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461. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
     January 01, 2013 - AHRQ convened a work group to assess current approaches and to develop recommendations for best practices … Based on an assessment of the experience of various EPCs, to identify best practices and incorporate … By producing a more detailed description of topic refinement, including guiding principles and best … Each approach has its own advantages and disadvantages, and EPCs should consider which approach best … Determining the best size and composition of interview groups involves balancing the factors mentioned

462. Skin Substitutes for Treating Chronic Wounds | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/skin-substitutes/protocol
     January 01, 2020 - published since the 2012 AHRQ report Skin Substitutes for Treating Chronic Wounds , and suggest the best … What best practices in study design could be used to produce high quality evidence on skin substitutes … Ongoing clinical trials sourced from the grey literature and KI input on best practices will help inform

463. Management of Renal Masses and Localized Renal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/renal-cancer/research-protocol
     December 01, 2019 - such models have modest concordance indices for malignancy in the range of 0.55 to 0.65. 3, 16-18 The best … has comparable oncologic outcomes to partial nephrectomy, although it is not clear which patients are best … This was largely based on expert opinion and best-available studies that were observational and retrospective … Determining the best approach to management of clinically-localized renal masses is a complex task. … T1a tumors, specifically, have the best prognosis and define a category of tumors in which nephron-sparing

464. Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dementia-nursing-home-characteristics/research-protocol
     December 01, 2019 - and there is no comprehensive evidence-based guidance on which type or characteristics of setting is best … consumer/patient guides are available to help the public choose the type of LTC setting that may be best … The authors recommended implementing best practice rather than providing a specialized care environment … LTC settings for people with dementia—addresses uncertainty for families that are trying to make the best … f Taking a “best evidence” approach, if evidence is insufficient for the main interventions and comparisons

465. Grading_didactic_faculty_approved (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/grading.ppt
     January 01, 2013 - Apart from deciding how best to proceed, reviewers need to understand that this is a complex step requiring … Reference: Atkins D, Best D, Briss PA, et al, for the GRADE Working Group. … References: Atkins D, Best D, Briss PA, et al, for the GRADE Working Group. … References Atkins D, Best D, Briss PA, et al, for the GRADE Working Group. … DOI: 10.1016/j.jclinepi.2009.03.009 References Atkins D, Best D, Briss PA, et al, for the GRADE Working

466. Living Systematic Reviews: Practical Considerations for the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
     March 01, 2022 - particularly helpful as the review team engaged with the technical expert panel and considered how best … A “best evidence” approach was initially proposed, where observational studies would help fill gaps … Future changes in scope may require additional decisions on how to best incorporate them.

467. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
     October 01, 2010 - This method provides the least biased, most powerful combined estimates with the best confidence interval … Estimates accounted for within-individual correlation are best for meta-analysis. … Similarly for cluster randomized trials, estimates accounted for intra-cluster correlation are best for

468. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
     October 01, 2010 - This method provides the least biased, most powerful combined estimates with the best confidence interval … Estimates accounted for within-individual correlation are best for meta-analysis. … Similarly for cluster randomized trials, estimates accounted for intra-cluster correlation are best for

469. Conducting Quantitative Synthesis When Comparing Medical Interventions: AHRQ and the Effective Health Care Program | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-quantitative-synthesis/methods
     December 01, 2019 - This method provides the least biased, most powerful combined estimates with the best confidence interval … Estimates accounted for within-individual correlation are best for meta-analysis. … Similarly for cluster randomized trials, estimates accounted for intra-cluster correlation are best for

470. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
     April 06, 2010 - Question At the completion of our review, we will grade the quantity, quality and consistency of the best … We will assess the strength of the study designs with RCTs considered best, followed by non-RCTs, and … We will assess the quality and consistency of the best available evidence, including assessment of limitations

471. What is the efficacy and comparative effectiveness of pharmacological and nonpharmacological treatments for adults with schizophrenia What are the harms from pharmacological and nonpharmacological treatments for adults with… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-efficacy-and-comparative-effectiveness-of-pharmacological-and-nonpharmacological-treatments-for-adults-with-schizophrenia-what-are-the-harms-from-pharmacological-and-nonpharmacological-treatments-for-adults-with-
     November 01, 2017 - Other Information About You: (optional) Please choose a description that best describes your role

472. Which interventions are effective in decreasing heart failure readmissions? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/which-interventions-are-effective-in-decreasing-heart-failure-readmissions
     November 01, 2017 - Nominator Information Other Information About You: (optional) Please choose a description that best

473. What are the comparative diagnostic accuracy, diagnostic thinking, therapeutic, and patient outcome efficacy of non-invasive tests for the risk stratification of patients with coronary artery disease? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease
     November 01, 2017 - Nominator Information Other Information About You: (optional) Please choose a description that best

474. Population: Children < 18 years of age: 1. What are the incidences and prevalences of non-inflammatory pain syndromes (e.g., benign hypermobility syndrome, patellofemoral stress syndrome, fibromyalgia, and growing pain) in children and… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/population-children-18-years-of-age-1-what-are-the-incidences-and-prevalences-of-non-inflammatory-pain-syndromes-eg-benign-hypermobility-syndrome-patellofemoral-stress-syndrome-fibromyalgia-and-growing-pain-in-children-and-a
     November 01, 2017 - Nominator Information Other Information About You: (optional) Please choose a description that best

475. EPC Methods: An Exploration of Methods and Context for the Production of Rapid Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/rapid-review-production/white-paper
     November 01, 2017 - present summaries or conclusions; (2) ”rapid responses” present the end-user with an answer based on the best

476. Hip-Fracture-Pain Consumer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_consumer.pdf
     May 01, 2011 - Which options do you think are best to manage my pain? 2.

477. Asthma-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
     May 01, 2011 - FEV1 of 12 percentage points, compared with only two percentage points in the control group.34 The best … in participants who underwent IMT than those who did not (Table A).36-38 These data, however, are best … The best quality trial of yoga conducted in India showing large benefits of treatment reported that … health care systems was the best (although still limited, since no trials were conducted in the United … Best practices regarding randomization, blinding, and followup are also crucial to any further research

478. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - , it has been suggested that the rate of “inappropriate” prescription of antibiotics would be the best … Data Synthesis We used a hierarchy-of-evidence approach that focused on the best evidence for each … Although the best evidence to date supports the use of four interventions from all categories outlined … Unfortunately, the evidence was inadequate to guide selection of the best intervention for a given … Conclusions The best evidence supports the use of specific education interventions for patients/parents

479. Arcia-notes-Teresa (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/arcia-presentation.pdf
     November 11, 2015 - really didn't see much   in  the literature that would  give us any guidance as to what is the best … "Of these three, which  one do you   like the best? How would  you   improve it?"

480. FRN 30: Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
     June 01, 2015 - intervention are often not provided, current research evidence cannot answer questions about how to best … intervention are often not provided, current research evidence cannot answer questions about how to best … For presentation purposes, we grouped topics together by the PICOTS that they best addressed as well … Case management: what it is and how it can best be implemented. … Case management: what it is and how it can best be implemented.