes RB.

122. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
     September 01, 2008 - lowering profile that more closely mimics the physiology of a person without diabetes, thus providing better … Clinicians may be better able to choose the most effective therapy for their patients with diabetes if … • Clinical outcomes need to be studied in order to better evaluate the safety of premixed insulin analogues … Postprandial glucose Long-acting insulin High Premixed insulin analogues are better than long-acting … insulin analogues (basal-bolus regimen) Premixed human insulin High Premixed insulin analogues are better

123. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
     January 01, 2009 - therapeutic efficacy (E-2), the change in therapy planning; and outcome efficacy (E- 3): Was the patient better … performed once a technology has gained marketing approval; these studies address long-term safety and better … in disease for which there is no clinical reference standard or when the new test is thought to be better … much net gain from testing there will be for the patient in terms of improved treatment decisions and better … Why we need better test evaluations. Clin Chem 1982;28:1272-1276. 24. Sackett DL, Haynes RB.

124. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
     April 25, 2013 - With better descriptions of assumptions and limitations in this section, readers can make more informed … Does better outcomes refer specifically to transfusion-sparing effect ? … Furthermore, the sources of the estimations need to be better described and made more explicit. … Page 99, line 27: Suggest saying this as "...slightly better scores..." or "...modestly better scores … We have adopted the use “better.” The word “biologically” has been deleted.

125. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - Some of our suggestions include (1) Information on how better-quality observational studies can be … The review could also note the need for better prognostic surrogate markers--biochemical progression … We have also added to the Research Gaps section the need for better prognostic surrogate markers to … Perhaps policy and practice decisions will be better informed once it is possible to better define … We have reworded our entire qualitative analysis throughout the report for better clarity.

126. Appendix-E-Table-E5 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
     May 29, 2025 - difference −1.09 (95% CI −10.33 to 8.16) SF-36 Functioning (mean [SD], 0 to 100 scale, higher scores are better … B SF-36 General Health (mean [SD], 0 to 100 scale, higher scores are better) 62.92 (18.38) vs. 55.56

127. Cannabis-App-F5-Table-Surveillance-Report-2 0 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
     May 29, 2025 - difference −1.09 (95% CI −10.33 to 8.16) SF-36 Functioning (mean [SD], 0 to 100 scale, higher scores are better … B SF-36 General Health (mean [SD], 0 to 100 scale, higher scores are better) 62.92 (18.38) vs. 55.56

128. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
     June 01, 2012 - Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency

129. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
     June 01, 2012 - Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency … Better information for better health care: the Evidence-based Practice Center Program and the Agency

130. Radiotherapy Treatments for Head and Neck Cancer Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_disposition.pdf
     December 09, 2014 - The explanation of the Setting is much better in Table E. 2. - p.17, Fig. … This process is very powerful and allows for much better plans – better blocks, better beam angles … The SBRT description should be much better. … Reasonable but should be better described. 4. … Use PBT instead, which is the accepted acronym (for better or worse). 5.

131. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - Reviewer 3 ES: Botulinum toxin was better than placebo in reducing monthly migraine attack by ≥50 … The drugs were not better than placebo in planned intention to treat analysis of all randomized patients … Reviewer 3 Report: Topiramate was also better than placebo in reducing monthly migraine days by ≥50 … Report, Results: Absolute reduction in migraine days with topiramate, 50 to 200 mg/day, was not better … Comparative effectiveness trials should examine the drugs that had been shown efficacy (better than

132. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
     March 15, 2016 - same outcomes regardless of agent, i.e. increased rejection, but to be fair on treatment groups show better … on daclizumab induction 2 g mycophenolate mofetil MMF lowdose tacrolimus and steroids resulted in better … It might be better to refer to these regimens as "other-than full dose" or "off-label" regimens. … We hope that more studies of better methodological quality will become available to provide clearer … We identify the need for better data on lesser reported outcomes as an important area for future

133. Topic 0545 Behav Health Int for Dementia NSD FINAL SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_644-03-07-2013.pdf
     January 01, 2013 - nominator asserts that a product on the nominated topic could support clinical guidelines and provide a better

134. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0272_03-06-2008.pdf
     January 01, 2008 - What other modalities of treatment, including weight loss, surgery, and oral appliances, would be better

135. Disposition of Comments Report for Medication Adherence Interventions: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_disposition-comments.pdf
     September 11, 2012 - Reorganization of the results so that readers can better follow the main findings would be helpful. … The abstract would read better if the same general structure was adopted- where first intervention by … the exclusion numbers with reasons (as was done for the full-text articles) would help the reader better … By including some studies that used quasi-experimental design, it may allow a better understanding … We have revised the abstract to ensure better signposting, as noted above.

136. Disposition of Comments for Treatment of Glaucoma: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
     April 01, 2012 - Conversely, in the latter instance, an individual can do no better than hold steady or deteriorate … is on comparative effectiveness so we were looking for evidence either that treatment resulted in better … It is the balance of the benefits and harms that needs to be better evaluated. … Treatment of OHT and OAG was found to lead to better preservation of VF compared with observation. … Trabeculectomy showed better preservation of VF compared with the other two modalities.

137. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better … Better treatments to prevent COPD exacerbations are needed. … concern about antibiotic resistance with ongoing daily use and whether other macrolides would be better … Developing new strategies to better preserve or improve donor-lung quality could affect the number … Better treatments to prevent COPD exacerbations are needed.2 Intervention: Azithromycin (Zithromax

138. Disposition of Comments for Technical Brief 31 Mobile Applications for Self-Management of Diabetes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt-disposition-comments.pdf
     May 08, 2018 - This is a better way to express our key message #1, so we have revised accordingly. … studies, less than half showed improvements in an important lab test for monitoring diabetes This is a better … this brief can and should be used to galvanize the diabetes community around promoting the tools for better … We hope that the report highlights the most important limitations of the literature so there are better … Key Informant #3 Clarity & Usability I am hopeful that the report will encourage better reporting

139. The series of articles beginning with this issue of the Journal form the most up-to-date version of the Guide for Conducting Comparative Effectiveness Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-principles_methods.pdf
     August 01, 2009 - living document, and will be updated as further empirical evidence develops and our understanding of better … patient-centeredness, the Program encourages EPCs to use absolute measures whenever possible to promote better … randomized clinical trials and to suggestions for changing or expanding the hierarchy of evidence to take better … Better information for better health care: The Evidence-based Practice Center Program and the Agency

140. Disposition of Comments Report for Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
     January 01, 2011 - translate what it means when they say: "there is a low level of evidence that CHr has similar or better … compared to traditional ones when considering treatment of a patient subpopulation clearly in need of better … Nevertheless, future studies aimed at reducing the research gaps hold the promise for adoption of better … that affect the biological variability of these tests, and, as a result, that there is a need for better … deficiency, I do not believe that necessarily predicts response to iron, safety of the approach or better