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441. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
     March 10, 2010 - The best studies for testing this assumption involve direct comparisons of ACEs and ARBs, and there … Conclusions may best be described using the name of the specific ARB from which the information was … that this provides the greatest amount of transparency and people can view and use the analyses that best

442. Glaucoma-Treatment Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/glaucoma-treatment_research-protocol.pdf
     November 16, 2010 - controlled trials, our evidence grade will be based on the single randomized controlled trial and the best … We will assess the quality and consistency of the best available evidence, including assessment of the … Atkins D, Best D, Briss PA, et al. Grading quality of evidence and strength of recommendations.

443. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
     November 16, 2010 - controlled trials, our evidence grade will be based on the single randomized controlled trial and the best … We will assess the quality and consistency of the best available evidence, including assessment of the … Atkins D, Best D, Briss PA, et al, for the GRADE Working Group.

444. renal-update-2015-150115 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
     January 15, 2015 - stenting in selected cases.10 Especially given the inconclusive evidence to date, it is important to best … understand which patient characteristics and other factors may best predict which patients are likely … to do best with which intervention.

445. Assessing Applicability (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
     January 01, 2009 - Applicability is best reported separately from quality or strength of evidence. … Strength of Evidence Separately Judge Applicability and Strength of Evidence Separately Applicability is best … Comparators Describe comparators, whether they reflect best alternative therapy, and how this may impact … For comparators, describe each, whether they reflect the best alternative therapy, and how this may impact

446. Migraine in Adults: Preventive Pharmacologic Treatments | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/migraine-prevention/research-2013
     December 01, 2019 - blockers and angiotensin inhibiting drugs are effective without bothersome harms and therefore offer the best

447. Disposition of Comments for CER 175 Total Worker Health (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_disposition-comments.pdf
     May 31, 2016 - Would like to see a short section with recommended best practices as to how to best implement new and … Given the limited evidence, we are not able to say much about the best practices for implementing new … may make the case that research is less helpful and each organization must organically build its best … TEP Reviewer #2 General This review is a high quality systematic assessment of the best available … evidence to support TWH as an evidence-based practice (even though it is considered by many to be a “best

448. With the rates of birth by cesarean section on the rise, what factors influence (and which have the greatest impact on) the probability of delivery by cesarean in low-risk women? Which interventions are most effective at reducing the risk… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/with-the-rates-of-birth-by-cesarean-section-on-the-rise-what-factors-influence-and-which-have-the-greatest-impact-on-the-probability-of-delivery-by-cesarean-in-low-risk-women-which-interventions-are-most-effective-at-reducin
     November 01, 2017 - Nominator Information Other Information About You: (optional) Please choose a description that best

449. COPD is common and respiratory failure due to COPD is an increasingly common disorder. Use of non-invasive positive pressure ventilation (NPPV) for patients with respiratory failure due to exacerbatons of COPD. Several trials and… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-an
     November 01, 2017 - Please choose a description that best describes your role or perspective: (you may select more than one

450. Thrombosis plays a a key role in the pathophysiology of myocardial infarction-a leading cause of morbidity and mortality. There have been a number of devices proposed for mechanical thrombectomy in patients with in the setting of acute… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/thrombosis-plays-a-a-key-role-in-the-pathophysiology-of-myocardial-infarction-a-leading-cause-of-morbidity-and-mortality-there-have-been-a-number-of-devices-proposed-for-mechanical-thrombectomy-in-patients-with-in-the-settin
     November 01, 2017 - Please choose a description that best describes your role or perspective: (you may select more than one

451. EHC Protocol - Allocation of Scarce Resources During Pandemics: Strategies for Policy Makers: A Rapid Evidence Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/scarce-resources-protocol.pdf
     January 01, 2013 - urgently need information and tested strategies to inform important decisions about how to make the best

452. Peripheral Artery Disease (PAD) - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk of adverse cardiovascular events (MI, stroke, cardiovascular death) in patients with PAD? Is there a… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-diffe
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453. Test-Performance-Metrics Appendixes (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/test-performance-metrics_appendixes.pdf
     January 01, 2005 - interpretation: the same medical test can be used in different settings and roles, and different measures will best

454. Diagnosis and treatment of low back pain:Key questions:In patients with low back pain, what are the benefits and harms of identifying risk factors for chronicity and targeting treatment based on assessed… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/diagnosis-and-treatment-of-low-back-painbr-key-questionsbr-olliin-patients-with-low-back-pain-what-are-the-benefits-and-harms-of-identifying-risk-factors-for-chronicity-and-targeting-treatment-based-on-assessed-riskliliin-pa
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455. Mindfulness meditation encompasses a range of meditation techniques that have been increasingly used to treat behavioral disorders, especially those associated with stress. Some of these were previously described in AHRQ Publication No.… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/mindfulness-meditation-encompasses-a-range-of-meditation-techniques-that-have-been-increasingly-used-to-treat-behavioral-disorders-especially-those-associated-with-stress-some-of-these-were-previously-described-in-ahrq-publi
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456. What is the comparative effectiveness and harms of treatments for traumatic brain injury? Preliminary Key Questions 1. What is the comparative effectiveness of the treatments for TBI for grades I-IV? 2. For patients, what are the potential… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-and-harms-of-treatments-for-traumatic-brain-injury-preliminary-key-questions-1-what-is-the-comparative-effectiveness-of-the-treatments-for-tbi-for-grades-i-iv-2-for-patients-what-are-the
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457. How can patients who have chronic diseases better prepare for critical illness and the end of life? Will a decision aid, using individualized estimates of outcomes, help shared decision making about advance care planning? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/how-can-patients-who-have-chronic-diseases-better-prepare-for-critical-illness-and-the-end-of-life-will-a-decision-aid-using-individualized-estimates-of-outcomes-help-shared-decision-making-about-advance-care-planning
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458. Does the use of Cytochrome P450 2C19 (CYP2C19) testing to predict response to clopidogrel in people: (1) with acute coronary syndrome, (2) who have suffered other cardiovascular disease-related events (e.g., ischemic stroke, symptomatic… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-
     November 01, 2017 - Nominator Information Other Information About You: (optional) Please choose a description that best

459. 1. Does mass spectrometric analysis and therapeutic monitoring of tacrolimus as compared with immunoassay analysis and therapeutic monitoring produce a) better organ survival rate, b) fewer rejections, c) less nephrotoxicity and/or d) cost… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/1-does-mass-spectrometric-analysis-and-therapeutic-monitoring-of-tacrolimus-as-compared-with-immunoassay-analysis-and-therapeutic-monitoring-produce-a-better-organ-survival-rate-b-fewer-rejections-c-less-nephrotoxicity-andor
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460. What evidence exists for programs to increase patient adherence to prescription medications? Which programs/approaches are most effective at increasing adherence for which populations and conditions? If little or no evidence exists, can… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-evidence-exists-for-programs-to-increase-patient-adherence-to-prescription-medications-which-programsapproaches-are-most-effective-at-increasing-adherence-for-which-populations-and-conditions-if-little-or-no-evidence-ex
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